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A Sharding Scheme Based on Graph Partitioning Algorithm for Public Blockchain
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作者 Shujiang Xu Ziye Wang +4 位作者 Lianhai Wang Miodrag J.Mihaljevi′c Shuhui Zhang Wei Shao Qizheng Wang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期3311-3327,共17页
Blockchain technology,with its attributes of decentralization,immutability,and traceability,has emerged as a powerful catalyst for enhancing traditional industries in terms of optimizing business processes.However,tra... Blockchain technology,with its attributes of decentralization,immutability,and traceability,has emerged as a powerful catalyst for enhancing traditional industries in terms of optimizing business processes.However,transaction performance and scalability has become the main challenges hindering the widespread adoption of blockchain.Due to its inability to meet the demands of high-frequency trading,blockchain cannot be adopted in many scenarios.To improve the transaction capacity,researchers have proposed some on-chain scaling technologies,including lightning networks,directed acyclic graph technology,state channels,and shardingmechanisms,inwhich sharding emerges as a potential scaling technology.Nevertheless,excessive cross-shard transactions and uneven shard workloads prevent the sharding mechanism from achieving the expected aim.This paper proposes a graphbased sharding scheme for public blockchain to efficiently balance the transaction distribution.Bymitigating crossshard transactions and evening-out workloads among shards,the scheme reduces transaction confirmation latency and enhances the transaction capacity of the blockchain.Therefore,the scheme can achieve a high-frequency transaction as well as a better blockchain scalability.Experiments results show that the scheme effectively reduces the cross-shard transaction ratio to a range of 35%-56%and significantly decreases the transaction confirmation latency to 6 s in a blockchain with no more than 25 shards. 展开更多
关键词 Blockchain sharding graph partitioning algorithm
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Hybrid Strategy of Partitioned and Monolithic Methods for Solving Strongly Coupled Analysis of Inverse and Direct Piezoelectric and Circuit Coupling
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作者 Daisuke Ishihara Syunnosuke Nozaki +1 位作者 Tomoya Niho Naoto Takayama 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第8期1371-1386,共16页
The inverse and direct piezoelectric and circuit coupling are widely observed in advanced electro-mechanical systems such as piezoelectric energy harvesters.Existing strongly coupled analysis methods based on direct n... The inverse and direct piezoelectric and circuit coupling are widely observed in advanced electro-mechanical systems such as piezoelectric energy harvesters.Existing strongly coupled analysis methods based on direct numerical modeling for this phenomenon can be classified into partitioned or monolithic formulations.Each formulation has its advantages and disadvantages,and the choice depends on the characteristics of each coupled problem.This study proposes a new option:a coupled analysis strategy that combines the best features of the existing formulations,namely,the hybrid partitioned-monolithic method.The analysis of inverse piezoelectricity and the monolithic analysis of direct piezoelectric and circuit interaction are strongly coupled using a partitioned iterative hierarchical algorithm.In a typical benchmark problem of a piezoelectric energy harvester,this research compares the results from the proposed method to those from the conventional strongly coupled partitioned iterative method,discussing the accuracy,stability,and computational cost.The proposed hybrid concept is effective for coupled multi-physics problems,including various coupling conditions. 展开更多
关键词 Structure-piezoelectric-circuit interaction energy harvesting partitioned method monolithic method hybrid method
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Restraint effect of partition wall on the tunnel floor heave in layered rock mass
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作者 YANG Yunyun HUANG Da +2 位作者 ZHONG Zhu LIU Yang PENG Jianbing 《Journal of Mountain Science》 SCIE CSCD 2024年第7期2462-2479,共18页
