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Attention-relation network for mobile phone screen defect classification via a few samples 被引量:1
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作者 Jiao Mao Guoliang Xu +1 位作者 Lijun He Jiangtao Luo 《Digital Communications and Networks》 SCIE CSCD 2024年第4期1113-1120,共8页
How to use a few defect samples to complete the defect classification is a key challenge in the production of mobile phone screens.An attention-relation network for the mobile phone screen defect classification is pro... How to use a few defect samples to complete the defect classification is a key challenge in the production of mobile phone screens.An attention-relation network for the mobile phone screen defect classification is proposed in this paper.The architecture of the attention-relation network contains two modules:a feature extract module and a feature metric module.Different from other few-shot models,an attention mechanism is applied to metric learning in our model to measure the distance between features,so as to pay attention to the correlation between features and suppress unwanted information.Besides,we combine dilated convolution and skip connection to extract more feature information for follow-up processing.We validate attention-relation network on the mobile phone screen defect dataset.The experimental results show that the classification accuracy of the attentionrelation network is 0.9486 under the 5-way 1-shot training strategy and 0.9039 under the 5-way 5-shot setting.It achieves the excellent effect of classification for mobile phone screen defects and outperforms with dominant advantages. 展开更多
关键词 Mobile phone screen defects A few samples relation network Attention mechanism Dilated convolution
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Graph Convolutional Networks Embedding Textual Structure Information for Relation Extraction
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作者 Chuyuan Wei Jinzhe Li +2 位作者 Zhiyuan Wang Shanshan Wan Maozu Guo 《Computers, Materials & Continua》 SCIE EI 2024年第5期3299-3314,共16页
Deep neural network-based relational extraction research has made significant progress in recent years,andit provides data support for many natural language processing downstream tasks such as building knowledgegraph,... Deep neural network-based relational extraction research has made significant progress in recent years,andit provides data support for many natural language processing downstream tasks such as building knowledgegraph,sentiment analysis and question-answering systems.However,previous studies ignored much unusedstructural information in sentences that could enhance the performance of the relation extraction task.Moreover,most existing dependency-based models utilize self-attention to distinguish the importance of context,whichhardly deals withmultiple-structure information.To efficiently leverage multiple structure information,this paperproposes a dynamic structure attention mechanism model based on textual structure information,which deeplyintegrates word embedding,named entity recognition labels,part of speech,dependency tree and dependency typeinto a graph convolutional network.Specifically,our model extracts text features of different structures from theinput sentence.Textual Structure information Graph Convolutional Networks employs the dynamic structureattention mechanism to learn multi-structure attention,effectively distinguishing important contextual features invarious structural information.In addition,multi-structure weights are carefully designed as amergingmechanismin the different structure attention to dynamically adjust the final attention.This paper combines these featuresand trains a graph convolutional network for relation extraction.We experiment on supervised relation extractiondatasets including SemEval 2010 Task 8,TACRED,TACREV,and Re-TACED,the result significantly outperformsthe previous. 展开更多
关键词 relation extraction graph convolutional neural networks dependency tree dynamic structure attention
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Analysis of Factors Related to Vasovagal Response in Apheresis Blood Donors and the Establishment of Prediction Model Based on BP Neural Network Algorithm
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作者 Xin Hu Hua Xu Fengqin Li 《Journal of Clinical and Nursing Research》 2024年第6期276-283,共8页
