A patient with Anti-N-methyl-D-aspartate receptor(NMDAR)encephalitis presented with quadriplegia and multiple peripheral neuropathy with axonal lesion,confirmed by electrophysiological examination.The muscle strength ...A patient with Anti-N-methyl-D-aspartate receptor(NMDAR)encephalitis presented with quadriplegia and multiple peripheral neuropathy with axonal lesion,confirmed by electrophysiological examination.The muscle strength in the limbs of the patient gradually recovered almost completely,accompanied by the reversal of neuroelectrophysiological symptoms,and the improvement of clinical manifestations,including consciousness,respiration and cognitive function.It was revealed that the neuropathy in NMDAR encephalitis involved motor or sensorimotor nerves more than pure sensory nerves.No autoantibodies were detectable,in contrast to other anti-NMDAR overlapping syndromes.Although the underlying mechanism remains unclear,it may be associated with autoimmune generalization.In conclusion,when patients with NMDAR encephalitis present with severe limb paralysis,the possibility of peripheral nerve damage should be considered.展开更多
Objective To compare the clinical efficacy between acupuncture and intravenous administration of lipoic acid and alprostadil for distal symmetric multiple peripheral neuropathy of diabetes mellitus.Methods Sixty patie...Objective To compare the clinical efficacy between acupuncture and intravenous administration of lipoic acid and alprostadil for distal symmetric multiple peripheral neuropathy of diabetes mellitus.Methods Sixty patients were randomly divided into an acupuncture group(31 cases)and a medication group(29 cases).Patients in the two groups received basic treatment to control blood sugar within a safe range.On this basis,patients in the acu-展开更多
文摘A patient with Anti-N-methyl-D-aspartate receptor(NMDAR)encephalitis presented with quadriplegia and multiple peripheral neuropathy with axonal lesion,confirmed by electrophysiological examination.The muscle strength in the limbs of the patient gradually recovered almost completely,accompanied by the reversal of neuroelectrophysiological symptoms,and the improvement of clinical manifestations,including consciousness,respiration and cognitive function.It was revealed that the neuropathy in NMDAR encephalitis involved motor or sensorimotor nerves more than pure sensory nerves.No autoantibodies were detectable,in contrast to other anti-NMDAR overlapping syndromes.Although the underlying mechanism remains unclear,it may be associated with autoimmune generalization.In conclusion,when patients with NMDAR encephalitis present with severe limb paralysis,the possibility of peripheral nerve damage should be considered.
文摘Objective To compare the clinical efficacy between acupuncture and intravenous administration of lipoic acid and alprostadil for distal symmetric multiple peripheral neuropathy of diabetes mellitus.Methods Sixty patients were randomly divided into an acupuncture group(31 cases)and a medication group(29 cases).Patients in the two groups received basic treatment to control blood sugar within a safe range.On this basis,patients in the acu-
