Use Areas of Nanotechnology in Veterinary Medicine

Nanotechnology is briefly a science field searching substances having superior properties at nano-scale (different optical, mechanical and thermal properties) and those to be potentially produced in the future from these substances. Accordingly, it is a technology regarding opportunities providing the development during the formation of new products not applicable in advance and the formation of new processes. This technology that has the potential of affecting the world economy is at the development stage just now and it is thought that it will cause high changes in human life in the future 15-20 years. Nanotechnology provides an opportunity bringing new technological developments and applications appeared as impossible before as well as bringing a new perspective for available technological processes. In the context of the report in the light of mentioned information, brief information was given on the place and use of nanotechnology in fields such as systems of drug delivery, diagnosis of diseases, vaccine development, treatment of diseases, improvement of fertility functions of animals, determination of fertility capabilities of animals, store of gametes and embryos by freezing, animal breeding, farm medicine, meat and meat production, food safety, and neutralization of animals as use areas in veterinary medicine. Furthermore, in our country and the world, knowledge regarding the intended use of nano-technology based drugs used in veterinary medicine was presented in Table 1.

Crosstalk between nano/micro particulate technologies and Chinese medicine: a bibliometric analysis

Background:Chinese medicine is widely applied in Asian and Western countries for its outstanding therapeutic effect,but there are still unsolved problems such as unclear active ingredients and pharmacological effects.The application of nano/microparticle technology in Chinese medicine may become a promising strategy to solve this problem in the near future(provided that more efforts are made to in-depth exploration).In this work,a comprehensive analysis of the field was carried out from a bibliometrics perspective,and further the publishing trends and research hotspots were figured out.Methods:The articles or reviews from 2000 to 2020 were retrieved in the database of Web of Science Core Collection.The documents were processed by Clarivate Analytic,Visualization of Similarities viewer,Statistical Analysis Toolkit for Informetrics and bibliometric online platform,and the data were visualized.Finally,a bibliometric summary,citation analysis results and research trends were described.Results:A bibliometric analysis of 773 articles of interest showed that research in this field had continued to grow in recent years,with a high degree of interdisciplinary integration.Secondly,this field attached great importance to the quantitative analysis of Chinese medicine combined with nano/micro particle technology.Chinese medicine,nanoparticles and liposomes were the most accessed keywords.China was the main contributing country,and the top-10 contributing organizations were all located in China.Co-authorship was a common phenomenon in this field.Conclusion:The published literature on the application of nano/micro particle technology in Chinese medicine was summarized.The results suggested that bibliometric analysis could predict possible directions for future research in this field.

Nanotechnology and bio-functionalisation for peripheral nerve regeneration

There is a high clinical demand for new smart biomaterials, which stimulate neuronal cell proliferation, migration and increase cell-material interaction to facilitate nerve regeneration across these critical-sized defects. This article briefly reviews several up-to-date published studies using Arginine-Glycine-Aspartic acid peptide sequence, nanocomposite based on polyhedral oligomeric silsesquioxane nanoparticle and nanofibrous scaffolds as promising strategies to enhance peripheral nerve regeneration by influencing cellular behaviour such as attachment, spreading and proliferation. The aim is to establish the potent manipulations, which are simple and easy to employ in the clinical conditions for nerve regeneration and repair.

Nanotechnological approaches in diabetes treatment: A new horizon

Diabetes is a chronic metabolic disorder that affects millions of people worldwide and takes a heavy toll on human life. Treatment of diabetics often poses a problem in selection of the proper drug, its dose and unwanted side effects. Therefore, newer drugs with the least side effects but with highest efficiency are being relentlessly searched for. In recent years, nanotechnology has given new hope for the formulation of various drugs against a myriad of diseases, including diabetes. This review tries to give an overview of the advantages of various new drugs being used, including a wide range of nanoformulations of orthodox as well complementary and alternative medicines. Several studies and research reports based on nanotechnological approaches in the formulation of anti-diabetic drugs have pointed out the fact that research in the formulation of nanodrugs improved strategies for combating diabetes based on the plausible molecular mechanism of action of the drugs. Furthermore, attempts have also been made to delineate the optimum drug concentration and time of exposure in order to recommend a scientifically validated drug dose response in developing different therapeutic strategies. Thus, to a considerable extent, recent studies have contributed towards improving thelife expectancy and quality of life of diabetics, through both targeted orthodox medicine and complementary medicine, particularly those obtained from natural resources.

