Objective:To determine if there was any difference in SpO2 readings during exchange blood transfusion(EBT).Methods:A prospective cross-sectional study of neonates with severe neonatal jaundice requiring EBT was conduc...Objective:To determine if there was any difference in SpO2 readings during exchange blood transfusion(EBT).Methods:A prospective cross-sectional study of neonates with severe neonatal jaundice requiring EBT was conducted.Oxygen saturation was recorded before,immediately and 15 minutes after EBT by using a pulse oximeter.Results:This study included 30 neonates with 20 males and 10 females.The age ranged from 1 to 12 days with a mean of(5.4±2.9)days.Pre-EBT SpO2 ranged from 90%to 98%with a mean value of(94.3±2.2)%;SpO2 in the end of EBT ranged from 85%to 99%with a mean value of(94.1±3.2)%;SpO2 at 15 minutes after EBT ranged from 77%to 99%with a mean value of(94.8±4.1)%.There was no significant difference between SpO2 values at onset of EBT and either immediately or 15 minutes after EBT(P=0.770 and 0.422,respectively).SpO2 showed no significant difference between neonates who were infused with blood of different storage times(<24 h or≥24 h)at the onset of EBT(P=0.584),immediately(P>0.999)and 15 minutes after EBT(P=0.887).Besides,SpO2 values were compariable in neonates with hematocrit<45%or≥45%at the onset of EBT(P=0.284),immediately(P=0.118)and 15 minutes after EBT(P=0.868).Conclusions:EBT does not affect SpO2 in neonates.展开更多
目的回顾性评价高球浆比全血置换联合茵栀黄口服液治疗重度Rh血型不合新生儿溶血病(hemolyticdisease of newborn,HDN)的疗效。方法选择2011年4月—2012年12月确诊的Rh血型不合HDN 15例,给予高球浆比全血置换联合茵栀黄口服液治疗,监测...目的回顾性评价高球浆比全血置换联合茵栀黄口服液治疗重度Rh血型不合新生儿溶血病(hemolyticdisease of newborn,HDN)的疗效。方法选择2011年4月—2012年12月确诊的Rh血型不合HDN 15例,给予高球浆比全血置换联合茵栀黄口服液治疗,监测治疗前后胆红素、总胆红素/白蛋白(B/A)、血常规、血生化指标的变化,评价安全性及转归情况。结果本组治疗后血清总胆红素(TBIL)、间接胆红素(IBIL)、直接胆红素(DBIL)、总胆红素/白蛋白(B/A)以及白细胞和血小板计数、Ca2+均较治疗前下降,差异均有统计学意义(P<0.05,P<0.01)。3例出现轻度腹泻,给予药物减量后好转;5例出现代谢性酸中毒,随即给予纠正。临床痊愈出院14例,1例放弃继续治疗。结论高球浆比全血置换联合茵栀黄口服液治疗Rh血型不合HDN具有很好效果,且安全性较高。展开更多
文摘Objective:To determine if there was any difference in SpO2 readings during exchange blood transfusion(EBT).Methods:A prospective cross-sectional study of neonates with severe neonatal jaundice requiring EBT was conducted.Oxygen saturation was recorded before,immediately and 15 minutes after EBT by using a pulse oximeter.Results:This study included 30 neonates with 20 males and 10 females.The age ranged from 1 to 12 days with a mean of(5.4±2.9)days.Pre-EBT SpO2 ranged from 90%to 98%with a mean value of(94.3±2.2)%;SpO2 in the end of EBT ranged from 85%to 99%with a mean value of(94.1±3.2)%;SpO2 at 15 minutes after EBT ranged from 77%to 99%with a mean value of(94.8±4.1)%.There was no significant difference between SpO2 values at onset of EBT and either immediately or 15 minutes after EBT(P=0.770 and 0.422,respectively).SpO2 showed no significant difference between neonates who were infused with blood of different storage times(<24 h or≥24 h)at the onset of EBT(P=0.584),immediately(P>0.999)and 15 minutes after EBT(P=0.887).Besides,SpO2 values were compariable in neonates with hematocrit<45%or≥45%at the onset of EBT(P=0.284),immediately(P=0.118)and 15 minutes after EBT(P=0.868).Conclusions:EBT does not affect SpO2 in neonates.
文摘目的回顾性评价高球浆比全血置换联合茵栀黄口服液治疗重度Rh血型不合新生儿溶血病(hemolyticdisease of newborn,HDN)的疗效。方法选择2011年4月—2012年12月确诊的Rh血型不合HDN 15例,给予高球浆比全血置换联合茵栀黄口服液治疗,监测治疗前后胆红素、总胆红素/白蛋白(B/A)、血常规、血生化指标的变化,评价安全性及转归情况。结果本组治疗后血清总胆红素(TBIL)、间接胆红素(IBIL)、直接胆红素(DBIL)、总胆红素/白蛋白(B/A)以及白细胞和血小板计数、Ca2+均较治疗前下降,差异均有统计学意义(P<0.05,P<0.01)。3例出现轻度腹泻,给予药物减量后好转;5例出现代谢性酸中毒,随即给予纠正。临床痊愈出院14例,1例放弃继续治疗。结论高球浆比全血置换联合茵栀黄口服液治疗Rh血型不合HDN具有很好效果,且安全性较高。
