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On Designs of Decentralized Reputation Management for Permissioned Blockchain Networks
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作者 Jinyu Chen Long Shi +2 位作者 Qisheng Huang Taotao Wang Daojing He 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期1755-1773,共19页
In permissioned blockchain networks,the Proof of Authority(PoA)consensus,which uses the election of authorized nodes to validate transactions and blocks,has beenwidely advocated thanks to its high transaction throughp... In permissioned blockchain networks,the Proof of Authority(PoA)consensus,which uses the election of authorized nodes to validate transactions and blocks,has beenwidely advocated thanks to its high transaction throughput and fault tolerance.However,PoA suffers from the drawback of centralization dominated by a limited number of authorized nodes and the lack of anonymity due to the round-robin block proposal mechanism.As a result,traditional PoA is vulnerable to a single point of failure that compromises the security of the blockchain network.To address these issues,we propose a novel decentralized reputation management mechanism for permissioned blockchain networks to enhance security,promote liveness,and mitigate centralization while retaining the same throughput as traditional PoA.This paper aims to design an off-chain reputation evaluation and an on-chain reputation-aided consensus.First,we evaluate the nodes’reputation in the context of the blockchain networks and make the reputation globally verifiable through smart contracts.Second,building upon traditional PoA,we propose a reputation-aided PoA(rPoA)consensus to enhance securitywithout sacrificing throughput.In particular,rPoA can incentivize nodes to autonomously form committees based on reputation authority,which prevents block generation from being tracked through the randomness of reputation variation.Moreover,we develop a reputation-aided fork-choice rule for rPoA to promote the network’s liveness.Finally,experimental results show that the proposed rPoA achieves higher security performance while retaining transaction throughput compared to traditional PoA. 展开更多
关键词 Blockchain reputation management POA THROUGHPUT SECURITY DECENTRALIZATION
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Resource management at the network edge for federated learning
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作者 Silvana Trindade Luiz F.Bittencourt Nelson L.S.da Fonseca 《Digital Communications and Networks》 SCIE CSCD 2024年第3期765-782,共18页
Federated learning has been explored as a promising solution for training machine learning models at the network edge,without sharing private user data.With limited resources at the edge,new solutions must be develope... Federated learning has been explored as a promising solution for training machine learning models at the network edge,without sharing private user data.With limited resources at the edge,new solutions must be developed to leverage the software and hardware resources as the existing solutions did not focus on resource management for network edge,specially for federated learning.In this paper,we describe the recent work on resource manage-ment at the edge and explore the challenges and future directions to allow the execution of federated learning at the edge.Problems such as the discovery of resources,deployment,load balancing,migration,and energy effi-ciency are discussed in the paper. 展开更多
关键词 Resource management Edge computing Federated learning Machine learning
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A Self-Attention Based Dynamic Resource Management for Satellite-Terrestrial Networks
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作者 Lin Tianhao Luo Zhiyong 《China Communications》 SCIE CSCD 2024年第4期136-150,共15页
The satellite-terrestrial networks possess the ability to transcend geographical constraints inherent in traditional communication networks,enabling global coverage and offering users ubiquitous computing power suppor... The satellite-terrestrial networks possess the ability to transcend geographical constraints inherent in traditional communication networks,enabling global coverage and offering users ubiquitous computing power support,which is an important development direction of future communications.In this paper,we take into account a multi-scenario network model under the coverage of low earth orbit(LEO)satellite,which can provide computing resources to users in faraway areas to improve task processing efficiency.However,LEO satellites experience limitations in computing and communication resources and the channels are time-varying and complex,which makes the extraction of state information a daunting task.Therefore,we explore the dynamic resource management issue pertaining to joint computing,communication resource allocation and power control for multi-access edge computing(MEC).In order to tackle this formidable issue,we undertake the task of transforming the issue into a Markov decision process(MDP)problem and propose the self-attention based dynamic resource management(SABDRM)algorithm,which effectively extracts state information features to enhance the training process.Simulation results show that the proposed algorithm is capable of effectively reducing the long-term average delay and energy consumption of the tasks. 展开更多