Objective:To analyze the factors related to vessel vasovagal reaction(VVR)in apheresis donors,establish a mathematical model for predicting the correlation factors and occurrence risk,and use the prediction model to i... Objective:To analyze the factors related to vessel vasovagal reaction(VVR)in apheresis donors,establish a mathematical model for predicting the correlation factors and occurrence risk,and use the prediction model to intervene in high-risk VVR blood donors,improve the blood donation experience,and retain blood donors.Methods:A total of 316 blood donors from the Xi'an Central Blood Bank from June to September 2022 were selected to statistically analyze VVR-related factors.A BP neural network prediction model is established with relevant factors as input and DRVR risk as output.Results:First-time blood donors had a high risk of VVR,female risk was high,and sex difference was significant(P value<0.05).The blood pressure before donation and intergroup differences were also significant(P value<0.05).After training,the established BP neural network model has a minimum RMS error of o.116,a correlation coefficient R=0.75,and a test model accuracy of 66.7%.Conclusion:First-time blood donors,women,and relatively low blood pressure are all high-risk groups for VVR.The BP neural network prediction model established in this paper has certain prediction accuracy and can be used as a means to evaluate the risk degree of clinical blood donors. 展开更多
关键词 Vasovagal response related factors Prediction BP neural network
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An aerial ammunition ad hoc network collaborative localization algorithm based on relative ranging and velocity measurement in a highly-dynamic topographic structure 被引量:1
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作者 Hao Wu Peng-fei Wu +2 位作者 Zhang-song Shi Shi-yan Sun Zhong-hong Wu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第7期231-248,共18页
In the internet of battlefield things, ammunition is becoming networked and intelligent, which depends on location information. Therefore, this paper focuses on the self-organized network collaborative localization of... In the internet of battlefield things, ammunition is becoming networked and intelligent, which depends on location information. Therefore, this paper focuses on the self-organized network collaborative localization of munitions with an aerial three-dimensional(3D) highly-dynamic topographic structure under a satellite denied environment. As for aerial networked munitions, the measurement of munitions is objectively incomplete due to the degenerated and interrupted link of munitions. For this reason, a cluster-oriented collaborative localization method is put forward in this paper. Multidimensional scaling(MDS) was first integrated with a trilateration localization method(TLM) to construct a relative localization algorithm for determining the relative location of a mobile cluster network. The information related to relative velocity was then combined into a collaborative localization framework to devise a TLM-vMDS algorithm. Finally, an iterative refinement algorithm based on scaling by majorizing a complicated function(SMACOF) was employed to effectively eliminate the influence of incomplete link observation on localization accuracy. Compared with the currently available advanced algorithms, the proposed TLM-vMDS algorithm achieves higher localization accuracy and faster convergence for a cluster of extensively networked munitions, and also offers better numerical stability and robustness for highspeed motion models. 展开更多
关键词 Highly-dynamic topographic structure MDS relative ranging Aerial ammunition ad hoc network
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Function chain neural network prediction on heat transfer performance of oscillating heat pipe based on grey relational analysis 被引量:12
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作者 鄂加强 李玉强 龚金科 《Journal of Central South University》 SCIE EI CAS 2011年第5期1733-1737,共5页
As for the factors affecting the heat transfer performance of complex and nonlinear oscillating heat pipe (OHP),grey relational analysis (GRA) was used to deal with the relationship between heat transfer rate of a loo... As for the factors affecting the heat transfer performance of complex and nonlinear oscillating heat pipe (OHP),grey relational analysis (GRA) was used to deal with the relationship between heat transfer rate of a looped copper-water OHP and charging ratio,inner diameter,inclination angel,heat input,number of turns,and the main influencing factors were defined.Then,forecasting model was obtained by using main influencing factors (such as charging ratio,interior diameter,and inclination angel) as the inputs of function chain neural network.The results show that the relative average error between the predicted and actual value is 4%,which illustrates that the function chain neural network can be applied to predict the performance of OHP accurately. 展开更多
关键词 oscillating heat pipe grey relational analysis fimction chain neural network heat transfer
