期刊文献+
共找到7,389篇文章
< 1 2 250 >
每页显示 20 50 100
应用ECHO模型评价药物治疗管理服务在儿童支气管哮喘治疗中的效果
1
作者 连玉菲 邱学佳 +2 位作者 杨玉鹏 刘洪涛 董占军 《医药导报》 CAS 北大核心 2024年第10期1672-1679,共8页
目的探究药物治疗管理(MTM)服务对儿童哮喘治疗的应用效果。方法选取2022年7—12月在河北省人民医院咳喘药学门诊就诊的5~11岁哮喘患儿107例,随机分成对照组(50例)和干预组(52例)。对照组患儿首诊时给予单次吸入制剂教育服务;干预组患... 目的探究药物治疗管理(MTM)服务对儿童哮喘治疗的应用效果。方法选取2022年7—12月在河北省人民医院咳喘药学门诊就诊的5~11岁哮喘患儿107例,随机分成对照组(50例)和干预组(52例)。对照组患儿首诊时给予单次吸入制剂教育服务;干预组患儿给予全程规范化MTM服务。应用经济、临床与人文结果(ECHO)模型,分别于干预前、干预3个月及干预6个月后,统计2组患儿在经济(药物成本、成本-效用比),临床(ACT评分、吸入制剂使用正确率、哮喘发作次数)和人文(EQ-5D-5L效用值、Morisky用药依从性、患者满意度)结果中的差异,评价MTM服务在哮喘患儿中的应用效果。结果干预前2组各项评分指标差异无统计学意义;干预后干预组患儿经济结果、临床结果、人文结果3方面均优于对照组,差异有统计学意义(P<0.05)。结论药师主导的MTM服务可使哮喘患儿在经济、临床、人文多维度获益,既使哮喘患儿疾病得到长期有效控制,又提升药师药学专科服务能力。 展开更多
关键词 echo模型 儿童哮喘 效果评价 吸入制剂
下载PDF
A Novel On-Site-Real-Time Method for Identifying Characteristic Parameters Using Ultrasonic Echo Groups and Neural Network 被引量:1
2
作者 Shuyong Duan Jialin Zhang +2 位作者 Heng Ouyang Xu Han Guirong Liu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第1期215-228,共14页
On-site and real-time non-destructive measurement of elastic constants for materials of a component in a in-service structure is a challenge due to structural complexities,such as ambiguous boundary,variable thickness... On-site and real-time non-destructive measurement of elastic constants for materials of a component in a in-service structure is a challenge due to structural complexities,such as ambiguous boundary,variable thickness,nonuniform material properties.This work develops for the first time a method that uses ultrasound echo groups and artificial neural network(ANN)for reliable on-site real-time identification of material parameters.The use of echo groups allows the use of lower frequencies,and hence more accommodative to structural complexity.To train the ANNs,a numerical model is established that is capable of computing the waveform of ultrasonic echo groups for any given set of material properties of a given structure.The waveform of an ultrasonic echo groups at an interest location on the surface the structure with material parameters varying in a predefined range are then computed using the numerical model.This results in a set of dataset for training the ANN model.Once the ANN is trained,the material parameters can be identified simultaneously using the actual measured echo waveform as input to the ANN.Intensive tests have been conducted both numerically and experimentally to evaluate the effectiveness and accuracy of the currently proposed method.The results show that the maximum identification error of numerical example is less than 2%,and the maximum identification error of experimental test is less than 7%.Compared with currently prevailing methods and equipment,the proposefy the density and thickness,in addition to the elastic constants.Moreover,the reliability and accuracy of inverse prediction is significantly improved.Thus,it has broad applications and enables real-time field measurements,which has not been fulfilled by any other available methods or equipment. 展开更多
关键词 Parameter identification Ultrasonic echo group High-precision modeling Artificial neural network NDT
下载PDF
Exploring the associations between skeletal muscle echogenicity and physical function in aging adults:A systematic review with meta-analyses
3
作者 Dustin J.Oranchuk Stephan G.Bodkin +1 位作者 Katie L.Boncella Michael O.Harris-Love 《Journal of Sport and Health Science》 SCIE CAS CSCD 2024年第6期820-840,共21页
Background:Assessment and quantification of skeletal muscle within the aging population is vital for diagnosis,treatment,and injury/disease prevention.The clinical availability of assessing muscle quality through diag... Background:Assessment and quantification of skeletal muscle within the aging population is vital for diagnosis,treatment,and injury/disease prevention.The clinical availability of assessing muscle quality through diagnostic ultrasound presents an opportunity to be utilized as a screening tool for function-limiting diseases.However,relationships between muscle echogenicity and clinical functional assessments require authoritative analysis.Thus,we aimed to(a) synthesize the literature to assess the relationships between skeletal muscle echogenicity and physical function in older adults(≥60 years),(b) perform pooled analyses of relationships between skeletal muscle echogenicity and physical function,and(c) perform sub-analyses to determine between-muscle relationships.Methods:CINAHL,Embase,MEDLINE,PubMed,and