关键词 mobile edge computing resource management satellite-terrestrial networks self-attention
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Sensing-Assisted Accurate and Fast Beam Management for Cellular-Connected mmWave UAV Network
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作者 Cui Yanpeng Zhang Qixun +4 位作者 Feng Zhiyong Qin Wen Zhou Ying Wei Zhiqing Zhang Ping 《China Communications》 SCIE CSCD 2024年第6期271-289,共19页
Beam management,including initial access(IA)and beam tracking,is essential to the millimeter-wave Unmanned Aerial Vehicle(UAV)network.However,the conventional communicationonly and feedback-based schemes suffer a high... Beam management,including initial access(IA)and beam tracking,is essential to the millimeter-wave Unmanned Aerial Vehicle(UAV)network.However,the conventional communicationonly and feedback-based schemes suffer a high delay and low accuracy of beam alignment,since they only enable the receiver to passively“hear”the information of the transmitter from the radio domain.This paper presents a novel sensing-assisted beam management approach,the first solution that fully utilizes the information from the visual domain to improve communication performance.We employ both integrated sensing and communication and computer vision techniques and design an extended Kalman filtering method for beam tracking and prediction.Besides,we also propose a novel dual identity association solution to distinguish multiple UAVs in dynamic environments.Real-world experiments and numerical results show that the proposed solution outperforms the conventional methods in IA delay,association accuracy,tracking error,and communication performance. 展开更多
关键词 beam management integrated sensing and communication UAV communication
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Digital Twins for Engineering Asset Management:Synthesis,Analytical Framework,and Future Directions
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作者 Yongkui Li Qinyue Wang +3 位作者 Xiyu Pan Jian Zuo Jinying Xu Yilong Han 《Engineering》 SCIE EI CAS CSCD 2024年第10期261-275,共15页
Effective engineering asset management(EAM)is critical to economic development and improving livability in society,but its complexity often impedes optimal asset functionalities.Digital twins(DTs)could revolutionize t... Effective engineering asset management(EAM)is critical to economic development and improving livability in society,but its complexity often impedes optimal asset functionalities.Digital twins(DTs)could revolutionize the EAM paradigm by bidirectionally linking the physical and digital worlds in real time.There is great industrial and academic interest in DTs for EAM.However,previous review studies have predominately focused on technical aspects using limited life-cycle perspectives,failing to holistically synthesize DTs for EAM from the managerial point of view.Based on a systematic literature review,we introduce an analytical framework for describing DTs for EAM,which encompasses three levels:DT 1.0 for technical EAM,DT 2.0 for technical-human EAM,and DT 3.0 for technical-environmental EAM.Using this framework,we identify what is known,what is unknown,and future directions at each level.DT 1.0 addresses issues of asset quality,progress,and cost management,generating technical value.It lacks multi-objective self-adaptive EAM,however,and suffers from high application cost.It is imperative to enable closed-loop EAM in order to provide various functional services with affordable DT 1.0.DT 2.0 accommodates issues of human-machine symbiosis,safety,and flexibility management,generating managerial value beyond the technical performance improvement of engineering assets.However,DT 2.0 currently lacks the automation and security of human-machine interactions and the managerial value related to humans is not prominent enough.Future research needs to align technical and managerial value with highly automated and secure DT 2.0.DT 3.0 covers issues of participatory governance,organization management,sustainable development,and resilience enhancement,generating macro social value.Yet it suffers from organizational fragmentation and can only address limited social governance issues.Numerous research opportunities exist to coordinate different stakeholders.Similarly,future research opportunities exist to develop DT 3.0 in a more open and complex system. 展开更多
关键词 Engineering asset management Digital twin Socio-technical theory Structureprocessoutcome Literature review
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Security Monitoring and Management for the Network Services in the Orchestration of SDN-NFV Environment Using Machine Learning Techniques
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作者 Nasser Alshammari Shumaila Shahzadi +7 位作者 Saad Awadh Alanazi Shahid Naseem Muhammad Anwar Madallah Alruwaili Muhammad Rizwan Abid Omar Alruwaili Ahmed Alsayat Fahad Ahmad 《Computer Systems Science & Engineering》 2024年第2期363-394,共32页