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BARN:Behavior-Aware Relation Network for multi-label behavior detection in socially housed macaques
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作者 Sen Yang Zhi-Yuan Chen +5 位作者 Ke-Wei Liang Cai-Jie Qin Yang Yang Wen-Xuan Fan Chen-Lu Jie Xi-Bo Ma 《Zoological Research》 SCIE CSCD 2023年第6期1026-1038,共13页
Quantification of behaviors in macaques provides crucial support for various scientific disciplines,including pharmacology,neuroscience,and ethology.Despite recent advancements in the analysis of macaque behavior,rese... Quantification of behaviors in macaques provides crucial support for various scientific disciplines,including pharmacology,neuroscience,and ethology.Despite recent advancements in the analysis of macaque behavior,research on multi-label behavior detection in socially housed macaques,including consideration of interactions among them,remains scarce.Given the lack of relevant approaches and datasets,we developed the Behavior-Aware Relation Network(BARN)for multi-label behavior detection of socially housed macaques.Our approach models the relationship of behavioral similarity between macaques,guided by a behavior-aware module and novel behavior classifier,which is suitable for multi-label classification.We also constructed a behavior dataset of rhesus macaques using ordinary RGB cameras mounted outside their cages.The dataset included 65?913 labels for19 behaviors and 60?367 proposals,including identities and locations of the macaques.Experimental results showed that BARN significantly improved the baseline SlowFast network and outperformed existing relation networks.In conclusion,we successfully achieved multilabel behavior detection of socially housed macaques with both economic efficiency and high accuracy. 展开更多
关键词 Macaque behavior Drug safety assessment Multi-label behavior detection Behavioral similarity relation network
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A Graph with Adaptive AdjacencyMatrix for Relation Extraction
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作者 Run Yang YanpingChen +1 位作者 Jiaxin Yan Yongbin Qin 《Computers, Materials & Continua》 SCIE EI 2024年第9期4129-4147,共19页
The relation is a semantic expression relevant to two named entities in a sentence.Since a sentence usually contains several named entities,it is essential to learn a structured sentence representation that encodes de... The relation is a semantic expression relevant to two named entities in a sentence.Since a sentence usually contains several named entities,it is essential to learn a structured sentence representation that encodes dependency information specific to the two named entities.In related work,graph convolutional neural networks are widely adopted to learn semantic dependencies,where a dependency tree initializes the adjacency matrix.However,this approach has two main issues.First,parsing a sentence heavily relies on external toolkits,which can be errorprone.Second,the dependency tree only encodes the syntactical structure of a sentence,which may not align with the relational semantic expression.In this paper,we propose an automatic graph learningmethod to autonomously learn a sentence’s structural information.Instead of using a fixed adjacency matrix initialized by a dependency tree,we introduce an Adaptive Adjacency Matrix to encode the semantic dependency between tokens.The elements of thismatrix are dynamically learned during the training process and optimized by task-relevant learning objectives,enabling the construction of task-relevant semantic dependencies within a sentence.Our model demonstrates superior performance on the TACRED and SemEval 2010 datasets,surpassing previous works by 1.3%and 0.8%,respectively.These experimental results show that our model excels in the relation extraction task,outperforming prior models. 展开更多
关键词 relation extraction graph convolutional neural network adaptive adjacency matrix
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A U-Shaped Network-Based Grid Tagging Model for Chinese Named Entity Recognition
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作者 Yan Xiang Xuedong Zhao +3 位作者 Junjun Guo Zhiliang Shi Enbang Chen Xiaobo Zhang 《Computers, Materials & Continua》 SCIE EI 2024年第6期4149-4167,共19页
