Inflammatory myoglandular polyp causing hematochezia

A case of inflammatory myoglandular polyp (IMGP) causing hematochezia is reported. The patient was a 33-year-old man who visited our hospital for further evaluation of hematochezia. Colonoscopy revealed a red, hard, spherical peduncular polyp with erosion and mucous exudation, about 20 mm in diameter, in the descending colon. Excluding the polyp, there was no lesion in the colorectum. Endoscopic polypectomy was performed. Histological examination of the specimen revealed inflammatory granulation tissue in the lamina propria, proliferation of smooth muscle, and hyperplastic glands with variable cystic changes. This polyp was diagnosed as an IMGP. The symptom of hematochezia was resolved after endoscopic resection. Our case shows that treatment is necessary for IMGP if intestinal bleeding occurs and endoscopists should be aware of the endoscopic characteristics of IMGP.

胃平滑肌腺体错构瘤3例临床病理分析

目的 探讨胃平滑肌腺体错构瘤的临床病理特点、鉴别诊断、治疗及预后。方法 回顾性分析3例胃平滑肌腺体错构瘤的临床病理形态学特点,免疫表型,并复习相关文献。结果 3例中女性2例,男性1例;年龄44~71岁,中位年龄54岁。2例发生在胃体,1例发生在胃底。主要症状为腹部饱胀不适、腹痛。镜下肿瘤发生于黏膜及黏膜下层,由形态温和的梭形细胞与镶嵌其中的腺体组成,部分腺体扩张,间质内可见少量淋巴细胞、浆细胞浸润及组织细胞浸润。免疫标记腺上皮表达CK7、 CK 8/18和CK19,梭形细胞表达Desmin和SMA。结论 胃平滑肌腺体错构瘤为一种少见的良性肿瘤,临床仅有轻微不适症状,诊断依靠病理检查,内镜下切除为主要治疗方法,预后良好。