Software Defined Network(SDN)and Network Function Virtualization(NFV)technology promote several benefits to network operators,including reduced maintenance costs,increased network operational performance,simplified ne... Software Defined Network(SDN)and Network Function Virtualization(NFV)technology promote several benefits to network operators,including reduced maintenance costs,increased network operational performance,simplified network lifecycle,and policies management.Network vulnerabilities try to modify services provided by Network Function Virtualization MANagement and Orchestration(NFV MANO),and malicious attacks in different scenarios disrupt the NFV Orchestrator(NFVO)and Virtualized Infrastructure Manager(VIM)lifecycle management related to network services or individual Virtualized Network Function(VNF).This paper proposes an anomaly detection mechanism that monitors threats in NFV MANO and manages promptly and adaptively to implement and handle security functions in order to enhance the quality of experience for end users.An anomaly detector investigates these identified risks and provides secure network services.It enables virtual network security functions and identifies anomalies in Kubernetes(a cloud-based platform).For training and testing purpose of the proposed approach,an intrusion-containing dataset is used that hold multiple malicious activities like a Smurf,Neptune,Teardrop,Pod,Land,IPsweep,etc.,categorized as Probing(Prob),Denial of Service(DoS),User to Root(U2R),and Remote to User(R2L)attacks.An anomaly detector is anticipated with the capabilities of a Machine Learning(ML)technique,making use of supervised learning techniques like Logistic Regression(LR),Support Vector Machine(SVM),Random Forest(RF),Naïve Bayes(NB),and Extreme Gradient Boosting(XGBoost).The proposed framework has been evaluated by deploying the identified ML algorithm on a Jupyter notebook in Kubeflow to simulate Kubernetes for validation purposes.RF classifier has shown better outcomes(99.90%accuracy)than other classifiers in detecting anomalies/intrusions in the containerized environment. 展开更多
关键词 Software defined network network function virtualization network function virtualization management and orchestration virtual infrastructure manager virtual network function Kubernetes Kubectl artificial intelligence machine learning
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A theoretical framework for improved fire suppression by linking management models with smart early fire detection and suppression technologies
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作者 Li Meng Jim O’Hehir +2 位作者 Jing Gao Stefan Peters Anthony Hay 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第5期1-13,共13页
Bushfires are devastating to forest managers,owners,residents,and the natural environment.Recent tech-nological advances indicate a potential for faster response times in terms of detecting and suppressing fires.Howev... Bushfires are devastating to forest managers,owners,residents,and the natural environment.Recent tech-nological advances indicate a potential for faster response times in terms of detecting and suppressing fires.However,to date,all these technologies have been applied in isola-tion.This paper introduces the latest fire detection and sup-pression technologies from ground to space.An operations research method was used to assemble these technologies into a theoretical framework for fire detection and suppres-sion.The framework harnesses the advantages of satellite-based,drone,sensor,and human reporting technologies as well as image processing and artificial intelligence machine learning.The study concludes that,if a system is designed to maximise the use of available technologies and carefully adopts them through complementary arrangements,a fire detection and resource suppression system can achieve the ultimate aim:to reduce the risk of fire hazards and the dam-age they may cause. 展开更多
关键词 Forest fire Resource suppression Smart fire detection and suppression system Forest fire management Holistic system
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Development of a Framework for Equipment Health Management in the Mining Industries in Zambia
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作者 Tobias Njobvu Terence Malama 《World Journal of Engineering and Technology》 2024年第3期665-694,共30页
The Zambian mining industry is crucial to the national economy but struggles with inconsistent equipment maintenance practices. This study developed an Equipment Maintenance Management Framework (EMMF) tailored to the... The Zambian mining industry is crucial to the national economy but struggles with inconsistent equipment maintenance practices. This study developed an Equipment Maintenance Management Framework (EMMF) tailored to the industry’s needs. Using surveys, interviews, and on-site visits at eight major mining companies, we identified significant variations in maintenance strategies, CMMS usage, and reliability engineering. The EMMF prioritizes predictive maintenance, efficient CMMS implementation, ongoing training, and robust reliability engineering to shift from reactive to proactive maintenance. We recommend adopting continuous improvement practices and data-driven decision-making based on performance metrics, with a phased EMMF implementation aligning maintenance with strategic business objectives. This framework is poised to enhance operational efficiency, equipment reliability, and safety, fostering sustainable growth in the Zambian mining sector. 展开更多
关键词 Equipment Maintenance management Framework (EMMF) Computerized Maintenance management System (CMMS) Preventive Maintenance Predictive Maintenance Data Analytics