Web of Science databases were systematically searched to identify articles relating skeletal muscle echogenicity to physical function in older adults.Risk-of-bias assessments were conducted along with funnel plot examination.Meta-analyses with and without sub-analyses for individual muscles were performed utilizing Fisher's Z transformation for the most common measures of physical function.Fisher's Z was back-transformed to Pearson's r for interpretation.Results:Fifty-one articles(n=5095,female=~2759,male=~2301,72.5± 5.8 years,mean±SD(1 study did not provide sex descriptors))were extracted for review,with previously unpublished data obtained from the authors of 13 studies.The rectus femoris(n=34) and isometric knee extension strength(n=22) were the most accessed muscle and physical qualities,respectively.The relationship between quadriceps echogenicity and knee extensor strength was moderate(n=2924,r=-0.36(95% confidence interval:-0.38 to-0.32),p <0.001),with all other meta-analyses(grip strength,walking speed,sit-to-stand,timed up-and-go) resulting in slightly weaker correlations(r:-0.34 to-0.23,all p <0.001).Sub-analyses determined minimal differences in predictive ability between muscle groups,although combining muscles(e.g.,rectus femoris+vastus lateralis) often re sulted in stronger correlations with maximal strength.Conclusion:While correlations are modest,the affordable,portable,and noninvasive ultrasonic assessment of muscle quality is a consistent predictor of physical function in older adults.Minimal between-muscle differences suggest that echogenicity estimates of muscle quality are systemic.Therefore,practitioners may be able to scan a single muscle to estimate full-body skeletal muscle quality/composition,while researchers should consider combining multiple muscles to strengthen the model. 展开更多
关键词 CORRELATIONS echo intensity ELDERLY Intramuscular fat Strength
下载PDF
Standard-definition White-light,High-definition White-light versus Narrow-band Imaging Endoscopy for Detecting Colorectal Adenomas:A Multicenter Randomized Controlled Trial
4
作者 Chang-wei DUAN Hui-hong ZHAI +10 位作者 Hui XIE Xian-zong MA Dong-liang YU Lang YANG Xin WANG Yu-fen TANG Jie ZHANG Hui SU Jian-qiu SHENG Jun-feng XU Peng JIN 《Current Medical Science》 SCIE CAS 2024年第3期554-560,共7页
Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colore... Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colorectal lesions in the Chinese population.Methods This was a multicenter,single-blind,randomized,controlled trial with a non-inferiority design.Patients undergoing endoscopy for physical examination,screening,and surveillance were enrolled from July 2017 to December 2020.The primary outcome measure was the adenoma detection rate(ADR),defined as the proportion of patients with at least one adenoma detected.The associated factors for detecting adenomas were assessed using univariate and multivariate logistic regression.Results Out of 653 eligible patients enrolled,data from 596 patients were analyzed.The ADRs were 34.5%in the SD-WL group,33.5%in the HD-WL group,and 37.5%in the HD-NBI group(P=0.72).The advanced neoplasm detection rates(ANDRs)in the three arms were 17.1%,15.5%,and 10.4%(P=0.17).No significant differences were found between the SD group and HD group regarding ADR or ANDR(ADR:34.5%vs.35.6%,P=0.79;ANDR:17.1%vs.13.0%,P=0.16,respectively).Similar results were observed between the HD-WL group and HD-NBI group(ADR:33.5%vs.37.7%,P=0.45;ANDR:15.5%vs.10.4%,P=0.18,respectively).In the univariate and multivariate logistic regression analyses,neither HD-WL nor HD-NBI led to a significant difference in overall adenoma detection compared to SD-WL(HD-WL:OR 0.91,P=0.69;HD-NBI:OR 1.15,P=0.80).Conclusion HD-NBI and HD-WL are comparable to SD-WL for overall adenoma detection among Chinese outpatients.It can be concluded that HD-NBI or HD-WL is not superior to SD-WL,but more effective instruction may be needed to guide the selection of different endoscopic methods in the future.Our study’s conclusions may aid in the efficient allocation and utilization of limited colonoscopy resources,especially advanced imaging technologies. 展开更多
关键词 standard-definition white-light endoscopy high-definition white-light endoscopy narrow-band imaging colonoscopy colorectal cancer screening adenoma detection rate
下载PDF
Could near focus endoscopy,narrow-band imaging,and acetic acid improve the visualization of microscopic features of stomach mucosa?