Chinese named entity recognition(CNER)has received widespread attention as an important task of Chinese information extraction.Most previous research has focused on individually studying flat CNER,overlapped CNER,or d... Chinese named entity recognition(CNER)has received widespread attention as an important task of Chinese information extraction.Most previous research has focused on individually studying flat CNER,overlapped CNER,or discontinuous CNER.However,a unified CNER is often needed in real-world scenarios.Recent studies have shown that grid tagging-based methods based on character-pair relationship classification hold great potential for achieving unified NER.Nevertheless,how to enrich Chinese character-pair grid representations and capture deeper dependencies between character pairs to improve entity recognition performance remains an unresolved challenge.In this study,we enhance the character-pair grid representation by incorporating both local and global information.Significantly,we introduce a new approach by considering the character-pair grid representation matrix as a specialized image,converting the classification of character-pair relationships into a pixel-level semantic segmentation task.We devise a U-shaped network to extract multi-scale and deeper semantic information from the grid image,allowing for a more comprehensive understanding of associative features between character pairs.This approach leads to improved accuracy in predicting their relationships,ultimately enhancing entity recognition performance.We conducted experiments on two public CNER datasets in the biomedical domain,namely CMeEE-V2 and Diakg.The results demonstrate the effectiveness of our approach,which achieves F1-score improvements of 7.29 percentage points and 1.64 percentage points compared to the current state-of-the-art(SOTA)models,respectively. 展开更多
关键词 Chinese named entity recognition character-pair relation classification grid tagging U-shaped segmentation network
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Ethanol extract of cassia seed alleviates metabolic dysfunction-associated steatotic liver disease by acting on multiple lipid metabolism-related pathways
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作者 Wen Li Jia Wang +10 位作者 YilianYang Chunlei Duan Bing Shao Mingxiu Zhang Jiapan Wang Peifeng Li Ye Yuan Yan Zhang Hongyu Ji Xingda Li Zhimin Du 《Frigid Zone Medicine》 2024年第3期160-176,共17页
Background and objective:In northern China's cold regions,the prevalence of metabolic dysfunction-associated steatotic liver disease(MASLD)exceeds 50%,significantly higher than the national and global rates.MASLD ... Background and objective:In northern China's cold regions,the prevalence of metabolic dysfunction-associated steatotic liver disease(MASLD)exceeds 50%,significantly higher than the national and global rates.MASLD is an important risk factor for cardiovascular and cerebrovascular diseases,including coronary heart disease,stroke,and tumors,with no specific therapeutic drugs currently available.The ethanol extract of cassia seed(CSEE)has shown promise in lowering blood lipids and improving hepatic steatosis,but its mechanism in treating MASLD remains underexplored.This study aims to investigate the therapeutic effects and mechanisms of CSEE.Methods:MASLD models were established in male Wistar rats and golden hamsters using a high fat diet(HFD).CSEE(10,50,250 mg/kg)was administered via gavage for six weeks.Serum levels of total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),aspartate aminotransferase(AST),and alanine aminotransferase(ALT),as well as liver TC and TG,were measured using biochemical kits.Histopathological changes in the liver were evaluated using Oil Red O staining,Hematoxylin-eosin(H&E)staining,and transmission electron microscopy(TEM).HepG2 cell viability was assessed using the cell counting kit-8(CCK8)and Calcein-AM/PI staining.Network pharmacology was used to analyze drug-disease targets,and western blotting was used to confirm these predictions.Results:CSEE treatment significantly reduced serum levels of TC,TG,LDL-C,ALT,and AST,and improved liver weight,liver index,and hepatic lipid deposition in rats and golden hamsters.In addition,CSEE alleviated free fatty acid(FFA)-induced lipid deposition in HepG2 cells.Molecular biology experiments demonstrated that CSEE increased the protein levels of p-AMPK,p-ACC,PPARα,CPT1A,PI3K P110 and p-AKT,while decreasing the protein levels of SREBP1,FASN,C/EBPα,and PPARγ,thus improving hepatic lipid metabolism and reducing lipid deposition.The beneficial effects of CSEE were reversed by small molecule inhibitors of the signaling pathways in vitro.Conclusion:CSEE improves liver lipid metabolism and reduces lipid droplet deposition in Wistar rats and golden hamsters with MASLD by activating hepatic AMPK,PPARα,and PI3K/AKT signaling pathways. 展开更多
关键词 cassia seed ethanol extract metabolic dysfunction related fatty liver disease network pharmacology
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An Empirical Study on Strategic Network,Relational Capability and Operating Performance of Agricultural Enterprises
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作者 Meihua YIN Jianhui WU 《Asian Agricultural Research》 2015年第11期5-11,共7页
