计及多目标约束的成品卷烟销售订单配送调度优化

针对制造业供应链中的跨地域多运输中心大数据订单物流调度问题,对涉及多约束条件和多目标的异构运输车辆调度问题展开研究。根据烟草制造工业的实际运输任务需求,考虑制造订单安排、车辆准运证限制、运输车辆物理限制、运输时间窗、排产出库时间等实际约束,搭建了以包括车辆等待卷烟出库的最短运输时间,最低运输费用及最高车辆利用率为优化目标的成品烟物流车辆跨地域调度优化模型。设计了基于差分进化的混合多元宇宙算法(DE-MVO)用以解决该模型。最后基于某烟草工业企业的实际生产订单数据进行实验,将所设计的算法分别与粒子群(PSO)算法、差分进化(DE)算法、鲸鱼优化(WOA)算法、遗传优化(GA)算法、乌鸦搜索(CSA)算法、天鹰座优化器(AO)、多元宇宙(MVO)等前沿算法进行横向对比,对比结果表明所设计的算法在全局搜索能力、寻优精度等方面更优于其他算法,进一步表明所建立的模型在求解制造业供应链运输车辆调度问题中具有可行性。

基于改进的多元宇宙算法的晶圆生产调度算法

针对以最小化最大完工时间为目标的晶圆生产制造系统的调度问题,提出了改进的多元宇宙算法。根据晶圆生产制造系统的特征,构建了一个整数规划模型。针对原始多元宇宙算法的局限性,分别从使用启发式规则生成初始种群、重新定义向最优宇宙移动策略和宇宙更新策略三个方面对算法进行改进。将原始多元宇宙算法、遗传算法、NEH启发式算法、迭代贪婪算法以及通过不同策略改进的多元宇宙算法进行对比实验,结果表明,所提方法可以高效地解决晶圆制造过程中的复杂现象。

Expanding the Boundaries of the Chemical Space of DNA Methyltransferase 1 Modulators

DNA methyltransferase 1 (DNMT1), one of the main epigenetic targets, is involved in the duplication of the DNA methylation pattern during replication, and it is essential for proper mammalian development. Small molecule DNMT1 modulators are attractive for biochemical epigenetic studies and have the potential to become drugs. So far, more than five hundred small molecules have been reported as DNMT1 inhibitors. However, only a limited number of DNMT1 activators have been disclosed because, at least in part, DNMT1 activators are typically regarded as negative data in virtual screening campaigns or optimization projects. This manuscript aims to report the chemical structures and biological activity of small molecules that increase the enzymatic activity of DNMT1. Results of the biochemical experimental assays are discussed. It was found that small molecule activators have a large variety of chemical scaffolds but share pharmacophore features. Visual analysis of the chemical space and multiverse based on molecular fingertips supported that activators are structurally diverse. This is the first report of eight small molecules that increase the enzymatic activity of DNMT1 by more than 400% in an enzymatic-based assay. The outcome warrants further investigation of the epigenetic activity of the compounds in a counter-screen assay, e.g., cell-based and in vivo context.

Multiverse and the Time State

This article is not inspired by any religion or quantum many-worlds interpretation. The mathematics of multiverse is presented here. The mass operator was introduced earlier by Alnobani. This operator is used here to deduce the time state. It is found that time has four states and those four states are orthogonal. Time is the constitution of any verse. Time has direction. Every orthogonal direction of time belongs to a verse. Past and future belong to opposite directions of time and they are arbitrary. Other verses are there by their own and not a probabilities of any other verse and if any similarity it is only a coincidence. Among applications of this thesis is travelling through groups of galaxies, or more or less.

Multiverse Theory

In this paper it is answered why the imaginary number is not used in the equal operator presented earlier by Ahiobani. The life criterion is presented here. The concept of energy conservation is assumed to be held within the gates between verses. The Hamiltonian for entry is the some when exiting, this concept is discussed. Within this concept suvat equations are discussed. Ahiobani＇ s generalized factor is presented instead of Planck＇s constant as proportionality factor between energy and frequency. A closer physical look for multiverse mathematics as tensor product is performed.