5
作者 Admir Kurtcehajic Enver Zerem +5 位作者 Tomislav Bokun Ervin Alibegovic Suad Kunosic Ahmed Hujdurovic Amir Tursunovic Kenana Ljuca 《World Journal of Gastrointestinal Endoscopy》 2024年第3期157-167,共11页
BACKGROUND Conventional magnifying endoscopy with narrow-band imaging(NBI)observation of the gastric body mucosa shows dominant patterns in relation to the regular arrangement of collecting venules,subepithelial capil... BACKGROUND Conventional magnifying endoscopy with narrow-band imaging(NBI)observation of the gastric body mucosa shows dominant patterns in relation to the regular arrangement of collecting venules,subepithelial capillary network,and gastric pits.AIM To evaluate the effectiveness of a new one-dual(near)focus,NBI mode in the assessment of the microscopic features of gastric body mucosa compared to conventional magnification.METHODS During 2021 and 2022,68 patients underwent proximal gastrointestinal endoscopy using magnification endoscopic modalities subsequently applying acetic acid(AA).The GIF-190HQ series NBI system with dual focus capability was used for the investigation of gastric mucosa.At the time of the endoscopy,the gastric body mucosa of all enrolled patients was photographed using the white light endoscopy(WLE),near focus(NF),NF-NBI,AA-NF,and AA-NF-NBI modes.RESULTS The WLE,NF and NF-NBI endoscopic modes for all patients(204 images)were classified in the same order into three groups.Two images from each patient for the AA-NF and AA-NF-NBI endoscopic modes were classified in the same order.According to all three observers who completed the work independently,NF magnification was significantly superior to WLE(P<0.01),and the NF-NBI mode was significantly superior to NF magnification(P<0.01).After applying AA,the three observers confirmed that AA-NF-NBI was significantly superior to AA-NF(P<0.01).Interobserver kappa values for WLE were 0.609,0.704,and 0.598,respectively and were 0.600,0.721,and 0.637,respectively,for NF magnification.For the NF-NBI mode,the values were 0.378,0.471,and 0.553,respectively.For AA-NF,they were 0.453,0.603,and 0.480,respectively,and for AA-NF-NBI,they were 0.643,0.506,and 0.354,respectively.CONCLUSION When investigating gastric mucosa in microscopic detail,NF-NBI was the most powerful endoscopic mode for assessing regular arrangement of collecting venules,subepithelial capillary network,and gastric pits among the five endoscopic modalities investigated in this study.AA-NF-NBI was the most powerful endoscopic mode for analyzing crypt opening and intervening part. 展开更多
关键词 Gastric mucosa Endoscopic microanatomy Magnifying endoscopy Near focus narrow-band imaging Acetic acid
下载PDF
Research on Sleeve Grouting Density Detection Based on the Impact Echo Method
