Preparation and Characterization of Cu-Ag-inorganic Antibacterial Material Containing Rare Earths

Inorganic antibacterial materials consist of the antibacterial ions, the additives and the carrier. In this study, we synthesized a new inorganic antibacterialmaterial, of which Cu2+ and Ag+ were selected to be the bi-component antibacterial ions, cerous nitrate served as the additives, and the white carbon black was chosen as the carrier, which was prepared by a sol-gel method. The as-synthesized antibacterial material was characterized by inductively coupled plasma, particle size measurement instrument, scanning electron microscope and enumeration tests. The result showed that the amount of antibacterial ions and bacteriostasis rate of this new material are higher than those for the single-ion inorganic antibacterial material. In addition, the particle size of this material can be extended down to 7 μm with a narrow size distribution. Other advantages of this material are its loose and dispersive structure, good thermal and light stability. From the antibacterial experiment in rubber and the coating surface of metal, this new material showed promising results. The possible antibacterial mechanism was also proposed through all the experimental data in this study.

Prediction Model of Antibacterial Activities for Inorganic Antibacterial Agents Based on Artificial Neural Networks

Quantitatively evaluation of antibacterial activities of inorganic antibacterial agents is an urgent problem to be solved. Using experimental data by an orthogonal design, a prediction model of the relation between conditions of preparing inorganic antibacterial agents and their antibacterial activities has been developed. This is accomplished by introducing BP artificial neural networks in the study of inorganic antibacterial agents. It provides a theoretical support for the development and research on inorganic antibacterial agents. Key words inorganic antibacterial agent - antibacterial activity - neural networks - nanometer material

Silver Supported on White Carbon Black Containing Rare Earths as Antibacterial Material

The antimicrobial effect of the Ag-White Carbon Black containing rare earth was investigated. Inorganic antibiotic materials consist of the antibacterial ion, the additive and the carrier. The sol-gel method was used to prepare the white carbon black carrier. Ag+ was selected to be the antibacterial ion, and cerous nitrate was selected to be the additive. They were synthesized on the white carbon black carrier. The structures and properties of antibacterial material were characterized by inductively coupled plasma, particle size measurement instrument, fourier transform infrared and enumeration tests (Escherichia coli as experimental bacterium). Results showed that the amount of antibacterial ions and bacteriostasis rate of this new material are higher than those for the general Ag-antibacterial white carbon black (without containing rare earth). Ag+ was bound to white carbon black by ion exchange process and adsorption process. Bacteriostasis rate is over 99%, and the particle size can be extended down to 7 μm with a narrow size distribution. Other advantages of this material are good thermal and light stability. Furthermore, from the antibacterial experiment in rubber and the coating surface of metal, this new material showed promising results. The possible antibacterial mechanism was also proposed through all the experimental data in this study.

The Self-assembling and Application of Inorganic Anti-bacterial Material Made of Natural Nanoporous Carrier

The inorganic antimicrobial material was inhibited to the microbes with the added metal ion,Zn.The primary wet product carrying 5%-10% zinc ion was generated under the following conditions：temperature was 95 ℃,solution zinc concentration was 1.2-2.0 mol/L,and the ratio of Zn solution to zeolite weight was 5：1.The final stable product was manufactured after baking in an oven for 1-3 h at the temperature of 500-900 ℃.The baked material was tested for its disinfection effectiveness and coloring effect when mixed with paint coating.Based on the final batch of tests,the zinc content of this anti-microbial product was further optimized.

Optimized preparation of zinc-inorganic antibacterial material containing samarium using response surface methodology

A Box-Behnken design （BBD） of response surface methodology （RSM） was used to optimize the preparation of the Zn-Sm antibacterial white carbon black by the sol-gel method. The statistical analysis of the results showed that the particle size of the Zn-Sm antibacterial white carbon black was significantly affected by the reaction time, reaction temperature and the stirring speed. According to analysis of variance （ANOVA）, the values of the determination coefficient （R2=0.9821） and the ＂Pred R-Squared＂ of 0.8227 were in reasonable agreement with the ＂Adj R-Squared＂ of 0.9591. It was indicated that this model could be used to navigate the design space. The optimized reaction time, temperature and the stirring speed were 0.88 h, 87.83 ℃, and 473.45 r/rain, respectively. In addition, the bacteriostasis rate of the product was about 97.92%.