By establishing the theoretical model of " strategic network cooperation-relational capability-operating performance" and structural equation,we conduct a sampling survey on 208 agricultural enterprises,and ... By establishing the theoretical model of " strategic network cooperation-relational capability-operating performance" and structural equation,we conduct a sampling survey on 208 agricultural enterprises,and use Spss21. 0 and Amos21. 0 for empirical analysis of influence of three factors in strategic network cooperation( market futurity,trusting relationship and business networks) on market relational capability and operating performance of agricultural enterprises. The results show that the establishment of trusting relationship and business networks in strategic networks has a positive impact on the operating performance of agricultural enterprises,and relational capability plays a fully mediating role while relational capability has not mediating effect on market futurity. This study provides a meaningful reference for the follow-up studies on relational capability and operating performance of agricultural enterprises,to further enhance the operating performance of agricultural enterprises and effectively improve farmers' income. 展开更多
关键词 MARKET FUTURITY Trusting relationship BUSINESS networks relational CAPABILITY Operating performance
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Study on Influence of Farmers' Relational Network on Their Undertaking Process
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作者 LI Chao-dong,YU Tong-tao College of Sociology and Political Science,Anhui University,Hefei 230601,China 《Asian Agricultural Research》 2012年第3期41-45,共5页
We elaborate relevant theories of farmers' relational network,including the Differential Model of Association,the Strength of Weak Tie,Strength of Strong Tie and Favor and Face.The farmers' relational network ... We elaborate relevant theories of farmers' relational network,including the Differential Model of Association,the Strength of Weak Tie,Strength of Strong Tie and Favor and Face.The farmers' relational network in the Differential Model of Association can be divided into three layers:strong tie,weak tie and irrelative relationship according to Granovetter theory.These three layers have deep influence on opportunity selection during the undertaking,financing and enterprise development.With rational knowledge of these layers,farmers may exploit undertaking resources.On the basis of these,we made detailed analysis on farmers' selection of relations in the opportunity selection,financing and enterprise development stages. 展开更多
关键词 relational network Farmer’s undertaking Differenti
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Clues from networks:quantifying relational risk for credit risk evaluation of SMEs
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作者 Jingjing Long Cuiqing Jiang +1 位作者 Stanko Dimitrov Zhao Wang 《Financial Innovation》 2022年第1期2467-2507,共41页
Owing to information asymmetry,evaluating the credit risk of small-and mediumsized enterprises(SMEs)is difficult.While previous studies evaluating the credit risk of SMEs have mostly focused on intrinsic risk generate... Owing to information asymmetry,evaluating the credit risk of small-and mediumsized enterprises(SMEs)is difficult.While previous studies evaluating the credit risk of SMEs have mostly focused on intrinsic risk generated by SMEs,our study considers both intrinsic and relational risks generated by neighbor firms’publicly available risk events.We propose a framework for quantifying relational risk based on publicly available risk events for SMEs’credit risk evaluation.Our proposed framework quantifies relational risk by weighting the impact of publicly available risk events of each firm in an interfirm network—considering the impact of interfirm network type,risk event type,and time dependence of risk events—and combines the relational risk score with financial and demographic features to evaluate SMEs credit risk.Our results reveal that relational risk score significantly improves both discrimination and granting performances of credit risk evaluation of SMEs,providing valuable managerial and practical implications for financial institutions. 展开更多
关键词 SMES Credit risk evaluation Interfirm network Risk event relational risk
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An Evaluation Algorithm for Importance of Dynamic Nodes in Social Networks Based on Three-Dimensional Grey Relational Degree
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作者 Xiaolong Li Yiliang Han +1 位作者 Deyang Zhang Xuguang Wu 《国际计算机前沿大会会议论文集》 2018年第2期18-18,共1页
关键词 Social networks DYNAMIC nodesThree-dimensional GREY relational degree
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Multi objective prediction and optimization of control parameters in the milling of aluminium hybrid metal matrix composites using ANN and Taguchi-grey relational analysis 被引量:3