6
作者 Pu Zhang Yingjun Li +5 位作者 Xinyu Zhu Shizhan Xu Pinwu Guan Wei Liu Yanwei Guo Haibo Wang 《Structural Durability & Health Monitoring》 EI 2024年第2期143-159,共17页
Grouting defects are an inherent challenge in construction practices,exerting a considerable impact on the operational structural integrity of connections.This investigation employed the impact-echo technique for the ... Grouting defects are an inherent challenge in construction practices,exerting a considerable impact on the operational structural integrity of connections.This investigation employed the impact-echo technique for the detection of grouting anomalies within connections,enhancing its precision through the integration of wavelet packet energy principles for damage identification purposes.A series of grouting completeness assessments were meticulously conducted,taking into account variables such as the divergent material properties of the sleeves and the configuration of adjacent reinforcement.The findings revealed that:(i)the energy distribution for the highstrength concrete cohort predominantly occupied the frequency bands 42,44,45,and 47,whereas for other groups,it was concentrated within the 37 to 40 frequency band;(ii)the delineation of empty sleeves was effectively discernible by examining the wavelet packet energy ratios across the spectrum of frequencies,albeit distinguishing between sleeves with 50%and full grouting density proved challenging;and(iii)the wavelet packet energy analysis yielded variable detection outcomes contingent on the material attributes of the sleeves,demonstrating heightened sensitivity when applied to ultrahigh-performance concrete matrices and GFRP-reinforced steel bars. 展开更多
关键词 Prefabricated building steel grouting sleeve impact echo method wavelet packet energy grouted defect
下载PDF
Enhanced air-coupled impact echo technique by phase analysis of signals from multiple sensors
7
作者 Najjiya Almallah Nenad Gucunski 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期297-310,共14页
This paper presents an air-coupled impact echo(IE)technique that relies on the phase spectrum of the collected data to find the frequencies corresponding to the reflections from delaminations.The proposed technique ta... This paper presents an air-coupled impact echo(IE)technique that relies on the phase spectrum of the collected data to find the frequencies corresponding to the reflections from delaminations.The proposed technique takes advantage of the fact that the IE compression wave is not a propagating wave,but it is the 1st order symmetrical(S1)mode Lamb wave at zero group velocity(S1-ZGV).Therefore,it searches the phase spectra of the data collected by multiple sensors to locate the frequency