The presence of horizontal layered rocks in tunnel engineering significantly impacts the stability and strength of the surrounding rock mass,leading to floor heave in the tunnel.This study focused on preparing layered... The presence of horizontal layered rocks in tunnel engineering significantly impacts the stability and strength of the surrounding rock mass,leading to floor heave in the tunnel.This study focused on preparing layered specimens of rock-like material with varying thickness to investigate the failure behaviors of tunnel floors.The results indicate that thin-layered rock mass exhibits weak interlayer bonding,causing rock layers near the surface to buckle and break upwards when subjected to horizontal squeezing.With an increase in the layer thickness,a transition in failure mode occurs from upward buckling to shear failure along the plane,leading to a noticeable reduction in floor heave deformation.The primary cause of significant deformation in floor heave is upward buckling failure.To address this issue,the study proposes the installation of a partition wall in the middle of the floor to mitigate heave deformation of the rock layers.The results demonstrate that the partition wall has a considerable stabilizing effect on the floor,reducing the zone of buckling failure and minimizing floor heave deformation.It is crucial for the partition wall to be sufficiently high to prevent buckling failure and ensure stability.Through simulation calculations on an engineering example,it is confirmed that implementing a partition wall can effectively reduce floor heave and enhance the stability of tunnel floor. 展开更多
关键词 Layered rock Floor heave Horizontal compression test Failure behavior partition wall
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Algorithm Selection Method Based on Coupling Strength for Partitioned Analysis of Structure-Piezoelectric-Circuit Coupling
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作者 Daisuke Ishihara Naoto Takayama 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第2期1237-1258,共22页
In this study, we propose an algorithm selection method based on coupling strength for the partitioned analysis ofstructure-piezoelectric-circuit coupling, which includes two types of coupling or inverse and direct pi... In this study, we propose an algorithm selection method based on coupling strength for the partitioned analysis ofstructure-piezoelectric-circuit coupling, which includes two types of coupling or inverse and direct piezoelectriccoupling and direct piezoelectric and circuit coupling. In the proposed method, implicit and explicit formulationsare used for strong and weak coupling, respectively. Three feasible partitioned algorithms are generated, namely(1) a strongly coupled algorithm that uses a fully implicit formulation for both types of coupling, (2) a weaklycoupled algorithm that uses a fully explicit formulation for both types of coupling, and (3) a partially stronglycoupled and partially weakly coupled algorithm that uses an implicit formulation and an explicit formulation forthe two types of coupling, respectively.Numerical examples using a piezoelectric energy harvester,which is a typicalstructure-piezoelectric-circuit coupling problem, demonstrate that the proposed method selects the most costeffectivealgorithm. 展开更多
关键词 MULTIPHYSICS coupling strength partitioned algorithm structure-piezoelectric-circuit coupling strongly coupled algorithm weakly coupled algorithm
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Partitioning Calculation Method of Short-Circuit Current for High Proportion DG Access to Distribution Network
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作者 Wei Wang Qingzhu Shao +4 位作者 Shaoliang Wang Yiwei Zhao Yuanbo Ye Duanchao Li Mengyu Wu 《Energy Engineering》 EI 2024年第9期2569-2584,共16页
Aiming at the problemthat the traditional short-circuit current calculationmethod is not applicable to Distributed Generation(DG)accessing the distribution network,the paper proposes a short-circuit current partitioni... Aiming at the problemthat the traditional short-circuit current calculationmethod is not applicable to Distributed Generation(DG)accessing the distribution network,the paper proposes a short-circuit current partitioning calculation method considering the degree of voltage drop at the grid-connected point of DG.Firstly,the output characteristics of DG in the process of low voltage ride through are analyzed,and the equivalent output model of DG in the fault state is obtained.Secondly,by studying the network voltage distribution law after fault in distribution networks under different DG penetration rates,the degree of voltage drop at the grid-connected point of DG is used as a partition index to partition the distribution network.Then,iterative computation is performed within each partition,and data are transferred between partitions through split nodes to realize the fast partition calculation of short-circuit current for high proportion DG access to distribution network,which solves the problems of long iteration time and large calculation error of traditional short-circuit current.Finally,a 62-node real distribution network model containing a high proportion of DG access is constructed onMATLAB/Simulink,and the simulation verifies the effectiveness of the short-circuit current partitioning calculation method proposed in the paper,and its calculation speed is improved by 48.35%compared with the global iteration method. 