Synthesis,characterization,and antimicrobial properties of Cu-inorganic antibacterial material containing lanthanum

In this paper a kind of new inorganic antibacterial material:Cu-antibacterial white carbon black containing lanthanum was synthesized.The characterization and antimicrobial effect of the Cu-antibacterial white carbon black containing lanthanum was investigated.Inorganic antibiotic materials comprised the carrier,the antibacterial ion and the additive.In this study,we choosed white carbon black as the carrier,which was compound by a sol-gel method.Copper ion was selected to be the antibacterial ion,and lanthanum nitrate was selected to be the additive.The as-synthesized Cu-La-antibacterial white carbon black was characterized by inductively coupled plasma(ICP),laser particle size analyzer,Fourier transform infra-red spectroscopy(FT-IR) and antibacterial activity test(Escherichia coli as experimental bacterium).Results showed that the amount of antibacterial ions of the Cu-La-antibacterial white carbon black was higher than that for the general Cu-antibacterial white carbon black.Its bacteriostasis rate was about 98%(when the content of Cu2+ was about 3%),and corresponded to Ag-antibacterial white carbon black(99%).The particle size of Cu-La-antibacterial white carbon black was under 30 μm with a narrow size distribution.Copper ion was bound to white carbon black by ion exchange process.Moreover,this new inorganic antibacterial material showed promising result on the coating surface of metal.

空气微生物净化材料研究进展

空气微生物的污染会导致多种疾病的发生,其中致病性微生物严重影响了人体健康和环境保护,常见抑制方法无法满足复杂的需求和环境。新型抗菌材料的出现不仅弥补了常见抑制方法的缺陷,而且因其独特的抗菌机理和持续的抗菌效果,被广泛应用于空气微生物的净化及控制。本文归纳了常见抑制方法的缺陷,并将新型抗菌材料分为无机抗菌材料、有机抗菌材料、复合抗菌材料和光催化材料,阐述其在空气微生物净化领域的研究现状。

具有抗菌性能骨组织修复材料研究进展

开放性骨折、关节炎(OA)和骨质疏松(OP)等疾病所导致的骨缺损修复术后抗感染已成为临床治疗上的一个难题。骨科围手术期大量应用抗生素易导致细菌耐药并加重患者的经济负担,因此开发非抗生素途径的抗菌骨修复材料是国内外众多科学家的追求与愿景。目前,非负载抗生素的骨修复材料主要有复合无机抗菌剂、复合有机抗菌剂和仿生纳米结构表面抗菌剂三类。现从抗菌作用、生物相容性和各自优缺点对上述三类骨修复材料进行综述,以期为开发新型具有抗菌和成骨作用的多功能骨修复材料提供新思路。

强力安全的无机抗菌功能材料

通过对无机抗菌材料的载体、抗菌金属离子及制备工艺的研究，获得了抗菌率高且又安全的系列无机抗菌材料，其中有能耐１３５０℃高温的无机抗菌材料．试验表明，该无机抗菌材料对大肠杆菌、黄色葡萄球菌的最小抑菌浓度ＭＩＣ值均为７５ｐｐｍ，对大、小白鼠的急性经口毒性的 ＬＤ５０＞１００００ｍｇ／ｋｇ，亚急性毒性试验的无异常、无作用的量为 １００ｍｇ／ｋｇ·ｄ．

银系无机抗菌材料研究进展

系统论述了国内外银系无机抗菌材料的研究和应用现状,重点介绍了纳米银颗粒和载银型两类无机抗菌材料,包括它们的种类、制备方法、抗菌机理及其在各种制品中的应用等。纳米银无机抗菌材料制备方法主要有物理法、化学法和生物法,载银型无机抗菌材料根据载体不同分为沸石、蒙脱石、可溶性玻璃、羟基磷灰石和磷酸盐等类型。银系无机抗菌材料在医疗用品、陶瓷、塑料、涂料等制品上已得到大量应用,但其潜在毒性和生物安全性还有待进一步关注。最后提出了银系无机抗菌材料还需深入研究的问题和今后的发展前景。

新型无机抗菌材料:载铜蒙脱石及其抗菌机理讨论

以内蒙赤峰蒙脱石为原料合成了载铜蒙脱石,它对革兰氏阴性菌E.coli和革兰氏阳性菌S.faecalis均有很强的抑止和杀灭作用,其抗菌能力大大优于载铜沸石,蒙脱石在载铜反应后矿物表面带有剩余正电荷,它的抗菌能力来自两方面因素,一方面是矿物对带相反电荷的细菌的吸附作用,另一方面是矿物释放出的铜离子对细茵的杀灭作用,这是载铜蒙脱石抗菌能力优于载铜沸石的本质原因。

