The different investigation has been carried out on the biological activities of titanium dioxide nanoparticle but the effect of this nano product on the antibacterial activity of different antibiotics has not been ye...The different investigation has been carried out on the biological activities of titanium dioxide nanoparticle but the effect of this nano product on the antibacterial activity of different antibiotics has not been yet demonstrated. In this study the nano size TiO2 is synthesized using citric acid and alpha dextrose and the enhancement effect of TiO2 nanoparticle on the antibacterial activity of different antibiotics was evaluated against Methicillin-resistant Staphylococcus aureus (MRSA). During the present study, different concentrations of nano-scale TiO2 were tested to find out the best concentration that can have the most effective antibacterial property against the MRSA culture. Disk diffusion method was used to determine the antibacterial activity of these antibiotics in the absence and presence of sub inhibitory concentration of TiO2 nano particle. A clinical isolate of MRSA, isolated from Intensive Care Unit (ICU) was used as test strain. In the presence of sub-inhibitory concentration of TiO2 nanoparticle (20 μg/disc) the antibacterial activities of all antibiotics have been increased against test strain with minimum 2 mm to maximum 10mm. The highest increase in inhibitory zone for MRSA was observed against pencillin G and amikacin (each 10 mm). Conversely, in case of nalidixic acid, TiO2 nanoparticle showed a Synergic effect on the antibacterial activity of this antibiotic against test strain. These results signify that the TiO2 nanoparticle potentate the antimicrobial action of beta lactums, cephalosporins, aminoglycosides, glycopeptides, macrolids and lincosamides, tetracycline a possible utilization of nano compound in combination effect against MRSA.展开更多
The biodiesel prepared from Xanthoceras Sorbiflia Bunge Oil catalyzed by Ce doped nano PO_4^(3-)/ZrO_2 was investigated. A maximum biodiesel yield of 91.83% was achieved at the concentration of Ce^(3+) up to 0.1 mol/L...The biodiesel prepared from Xanthoceras Sorbiflia Bunge Oil catalyzed by Ce doped nano PO_4^(3-)/ZrO_2 was investigated. A maximum biodiesel yield of 91.83% was achieved at the concentration of Ce^(3+) up to 0.1 mol/L, calcination temperature 500 °C, calcination time 3.0 h, and the concentration of phosphoric acid of 3.5 mol/L. Ce-nano PO_4^(3-)/ZrO_2 catalyst activities were correlated with the observed physico-chemical characteristics derived from scanning electron microscopy(SEM), FT-infrared(FT-IR), X-ray diffraction(XRD), thermogravimetric(TG) and Brunauer-Emmett-Teller(BET) analysis. The delayed crystallization of ZrO_2 made surface oxides have more defects which were beneficial to the adsorption of PO_4^(3-) by the concentration increment of Ce^(3+). The chemical composition of synthesized biodiesel was confirmed by gas chromatography(GC). The characteristics of Xanthoceras Sorbiflia Bunge oil were found within the optimal range in accordance with Chinese No. 0 diesel standard as a substitute diesel fuel.展开更多
文摘The different investigation has been carried out on the biological activities of titanium dioxide nanoparticle but the effect of this nano product on the antibacterial activity of different antibiotics has not been yet demonstrated. In this study the nano size TiO2 is synthesized using citric acid and alpha dextrose and the enhancement effect of TiO2 nanoparticle on the antibacterial activity of different antibiotics was evaluated against Methicillin-resistant Staphylococcus aureus (MRSA). During the present study, different concentrations of nano-scale TiO2 were tested to find out the best concentration that can have the most effective antibacterial property against the MRSA culture. Disk diffusion method was used to determine the antibacterial activity of these antibiotics in the absence and presence of sub inhibitory concentration of TiO2 nano particle. A clinical isolate of MRSA, isolated from Intensive Care Unit (ICU) was used as test strain. In the presence of sub-inhibitory concentration of TiO2 nanoparticle (20 μg/disc) the antibacterial activities of all antibiotics have been increased against test strain with minimum 2 mm to maximum 10mm. The highest increase in inhibitory zone for MRSA was observed against pencillin G and amikacin (each 10 mm). Conversely, in case of nalidixic acid, TiO2 nanoparticle showed a Synergic effect on the antibacterial activity of this antibiotic against test strain. These results signify that the TiO2 nanoparticle potentate the antimicrobial action of beta lactums, cephalosporins, aminoglycosides, glycopeptides, macrolids and lincosamides, tetracycline a possible utilization of nano compound in combination effect against MRSA.
基金Supported by Key Laboratory of Bio-based Material Science&Technology(Northeast Forestry University)Ministry of Education(No.SWZCL2016-10)+2 种基金Natural Science Foundation of Inner Mongolia(No.2018BS03004)Talent Development Fund of Inner MongoliaNational Majority R&D Program of China(2017YFD06002025)
文摘The biodiesel prepared from Xanthoceras Sorbiflia Bunge Oil catalyzed by Ce doped nano PO_4^(3-)/ZrO_2 was investigated. A maximum biodiesel yield of 91.83% was achieved at the concentration of Ce^(3+) up to 0.1 mol/L, calcination temperature 500 °C, calcination time 3.0 h, and the concentration of phosphoric acid of 3.5 mol/L. Ce-nano PO_4^(3-)/ZrO_2 catalyst activities were correlated with the observed physico-chemical characteristics derived from scanning electron microscopy(SEM), FT-infrared(FT-IR), X-ray diffraction(XRD), thermogravimetric(TG) and Brunauer-Emmett-Teller(BET) analysis. The delayed crystallization of ZrO_2 made surface oxides have more defects which were beneficial to the adsorption of PO_4^(3-) by the concentration increment of Ce^(3+). The chemical composition of synthesized biodiesel was confirmed by gas chromatography(GC). The characteristics of Xanthoceras Sorbiflia Bunge oil were found within the optimal range in accordance with Chinese No. 0 diesel standard as a substitute diesel fuel.