展开更多
关键词 High proportion DG short-circuit calculation low voltage ride through partition iteration
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Understanding and simulating of three-dimensional subsurface hydrological partitioning in an alpine mountainous area, China
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作者 ZHANG Lanhui TU Jiahao +3 位作者 AN Qi LIU Yu XU Jiaxin ZHANG Haixin 《Journal of Arid Land》 SCIE CSCD 2024年第11期1463-1483,共21页
Critical zone(CZ)plays a vital role in sustaining biodiversity and humanity.However,flux quantification within CZ,particularly in terms of subsurface hydrological partitioning,remains a significant challenge.This stud... Critical zone(CZ)plays a vital role in sustaining biodiversity and humanity.However,flux quantification within CZ,particularly in terms of subsurface hydrological partitioning,remains a significant challenge.This study focused on quantifying subsurface hydrological partitioning,specifically in an alpine mountainous area,and highlighted the important role of lateral flow during this process.Precipitation was usually classified as two parts into the soil:increased soil water content(SWC)and lateral flow out of the soil pit.It was found that 65%–88%precipitation contributed to lateral flow.The second common partitioning class showed an increase in SWC caused by both precipitation and lateral flow into the soil pit.In this case,lateral flow contributed to the SWC increase ranging from 43%to 74%,which was notably larger than the SWC increase caused by precipitation.On alpine meadows,lateral flow from the soil pit occurred when the shallow soil was wetter than the field capacity.This result highlighted the need for three-dimensional simulation between soil layers in Earth system models(ESMs).During evapotranspiration process,significant differences were observed in the classification of subsurface hydrological partitioning among different vegetation types.Due to tangled and aggregated fine roots in the surface soil on alpine meadows,the majority of subsurface responses involved lateral flow,which provided 98%–100%of evapotranspiration(ET).On grassland,there was a high probability(0.87),which ET was entirely provided by lateral flow.The main reason for underestimating transpiration through soil water dynamics in previous research was the neglect of lateral root water uptake.Furthermore,there was a probability of 0.12,which ET was entirely provided by SWC decrease on grassland.In this case,there was a high probability(0.98)that soil water responses only occurred at layer 2(10–20 cm),because grass roots mainly distributed in this soil layer,and grasses often used their deep roots for water uptake during ET.To improve the estimation of soil water dynamics and ET,we established a random forest(RF)model to simulate lateral flow and then corrected the community land model(CLM).RF model demonstrated good performance and led to significant improvements in CLM simulation.These findings enhance our understanding of subsurface hydrological partitioning and emphasize the importance of considering lateral flow in ESMs and hydrological research. 展开更多
关键词 subsurface hydrological partitioning lateral flow random forest model community land model(CLM) alpine mountainous area
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Airgap-harmonic-oriented Partitioned Design Method of PMV Motor with Improved Torque Performances
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作者 Zhaopeng Wu Li Quan +3 位作者 Zixuan Xiang Deyang Fan Tengguang Wang Xiaoyong Zhu 《CES Transactions on Electrical Machines and Systems》 EI CSCD 2024年第1期43-50,共8页