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Contribution to Computer Waste Management:Knowledge of the Regulatory Framework by Industry Stakeholders in Guinea
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作者 Fatoumata Sylla Ansoumane Sakouvogui +3 位作者 Saran Camara Mamadou Sanoussy Camara Mamadou Kabirou Bah Alpha Issiaga Diallo 《Journal of Environmental Science and Engineering(A)》 CAS 2024年第5期156-164,共9页
In African countries,regulations on the management of WTE(Waste from Information Technology Equipment)are non-existent or sometimes insufficient,if they exist.This study shows how to mention waste from information tec... In African countries,regulations on the management of WTE(Waste from Information Technology Equipment)are non-existent or sometimes insufficient,if they exist.This study shows how to mention waste from information technology equipment in a country that does not have a regulatory legislative framework or organized management channels.A methodological approach based on documentary research and semi-directed interviews was adopted in this work.The results showed that 54.55%of institutional managers are unaware of the existence of regulations for the management of WTE,both at the national and international levels;72.72%of these managers do not have a specific implementing text for this management;72.73%of institutions have adopted an acquisition policy based on the needs of workers and 81.82%of institutions store WTE in warehouses.Relations with waste collection SMEs(Small and Midsize Enterprises),especially for IT equipment,are limited for 72.73%of institutions.In terms of improving the capacity to manage WEEE(Waste Electrical and Electronic Equipment),90.91%of institutions do not offer training or awareness raising.Overall,no significant indicators are in place to assess WEEE management in institutions,which reflects a lack of commitment and awareness among institutional managers.In addition,there are no financial means for ecological and sustainable management.Although 27.27%of managers are aware of the dangers to human health and the environment related to IT equipment,they are often unaware of the harmful consequences of abandoning it in nature. 展开更多
关键词 WASTE IT equipment legal frameworks REGULATIONS informal management
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Sustainable Wetland Management Using the Kunming-Montreal Global Biodiversity Framework as a Guide in the Sierra Leone Case
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作者 Changming Yang Aloysious Kingsley Suleiman Yi Lang 《Journal of Geoscience and Environment Protection》 2024年第3期1-15,共15页
The Sustainable Wetland Management adopted for this study depicts that, the identification of drivers and impacts is needed first, in other to get a clearer roadmap, after which the Kunming-Montreal Global Biodiversit... The Sustainable Wetland Management adopted for this study depicts that, the identification of drivers and impacts is needed first, in other to get a clearer roadmap, after which the Kunming-Montreal Global Biodiversity Framework would come into play to serve as a pathway for Sustainability. The study evaluates how Sierra Leone might implement the Framework’s proposed strategies in National Wetland Management. As a result, the research tried to thoroughly examine the factors that contribute to wetland degradation as well as the effects they have on the people who live nearby. The purposive sampling method was used to administer 385 structured questionnaires to inhabitants. The data was then processed in an Excel spreadsheet. Microsoft Publisher was used to draw the framework and a descriptive analysis was done. Results indicated that;the majority of the inhabitants of Aberdeen Creek are traders/self-employed, furthermore, the majority chose the place because it’s less expensive and nearer to the workplace, settlement expansion and pollution are the two most common degrading activities, while flooding and health-related issues are some of the consequences, and the Kunming-Montreal Global Biodiversity Framework is regarded to be a perfect tool for wetland management. It was concluded that to accomplish the objectives in the framework, it is necessary to have both political and social will. Satellite data and water quality research are further needed to validate the report. 展开更多
关键词 Kunming-Montreal Wetland management URBANIZATION BIODIVERSITY Aberdeen Creek
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Development of a Sports Safety Promotion Framework Based on KABP Theory and 4M Management
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作者 Duoyang Hu Di Mu 《Journal of Contemporary Educational Research》 2024年第7期331-334,共4页
