N-budding lipid vesicles with single holes were analyzed theoretically by taking into account the line tension of membrane with a hole and the bending energy of membranes based on the Spontaneous-Curvature (SC) model....N-budding lipid vesicles with single holes were analyzed theoretically by taking into account the line tension of membrane with a hole and the bending energy of membranes based on the Spontaneous-Curvature (SC) model. We solved numerically the Euler-Lagrange equation and the boundary conditions holding on the membrane edge to obtain axisymmetric vesicle shapes, which minimize the total energy. The numerical results show that the size of the opening-up vesicle is larger when the line tension is lower. In other words, additive protein molecules reduce the line tension of lipid membranes, such as talin dose.展开更多
基金supported by the National Natural Science Foundation of China (Grant no.10374063)
文摘N-budding lipid vesicles with single holes were analyzed theoretically by taking into account the line tension of membrane with a hole and the bending energy of membranes based on the Spontaneous-Curvature (SC) model. We solved numerically the Euler-Lagrange equation and the boundary conditions holding on the membrane edge to obtain axisymmetric vesicle shapes, which minimize the total energy. The numerical results show that the size of the opening-up vesicle is larger when the line tension is lower. In other words, additive protein molecules reduce the line tension of lipid membranes, such as talin dose.