A Cosmological Neuroscientific Examination of Bertrand Russell’s Essays on Religion and Related Subjects

This work examined Bertrand Russell’s main arguments against the existence of God and his strongly negative opinion on the historic role of religions.These arguments were:(1)The idea that God is a First Cause is invalid because the cosmos doesn’t have to have a beginning;(2)If there were reasons for God to issue the observed natural laws and not others then God Himself was just an intermediary of older laws;(3)Considering all the defects of the world one cannot consider God as an omnipotent designer;(4)If God created both right and wrong then it is no longer a significant statement that God is good;And(5)most people believe in God just because they have been taught from early infancy to do it.The criticisms of cosmological neuroscience were as follows:(1)The particular cosmic wave that carries our Universe could have a beginning;(2)Although there were reasons for the natural laws which God issued,it cannot diminish the divine creativity of this act;(3)Although the world is indeed full of defects,they are as much parts of the cosmic order as its splendors,due to their common roots in the Law of Coexistence in Diversity;(4)Although right and wrong may ultimately be both in God’s blueprint,He is still benevolent due to the Law of Divine-Evil Asymmetry permitting wrong only under the dominance of right;And(5)although many believe in God only because they were taught to do so and hope it provides safety,this is an oversimplification unable to explain the genuine Faith of others.The devastating judgement of Russel that religions have been just“a source of untold misery to the human race”was also examined.This brief article could not detail all the positive social changes with which the religions of goodness(e.g.,Abrahamic religions)enriched history,such as introducing the respect for human life.But the paper did remind the reader of the God-inspired work of Lao Tzu,Rumi,Michelangelo,the Bach-interpreting Leonard Bernstein,Mother Teresa,Martin Luther King Jr.,George Harrison and others including the architects of the Borobudur temple and astronauts like Frank Borman who read from the Bible while flying around the Moon.The paper ended with the central thought of Bertrand Russell that“The good life is one inspired by love and guided by knowledge”,to emphasize that if committed to their Conscience atheists like him can live as moral lives as the men and women of Faith—the difference is being nothing else than sensing or not the Soul that permeates the cosmos.

Aspirations on the Bright Side of Humanity: It is Time to Translate Aspirations Into Actions With Establishing the Government of Earth

The thesis of this paper is that the digital noosphere of the World Wide Web and its users,the borderless move of virtually all resources of the planet,and the consequent globalization of most aspects of national politics,economy,and culture,along with the increasing difficulty of controlling the related high-tech military conflicts,human-made environmental crises,and the abnormal migrations of abused people now make it inevitable to leave behind the competitive international chaos rooted in humankind’s animal past and turn to the cooperative social spirit recommended by Aristotle,Lao Tzu,Jesus,Dante,H.G.Wells,Martin Luther King Jr.,John Lennon,Nicholas Hagger,and others to finally translate their aspirations into actions via establishing the Government of Earth for the decent and free.The paper presents a five-step,15-year,~$25B plan to start this process.That this plan has nothing to do with the Godless work of secret societies,the authoritarian urges of renewed fascism or the political absurdities of Marxism-Leninism it is relayed by the envisioned Intercontinental Education System of the outlined Government of Earth to teach every child on the planet-via a new community of digitally linked extraordinary teachers-for the beauty of lifelong learning,tolerance,duty,honor,free cooperation,and artful communication for divine missions.

交叉性和去中心化叙事:《瞬息全宇宙》对多元宇宙设定的创造性运用

《瞬息全宇宙》(EEAAO)由美国知名独立电影工作室A24出品,以融合复杂主题的叙事为鲜明特征。本文剖析了这部影片的叙述逻辑,尤其对多元宇宙这一叙事设定的熟练运用。笔者认为编导双人组丹尼尔·关和丹尼尔·施因内特巧妙运用多元宇宙这个设定,来探索移民内部存在的种族和文化冲突以及他们与美国政府之间的冲突,这标志着多元宇宙叙事迎来了新的文化里程碑。此外,影片中的多元宇宙概念也是一种隐喻,深入探讨了父权社会中女性的边缘化和酷儿经历,揭示了伊芙琳和乔伊体现的复杂交叉性身份。最后,通过阐明多元宇宙与影片“去中心化”叙事的融合,本文探讨了A24在塑造好莱坞电影未来中的可能作用,并指出《瞬息全宇宙》不仅仅是一部电影,更是引领行业叙事和表现形式进化的灯塔。

基于GCA-MVO-ICA优化BP的负荷预测研究

为提高微网负荷预测的精度,提出来一种利用灰色关联度分析优化BP神经网络优化输入层数据,利用新型的多元宇宙算法优化隐含层权重,采用帝国竞争算法优化输出层结果的逐层优化模型,对2组实测数据算例分析。结果表明,所提GCA-MVO-ICA优化BP网络的方法能够提高微网负荷的预测精度,并且具有较好的普适性。

查尔斯·詹克斯的多元宇宙景观设计研究

文章以多元宇宙景观设计理论为研究对象。查尔斯·詹克斯是重要的建筑理论家及景观设计师,创建了多元宇宙景观设计的理论基础。首先阐释多元宇宙的基本概念及研究现状,进而研究詹克斯生平及其多元宇宙设计理论。通过典型案例分析,初步概括了多元宇宙景观设计的特征,包括:东西方融合的设计观念;象征主义的设计手法;灵动的空间形态;抽象的设计表现形式等。同时论述了这一理论对我国景观设计实践的影响。这一理论的发展和演变还需时间的检验。

