期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Myofibroblastic sarcomas:a clinicopathological study of 20 cases 被引量:12
1
作者 MENG Guo-zhao ZHANG Hong-ying +5 位作者 BU Hong ZHANG Xian-liang PANG Zong-guo KE Qi LIU Xi YANG Guo 《Chinese Medical Journal》 SCIE CAS CSCD 2007年第5期363-369,共7页
Background Myofibroblastic sarcoma was used to be a controversial neoplasm. This study investigated the clinicopathological features of 20 cases of myofibroblastic sarcoma arising in different locations. Methods The p... Background Myofibroblastic sarcoma was used to be a controversial neoplasm. This study investigated the clinicopathological features of 20 cases of myofibroblastic sarcoma arising in different locations. Methods The paraffin-embedded tissue samples from 20 cases of patients with myofibroblastic sarcoma were stained immunohistochemically, and 5 cases examined by electron microscopy. Student's t test was used to analyze the difference of Ki-67 labeling index between grade 1 and grade 2 myofibroblastic sarcomas. Results Histologically, the tumors were composed of slender spindle cells with eosinophilic cytoplasm, and fusiform, tapering, wavy, or plump ovoid; vesicular nuclei and a small central eosinophUic nucleoli. Immunohistochemically, the tumor cells expressed smooth muscle actin (18/20), muscle specific actin (16/20), fibronectin (20/20) and desmin (2/20). Ultrastructurally, the tumor cells revealed abundant rough endoplasmic reticulum and longitudinally arranged fine filaments with focal densities in the cytoplasm. A clinical follow-up of 19 patients showed that 2 cases experienced local recurrence and distant metastasis 6 months to 4 years after the initial operation. Nine cases recurred locally 17 to 46 months after the initial excision, and 9 cases were alive with no evidence of disease. Conclusions Myofibroblastic sarcomas, which exhibit diverse histological appearance, can easily be misdiagnosed as benign tumors. Myofibroblastic sarcomas are local destructive lesions with frequent recurrence, and may metastase distantly. 展开更多
关键词 myofibrosarcom MYOFIBROBLAST SARCOMA IMMUNOHISTOCHEMISTRY
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部