Here,we introduce a partitioned design method that is oriented toward airgap harmonic for permanent magnet vernier(PMV)motors.The method proposes the utilization of airgap flux harmonics as an effective bridge between... Here,we introduce a partitioned design method that is oriented toward airgap harmonic for permanent magnet vernier(PMV)motors.The method proposes the utilization of airgap flux harmonics as an effective bridge between the torque design region and the torque performances.To illustrate the efficacy of this method,a partitioned design PMV motor is presented and compared with the initial design.Firstly,the torque design region of the rotor is artfully divided into the torque enhancement region and ripple reduction region.Meanwhile,the main harmonics that generate output torque are chosen and enhanced,optimization.Moreover,the harmonics that generate torque ripple are selected and reduced based on torque harmonics optimization.Finally,the functions of the partitioned PMV motor torque are assessed based on the finite element method.By the purposeful design of these two regions,the output torque is strengthened while torque ripple is inhibited effectively,verifying the effectiveness and reasonability of the proposed design method. 展开更多
关键词 Permanent magnet vernier(PMV)motor Airgap flux harmonic partitioned design Low torque ripple
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A Two-Layer Active Power Optimization and Coordinated Control for Regional Power Grid Partitioning to Promote Distributed Renewable Energy Consumption
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作者 Wentao Li Jiantao Liu +3 位作者 Yudun Li GuoxinMing Kaifeng Zhang Kun Yuan 《Energy Engineering》 EI 2024年第9期2479-2503,共25页
With the large-scale development and utilization of renewable energy,industrial flexible loads,as a kind of loadside resource with strong regulation ability,provide new opportunities for the research on renewable ener... With the large-scale development and utilization of renewable energy,industrial flexible loads,as a kind of loadside resource with strong regulation ability,provide new opportunities for the research on renewable energy consumption problem in power systems.This paper proposes a two-layer active power optimization model based on industrial flexible loads for power grid partitioning,aiming at improving the line over-limit problem caused by renewable energy consumption in power grids with high proportion of renewable energy,and achieving the safe,stable and economical operation of power grids.Firstly,according to the evaluation index of renewable energy consumption characteristics of line active power,the power grid is divided into several partitions,and the interzone tie lines are taken as the optimization objects.Then,on the basis of partitioning,a two-layer active power optimization model considering the power constraints of industrial flexible loads is established.The upper-layer model optimizes the planned power of the inter-zone tie lines under the constraint of the minimum peak-valley difference within a day;the lower-layer model optimizes the regional source-load dispatching plan of each resource in each partition under the constraint of theminimumoperation cost of the partition,so as to reduce the line overlimit phenomenon caused by renewable energy consumption and save the electricity cost of industrial flexible loads.Finally,through simulation experiments,it is verified that the proposed model can effectively mobilize industrial flexible loads to participate in power grid operation and improve the economic stability of power grid. 展开更多
关键词 Renewable energy consumption active power optimization power grid partitioning industrial flexible loads line over-limit
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PartitionSim:一个面向众核结构的并行模拟器 被引量:2
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作者 焦帅 徐卫志 +2 位作者 唐士斌 范东睿 孙凝晖 《计算机学报》 EI CSCD 北大核心 2011年第11期2084-2092,共9页
该文提出了一个面向众核处理器的并行模拟器:PartitionSim.PartitionSim采用了一种新颖的方法——时序分割来加速众核结构模拟.时序分割的提出基于这样的观察:在众核结构中,有些模块之间频繁交互而有的模块之间没有交互.有鉴于此,该方... 该文提出了一个面向众核处理器的并行模拟器:PartitionSim.PartitionSim采用了一种新颖的方法——时序分割来加速众核结构模拟.时序分割的提出基于这样的观察:在众核结构中,有些模块之间频繁交互而有的模块之间没有交互.有鉴于此,该方法将目标结构分割成两部分:交互部分和非交互部分.当模拟交互部分时,主机线程严格同步,维持时序精确.当模拟非交互部分时,主机线程通过异步运行,提高模拟速度,并且产生较小的时序损失.文中所述工作在一个16核的SMP机器上用PartitionSim模拟了千核规模的Godson-T众核结构.实验结果显示,PartitionSim展示出良好的加速比,达到最高25MIPS的模拟速度,时序损失平均值为0.92%. 展开更多
关键词 并行模拟 众核 Godson-T 时序分割
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An Estimate of the Enumeration Function of Multiplicative Partitions 被引量:1
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作者 曹会中 《Chinese Quarterly Journal of Mathematics》 CSCD 1992年第2期46-48,共3页
Let f(n) denote the number of multiplicative partitions of a positive intger. We prove that if n is an odd number,then f(n)≤n/15+7/5.