Hidden Multiverse Extraterrestrial Super Civilizations

Theoretical and experimental evidence of physical reality of imaginary numbers using interpretation of Ohm’s law for electrical AC circuits proposed in 1897 by Steinmetz was presented. Other pieces of evidence are mentioned as well. The use of the general scientific principle of the physical reality of imaginary numbers allowed to prove that the relativistic formulas in the existing version of the special relativity theory are wrong, as well as to deny the principle of non-exceeding the speed of light and the hypothesis of monoverse. Corrected relativistic formulas are given and on their basis a theory of hidden Multiverse is proposed, parallel universes of which are mutually invisible. Using data obtained by the spacecrafts WMAP and Planck, it is proved that the hidden Multiverse has a quaternion structure, exists in the six-dimensional space, and forms Hyperverse together with other Multiverses. It is shown that the parallel universes of the hidden Multiverse are continuously drifting in multidimensional space, touch each other in many places and are even partially immersed in each other, forming portals. It is alleged that the search for extraterrestrial life in deep space is devoid of meaning, as you can even walk to the adjacent parallel universes through portals, which are anomalous zones on Earth. Moreover, extraterrestrial super civilizations have already found us long time ago and are located on Earth. The attempts to contact these super civilizations are meaningless as well, because such contacts are possible only at their wish. Consequently, to make the contacts possible, we need to convince super civilizations that human civilization is of interest to them and that it has a sufficiently high intelligence. It is shown how the human super intelligence over can be realized.

Antimatter Multiverses

The probability of creating Antimatter Multiverses is the same as the probability of creating Matter Multiverses since the Laws of Physics do not differentiate between matter and antimatter. The interaction of Matter and Antimatter Multiverses would destroy all the lower dimensions of both Multiverses allowing only the higher dimensions of the bigger Multiverse to survive. Energy within the void builds both types of Multiverses. Entropy within the void ends the building process to send all the mass back into the original levels of the void as Energy that is continuously being exchanged between the void and the two kinds of Multiverses.

Hypothesis of the Hidden Multiverse Explains Dark Matter and Dark Energy

Analysis of WMAP and Planck spacecraft data has proved that we live in an invisible Multiverse, referred to as hidden, that has a quaternion structure. It explains the reason for the mutual invisibility of parallel universes contained in the hidden Multiverse. It is shown that the hidden Multiverse includes most likely twenty parallel universes from different dimensions, six of which are adjacent to our universe. Besides, edges of the hidden Multiverse are connected to other (from one to four) Multiverses, which are observable neither by electromagnetic nor by gravitational manifestations. The Multiverse described contains four matter-antimatter pairs, annihilation of which is prevented by relative spatial position of the universes. The experimental proof of existence of the hidden Multiverse is explained to be the phenomenon of dark matter and dark energy that correspond to other invisible parallel universes, except ours, included in the hidden Multiverse. General scientific principle of physical reality of imaginary numbers, refuting some of the statements of the existing version of the special theory of relativity, is a physical and mathematical foundation of the outlined conception of the hidden Multiverse. The article presents relativistic formulas of the theory of special relativity adjusted in accordance with the principle. It also offers appropriate interpretation of multidimensional space of the hidden Multiverse.

Dark Energy, Dark Matter, and the Multiverse

Our third spatial dimension (3-D) is currently in the process of building the fourth spatial dimension. Dark Energy is being used to create higher dimensions of space from the first to the nth, and it is also responsible for the formation and the rotation of the fourth dimension from the point singularities of the vacuum space of the third dimension. To start the creation up to the nth dimension, n! zero dimensional singularities arise simultaneously from the n = 0 level of the void. Once the creation of an n dimensional ellipsoidal matter Universe has been completed, the outward Dark Energy force ends, and then the inward force of gravity takes over to crush the n dimensional Universe into the center of the nth dimensional singularity of the void. The system is now in a non-equilibrium state because the entropy of the system has attained its lowest possible value. To bring the system back to equilibrium there will arise out of the nth dimensional void an antimatter Universe which will reverse the process to deposit all the Dark Energy back into the original levels of the void so that the net change in entropy of the system becomes zero. Dark Matter is the matter that exists in the fourth spatial dimension as 4-D matter spewed there through the Black Hole singularities of our third dimension. Ellipsoidal matter and antimatter Multiverses rotating in opposite directions are a natural byproduct of this new theory of Physics which also solves certain particle Physics problems of the Standard Model.