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作者 S.Ajith Arul Daniel R.Pugazhenthi +1 位作者 R.Kumar S.Vijayananth 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2019年第4期545-556,共12页
This study aims to optimize the input parameters such as mass fraction and particle size of SiC along with depth of cut,feed and cutting speed in the milling of Al5059/SiC/MoS2.The hybrid metal matrix composites are g... This study aims to optimize the input parameters such as mass fraction and particle size of SiC along with depth of cut,feed and cutting speed in the milling of Al5059/SiC/MoS2.The hybrid metal matrix composites are generally fabricated by reinforcing of different sizes(10,20,40 μm)of SiC with aluminium at a different levels(5%,10%& 15%)whereas the MoS2 addition is fixed as 2%.The effect of each control factor on response variables are analyzed through Taguchi S/N ratio method.Also,the most significant method for prediction of response parameters is satisfied by ANN model than the regression model.Analysis of variance(ANOVA)results envisage that mass fraction of SiC,feed rate is the most domineering factor on response variable. 展开更多
关键词 Silicon CARBIDE Temperature Surface roughness Cutting FORCES Artificial neural network GREY relational analysis
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Material component to non-linear relation between sediment yield and drainage network development:an flume experimental study 被引量:2
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作者 JIN De-sheng, CHEN Hao, GUO Qing-wu (Institute of Geographic Sciences and Natural Resources Research, CAS, Beijing 100101, China) 《Journal of Geographical Sciences》 SCIE CSCD 2001年第3期271-281,共11页
This paper examines the experimental study on influence of material component to non-linear relation between sediment yield and drainage network development completed in the Lab. The area of flume drainage system is 8... This paper examines the experimental study on influence of material component to non-linear relation between sediment yield and drainage network development completed in the Lab. The area of flume drainage system is 81.2 m2, the longitudinal gradient and cross section slope are from 0.0348 to 0.0775 and from 0.0115 to 0.038, respectively. Different model materials with a medium diameter of 0.021 mm, 0.076 mm and 0.066 mm cover three experiments each. An artificial rainfall equipment is a sprinkler-system composed of 7 downward nozzles, distributed by hexagon type and a given rainfall intensity is 35.56 mm/hr.cm2. Three experiments are designed by process-response principle at the beginning the ψ shaped small network is dug in the flume. Running time spans are 720 m, 1440 minutes and 540 minutes for Runs I, IV and VI, respectively. Three experiments show that the sediment yield processes are characterized by delaying with a vibration. During network development the energy of a drainage system is dissipated by two ways, of which one is increasing the number of channels (rill and gully), and the other one is enlarging the channel length. The fractal dimension of a drainage network is exactly an index of energy dissipation of a drainage morphological system. Change of this index with time is an unsymmetrical concave curve. Comparison of three experiments explains that the vibration and the delaying ratio of sediment yield processes increase with material coarsening, while the number of channel decreases. The length of channel enlarges with material fining. There exists non-linear relationship between fractal dimension and sediment yield with an unsymmetrical hyperbolic curve. The absolute value of delaying ratio of the curve reduces with time running and material fining. It is characterized by substitution of situation to time. 展开更多
关键词 material component network sediment yield nonlinear relation EXPERIMENT
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Relationships Between Fractal Road and Drainage Networks in Wuling Mountainous Area:Another Symmetric Understanding of Human-Environment Relations 被引量:2
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作者 LIU Cheng-liang DUAN De-zhong ZHANG Hong 《Journal of Mountain Science》 SCIE CSCD 2014年第4期1060-1069,共10页