This study explores the significance,current research landscape,and conceptualization of sports safety promotion.Safety in sports is fundamental to youth physical activities,and an excessive focus on or neglect of saf... This study explores the significance,current research landscape,and conceptualization of sports safety promotion.Safety in sports is fundamental to youth physical activities,and an excessive focus on or neglect of safety is unwarranted.Globally,numerous countries have extensively researched sports safety promotion and implemented diverse strategies.Drawing from KABP(Knowledge,Attitude,Behavior,Practice)theory and 4M(Man,Machine,Medium,Management)management,this paper presents a conceptual framework for sports safety promotion.It integrates these theories to devise a comprehensive accident prevention model within a sports safety promotion system.The framework prioritizes enhancing students’safety literacy and underscores the practical application of safety knowledge and skills in simulated sports settings following structured safety education.It aims to enhance students’competency and proficiency in averting sports-related injuries. 展开更多
关键词 Knowledge Attitude Behavior Practice theory Man Machine Medium management management Sports safety promotion Youth sports safety
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Track Bed Total Route Evaluation for Track Renewals&Asset Management“A Network Rail Perspective”
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作者 Peter Musgrave 《Journal of Traffic and Transportation Engineering》 2024年第5期238-247,共10页
Over the last 10 years there have been significant developments and improvements in the understanding of railway track bed in the UK and its relationship and impact on track quality,ballast life and maintenance follow... Over the last 10 years there have been significant developments and improvements in the understanding of railway track bed in the UK and its relationship and impact on track quality,ballast life and maintenance following track renewals.This paper aims to describe the process adopted by Network Rail for track bed investigation and design which offers Network Rail optimum design solutions and value for money from an investigation and construction perspective,balancing design with possession availability to maximise construction output.It also describes innovative investigation and construction techniques that have been developed over the last 5 years maximising the use of rail mounted asset condition data collection systems which run at line speed,allowing targeted investigations and in some case removing the requirements for physical site investigation.It also allows Network Rail to predict sections of track bed which may be affected by line speed increases which would cause the track bed to fail prematurely or,retain its ability to maintain good track geometry post line speed increase.These problems can manifest themselves as stiffness related problems such as critical velocity issues(surface wave velocity,Rayleigh Wave velocity)or,sub-grade erosion resulting in high rates of deterioration in the vertical track geometry.The paper also describes the development and installation process for Enhanced Axial Micropiles to address stiffness related track bed problems whilst leaving the track in-situ a technique which is new to the UK railways. 展开更多
关键词 Track bed data analysis route evaluation asset management track bed piling and design
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Personal Thermal Management by Radiative Cooling and Heating 被引量:2
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作者 Shidong Xue Guanghan Huang +3 位作者 Qing Chen Xungai Wang Jintu Fan Dahua Shou 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第8期225-267,共43页
Maintaining thermal comfort within the human body is crucial for optimal health and overall well-being.By merely broadening the setpoint of indoor temperatures,we could significantly slash energy usage in building hea... Maintaining thermal comfort within the human body is crucial for optimal health and overall well-being.By merely broadening the setpoint of indoor temperatures,we could significantly slash energy usage in building heating,ventilation,and air-conditioning systems.In recent years,there has been a surge in advancements in personal thermal management(PTM),aiming to regulate heat and moisture transfer within our immediate surroundings,clothing,and skin.The advent of PTM is driven by the rapid development in nano/micro-materials and energy science and engineering.An emerging research area in PTM is personal radiative thermal management(PRTM),which demonstrates immense potential with its high radiative heat transfer efficiency and ease of regulation.However,it is less taken into account in traditional textiles,and there currently lies a gap in our knowledge and understanding of PRTM.In this review,we aim to present a thorough analysis of advanced textile materials and technologies for PRTM.Specifically,we will introduce and discuss the underlying radiation heat transfer mechanisms,fabrication methods of textiles,and various indoor/outdoor applications in light of their different regulation functionalities,including radiative cooling,radiative heating,and dual-mode thermoregulation.Furthermore,we will shine a light on the current hurdles,propose potential strategies,and delve into future technology trends for PRTM with an emphasis on functionalities and applications. 展开更多
关键词 Personal thermal management Radiative cooling and heating Thermal comfort Dynamic thermoregulation
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Patient satisfaction and follow-up adherence to glaucoma case management clinic in China 被引量:1
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作者 Hao Lin Hu-Jie Lu +3 位作者 Wen-Zhe Zhou Shu-Shu Zuo Yan-Yan Chen Shao-Dan Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第1期73-81,共9页
AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a tota... AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a total of 119 patients completed a Patient Satisfaction Questionnaire-18 and a sociodemographic questionnaire.Clinical data was obtained from the case management system.Follow-up adherence was defined as completing each follow-up within±30d of the scheduled time set by ophthalmologists during the study period.RESULTS:Average satisfaction scored 78.65±7,with an average of 4.39±0.58 across the seven dimensions.Age negatively correlated with satisfaction(P=0.008),whilst patients with follow-up duration of 2 or more years reported higher satisfaction(P=0.045).Multivariate logistics regression analysis revealed that longer follow-up durations were associated with lower follow-up adherence(OR=0.97,95%CI,0.95-1.00,P=0.044).Additionally,patients with suspected glaucoma(OR=2.72,95%CI,1.03-7.20,P=0.044)and those with an annual income over 100000 Chinese yuan demonstrated higher adherence(OR=5.57,95%CI,1.00-30.89,P=0.049).CONCLUSION:The case management model proves effective for glaucoma patients,with positive adherence rates.The implementation of this model can be optimized in the future based on the identified factors and extended to glaucoma patients in more hospitals. 展开更多
关键词 GLAUCOMA patient satisfaction follow-up adherence case management
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Managing the surge:A comprehensive review of the entire disposal framework for retired lithium-ion batteries from electric vehicles 被引量:2
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作者 Ruohan Guo Feng Wang +2 位作者 M.Akbar Rhamdhani Yiming Xu Weixiang Shen 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第5期648-680,共33页
Anticipating the imminent surge of retired lithium-ion batteries(R-LIBs)from electric vehicles,the need for safe,cost-effective and environmentally friendly disposal technologies has escalated.This paper seeks to offe... Anticipating the imminent surge of retired lithium-ion batteries(R-LIBs)from electric vehicles,the need for safe,cost-effective and environmentally friendly disposal technologies has escalated.This paper seeks to offer a comprehensive overview of the entire disposal framework for R-LIBs,encompassing a broad spectrum of activities,including screening,repurposing and recycling.Firstly,we delve deeply into a thorough examination of current screening technologies,shifting the focus from a mere enumeration of screening methods to the exploration of the strategies for enhancing screening efficiency.Secondly,we outline battery repurposing with associated key factors,summarizing stationary applications and sizing methods for R-LIBs in their second life.A particular light is shed on available reconditioning solutions,demonstrating their great potential in facilitating battery safety and lifetime in repurposing scenarios and identifying their techno-economic issues.In the realm of battery recycling,we present an extensive survey of pre-treatment options and subsequent material recovery technologies.Particularly,we introduce several global leading recyclers to illustrate their industrial processes and technical intricacies.Furthermore,relevant challenges and evolving trends are investigated in pursuit of a sustainable end-of-life management and disposal framework.We hope that this study can serve as a valuable resource for researchers,industry professionals and policymakers in this field,ultimately facilitating the adoption of proper disposal practices. 展开更多
关键词 Lithium-ion battery Battery reproposing and recycling Miaieiials recovery technologies Techno-economic issues End-of-life management Disposal framework
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Overview of the immunological mechanisms in hepatitis B virus reactivation:Implications for disease progression and management strategies 被引量:1
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作者 Hui Ma Qing-Zhu Yan +2 位作者 Jing-Ru Ma Dong-Fu Li Jun-Ling Yang 《World Journal of Gastroenterology》 SCIE CAS 2024年第10期1295-1312,共18页
Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and manageme... Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and management.It delves into host immune responses and reactivation’s delicate balance,spanning innate and adaptive immunity.Viral factors’disruption of this balance,as are interac-tions between viral antigens,immune cells,cytokine networks,and immune checkpoint pathways,are examined.Notably,the roles of T cells,natural killer cells,and antigen-presenting cells are discussed,highlighting their influence on disease progression.HBV reactivation’s impact on disease severity,hepatic flares,liver fibrosis progression,and hepatocellular carcinoma is detailed.Management strategies,including anti-viral and immunomodulatory approaches,are critically analyzed.The role of prophylactic anti-viral therapy during immunosuppressive treatments is explored alongside novel immunotherapeutic interventions to restore immune control and prevent reactivation.In conclusion,this compre-hensive review furnishes a holistic view of the immunological mechanisms that propel HBV reactivation.With a dedicated focus on understanding its implic-ations for disease progression and the prospects of efficient management stra-tegies,this article contributes significantly to the knowledge base.The more profound insights into the intricate interactions between viral elements and the immune system will inform evidence-based approaches,ultimately enhancing disease management and elevating patient outcomes.The dynamic landscape of management strategies is critically scrutinized,spanning anti-viral and immunomodulatory approaches.The role of prophylactic anti-viral therapy in preventing reactivation during immunosuppressive treatments and the potential of innovative immunotherapeutic interventions to restore immune control and proactively deter reactivation. 展开更多