The Void and the Multiverse

The Void is different from the vacuum space of our Universe because it has “nothing” in it, no space, no time, no mass, and no charge. It only has Pure Energy. The only particles that have no space, no time, no mass, and no charge are photons and hence the Void is filled with photons of different Energy levels separated from one another by quantum numbers n. The Energy from within the Void is the source of all creation and annihilation. Each Universe of the Multiverse is created in parts that are joined together by gravity. Dark (Photon) Energy creates one part of the first dimension, two parts of the second dimension, three parts of the third dimension, four parts of the fourth dimension and so on, parts that are brought together to complete the formation of that dimensional Universe by means of a Big Bang;just as the Big Bang brought 3, 3-D parts created by 3, 2-D Universes together to form our 3-D Universe.

Multiverse Spacetime

A theological train of reasoning is avoided in this paper. The properties of the equal operator presented earlier by Alnobani are given here. A view of the present time is given. As a consequence of the presence of time state, the verses are arranged in couples and every verse including in which we live is a live verse in the same context of human life. This paper interferes with and changes the procedures and philosophy of mathematics itself. Space, mass and time are parts of one whole which is called simply time. The aim of this paper is to make the knowledge of its subject public, so other researchers can contribute to it. The concept of a gate between verses is investigated.

Amalgamated Geometric Structure of the Local Multiverse

We consider multiverses as time-amalgamated multiply warped products of Lorentzian (Einstein) manifolds. We define the Local Multiverse as a time-connected component associated with our physical (3 + 1)-spacetime. It is a collection of “parallel universes” with (mutually) synchronized timelines. Metaphysical considerations suggest that the Local Multiverse could be an extremely complex agglomeration with, at least, several hundred parallel universes in the Solar neighbourhood (and many thousands in galaxy bulks). In this paper we study a simplified time-almagamated globally hyperbolic model. Our picture implies the multiversality of elementary particles which are, actually, transcosmic (super)strings with multiple endpoints on parallel universes considered as D-branes.

Derivation of Multiverse from Universal Wave Function Interpretation of String Theory

The multiverse is a hypothesis created to solve certain problems in cosmology. Currently, this scheme is still largely ad hoc, rather than derived from fundamental laws and principles. Because of this, the predictive power of this theory is rather limited. Furthermore, there are concerns that this theory will make it impossible to calculate some measured quantities, such as the masses of quarks and the electron. In this paper, we will show that a new development in string theory, the universal wave function interpretation of string theory, provides a way to derive the mathematical expression of the multiverse. We will demonstrate that the Weyl invariance existing in string theory indicates that our observed universe is a projection from a hologram. We will present how the laws of physics can be derived from this fact. Furthermore, we suggest it may also provide a way to calculate the masses of fundamental particles such as quarks and the electron.

The Reversible Cyclic Universe in the Reversible Multiverse and the Reversible String Theory

The paper posits that the multiverse is reversible, so all universes in the multiverse are reversible cyclic universes which have the inexhaustible resources of space-time to expand. The collision of expanding universes is permanently irreversible, forbidden in the reversible multiverse, so every universe is surrounded by the zero-energy interuniversal void as the permanent gap among universes to keep universes apart. A zero-sum energy dual universe of positive energy universe and negative energy universe can be created in the interuniversal void, and the new dual universe is again surrounded by the interuniversal void. This paper also posits the reversible string theory with oscillating space-time dimension number oscillating between 11D (space-time dimension) and 4D without the conventional compactization of string. Dimension number decreases with decreasing speed of light, decreasing vacuum energy, and increasing rest mass. The 4D and the 11D have zero and the highest vacuum energies, respectively. The universes in the reversible multiverse oscillate reversibly between high and low dimension numbers. Under symmetry breaking as in our universe, the positive energy universe as our observed universe absorbed the interuniversal void, while the negative energy universe did not. The interuniversal void has zero vacuum energy, so the absorption of the interuniversal void by the positive energy universe forced the positive energy 10D universe with high vacuum energy to be transformed into the positive energy 4D universe with zero vacuum energy, resulting in the inflation followed by the Big Bang. The negative energy universe undergoes dimension number oscillation between 4D and 10D dimension by dimension. The negative energy >4D universe is hidden, and the negative energy 4D universe appears as dark energy. The calculated percentages of dark energy, dark matter, and baryonic matter and the calculated time for dark energy to start are in good agreements with the observed values.

Hyperverse, 5-Dimensional Gravity and Multiverses as Nested Gogberashvili Shells

We consider the Hyperverse as a collection of multiverses in 5-dimensional spacetime with gravitational constant G. Each multiverse in our simplified model is a bouquet of nested spherical Gogberashvili shells. If gk is the gravitational constant of a thin shell Sk and εk, its thickness then G ~ εkgk. The physical universe is supposed to be one of those shells inside the local nested bouquet called Local Multiverse. We relate this construction to Robinson-Trautman metrics describing expanding spacetimes with spherical gravitational waves. Supermassive astronomical black holes, located at cores of elliptic/spiral galaxies, are also conjecturally described within this theory. Our constructions are equally consistent with the modern theory of cosmological coupling.