关键词 multiplicative partitions
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(k,k-1)-双正则图的平衡Judicious Partitions(英文)
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作者 颜娟 许宝刚 《南京师大学报(自然科学版)》 CAS CSCD 北大核心 2008年第3期24-28,共5页
Bollobás和Scott提出猜想:任意一个边数为m且最小度大于1的图存在顶点集的平衡二部划分使得每一部分点集的导出子图包含的边数不超过m/3.Bollobás和Scott证明了绝大部分正则图存在顶点集的平衡二部划分使得每一部分点集的导... Bollobás和Scott提出猜想:任意一个边数为m且最小度大于1的图存在顶点集的平衡二部划分使得每一部分点集的导出子图包含的边数不超过m/3.Bollobás和Scott证明了绝大部分正则图存在顶点集的平衡二部划分使得每一部分点集的导出子图包含的边数比m/4小.这里讨论(k,k-1)-双正则图的平衡二部划分,证明了每一个(k,k-1)-双正则图存在平衡二部划分使得每一部分点集的导出子图包含的边数是m/4左右. 展开更多
关键词 judicious partitION 平衡二部划分 (k k-1)-双正则图
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SYNCHRONIZATION OF CHAOTIC SYSTEMS VIA LINEAR PARTITIONS
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作者 Lu Hongtao He Zhenya (Southeast University, Nanjing 210096) 《Journal of Electronics(China)》 1997年第1期27-33,共7页
In this paper, a new method for synchronization of chaotic systems is proposed. The method is based on the linear partitions of the chaotic system under consideration. A chaotic system is partitioned into a linear par... In this paper, a new method for synchronization of chaotic systems is proposed. The method is based on the linear partitions of the chaotic system under consideration. A chaotic system is partitioned into a linear part and a nonlinear part. Under some assumptions, another chaotic system which can synchronize with the original one can be contructed. The proposed method is easier to verify and more general than the conventional one in some sense. 展开更多
关键词 CHAOS SYNCHRONIZATION LINEAR partitION
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Singly Covered Minimal Elements of Linked Partitions and Cycles of Permutations
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作者 Guo Wen-kui Niu Fei-fei Du Xian-kun 《Communications in Mathematical Research》 CSCD 2019年第1期75-80,共6页
Linked partitions were introduced by Dykema(Dykema K J. Multilinear function series and transforms in free probability theory. Adv. Math., 2005, 208(1):351–407) in the study of the unsymmetrized T-transform in free p... Linked partitions were introduced by Dykema(Dykema K J. Multilinear function series and transforms in free probability theory. Adv. Math., 2005, 208(1):351–407) in the study of the unsymmetrized T-transform in free probability theory.Permutation is one of the most classical combinatorial structures. According to the linear representation of linked partitions, Chen et al.(Chen W Y C, Wu S Y J, Yan C H. Linked partitions and linked cycles. European J. Combin., 2008, 29(6): 1408–1426) de?ned the concept of singly covered minimal elements. Let L(n, k) denote the set of linked partitions of [n] with k singly covered minimal elements and let P(n, k) denote the set of permutations of [n] with k cycles. In this paper, we mainly establish two bijections between L(n, k) and P(n, k). The two bijections from a different perspective show the one-to-one correspondence between the singly covered minimal elements in L(n, k) and the cycles in P(n, k). 展开更多
关键词 singly COVERED MINIMAL element linked partitION PERMUTATION cycle
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Bijections between Lattice Paths and Plane Partitions
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作者 Mateus Alegri Eduardo Henrique de Mattos Brietzke +1 位作者 José Plínio de Oliveira Santos Robson da Silva 《Open Journal of Discrete Mathematics》 2011年第3期108-115,共8页
By using lattice paths in the three-dimensional space we obtain bijectively an interpretation for the overpartitions of a positive integer n in terms of a set of plane partitions of n . We also exhibit two bijections ... By using lattice paths in the three-dimensional space we obtain bijectively an interpretation for the overpartitions of a positive integer n in terms of a set of plane partitions of n . We also exhibit two bijections between unrestricted partitions of n and different subsets of plane partitions of n . 展开更多
关键词 LATTICE PATHS PLANE partitions partitions q-Analog.