关键词 Hepatitis B virus reactivation Immunological mechanisms Disease progression management strategies Immune response
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Heat transfer enhanced inorganic phase change material compositing carbon nanotubes for battery thermal management and thermal runaway propagation mitigation 被引量:1
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作者 Xinyi Dai Ping Ping +4 位作者 Depeng Kong Xinzeng Gao Yue Zhang Gongquan Wang Rongqi Peng 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第2期226-238,I0006,共14页
Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery systems.Inorganic phase chan... Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery systems.Inorganic phase change material(PCM)with nonflammability has the potential to achieve this dual function.This study proposed an encapsulated inorganic phase change material(EPCM)with a heat transfer enhancement for battery systems,where Na_(2)HPO_(4)·12H_(2)O was used as the core PCM encapsulated by silica and the additive of carbon nanotube(CNT)was applied to enhance the thermal conductivity.The microstructure and thermal properties of the EPCM/CNT were analyzed by a series of characterization tests.Two different incorporating methods of CNT were compared and the proper CNT adding amount was also studied.After preparation,the battery thermal management performance and TR propagation mitigation effects of EPCM/CNT were further investigated on the battery modules.The experimental results of thermal management tests showed that EPCM/CNT not only slowed down the temperature rising of the module but also improved the temperature uniformity during normal operation.The peak battery temperature decreased from 76℃to 61.2℃at 2 C discharge rate and the temperature difference was controlled below 3℃.Moreover,the results of TR propagation tests demonstrated that nonflammable EPCM/CNT with good heat absorption could work as a TR barrier,which exhibited effective mitigation on TR and TR propagation.The trigger time of three cells was successfully delayed by 129,474 and 551 s,respectively and the propagation intervals were greatly extended as well. 展开更多
关键词 Inorganic phase change material Carbon nanotube Battery thermal management Thermal runaway propagation Fire resistance ENCAPSULATION
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Whole-process case management effects on mental state and selfcare ability in patients with liver cancer 被引量:1
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作者 Man-Di Ju Qin Qin Meng Li 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第3期833-841,共9页
BACKGROUND Regarding the incidence of malignant tumors in China,the incidence of liver cancer ranks fourth,second only to lung,gastric,and esophageal cancers.The case fatality rate ranks third after lung and cervical ... BACKGROUND Regarding the incidence of malignant tumors in China,the incidence of liver cancer ranks fourth,second only to lung,gastric,and esophageal cancers.The case fatality rate ranks third after lung and cervical cancer.In a previous study,the whole-process management model was applied to patients with breast cancer,which effectively reduced their negative emotions and improved treatment adherence and nursing satisfaction.METHODS In this single-center,randomized,controlled study,60 randomly selected patients with liver cancer who had been admitted to our hospital from January 2021 to January 2022 were randomly divided into an observation group(n=30),who received whole-process case management on the basis of routine nursing mea-sures,and a control group(n=30),who were given routine nursing measures.We compared differences between the two groups in terms of anxiety,depression,the level of hope,self-care ability,symptom distress,sleep quality,and quality of life.RESULTS Post-intervention,Hamilton anxiety scale,Hamilton depression scale,memory symptom assessment scale,and Pittsburgh sleep quality index scores in both groups were lower than those pre-intervention,and the observation group had lower scores than the control group(P<0.05).Herth hope index,self-care ability assessment scale-revision in Chinese,and quality of life measurement scale for patients with liver cancer scores in both groups were higher than those pre-intervention,with higher scores in the observation group compared with the control group(P<0.05).CONCLUSION Whole-process case management can effectively reduce anxiety and depression in patients with liver cancer,alleviate symptoms and problems,and improve the level of hope,self-care ability,sleep quality,and quality of life,as well as provide feasible nursing alternatives for patients with liver cancer. 展开更多