corresponding to the lowest phase difference.As a result,the technique reduces the effect of propagating waves,including the direct acoustic wave and ambient noise.It is named the Constant Phase IE(CPIE).The performance of the CPIE is experimentally compared with the regular amplitude spectrum-based IE technique and two other multisensor IE techniques.The CPIE shows a performance advantage,especially in a noisy environment. 展开更多
关键词 nondestructive testing(NDT) nondestructive evaluation(NDE) bridge inspection bridge evaluation impact echo bridge delamination concrete bridge deck air-coupled sensing MEMS
下载PDF
Relationship of inflammatory indices with left atrial appendage thrombus or spontaneous echo contrast in patients with atrial fibrillation
8
作者 Zhao Wang Bin-Hao Wang +3 位作者 Xiao-Lei Yang Yun-Long Xia Sheng-Min Zhang Ying Che 《World Journal of Clinical Cases》 SCIE 2024年第21期4550-4557,共8页
BACKGROUND Inflammatory indices derived from complete blood tests have been reported to be associated with poor outcomes in patients with atrial fibrillation(AF).The data about the relationship between inflammatory in... BACKGROUND Inflammatory indices derived from complete blood tests have been reported to be associated with poor outcomes in patients with atrial fibrillation(AF).The data about the relationship between inflammatory indices and left atrial appendage thrombus(LAAT)or dense spontaneous echo contrast(SEC)are limited.AIM To explore the value of inflammatory indices for predicting the presence of LAAT or dense SEC in nonvalvular AF patients.METHODS A total of 406 patients with nonvalvular AF who underwent transesophageal echocardiography were included and divided into two groups based on the presence(study group)or absence(control group)of LAAT or dense SEC.Inflammatory indices,including the neutrophil-to-lymphocyte ratio(NLR),platelet–tolymphocyte ratio(PLR),and lymphocyte-to-monocyte ratio(LMR),were calculated from complete blood analysis.The associations of inflammatory indices RESULTS LAAT and dense SEC were detected in 11(2.7%)and 42(10.3%)patients,respectively.The PLR only showed an association with LAAT/dense SEC in the univariate model.Elevated NLR(odds ratio[OR]=1.48,95%confidence interval[CI]:1.11-1.98,P=0.007)and reduced LMR(OR=0.59,95%CI:0.41-0.83,P=0.003)were found to be independent risk factors for the presence of LAAT/dense SEC.The areas under the NLR and LMR curves for predicting LAAT/dense SEC were 0.73(95%CI:0.66-0.80,P<0.001)and 0.73(95%CI:0.65-0.81,P<0.001),respectively,while the cutoff values were 2.8(sensitivity:69.8%;specificity:64.0%)and 2.4(sensitivity:71.7%;specificity:60.6%),respectively.CONCLUSION Increased NLR and decreased LMR may predict LAAT/dense SEC in patients with nonvalvular AF. 展开更多