Symmetrical relationships between humans and their environment have been referred to as an extension of symmetries in the human geographical system and have drawn great attention. This paper explored the symmetry betw... Symmetrical relationships between humans and their environment have been referred to as an extension of symmetries in the human geographical system and have drawn great attention. This paper explored the symmetry between physical and human systems through fractal analysis of the road and drainage networks in Wuling mountainous area. We found that both the road and drainage networks reflect weak clustering distributions. The evolution of the road network shared a significant self-organizing composition, while the drainage network showed obvious double fraetal characteristics. The geometric fractal dimension of the road network was larger than that of the drainage network. In addition, when assigned a weight relating to hierarchy or length, neither the road network nor drainage network showed a fractal property. These findings indicated that the fractal evolution of the road network shared certain similarities with fractal distribution of the drainage network. The symmetry between the two systems resulted from an interactive process of destroying symmetry at the lower order and reconstructing symmetry at the higher order. The relationships between the fractal dimensions of the rural-urban road network, the drainage network andthe urban system indicated that the development of this area was to achieve the symmetrical isomorphism of physical-human geographical systems. 展开更多
关键词 Fractal road network Fractal drainagenetwork SYMMETRY Human-environment relation SELF-ORGANIZATION
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Neural Network Model for the Constitutive Relations of Soil 被引量:1
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作者 Zeng Jing, Wang J ing\|tao School of Civil Engineering and Mechanics, Huazhong University of Science and Technology, Wuhan 430074, Hubei, China 《Wuhan University Journal of Natural Sciences》 CAS 2003年第01A期86-90,共5页
The soil constitutive relation is one of the important issues in soil mechanics. It is very difficult to establish mathematical models because of the complexity of soil mechanical behavior.... The soil constitutive relation is one of the important issues in soil mechanics. It is very difficult to establish mathematical models because of the complexity of soil mechanical behavior. We propose a new method of neural network analysis for establishing soil constitutive models. Based on triaxial experiments of sand in the laboratory, the nonlinear constitutive models of sand expressed by the neural network were set up. In comparison with Duncan\|Chang's model, the neural network method for sand modeling has been proved to be more convenient, accurate and it has a strong fault\|tolerance function. 展开更多
关键词 neural network constitutive relations constitutive model
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Molecular mechanisms of Baihedihuang decoction as a treatment for breast cancer related anxiety:A network pharmacology and molecular docking study 被引量:2
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作者 Zhong-Hui Li Guo-Hua Yang Fang Wang 《World Journal of Clinical Cases》 SCIE 2022年第33期12104-12115,共12页
BACKGROUND The therapeutic effects of a combination of Chinese medicines called Baihedihuang decoction(BD)have been clinically verified,although its molecular targets in breast cancer related anxiety remain unknown.AI... BACKGROUND The therapeutic effects of a combination of Chinese medicines called Baihedihuang decoction(BD)have been clinically verified,although its molecular targets in breast cancer related anxiety remain unknown.AIM To explore the molecular mechanisms of BD for breast cancer related anxiety treatment.METHODS We used the Traditional Chinese Medicine Systems Pharmacology database to screen the active ingredients and potential targets of BD,and constructed the"drug-ingredient-target"network map with the help of Cytoscape 3.8 software.Also,we used the Online Mendelian Inheritance in Man,DrugBank,and Gencards databases to collect the disease targets of breast cancer related anxiety,and used the STRING platform to perform protein interaction analysis and construct the protein-protein interaction network.Metascape platform was used for Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis of key targets.Molecular docking technology was used to verify the drug component/target disease network.RESULTS We screened 16 active ingredients of BD for breast cancer related anxiety,with 113 target proteins.There are 931 disease targets of breast cancer related anxiety,and finally,43 key targets and 305 Kyoto Encyclopedia of Genes and Genomes pathways were generated.The main active ingredients of BD for breast cancer related anxiety are verbascoside,β-sitosterol,stigmasterol,catalpol,etc.CDK2,TP53,HTR2A,ESR1,etc.are its key targets,and the main involved signaling pathways may include neuroactive ligand-receptor interaction pathway,5-hydroxytryptaminergic synapse,P53 signaling pathway,cGMP-PKG signaling pathway,the cAMP signaling pathway,etc.Finally,molecular docking was performed with Vina software to validate the key active ingredients in BD with the selected key action targets.The molecular docking results showed that verbascoside,β-sitosterol,stigmasterol and CDK2 could stably bind and interact through amino acid residues SER249,ARG260,PRO228,ALA282,SER276,LYS273,ASN272,etc.CONCLUSION The therapeutic effect of BD for breast cancer related anxiety is multi-level,multi-target,and multi-pathway.The findings of this study provide ideas and basis for further research. 展开更多