An Overview of Nanoparticles from Medicinal Plants: Synthesis, Characterization and Bio-Applications

Presenting and definition the most important points about nanoparticles for medicinal plants and the most important vital applications of them. The scoping review was performed according to systemic style. The research articles included the selected studies dealing with primary information on nanotechnology and medicinal plants published between 2000 and 2023. The search was at grassroots platforms such as Web of Science and PubMed. Many studies correlated the properties of plants’ nanoparticles such as stability, surface area, and high reactivity, and their small size. It was found that nanoparticles (NPs) have size ranging from some nanometers to 100 nm and their morphology is controlled because of their tiny size, NPs have a big surface area, which makes them suitable for many applications. Green nanotechnology has the potential to become an industry with very high green credentials as it is increasingly commercialized. In general, nanoparticles derived from medicinal plants offer a promising avenue for various bio-applications. Their green synthesis, biocompatibility, and potential therapeutic properties make them an attractive area of research with the potential to impact fields ranging from medicine to agriculture.

铜绿假单胞菌耐药机制及治疗技术研究新进展

铜绿假单胞菌(PA)是最常见的条件致病菌之一,严重危害人类的健康。随着广谱抗生素的大量应用,导致多重耐药菌株的出现,从而使治疗更加棘手。研究发现,免疫力低下的人群容易诱发PA的感染,随着临床耐药PA检出率的增加及抗生素的治疗效果减弱,部分患者的生活质量及预后受到很大影响。PA的感染难以控制的原因是复杂的耐药机制,其中包括生物膜的形成、孔蛋白的介导作用、外排泵以及抗菌灭活酶的产生等。由于抗生素的应用不能有效控制PA的感染,所以针对耐药机制在药物治疗方面进行研究,其中包括外排泵抑制剂、抗生素佐剂、相关灭活酶抑制剂、外膜透化剂。此外,噬菌体疗法、中药疗法、一氧化氮疗法及纳米技术等特殊治疗也展现出良好的治疗效果,疫苗领域及增强自身免疫力也是未来预防PA感染的重要研究方向。因此,研究PA的耐药机制及治疗技术对PA感染的预防和治疗具有深远的意义。

银屑病的发病机制及临床治疗研究进展

银屑病是一种具有红色丘疹、斑块和银白色鳞片特征的皮肤病。根据皮肤上出现的脓疱大小不同,其可分为脓疱型和非脓疱型两种,对患者的身心健康有巨大影响。目前的治疗方法包括对轻度疾病的局部治疗、光疗法和靶向生物疗法。传统银屑病的治疗往往无法达到预期目标,而高剂量和(或)长期使用药物可能导致患者终末器官损伤。随着对细胞因子在银屑病病因学中作用的进一步了解,靶向肿瘤坏死因子-α和白细胞介素-12/23的生物制剂被开发利用。此外,中医辨证论治方案和纳米技术的开发也为银屑病的治疗提供了新的途径。

针灸领域应用纳米技术的现状及思考

此文阐明纳米技术在针灸中目前的应用和未来的潜力,分别从纳米技术结合针灸针、穴位贴敷与穴位注射、穴位埋线3个方面进行论述。首先,纳米技术与针具制作方面相结合研制出的纳米针灸传感针在实时检测活体活性分子方面提供了新的解决方案;其次,纳米中药与穴位注射、穴位贴敷等针灸特色疗法上的结合也具有很大的潜力;最后,依据纳米技术研发的高抗菌力、低过敏性的纳米银线,应用于临床,为临床穴位埋线治疗疾病提供更优的材料。但从纳米技术在针灸领域的应用现状来看,仍存在着一些待解决的问题,我们需要在不断思考中进一步探索,从而为今后临床治疗提供更多的选择。

纳米技术在医学中的应用

“纳米技术”的概念深深地融入了人类的生活。早在1959年,美国著名理论物理学家理查德·费曼(Richard Feynman)就说过,“存在着一个由微小形态组成的惊人复杂的世界,总有一天(例如2020年)人们会惊讶于1960年以前没有人认真研究过这个世界。”在第一阶段,纳米技术的发展主要取决于探针显微镜设备的开发。这些装置是纳米技术专家的眼睛和手。如今,纳米技术的进步与航空航天,汽车和电子行业纳米材料的开发有关。但越来越多的人提到纳米技术的一个有前途的应用领域——医学。这是因为,现代技术使人们有可能在最近看来不可思议的尺度(微米甚至纳米)上处理物质。这些都是基本生物结构细胞、其组成部分(细胞器)和分子的特征尺寸。