关键词 Nonvalvular atrial fibrillation Left atrial appendage thrombus Spontaneous echo contrast Neutrophil–lymphocyte ratio Lymphocyte–monocyte ratio
下载PDF
连云港市一起ECHO_(30)病毒性脑膜炎爆发流行病学调查 被引量:11
9
作者 朱磷扬 张廷禄 +4 位作者 朱凤东 许雷 孙波 潘红星 赵玉良 《疾病监测》 CAS 2007年第6期384-387,共4页
目的分析2006年江苏省连云港市病毒性脑膜炎爆发的流行特征、影响因素和病因。方法采用统一的流行病学调查表对病例进行调查,收集2004年以来全市各县区病毒性脑膜炎住院病例资料,采用1:2配比病例对照研究的方法分析流行因素;24份脑脊液... 目的分析2006年江苏省连云港市病毒性脑膜炎爆发的流行特征、影响因素和病因。方法采用统一的流行病学调查表对病例进行调查,收集2004年以来全市各县区病毒性脑膜炎住院病例资料,采用1:2配比病例对照研究的方法分析流行因素;24份脑脊液标本送江苏省疾病控制中心检测,并进行病毒分离。结果2004-2005年全市各县区病毒性脑膜炎病例呈现散发状态;2006年1~7月份共查出病例数为968例,从6月份起出现疫情上升,1县2区出现爆发,7月份达高峰,爆发病例为473例,占全市总病例数的48.86%;主要累及15岁以下儿童,占94.44%;男性多于女性,男女比为2.65:1;主要临床表现为发热、头痛、呕吐、脑膜刺激征阳性、脑脊液有核细胞增多。饭前洗手与多吃瓜果为保护因素,说明该病与不良卫生习惯有关系。23份脑脊液经PCR检测,16份ECHO_(30)肠道病毒阳性。结论2006年夏季江苏省连云港市病毒性脑膜炎出现一次爆发并波及1县2区,致病病原体为埃可30型肠道病毒(Echovirus 30,ECHO_(30))肠道病毒,不良卫生习惯可能是导致该病发生流行的危险因素。 展开更多
关键词 echo30 脑膜炎 爆发 流行病学调查
下载PDF
福建省2011年病毒性脑炎暴发病原Echo30分子流行病学分析 被引量:22
10
作者 杨秀惠 严延生 +6 位作者 翁育伟 何爱华 张红榕 陈炜 许江阳 林其财 周勇 《中国人兽共患病学报》 CAS CSCD 北大核心 2012年第3期265-269,共5页
目的了解福建省2011年病毒性脑炎暴发的病原特点及福建省近10年Echo30分子流行病学特征。方法应用细胞培养法获得病毒株,微量血清中和试验或RT-PCR序列分析鉴定Echo30血清型,提取病毒RNA核酸,逆转录为cD-NA,分段扩增VP1基因序列全长,测... 目的了解福建省2011年病毒性脑炎暴发的病原特点及福建省近10年Echo30分子流行病学特征。方法应用细胞培养法获得病毒株,微量血清中和试验或RT-PCR序列分析鉴定Echo30血清型,提取病毒RNA核酸,逆转录为cD-NA,分段扩增VP1基因序列全长,测定并分析扩增产物的序列。结果 2011年4月1日-6月2日,从福建省4个县(市)区病毒性脑炎病例标本中分离的病毒经鉴定均为Echo30;VP1基因序列分析显示,泉州市安溪和德化两地流行株高度同源(核苷酸与氨基酸序列同源性分别为99.0%和99.6%),同福安和厦门流行株(核苷酸与氨基酸序列同源性分别为98.5%和100%)核苷酸差异约9%,3个位点氨基酸出现了变异。近10年福建省Echo30分子流行病学分析显示,2011年泉州流行株并非由2005年当地流行株进化而来,而与2008年河南省分离株(HQ625646-Henan/04/2008)同源性最高;近10年福建省Echo30存在多基因型、多谱系的同时传播,并在2006年发现了两株第III新基因型病毒。结论造成2011年福建省病毒性脑炎暴发的病原为Echo30,且至少存在两条不同传播链病毒同时流行。Echo30福建株呈多基因型、多谱系分布流行特点。 展开更多
关键词 病毒性脑炎 echo30 VP1基因 分子流行病学
下载PDF
一起ECHO 30病毒引发游泳队脑炎爆发调查 被引量:2
11
作者 曾士典 章显权 +1 位作者 贾俐挺 谢海滨 《疾病监测》 CAS 2007年第3期170-171,共2页
目的分析ECHO30病毒性脑炎在冬季体校游泳队爆发的特征。方法应用流行病学描述方法,对体校学生进行筛查;采集典型病例脑脊液(CSF)、血液样本和泳池水样进行实验室检测。结果病例均为体校游泳队学生,共发病37例,罹患率25.18%,性别间罹患... 目的分析ECHO30病毒性脑炎在冬季体校游泳队爆发的特征。方法应用流行病学描述方法,对体校学生进行筛查;采集典型病例脑脊液(CSF)、血液样本和泳池水样进行实验室检测。结果病例均为体校游泳队学生,共发病37例,罹患率25.18%,性别间罹患率差异无统计学意义(x2=0.03,P>0.50),流行9d;游泳池水污染严重,6份CSF样本肠道病毒核糖核酸阳性,2份分离到ECHO30肠道病毒。结论游泳池循环净水和消毒设备应正常运转,日常监督监测应加强。 展开更多
关键词 echo 30 病毒性脑炎 爆发
下载PDF
ECHO 19引起龙岩市儿童病毒性脑炎的流行病学调查 被引量:11
12
作者 陈前进 俞新莲 +5 位作者 张月花 杨秀惠 严延生 黄开华 吴水新 邓小如 《海峡预防医学杂志》 CAS 2005年第4期14-16,共3页
[目的]探讨龙岩市2004年儿童病毒性脑炎流行的病因、流行规律及特征.[方法]对142例病毒性脑炎病例进行流行病学调查,对其中30例的脑脊液标本进行病毒分离和型别鉴定.[结果]142例患者分布在我市的6个县(市、区),其中新罗区占(66.2%),另... [目的]探讨龙岩市2004年儿童病毒性脑炎流行的病因、流行规律及特征.[方法]对142例病毒性脑炎病例进行流行病学调查,对其中30例的脑脊液标本进行病毒分离和型别鉴定.[结果]142例患者分布在我市的6个县(市、区),其中新罗区占(66.2%),另有广东省大埔县2例;年龄以5~12岁为多;男性68.3%,女性31.7%;5~6月为发病高峰.临床主要表现为突然发病、发热(92.4%)、头痛(83.1%)、呕吐(68.6%)等;脑电图以轻中度异常为主;67.8%血常规正常;脑脊液常规87.5%颅内压力增高,56.8%细胞数增加.疗程10天左右.从30份脑脊液中检出16株ECHO 19病毒.[结论]流行病学调查及实验室病原检测确认,龙岩市儿童病毒性脑炎病原为ECHO 19. 展开更多
