Intensive livestock and poultry farming in China largely relied on the use of in-feed antibiotics until July 2020.The consequences of antibiotic overuse in animal feed include accumulation in animal products and the d...Intensive livestock and poultry farming in China largely relied on the use of in-feed antibiotics until July 2020.The consequences of antibiotic overuse in animal feed include accumulation in animal products and the development of bacterial antibiotic resistance,both of which threaten food safety and human health.China has now completely banned the circulation of commercial feed containing growth-promoting drug additives(except Chinese herbal medicine).Therefore,alternatives to in-feed antibiotics in animal production are greatly needed.Natural phenolic compounds(NPCs)exist widely in plants and are non-toxic,nonpolluting,highly reproducible,and leave little residue.Many natural flavonoids,phenolic acids,lignans,and stilbenes have polyphenol chemical structures and exhibit great potential as alternatives to antibiotics.In this review we delineate the characteristics of plant-derived NPCs and summarize their current applications as alternatives to in-feed antibiotics,aiming to provide new strategies for antibiotic-free feeding and promote the development of more sustainable animal husbandry practices.展开更多
基金supported by the National Key Research and Development Program of China(2022YFD1300403)the National Natural Science Foundation of China(32130099)+7 种基金the“Shen Nong Scholar Funding of Hunan Agricultural University”the“Changsha Municipal Natural Science Foundation(kq2014068)”the“Hunan Natural Science Foundation(2021JJ40233)”the“Science and Technology Innovation Program of Hunan Province(2021RC3090)”the“Open Project Program of Key Laboratory of Feed Biotechnologythe Ministry of Agriculture and Rural Affairs of the People’s Republic of China”the“Earmarked Fund for China Agriculture Research System(CARS-35)”the“China Agriculture Research System of MOF and MARA”。
文摘Intensive livestock and poultry farming in China largely relied on the use of in-feed antibiotics until July 2020.The consequences of antibiotic overuse in animal feed include accumulation in animal products and the development of bacterial antibiotic resistance,both of which threaten food safety and human health.China has now completely banned the circulation of commercial feed containing growth-promoting drug additives(except Chinese herbal medicine).Therefore,alternatives to in-feed antibiotics in animal production are greatly needed.Natural phenolic compounds(NPCs)exist widely in plants and are non-toxic,nonpolluting,highly reproducible,and leave little residue.Many natural flavonoids,phenolic acids,lignans,and stilbenes have polyphenol chemical structures and exhibit great potential as alternatives to antibiotics.In this review we delineate the characteristics of plant-derived NPCs and summarize their current applications as alternatives to in-feed antibiotics,aiming to provide new strategies for antibiotic-free feeding and promote the development of more sustainable animal husbandry practices.
