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The Effect of Andrographis Paniculata Nees(APN)in Alleviating the Myocardial Ischemic Reperfunion Injury
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作者 郭志凌 赵华月 郑信华 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 1994年第1期49-51,共3页
In experimental dogs,the effect of APN in alleviating the ischemiareperfusion injury was prominent.Compared with the sustained isthmian group,superoxide dismutast(SOD)in the ischemic region of myocardial tissue in the... In experimental dogs,the effect of APN in alleviating the ischemiareperfusion injury was prominent.Compared with the sustained isthmian group,superoxide dismutast(SOD)in the ischemic region of myocardial tissue in the ischemiareperfusion group was significantly decreased and malondialdehyde(MDA)marktdly increased Ca2+in myocardial cells was increased. and ultrastructural changes of myocardial tisstes were severe in the APN-pretreated ischemia-reperfusion group ,on the contrary,all the above parameters showed reversely,i,e.,SOD increased ,MDA and intracellular Ca2+ decreased.the ultrastructure changes were less distorted. 展开更多
关键词 andrographis paniculata nees (APN) myocardial ischemiareperfusion
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