关键词 病毒性脑炎 echo19 儿童 流行病学调查 脑脊液
下载PDF
急性弛缓性麻痹病例中ECHO11病毒的基因特征分析 被引量:4
13
作者 刘桂艳 许文波 +5 位作者 纪峰 张勇 王海岩 李岩 严冬梅 徐爱强 《病毒学报》 CAS CSCD 北大核心 2006年第1期22-30,共9页
该文首次分析了我国ECHO11病毒的分子流行病学资料。1999~2004年,ECHO11病毒是山东省急性弛缓性麻痹(AFP)病例中分离到的优势毒株,2003年从山东省482例AFP病例中共分离到11株ECHO11病毒,其中相关的10例病例分布跨越山东省大部分... 该文首次分析了我国ECHO11病毒的分子流行病学资料。1999~2004年,ECHO11病毒是山东省急性弛缓性麻痹(AFP)病例中分离到的优势毒株,2003年从山东省482例AFP病例中共分离到11株ECHO11病毒,其中相关的10例病例分布跨越山东省大部分地区,但发病日期集中在7月和12月。该研究试图通过对VP1编码基因全序列的测定和分析,为探讨ECHO11病毒与AFP之间的病因关系提供线索。分子流行病学研究提示,11株ECHO11毒株都位于同一传播链,核苷酸同源性为97.2%~100%,氨基酸同源性为99.6%~100%,其中7月和12月的分离株之间相层8~9个核苷酸,氨基酸序列一致。这说明山东省2003年7月和12月分别发生了ECHO11病毒流行,但这些毒株与AFP的病因关系尚需进一步研究。11株病毒组成了A基因型中的一个新亚型,在进化树上单独呈密切相关的一簇,与同基因型内的其它亚型的核苷酸同源性为82.2%~84.7%,氨基酸同源性为94.8%~97.6%. 展开更多
关键词 急性弛缓性麻痹病例 echo11病毒 基因特征
下载PDF
Radar Echo and Lightning Characteristics Analysis on A Strong Thunderstorm Weather in Fuxin 被引量:1
14
作者 马虹旭 杨仲江 +1 位作者 王伟 才奎志 《Meteorological and Environmental Research》 CAS 2010年第5期48-50,101,共4页
Based on the radar data and lightning position indicator data of strong thunderstorm weather which happened in Fuxin on July 8,2007,the relationship between the lightning activity and the radar echo was analyzed.The r... Based on the radar data and lightning position indicator data of strong thunderstorm weather which happened in Fuxin on July 8,2007,the relationship between the lightning activity and the radar echo was analyzed.The results showed that Fuxin area located in the cross position of T-shaped trough and was affected by the cold air which continuously glided down.The corresponding warm front on the ground advanced southward and arrived here.It was the weather background of this thunderstorm weather.The position variation of lightning occurrence was closely related to the strong echo movement of squall line,and the velocity echo clearly reflected and predicted the movement tendency of the radar echo. 展开更多
关键词 Strong thunderstorm weather Radar echo LIGHTNING Fuxin China
下载PDF
一次由双重抗原型ECHO病毒引起的无菌性脑膜炎流行 被引量:2
15
作者 江永珍 张礼璧 +3 位作者 王大明 王南达 吕敏乐 贾维国 《病毒学报》 CAS CSCD 北大核心 1990年第2期133-139,共7页
1987年2~8月,山东省招远县发生一起不明病因的无菌性脑膜炎流行,全县有2646人发病.病死3人。从收集的22人份粪便中分离到3株病毒,经鉴定为耐酸的RNA型病毒.检测13例患者的双份血清,恢复期血清对该病毒中和抗体呈4倍以上升高者5例,抗体... 1987年2~8月,山东省招远县发生一起不明病因的无菌性脑膜炎流行,全县有2646人发病.病死3人。从收集的22人份粪便中分离到3株病毒,经鉴定为耐酸的RNA型病毒.检测13例患者的双份血清,恢复期血清对该病毒中和抗体呈4倍以上升高者5例,抗体阳转者2例,抗体呈4倍降低者1例.经血清学定型该病毒为ECHO29和ECHO2型双重抗原性的病毒。 展开更多
关键词 echo 病毒感染 脑膜炎 无菌性
下载PDF
事件驱动的B/S系统开发框架Echo研究 被引量:1
16
作者 吴江 马瑞芳 《微电子学与计算机》 CSCD 北大核心 2004年第2期10-14,共5页
传统的B/S开发框架受HTTP协议及浏览器功能的限制,开发的程序在界面、功能上存在着一定的不足。同时,混用HTML、JavaScript等语言增大了开发的难度,并且使得程序的性能、可移植性大大下降。文章介绍了新出现的一种纯事件驱动和面向对象... 传统的B/S开发框架受HTTP协议及浏览器功能的限制,开发的程序在界面、功能上存在着一定的不足。同时,混用HTML、JavaScript等语言增大了开发的难度,并且使得程序的性能、可移植性大大下降。文章介绍了新出现的一种纯事件驱动和面向对象的B/S开发框Echo的技术和应用,给出了解决这一系列问题的一个思路:利用Echo框架,可以完全使用单一的面相对象的Java语言,开发出事件驱动的具有良好可维护性和可移植的B/S系统。 展开更多
