ObjectiveTo compare the effects of oral intake and nasogastric tube(NG)feeding on nutritional status,complications and survival during neoadjuvant chemoradiotherapy for esophageal squamous-cell carcinoma(ESCC)patients...ObjectiveTo compare the effects of oral intake and nasogastric tube(NG)feeding on nutritional status,complications and survival during neoadjuvant chemoradiotherapy for esophageal squamous-cell carcinoma(ESCC)patients.MethodsA total of 61 ESCC cases treated with neoadjuvant chemoradiotherapy from December 2018 to March 2020 were enrolled,including(38 in oral intake group,and 22 in NG feeding group.Disease characteristics and baseline nutritional markers were collected in both groups.Nutritional status,complication and completion rate of chemoradiotherapy in both groups were evaluated.ResultsCompared with the oral intake group,patients in the NG feeding group had a later T stage(P=0.027)and clinical stage(P=0.014).The levels of energy intake(P=0.033),serum prealbumin(P<0.001),albumin(P=0.017)and hemoglobin(P=0.015)before treatment in NG group were significantly lower than those in oral intake group.Furthermore,patient-generated subjective global assessment(PG-SGA)score(P=0.016)and the levels of serum C-reactive protein(P=0.014)of NG feeding group were significantly higher than those of oral intake group.However,at the end of treatment,PG-SGA scores were increased in oral intake group and decreased in NG feeding group.In addition,the NG feeding group had a lower incidence of grade≥2 esophagitis(P=0.037),and higher completion rate of chemotherapy compared with oral intake group(P=0.034).Meanwhile,the proportion of parenteral nutrition(P=0.008)and anti-inflammatory(P=0.022)treatment in NG feeding group was significantly lower than that in oral intake group.Although patients in the NG feeding group had a worse prognosis,there were no statistically significant differences in overall survival(OS)and progression-free survival(PFS)between the two groups(P>0.05).ConclusionsAs a safe and effective enteral nutrition approach to improving nutrition,nasogastric tube feeding could increase treatment completion rate and reduce the incidence of≥grade 2 esophagitis reaction during neoadjuvant chemoradiotherapy.展开更多
目的了解管饲期间护士胃管定位方法的现状并分析其影响因素。方法根据AACN(American Association of Critical-Care Nurses)实践警报,自行设计调查问卷,对957名临床护士进行问卷调查。结果管饲期间护士胃管定位的时间选择存在差异,291人...目的了解管饲期间护士胃管定位方法的现状并分析其影响因素。方法根据AACN(American Association of Critical-Care Nurses)实践警报,自行设计调查问卷,对957名临床护士进行问卷调查。结果管饲期间护士胃管定位的时间选择存在差异,291人(32.08%)选择在管饲饮食前+交接班时;胃管定位的方法选择中,497人(51.93%)通过听诊腹部气过水声定位,564人(58.93%)回抽胃内容物定位,而AACN推荐的最简单直观的胃管刻度确定法和pH值测试法,仅393人(41.06%)和31人(3.24%)总是使用。不同医院级别、是否ICU护士选择胃管刻度确定法及不同医院级别、护龄、学历、职称、是否专科护士选择pH值测试法存在差异(P<0.05,P<0.01)。结论管饲期间护士胃管定位方法的选择与实践警报推荐存在一定差距。护士应转变观念,加强相关理论知识学习和进行积极地循证护理实践,以更准确有效地实施临床护理操作。展开更多
文摘ObjectiveTo compare the effects of oral intake and nasogastric tube(NG)feeding on nutritional status,complications and survival during neoadjuvant chemoradiotherapy for esophageal squamous-cell carcinoma(ESCC)patients.MethodsA total of 61 ESCC cases treated with neoadjuvant chemoradiotherapy from December 2018 to March 2020 were enrolled,including(38 in oral intake group,and 22 in NG feeding group.Disease characteristics and baseline nutritional markers were collected in both groups.Nutritional status,complication and completion rate of chemoradiotherapy in both groups were evaluated.ResultsCompared with the oral intake group,patients in the NG feeding group had a later T stage(P=0.027)and clinical stage(P=0.014).The levels of energy intake(P=0.033),serum prealbumin(P<0.001),albumin(P=0.017)and hemoglobin(P=0.015)before treatment in NG group were significantly lower than those in oral intake group.Furthermore,patient-generated subjective global assessment(PG-SGA)score(P=0.016)and the levels of serum C-reactive protein(P=0.014)of NG feeding group were significantly higher than those of oral intake group.However,at the end of treatment,PG-SGA scores were increased in oral intake group and decreased in NG feeding group.In addition,the NG feeding group had a lower incidence of grade≥2 esophagitis(P=0.037),and higher completion rate of chemotherapy compared with oral intake group(P=0.034).Meanwhile,the proportion of parenteral nutrition(P=0.008)and anti-inflammatory(P=0.022)treatment in NG feeding group was significantly lower than that in oral intake group.Although patients in the NG feeding group had a worse prognosis,there were no statistically significant differences in overall survival(OS)and progression-free survival(PFS)between the two groups(P>0.05).ConclusionsAs a safe and effective enteral nutrition approach to improving nutrition,nasogastric tube feeding could increase treatment completion rate and reduce the incidence of≥grade 2 esophagitis reaction during neoadjuvant chemoradiotherapy.
文摘目的了解管饲期间护士胃管定位方法的现状并分析其影响因素。方法根据AACN(American Association of Critical-Care Nurses)实践警报,自行设计调查问卷,对957名临床护士进行问卷调查。结果管饲期间护士胃管定位的时间选择存在差异,291人(32.08%)选择在管饲饮食前+交接班时;胃管定位的方法选择中,497人(51.93%)通过听诊腹部气过水声定位,564人(58.93%)回抽胃内容物定位,而AACN推荐的最简单直观的胃管刻度确定法和pH值测试法,仅393人(41.06%)和31人(3.24%)总是使用。不同医院级别、是否ICU护士选择胃管刻度确定法及不同医院级别、护龄、学历、职称、是否专科护士选择pH值测试法存在差异(P<0.05,P<0.01)。结论管饲期间护士胃管定位方法的选择与实践警报推荐存在一定差距。护士应转变观念,加强相关理论知识学习和进行积极地循证护理实践,以更准确有效地实施临床护理操作。