关键词 Liver cancer Mental state Self-care ability Whole-process case management Life quality NURSING
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Systematic review of risk factors,prognosis,and management of colorectal signet-ring cell carcinoma 被引量:1
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作者 Frederiek Nuytens Vincent Drubay +2 位作者 Clarisse Eveno Florence Renaud Guillaume Piessen 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第5期2141-2158,共18页
BACKGROUND Colorectal signet-ring cell carcinoma(CSRCC)is a rare clinical entity which accounts for approximately 1%of all colorectal cancers.Although multiple studies concerning this specific topic have been publishe... BACKGROUND Colorectal signet-ring cell carcinoma(CSRCC)is a rare clinical entity which accounts for approximately 1%of all colorectal cancers.Although multiple studies concerning this specific topic have been published in the past decades,the pathogenesis,associated risk factors,and potential implications on treatment are still poorly understood.Besides the low incidence,historically confusing histological criteria have resulted in confusing data.Nevertheless,the rising incidence of CSRCC along with relatively young age at presentation and associated dismal prognosis,highlight the actual interest to synthesize the known literature regarding CSRCC.AIM To provide an updated overview of risk factors,prognosis,and management of CSRCC.METHODS A literature search in the MEDLINE/PubMed database was conducted with the following search terms used:‘Signet ring cell carcinoma’and‘colorectal’.Studies in English language,published after January 1980,were included.Studies included in the qualitative synthesis were evaluated for content concerning epidemiology,risk factors,and clinical,diagnostic,histological,and molecular features,as well as metastatic pattern and therapeutic management.If possible,presented data was extracted in order to present a more detailed overview of the literature.RESULTS In total,67 articles were included for qualitative analysis,of which 54 were eligible for detailed data extraction.CSRCC has a reported incidence between 0.1%-2.4%and frequently presents with advanced disease stage at the time of diagnosis.CSRCC is associated with an impaired overall survival(5-year OS:0%-46%)and a worse stagecorrected outcome compared to mucinous and not otherwise specified adenocarcinoma.The systematic use of exploratory laparoscopy to determine the presence of peritoneal metastases has been advised.Surgery is the mainstay of treatment,although the rates of curative resection in CSRCC(21%-82%)are lower compared to those in other histological types.In case of peritoneal metastasis,cytoreductive surgery with hyperthermic intraperitoneal chemotherapy should only be proposed in selected patients.CONCLUSION CSRCC is a rare clinical entity most often characterized by young age and advanced disease at presentation.As such,diagnostic modalities and therapeutic approach should be tailored accordingly. 展开更多
关键词 Colorectal cancer Signet-ring cell histology Poorly cohesive cells Systematic review Risk factors PROGNOSIS Therapeutic management
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A Blockchain-Based Life-Cycle Environmental Management Framework for Hospitals in the COVID-19 Context 被引量:1
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作者 Botao Zhong Han Gao +1 位作者 Lieyun Ding Yuhang Wang 《Engineering》 SCIE EI CAS CSCD 2023年第1期208-221,共14页
During the coronavirus disease 2019 (COVID-19) emergency, many hospitals were built or renovated around the world to meet the challenges posed by the rising number of infected cases. Environmental management in the ho... During the coronavirus disease 2019 (COVID-19) emergency, many hospitals were built or renovated around the world to meet the challenges posed by the rising number of infected cases. Environmental management in the hospital life cycle is vital in preventing nosocomial infection and includes many infection control procedures. In certain urgent situations, a hospital must be completed quickly, and work process approval and supervision must therefore be accelerated. Thus, many works cannot be checked in detail. This results in a lack of work liability control and increases the difficulty of ensuring the fulfillment of key infection prevention measures. This study investigates how blockchain technology can transform the work quality inspection workflow to assist in nosocomial infection control under a fast delivery requirement. A blockchain-based life-cycle environmental management framework is proposed to track the fulfillment of crucial infection control measures in the design, construction, and operation stages of hospitals. The proposed framework allows for work quality checking after the work is completed, when some work cannot be checked on time. Illustrative use cases are selected to demonstrate the capabilities of the developed solution. This study provides new insights into applying blockchain technology to address the challenge of environmental management brought by rapid delivery requirements. 展开更多
关键词 Blockchain Envir onmental management Nosocomial infection control work quality management Life-cycle traceability
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