关键词 软件开发 程序界面 事件驱动 B/S系统 echo JAVASCRIPT语言
下载PDF
上海市人群Echo30病毒性脑膜炎隐性感染调查 被引量:5
17
作者 高洁 赵雅男 姜庆五 《病毒学报》 CAS CSCD 北大核心 2007年第2期121-124,共4页
为了了解上海市不同年龄组人群的Echo30病毒隐性感染情况及IgG抗体阳性率分布。采集上海市412份不同年龄组人群血清,用间接酶联免疫吸附试验(ELISA)检测血清中的Echo30IgG抗体。发现受检普通人群血清中Echo30IgG抗体阳性率为25.8%。其中... 为了了解上海市不同年龄组人群的Echo30病毒隐性感染情况及IgG抗体阳性率分布。采集上海市412份不同年龄组人群血清,用间接酶联免疫吸附试验(ELISA)检测血清中的Echo30IgG抗体。发现受检普通人群血清中Echo30IgG抗体阳性率为25.8%。其中1岁以下婴幼儿中未见抗体阳性者,15岁以下儿童抗体阳性率较低(10%~16.7%),15岁以上人群抗体阳性率水平明显升高(45.0%~46.7%)。孕妇与普通人群抗体阳性率无显著性差异。研究结果提示上海市人群中存在隐性感染者,人群通过自然感染获得免疫保护,15岁以下儿童为Echo30感染及发病的高危人群,母体传递给婴幼儿的抗体水平较低,不能为婴幼儿提供先天性免疫保护。 展开更多
关键词 埃可病毒30型(echo30) 无菌性脑膜炎 肠道病毒 隐性感染
下载PDF
一起儿童病毒性脑炎暴发肠道病毒ECHO6型分离株VP1基因特征分析 被引量:13
18
作者 陈前进 曹春远 +4 位作者 吴水新 杨秀惠 罗招福 何云 廖亦红 《中国人兽共患病学报》 CAS CSCD 北大核心 2013年第5期523-526,共4页
目的对埃可病毒6型(ECHO6)福建龙岩分离株进行分子生物学分析,阐明ECHO6病毒福建龙岩分离株的分子生学特征及其与世界其它分离株的基因关系。方法采集暴发病例脑脊液标本,用RD细胞进行分离病毒,阳性分离物采用中和试验及PCR序列分析确... 目的对埃可病毒6型(ECHO6)福建龙岩分离株进行分子生物学分析,阐明ECHO6病毒福建龙岩分离株的分子生学特征及其与世界其它分离株的基因关系。方法采集暴发病例脑脊液标本,用RD细胞进行分离病毒,阳性分离物采用中和试验及PCR序列分析确定其血清型别;RT-PCR扩增VP1基因全长,测定序列进行同源性及亲缘进化树分析。结果 13例细胞培养阳性分离物经中和试验及序列分析结果均为ECHO6。随机选取4株病毒株进行VP1全基因序列分析显示:4个病毒株之间同源性>99%;与山东病毒株E6/SD/sewage/081226/2-2同源性高于其他参考株。在遗传进化树上,4株分离病毒株同属一个分支,为C2亚型。结论 ECHO6是引起本次福建省龙岩市长汀县儿童病毒性脑炎暴发的病原体,其基因型为C2亚型。 展开更多
关键词 病毒性脑炎 埃可病毒6型 序列分析 基因特征
下载PDF
银川市某医院体检人群EV71型和ECHO病毒感染率的调查 被引量:7
19
作者 白永生 杨安宁 +3 位作者 张静 孙炜炜 王菊 郭爱玲 《宁夏医科大学学报》 2012年第5期453-455,共3页
目的了解银川市不同年龄组人群肠道病毒71型(EV71型)和埃克病毒(ECHO)感染率情况及IgG抗体阳性率分布情况。方法采集宁夏银川市某医院204份不同年龄组体检人群血清,用间接酶联免疫吸附试验(ELISA)检测血清中的EV71型和ECHO IgG抗体。结... 目的了解银川市不同年龄组人群肠道病毒71型(EV71型)和埃克病毒(ECHO)感染率情况及IgG抗体阳性率分布情况。方法采集宁夏银川市某医院204份不同年龄组体检人群血清,用间接酶联免疫吸附试验(ELISA)检测血清中的EV71型和ECHO IgG抗体。结果 204例受检人群血清中EV71型和ECHO IgG阳性率分别为32.4%和15.1%,其中1岁以内婴幼儿EV71抗体阳性率低,1岁~组EV71 IgG抗体阳性率最高达48.3%,但与其他组比较差异无统计学意义。1岁以内婴幼儿ECHO抗体阳性率低,随着年龄增长,抗体阳性率增高,15~65岁组ECHO IgG抗体阳性率最高,为22.3%,与其他组比较差异无统计学意义。结论普通人群中可能存在EV71型和ECHO隐性感染者,成人EV71隐性感染率较低,儿童是EV71的主要感染者,15岁以下儿童为ECHO感染的高危人群,人群通过自然感染获得免疫保护。 展开更多
关键词 肠道病毒71型(EV71) 埃可病毒(echo) 隐性感染
下载PDF
基于Echoview声学数据后处理系统的背景噪声扣除方法 被引量:13
20
作者 张俊 陈丕茂 +3 位作者 陈国宝 于杰 范江涛 邱永松 《渔业科学进展》 CSCD 北大核心 2014年第1期9-17,共9页
基于2012年2~3月南海中部鱼类资源声学调查资料,利用Echoview系统中虚拟变量模块的功能,探讨扣除背景噪声对声学映像、单脉冲回声信号图、海里面积散射系数(NASC)和体积反向散射强度(Sv)的影响.结果显示,背景噪声对120kHz数据的干... 基于2012年2~3月南海中部鱼类资源声学调查资料,利用Echoview系统中虚拟变量模块的功能,探讨扣除背景噪声对声学映像、单脉冲回声信号图、海里面积散射系数(NASC)和体积反向散射强度(Sv)的影响.结果显示,背景噪声对120kHz数据的干扰明显强于38kHz;随着水深逐渐增加,扣除背景噪声后,120kHz声学映像变化亦比38kHz更加明显;扣除背景噪声时,换能器表面1 m处的Sv值在不断改变过程中,相同水层中不同频率数据的NASC和Sv的变化差异明显,其差异程度因具体水层而异,相同频率数据在不同水层的NASC和Sv的变化差异亦明显.分析认为,扣除背景噪声非常必要;本研究的方法能够较好地排除背景噪声,是提高资源评估准确度的有效手段. 展开更多
关键词 回声积分 时变增益 背景噪声消除 虚拟变量法
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部