Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine.Citrate-based polymers are the few bioactive polymer biomaterials used in biomedic...Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine.Citrate-based polymers are the few bioactive polymer biomaterials used in biomedicine because of their facile synthesis,controllable structure,biocompatibility,biomimetic viscoelastic mechanical behavior,and functional groups available for modification.In recent years,various multifunctional designs and biomedical applications,including cardiovascular,orthopedic,muscle tissue,skin tissue,nerve and spinal cord,bioimaging,and drug or gene delivery based on citrate-based polymers,have been extensively studied,and many of them have good clinical application potential.In this review,we summarize recent progress in the multifunctional design and biomedical applications of citrate-based polymers.We also discuss the further development of multifunctional citrate-based polymers with tailored properties to meet the requirements of various biomedical applications.展开更多
Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural plants.In this paper,a novel method of dyeing and multifunctional modification of silk fabric by impregnation with rib...Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural plants.In this paper,a novel method of dyeing and multifunctional modification of silk fabric by impregnation with riboflavin sodium phosphate was proposed,such that protein silk fabric can be endowed with bright yellow color and multi-functionality.The results of this paper confirmed that the pH and concentration of riboflavin sodium phosphate solution are critical factors for dyeing and multifunctional modification.Attractively,the photochromic performance was one of the most distinctive features of the modified silk fabric,and the dyed silk fabric turned into fluorescent green from original yellow under 365 nm ultraviolet lamp.Furthermore,the modified silk fabric exhibited good antibacterial properties with a high inhibition rate of 92%for Escherichia coli.Besides,the flame retardancy of silk fabric was significantly improved after modification.The damaged length of modified silk fabric with 40%owf riboflavin sodium phosphate was lower than 10.4 cm and passed the B1 classification.As revealed by the result of this paper,riboflavin sodium phosphate is sufficiently effective in serving as an eco-friendly multifunctional agent for strengthening the add-value of silk textiles.展开更多
基金supported by the National Natural Science Foundation of China(grant No.52172288)Special Support Program for High Level Talents of Shaanxi Province of China(grant No.TZ0278)+4 种基金the key R&D plan of Shaanxi Province of China(grant No.2021GXLH-Z-052)State Key Laboratory for Manufacturing Systems Engineering of China(grant No.sklms2021006)Young Talent Support Plan of Xi’an Jiaotong University of China(grant No.QY6J003)the Fundamental Research Funds for the Central Universities(grant No.xzy012021075)China Postdoctoral Science Foundation(grant No.2021M702644).
文摘Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine.Citrate-based polymers are the few bioactive polymer biomaterials used in biomedicine because of their facile synthesis,controllable structure,biocompatibility,biomimetic viscoelastic mechanical behavior,and functional groups available for modification.In recent years,various multifunctional designs and biomedical applications,including cardiovascular,orthopedic,muscle tissue,skin tissue,nerve and spinal cord,bioimaging,and drug or gene delivery based on citrate-based polymers,have been extensively studied,and many of them have good clinical application potential.In this review,we summarize recent progress in the multifunctional design and biomedical applications of citrate-based polymers.We also discuss the further development of multifunctional citrate-based polymers with tailored properties to meet the requirements of various biomedical applications.
基金The present work was found by Natural Science Foundation of Jiangsu Province(Grant No.BK20200868)Natural Science Fund for Universities and Colleges in Jiangsu Province(Grant No.20KJB540002).
文摘Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural plants.In this paper,a novel method of dyeing and multifunctional modification of silk fabric by impregnation with riboflavin sodium phosphate was proposed,such that protein silk fabric can be endowed with bright yellow color and multi-functionality.The results of this paper confirmed that the pH and concentration of riboflavin sodium phosphate solution are critical factors for dyeing and multifunctional modification.Attractively,the photochromic performance was one of the most distinctive features of the modified silk fabric,and the dyed silk fabric turned into fluorescent green from original yellow under 365 nm ultraviolet lamp.Furthermore,the modified silk fabric exhibited good antibacterial properties with a high inhibition rate of 92%for Escherichia coli.Besides,the flame retardancy of silk fabric was significantly improved after modification.The damaged length of modified silk fabric with 40%owf riboflavin sodium phosphate was lower than 10.4 cm and passed the B1 classification.As revealed by the result of this paper,riboflavin sodium phosphate is sufficiently effective in serving as an eco-friendly multifunctional agent for strengthening the add-value of silk textiles.