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Root-Patterns to Algebrising Partitions
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作者 Rex L. Agacy 《Advances in Pure Mathematics》 2015年第1期31-41,共11页
The study of the confluences of the roots of a given set of polynomials—root-pattern problem— does not appear to have been considered. We examine the situation, which leads us on to Young tableaux and tableaux repre... The study of the confluences of the roots of a given set of polynomials—root-pattern problem— does not appear to have been considered. We examine the situation, which leads us on to Young tableaux and tableaux representations. This in turn is found to be an aspect of multipartite partitions. We discover, and show, that partitions can be expressed algebraically and can be “differentiated” and “integrated”. We show a complete set of bipartite and tripartite partitions, indicating equivalences for the root-pattern problem, for select pairs and triples. Tables enumerating the number of bipartite and tripartite partitions, for small pairs and triples are given in an appendix. 展开更多
关键词 COMBINATORICS partitions Polynomials Root-Patterns TABLEAUX
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A New Formula for Partitions in a Set of Entities into Empty and Nonempty Subsets, and Its Application to Stochastic and Agent-Based Computational Models
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作者 Ghennadii Gubceac Roman Gutu Florentin Paladi 《Applied Mathematics》 2013年第10期14-21,共8页
In combinatorics, a Stirling number of the second kind S (n,k)? is the number of ways to partition a set of n objects into k nonempty subsets. The empty subsets are also added in the models presented in the article in... In combinatorics, a Stirling number of the second kind S (n,k)? is the number of ways to partition a set of n objects into k nonempty subsets. The empty subsets are also added in the models presented in the article in order to describe properly the absence of the corresponding type i of state in the system, i.e. when its “share” Pi =0?. Accordingly, a new equation for partitions P (N, m)? in a set of entities into both empty and nonempty subsets was derived. The indistinguishableness of particles (N identical atoms or molecules) makes only sense within a cluster (subset) with the size?0≤ni ≥N. The first-order phase transition is indeed the case of transitions, for example in the simplest interpretation, from completely liquid state?typeL = {n1 =N, n2 = 0} to the completely crystalline state??typeC= {n1 =0, n2 = N }. These partitions are well distinguished from the physical point of view, so they are ‘typed’ differently in the model. Finally, the present developments in the physics of complex systems, in particular the structural relaxation of super-cooled liquids and glasses, are discussed by using such stochastic cluster-based models. 展开更多
关键词 partitions AGENT-BASED Models STOCHASTIC Processes Complex Systems
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The Fractal and the Recurrence Equations Concerning the Integer Partitions
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作者 Meng Zhang 《Advances in Pure Mathematics》 2018年第6期624-630,共7页
This paper introduced a way of fractal to solve the problem of taking count of the integer partitions, furthermore, using the method in this paper some recurrence equations concerning the integer partitions can be ded... This paper introduced a way of fractal to solve the problem of taking count of the integer partitions, furthermore, using the method in this paper some recurrence equations concerning the integer partitions can be deduced, including the pentagonal number theorem. 展开更多
关键词 FRACTAL INTEGER partitION Pentagonal Number THEOREM RECURRENCE EQUATIONS
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A Study on Associated Rules and Fuzzy Partitions for Classification
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作者 Yeu-Shiang Huang Jyi-Feng Yao 《Intelligent Information Management》 2012年第5期217-224,共8页
The amount of data for decision making has increased tremendously in the age of the digital economy. Decision makers who fail to proficiently manipulate the data produced may make incorrect decisions and therefore har... The amount of data for decision making has increased tremendously in the age of the digital economy. Decision makers who fail to proficiently manipulate the data produced may make incorrect decisions and therefore harm their business. Thus, the task of extracting and classifying the useful information efficiently and effectively from huge amounts of computational data is of special importance. In this paper, we consider that the attributes of data could be both crisp and fuzzy. By examining the suitable partial data, segments with different classes are formed, then a multithreaded computation is performed to generate crisp rules (if possible), and finally, the fuzzy partition technique is employed to deal with the fuzzy attributes for classification. The rules generated in classifying the overall data can be used to gain more knowledge from the data collected. 展开更多
关键词 Data Mining Fuzzy partitION PARTIAL CLASSIFICATION ASSOCIATION RULE Knowledge Discovery.
