Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain. With the increase of membrane proteins on soma and in...Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain. With the increase of membrane proteins on soma and injured site neurons, the negatively charged sialic acids bind to the external domains of membrane proteins, resulting in an increase of this charge. We therefore speculate that the electrophoretic velocity of injured neurons may be faster than non-injured neurons. The present study established rat models of neuropathic pain via chronic constriction injury. Results of the cell electrophoresis test revealed that the electrophoretic velocity of injured neuronal cells was faster than that of non-injured （control） cells. We then treated cells with divalent cations of Ca2＋ and organic compounds with positive charges, polylysine to counteract the negatively charged sialic acids, or neuraminidase to specifically remove sialic acids from the membrane surface of injured neurons. All three treatments significantly reduced the electrophoretic velocity of injured neuronal cells. These findings suggest that enhanced sialic acids on injured neurons may accelerate the electrophoretic velocity of injured neurons.展开更多
This article expounds the significance of sustainable development in the existence and progress of mankind and the policies that China should adopt. It points out that the ecology, and resource and environmental scien...This article expounds the significance of sustainable development in the existence and progress of mankind and the policies that China should adopt. It points out that the ecology, and resource and environmental sciences are the core in the study of sustainable development. The author analyzes the achievements, contributions and problems in the studies of resources, ecology and the environment, which have been carried out at the Chinese Academy of Sciences. He also puts forward tentative ideas and suggestions in deepening the reform of systems, speeding up the construction of research bases, laying stress on regional features in study, promoting the integrating of disciplines, and giving play to the overall advantages of the Academy.展开更多
Post-incident studies provide direct and valuable information to further the scientific understanding of Wildland-Urban Interface(WUI)fires.Most post-incident studies involve data collection in the field(i.e.a“resear...Post-incident studies provide direct and valuable information to further the scientific understanding of Wildland-Urban Interface(WUI)fires.Most post-incident studies involve data collection in the field(i.e.a“research field deployment”).In this review,technical reports of post-incident studies for WUI fire and other natural disasters were analyzed and professionals directly involved in WUI fire research field deployments were interviewed.The goal of this review is to provide a resource for future WUI studies regarding the development of safe and effective fieldwork procedures,the collection and integration of accurate and relevant data,and the establishment of practical lessons learned.Three main stages of WUI fire post-incident studies are identified and described in detail.Data collection methodologies,data attributes,logistical practices and lessons-learned were compiled from various past studies and are presented here in the context of application to WUI fire.展开更多
The environment structure of natural nidi and epidemic areas of hemorrhagic fever with renal syndrome (HFRS) possesses characteristics of topography, hydrology, climate, soil, vegetation, and animals. The natural nidi...The environment structure of natural nidi and epidemic areas of hemorrhagic fever with renal syndrome (HFRS) possesses characteristics of topography, hydrology, climate, soil, vegetation, and animals. The natural nidi and epidemic areas of HFRS are distributed mainly in plain and hilly regions under 500 meters above the sea level; in plentiful-water zones and transitional zones; in temperate zone and subtropical zone of the eastern monsoon region; in the abundant-aluminum soil region and the sial soil region; in the eastern China damp forest region (agricultural districts and northeast forest districts); in the eastern Asia dampness-prefering animal geographic region. Apodemus agrarius and Rattus norvegicus are the thriving animal population, predominant species or common species as well as the main reservoir hosts and sources of infection in the natural nidi and epidemic areas of HFRS.展开更多
基金supported by the Natural Science Foundation of Shanxi Province in China,No.2012011042-3
文摘Peripheral nerve injury has been shown to result in ectopic spontaneous discharges on soma and injured sites of sensory neurons, thereby inducing neuropathic pain. With the increase of membrane proteins on soma and injured site neurons, the negatively charged sialic acids bind to the external domains of membrane proteins, resulting in an increase of this charge. We therefore speculate that the electrophoretic velocity of injured neurons may be faster than non-injured neurons. The present study established rat models of neuropathic pain via chronic constriction injury. Results of the cell electrophoresis test revealed that the electrophoretic velocity of injured neuronal cells was faster than that of non-injured （control） cells. We then treated cells with divalent cations of Ca2＋ and organic compounds with positive charges, polylysine to counteract the negatively charged sialic acids, or neuraminidase to specifically remove sialic acids from the membrane surface of injured neurons. All three treatments significantly reduced the electrophoretic velocity of injured neuronal cells. These findings suggest that enhanced sialic acids on injured neurons may accelerate the electrophoretic velocity of injured neurons.
文摘This article expounds the significance of sustainable development in the existence and progress of mankind and the policies that China should adopt. It points out that the ecology, and resource and environmental sciences are the core in the study of sustainable development. The author analyzes the achievements, contributions and problems in the studies of resources, ecology and the environment, which have been carried out at the Chinese Academy of Sciences. He also puts forward tentative ideas and suggestions in deepening the reform of systems, speeding up the construction of research bases, laying stress on regional features in study, promoting the integrating of disciplines, and giving play to the overall advantages of the Academy.
文摘Post-incident studies provide direct and valuable information to further the scientific understanding of Wildland-Urban Interface(WUI)fires.Most post-incident studies involve data collection in the field(i.e.a“research field deployment”).In this review,technical reports of post-incident studies for WUI fire and other natural disasters were analyzed and professionals directly involved in WUI fire research field deployments were interviewed.The goal of this review is to provide a resource for future WUI studies regarding the development of safe and effective fieldwork procedures,the collection and integration of accurate and relevant data,and the establishment of practical lessons learned.Three main stages of WUI fire post-incident studies are identified and described in detail.Data collection methodologies,data attributes,logistical practices and lessons-learned were compiled from various past studies and are presented here in the context of application to WUI fire.
文摘The environment structure of natural nidi and epidemic areas of hemorrhagic fever with renal syndrome (HFRS) possesses characteristics of topography, hydrology, climate, soil, vegetation, and animals. The natural nidi and epidemic areas of HFRS are distributed mainly in plain and hilly regions under 500 meters above the sea level; in plentiful-water zones and transitional zones; in temperate zone and subtropical zone of the eastern monsoon region; in the abundant-aluminum soil region and the sial soil region; in the eastern China damp forest region (agricultural districts and northeast forest districts); in the eastern Asia dampness-prefering animal geographic region. Apodemus agrarius and Rattus norvegicus are the thriving animal population, predominant species or common species as well as the main reservoir hosts and sources of infection in the natural nidi and epidemic areas of HFRS.