关键词 network pharmacology Molecular docking Baihedihuang decoction Breast cancer related anxiety Mechanism of action
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Spatial Interaction Network Analysis of Crude Oil Trade Relations between Countries along the Belt and Road 被引量:2
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作者 Qixin WANG Kun QIN +4 位作者 Donghai LIU Gang XU Yanqing XU Yang ZHOU Rui XIAO 《Journal of Geodesy and Geoinformation Science》 2022年第2期60-74,共15页
Based on the theories and methods of complex network,crude oil trade flows between countries along the Belt and Road(B&R,hereafter)are inserted into the Geo-space of B&R and form a spatial interaction network ... Based on the theories and methods of complex network,crude oil trade flows between countries along the Belt and Road(B&R,hereafter)are inserted into the Geo-space of B&R and form a spatial interaction network which takes the countries as nodes and takes the trade relations as edges.The networked mining and evolution analysis can provide important references for the research on trade relations among the B&R countries and the formulation of trade policy.This paper researches and discusses the construction,statistical analysis,top networks and stability of the crude oil trade network between the B&R countries from 2001 to 2020 from the perspectives of Geo-Computation for Social Sciences(GCSS)and spatial interaction.Firstly,evolutions of out-degree,in-degree,out-strength and in-strength of the top 10 countries in the crude oil trade network are computed and analyzed.Secondly,the top network method is used to explore the evolution characteristics of hierarchical structures.And finally,the sequential evolution characteristics of the crude oil trade network stability are analyzed utilizing the network stability measure method based on the trade relationship autocorrelation function.The analysis results show that Russia has the largest out-degree and out-strength,and China has the largest in-degree and in-strength.The crude oil trade volume of the top 10 import and export networks between 2001—2020 accounts for over 90%of the total trade volume of the crude oil trade network,and the proportion remains relatively stable.However,the stability of the network showed strong fluctuations in 2009,2012 and 2014,which may be closely related to major international events in these years,which could furtherly be used to build a correlation model between network volatility and major events.This paper explores how to construct and analyze the spatial interaction network of crude oil trade and can provide references for trade relations research and trade policy formulation of B&R countries. 展开更多
关键词 spatial interaction network Geo-Computation for Social Sciences(GCSS) the Belt and Road Initiative(BRI) trade relation network stability
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Joint Self-Attention Based Neural Networks for Semantic Relation Extraction 被引量:1
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作者 Jun Sun Yan Li +5 位作者 Yatian Shen Wenke Ding Xianjin Shi Lei Zhang Xiajiong Shen Jing He 《Journal of Information Hiding and Privacy Protection》 2019年第2期69-75,共7页
Relation extraction is an important task in NLP community.However,some models often fail in capturing Long-distance dependence on semantics,and the interaction between semantics of two entities is ignored.In this pape... Relation extraction is an important task in NLP community.However,some models often fail in capturing Long-distance dependence on semantics,and the interaction between semantics of two entities is ignored.In this paper,we propose a novel neural network model for semantic relation classification called joint self-attention bi-LSTM(SA-Bi-LSTM)to model the internal structure of the sentence to obtain the importance of each word of the sentence without relying on additional information,and capture Long-distance dependence on semantics.We conduct experiments using the SemEval-2010 Task 8 dataset.Extensive experiments and the results demonstrated that the proposed method is effective against relation classification,which can obtain state-ofthe-art classification accuracy just with minimal feature engineering. 展开更多
关键词 Self-attention relation extraction neural networks
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