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Cytotoxic Effect of Methanol Extracts and Partitions of Two Mexican Desert Plants against the Murine Lymphoma L5178Y-R
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作者 Ramiro Quintanilla-Licea Ricardo Gomez-Flores +3 位作者 Mario Ángel Samaniego-Escamilla Humberto Carlos Hernández-Martínez Patricia Tamez-Guerra Rolando Morado-Castillo 《American Journal of Plant Sciences》 2016年第11期1521-1530,共11页
Pachycereus marginatus (DC.) Britton & Rose and Ibervillea sonorae (S. Watson) Greene have been used in the Mexican traditional medicine for the treatment of various diseases, including cancer. The present study a... Pachycereus marginatus (DC.) Britton & Rose and Ibervillea sonorae (S. Watson) Greene have been used in the Mexican traditional medicine for the treatment of various diseases, including cancer. The present study aims to investigate the cytotoxic activity of these plants against a murine lymphoma. Soxhlet extraction of dried and powdered plant material was performed with methanol. Also, a further partitioning of these methanolic extracts with hexane and ethyl acetate was achieved. The in vitro cytotoxic activity against the murine lymphoma L5178Y-R cell line was assessed via the colorimetric MTT assay. The methanol extract from P. marginatus exhibited high cytotoxic activity (up to 94%) at concentrations ranging from 3.9 to 500 μg/mL;however, hexane and ethyl acetate partitions from this methanolic extract showed lower but significant (p < 0.05) concentration-dependent cytotoxicity (hexane partition up to 94% at 500 μg/mL;ethyl acetate partition up to 94% at 65.5 μg/mL). The methanolic extract and partitions derived from I. sonorae also showed significant (p < 0.05) and concentration-dependent cytotoxicity against L5178Y-R cells at concentrations ranging from 7.81 to 500 μg/mL (methanolic extract up to 63% at 500 μg/mL;hexane partition up to 76% at 250 μg/mL;ethyl acetate partition up to 73% at 500 μg/mL). These results demonstrate that the methanol extracts and partitions from P. marginatus and I. sonorae possess significant cytotoxic activity against the murine lymphoma L5178Y-R and validate the ethnobotanical use of these plants for the treatment of diseases consistent with cancer symptomatology. Previous scientific reports describe the isolation of isoquinoline alkaloids of P. marginatus as well as cucurbitacins from I. sonorae, phytochemicals that could be responsible for their observed cytotoxic activity in this research. The direct extraction with methanol of medicinal plants allows extracting of both high and low-polarity compounds, contrary to the simple extraction with water that only allows obtaining compounds of high polarity. The subsequent partition of the methanol extract with a solvent of low polarity (hexane) and another of medium polarity (ethyl acetate) allows making a preliminary fractionation of the bioactive molecules present in the plant that will facilitate the bioguided chromatographic isolation of the pure compounds responsible for the biological activity of the plant. 展开更多
关键词 Anticancer Plants CACTACEAE CUCURBITACEAE Mexican Medicinal Plants Extracts partitions
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2D Minimum Compliance Topology Optimization Based on a Region Partitioning Strategy 被引量:1
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作者 Chong Wang Tongxing Zuo +3 位作者 Haitao Han Qianglong Wang Han Zhang Zhenyu Liu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第7期655-683,共29页
This paper presents an extended sequential element rejection and admission(SERA)topology optimizationmethod with a region partitioning strategy.Based on the partitioning of a design domain into solid regions and weak ... This paper presents an extended sequential element rejection and admission(SERA)topology optimizationmethod with a region partitioning strategy.Based on the partitioning of a design domain into solid regions and weak regions,the proposed optimizationmethod sequentially implements finite element analysis(FEA)in these regions.After standard FEA in the solid regions,the boundary displacement of the weak regions is constrained using the numerical solution of the solid regions as Dirichlet boundary conditions.This treatment can alleviate the negative effect of the material interpolation model of the topology optimization method in the weak regions,such as the condition number of the structural global stiffness matrix.For optimization,in which the forward problem requires nonlinear structural analysis,a linear solver can be applied in weak regions to avoid numerical singularities caused by the over-deformedmesh.To enhance the robustness of the proposedmethod,the nonmanifold point and island are identified and handled separately.The performance of the proposed method is verified by three 2D minimum compliance examples. 展开更多
关键词 Topology optimization region partition nonmanifold point matrix conditional number geometric nonlinearity
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