无机抗菌剂的研究进展

介绍了国内外无机抗菌剂的研究发展现状,重点讨论了各种无机抗菌剂的结构特点以及抗菌机理,阐述了无机抗菌剂在现实生活中纤维制品、塑料、涂料、卫生陶瓷等方面的应用,最后指出了无机抗菌剂存在的问题,预计了将来的一些发展趋势。

稀土复合磷酸盐无机抗菌材料对陶瓷活化水性能的影响

将稀土复合磷酸盐无机抗菌材料添加到陶瓷釉浆中制备具有活化水功能的抗菌陶瓷制品。用核磁共振技术(NMR)以及溶解氧测试技术研究添加稀土复合磷酸盐无机抗菌材料对陶瓷活化水性能影响机制,以及活化水功能陶瓷制品对植物种子发芽性能的影响。结果表明:添加稀土复合磷酸盐无机抗菌材料制备的抗菌陶瓷制品可使自来水的17O NMR半峰宽由115 36Hz降低到99 15Hz;提高水中溶氧量20%;蚕豆和花生种子4天发芽率可分别提高12 5%和7 5%。稀土复合磷酸盐无机抗菌材料具有增加陶瓷制品活化自来水性能、降低水分子缔合度,促进植物种子发芽的功能。

TiO_2/Ag纳米抗菌材料

以工业级普通二氧化钛和硝酸银为原料,经溶解、净化及沉淀等过程制备了TiO2/Ag系纳米复合抗菌材料。抗菌检验表明,该抗菌材料浓度100mg·L-1,作用60min,对大肠杆菌、金黄色葡萄球菌和白色念珠菌的抑杀率均可达99.0%以上,同时,表明该抗菌材料具有良好的抗菌持久性。

无机抗菌剂的研究现状及发展趋势

介绍了无机抗菌剂的研究发展现状 ,评述了各种无机抗菌剂的结构特点及缓释抗菌机理 ,介绍了无机抗菌剂在塑料、卫生陶瓷、纤维制品等方面的应用。同时指出了无机抗菌剂存在的问题及发展趋势。

抗菌剂及抗菌材料的发展和应用

综述了近年来抗菌剂在国内外的研究开发及抗菌材料的应用发展状况 ,探讨了抗菌剂在今后几年内的发展方向 ,指出国内抗菌剂在发展中需要注意的问题。

抗菌日用瓷的研制及性能评价

抗菌制品是目前高新技术研究和开发的热点之一。本文采用自制的超细新型无机抗菌材料 ,通过研究探索制备出了具有良好抗菌效果的抗菌日用瓷制品 ,在探讨了各种因素对抗菌性能影响的基础上 。

纳米Ce/TiO_2无机抗菌剂的制备及其性能评价

以纳米锐钛矿型TiO2粉体和硝酸铈为原料,采用浸渍法制备了纳米Ce/TiO2无机抗菌剂,运用抑菌圈法对其抗菌性能进行了评价,并对其抗菌机理进行了探讨.结果表明,制备得到的纳米Ce/TiO2无机抗菌剂在黑暗中具有优异的抗菌性能,其抗菌机理为稀土元素铈离子溶出抗菌.

铜、银双组分无机抗菌材料的制备和性能研究

采用溶胶-凝胶法制取白炭黑载体,在一定条件下,将具有杀菌性能的Cu2+、Ag+附着在白炭黑载体上,制得含Cu2+、Ag+双组分杀菌活性成分的无机粉体抗菌材料。运用ICP、粒度分布仪和FTIR等手段对材料中抗菌离子含量、粒度以及抗菌离子与载体的结合方式等进行了表征。并利用菌落计数法对材料的抗菌性能进行研究。结果表明,Cu-Ag双组分抗菌白炭黑中,抗菌离子含量高于单组分抗菌白炭黑;其中,Cu2+是通过离子交换方式结合到白炭黑上的,而Ag+是通过离子交换和吸附两种方式结合到白炭黑上;材料的杀菌率达99%以上;粒径<7μm且均一。

三氯生/SiO_2杂化材料的制备和抗菌性能

以正硅酸乙酯、三氯生和γ-氨丙基三乙氧基硅烷(KH-550)为原料,制备了缓释型有机/无机复合抗菌材料。采用低温氮吸附、SEM、FTIR等手段表征了样品的比表面积、颗粒形貌和表面基团;通过摇床溶出实验检测了该复合材料的耐溶出性能;通过抑菌圈实验表征了样品的溶出抗菌性。研究发现,该方法所制备的有机/无机复合抗菌材料具有良好缓释性能,当添加KH-550时材料的耐溶出性提高。