纳米药物的研究进展

纳米科学与技术是近年来迅速发展起来的前沿科技领域 ,并已在各学科的研究中产生了巨大的影响。目前 ,纳米科学与技术在医药领域的应用也取得了令人瞩目的成绩 ,有力地推动了医药科技的发展 ;其在医学和药学方面为疾病的诊断与治疗开辟了一个崭新的领域。本文就纳米药物的概念和特点、制备方法和应用等作一综述 ,对相关技术和方法进行评价和展望 。

纳米技术在中药研究中的应用进展

纳米技术是在纳米尺度下对物质进行制备、研究和工业化,以及利用纳米尺度物质进行交叉研究和工业化的综合性研究体系。中药产生的药理作用不完全归功于该药物特有的化学组成,还应该与药物的物理状态(如颗粒大小)密切相关,通过将纳米技术引入现代中药的研究开发,可以扩展中药的理论和实践研究,扩大中药的应用范围。通过对近年来纳米技术在中药研究中的应用进行综述,介绍了纳米技术应用于中药研究领域的发展状况,重点从纳米中药的特点、类型、制备技术、研究方向、研究中面临的问题等方面进行了系统论述。

纳米技术在医学中的应用

纳米生物技术的研究范围很广，涉及细胞的分离和染色、成像技术、病理诊断、肿瘤早期诊断、纳米药物（基因）载体与纳米药物、纳米生物材料和纳米人工组织、器官等。本文概述了目前国内外纳米技术在现代医学领域中的应用现状，尤其是在纳米检测技术、纳米诊断技术、纳米治疗技术方面的进展。在此基础上，对纳米生物技术在医学领域中进一步的开发应用提出了展望。

纳米技术在中药现代化中的应用

纳米技术的发展为中医药现代化研究提供了新的思路,纳米中药具有独特的作用和优势。本文针对纳米技术在中药制剂中的应用及其范围、存在的问题及发展前景等进行综述。

科技进步与心血管病学的50年展望

本文主要阐述未来 5 0年心血管病学领域内的各种进步 ,包括基因诊断和治疗、心脏外科手术的发展等等。

纳米技术在中医中的应用

纳米技术为中医药发展提供了新的思路和方法。文章通过介绍纳米技术在中医诊疗设备中的应用,概括纳米中药,分析纳米技术对中医理念的启示,从而为中医药学不断吸纳现代科技成果,使中医运用最新研究技术不断发展壮大并与国际接轨提供参考。

中药活性成分纳米系统在抗肿瘤中的应用研究

纳米技术在抗肿瘤研究中的应用日益广泛。天然中草药的抗肿瘤活性成分具备高效、低毒、多靶点等优势,但因它们水溶性低、生物利用度低及存在体内非特异性分布等特点限制其广泛应用。纳米给药系统为抗肿瘤中药的体内靶向传递提供了理想载体,大量研究实例证实纳米载药系统为抗肿瘤中药的临床应用提供了广阔的前景。就中药活性成分靶向抗肿瘤作用原理及各类中药纳米制剂在抗肿瘤方面的应用进行了综述,旨在为中药活性成分的疾病靶向治疗提供参考。

纳米技术在生物医药研究中的应用

纳米技术及纳米材料近几年来在生物学、医学和药学领域的研究和应用方面较为广泛 ,它将对生物医药学领域和传统医学研究产生深远的影响。

纳米中药制剂研究进展

纳米中药是指运用纳米技术制造的、粒径小于100nm的中药有效成分、有效部位、原药及其复方制剂,具有增加药物对血脑屏障或生物膜的穿透性等特点。本文详细介绍了纳米中药的定义、特点,同时介绍了纳米中药制剂技术方面的进展。指出了纳米中药制剂存在的问题,并作了展望。

纳米技术在医学领域的研究应用

纳米是长度的度量单位,又称毫微米,即百万分之一毫米。目前,纳米技术已在多个行业得到了应用,如纳米物理学、纳米电子学、纳米生物学、纳米化学、纳米计量学和纳米加工学等。应用于药物学领域的纳米技术称为纳米药物学。纳米粒在药物学上的应用主要有纳米药物载体和纳米药物制剂2种。纳米药物的生产成本低、效率高、自动化程度高、规模大,而药物的作用也实现了器官靶向、高效和低毒等革命性的突破,并具有稳定性好、对胃肠刺激性小等优点。因此,纳米药物在国际工业领域以及医药领域均具有广阔的发展前景。阐述了纳米技术在医学领域的研究及应用。

纳米中药——中药现代化的新途径

纳米中药是近年来迅速发展起来的前沿科技领域,与传统中药比较有其优势及特色。纳米中药的开发需要多学科的合作与研究,是传统中药走向国际化的方向,具有着广阔的前景。