Winter wheat yield improvement by genetic gain across different provinces in China

The replacement of winter wheat varieties has contributed significantly to yield improvement worldwide,with remarkable progress in China.Drawing on two sets of data,production yield from the National Bureau of Statistics of China and experimental yield from literature,this study aims to(1)illustrate the increasing patterns of production yield among different provinces from 1978 to 2018 in China,(2)explore the genetic gain in yield and yield relevant traits through the variety replacement based on experimental yield from 1937 to 2016 in China,and(3)compare the yield gap between experimental yield and production yield.The results show that both the production and experimental yields significantly increased along with the variety replacement.The national annual yield increase ratio for the production yield was 1.67%from 1978 to 2018,varying from 0.96%in Sichuan Province to 2.78%in Hebei Province;such ratio for the experimental yield was 1.13%from 1937 to 2016.The yield gap between experimental and production yields decreased from the 1970s to the 2010s.This study reveals significant increases in some yield components consequent to variety replacement,including thousand-grain weight,kernel number per spike,and grain number per square meter;however,no change is shown in spike number per square meter.The biomass and harvest index consistently and significantly increased,whereas the plant height decreased significantly.

利多卡因通过抑制NETs改善阿霉素引起的心脏毒性

目的通过动物实验验证利多卡因抑制中性粒细胞胞外诱捕网(NETs)减轻阿霉素引起的心脏毒性。方法将30只C57BL/6小鼠随机分为对照组、阿霉素组(DOX组)和利多卡因+阿霉素组(LIDO+DOX组),每组10只。对照组单次腹腔注射生理盐水1 mL/100 g;DOX组单次腹腔注射阿霉素15 mg/kg;LIDO+DOX组尾静脉注射利多卡因6 mg/kg,30 min后腹腔注射阿霉素15 mg/kg。于第10天,取小鼠血清检测各组小鼠磷酸肌酸激酶(CK)、磷酸肌酸激酶同工酶(CK-MB)水平;采用酶联免疫吸附试验(ELISA)检测各组小鼠血浆NETs标志物游离DNA(cf-DNA)、瓜氨酸组蛋白3(CitH3)、髓过氧化物酶-DNA(MPO-DNA)的水平;采用免疫荧光法检测各组小鼠心脏组织NETs相关标记物中CitH3、髓过氧化物酶(MPO)的表达量。结果DOX组小鼠血清CK、CK-MB水平明显高于对照组和LIDO+DOX组小鼠(P<0.05)。ELISA检测结果显示,DOX组与LIDO+DOX组小鼠血浆MPO-DNA、CitH3和cf-DNA水平明显高于对照组(P<0.05),但LIDO+DOX组小鼠血浆MPO-DNA、CitH3和cf-DNA水平明显低于DOX组(P<0.05)。免疫荧光法检测结果发现,DOX组小鼠心肌组织中MPO和CitH3表达量明显高于对照组和LIDO+DOX组(P<0.05)。结论利多卡因可能是通过抑制NETs的表达来缓解阿霉素引起的心脏毒性。

Preweaning period is a critical window for rumen microbial regulation of average daily gain in Holstein heifer calves

Background Rumen bacterial groups can affect growth performance,such as average daily gain(ADG),feed intake,and efficiency.The study aimed to investigate the inter-relationship of rumen bacterial composition,rumen fermentation indicators,serum indicators,and growth performance of Holstein heifer calves with different ADG.Twelve calves were chosen from a trail with 60 calves and divided into higher ADG(HADG,high pre-and post-weaning ADG,n=6)and lower ADG(LADG,low pre-and post-weaning ADG,n=6)groups to investigate differences in bacterial composition and functions and host phenotype.Results During the preweaning period,the relative abundances of propionate producers,including g_norank_f_Butyricicoccaceae,g_Pyramidobacter,and g_norank_f_norank_o_Clostridia_vadin BB60_group,were higher in HADG calves(LDA>2,P<0.05).Enrichment of these bacteria resulted in increased levels of propionate,a gluconeogenic precursor,in preweaning HADG calves(adjusted P<0.05),which consequently raised serum glucose concentrations(adjusted P<0.05).In contrast,the relative abundances of rumen bacteria in post-weaning HADG calves did not exert this effect.Moreover,no significant differences were observed in rumen fermentation parameters and serum indices between the two groups.Conclusions The findings of this study revealed that the preweaning period is the window of opportunity for rumen bacteria to regulate the ADG of calves.

Topological laser on square lattice with gain–loss-induced higher-order corner modes

We investigate the higher-order topological laser in the two-dimensional(2D) coupled-cavity array. By adding staggered on-site gain and loss to the 2D Hermitian array with a trivial phase, the system will emerge degenerate topological corner modes, which are protected by bulk band gap. For such a non-Hermitian model, by adjusting the parameters of the system and introducing the pumping into the cavity at the corner, a single-mode lasing with topological protection emerges.Furthermore, single-mode lasing exists over a wide range of pumping strengths. No matter where the cavity is initially stimulated, after enough time evolution, all the cavities belonging to the topological corner mode can emit a stable laser.

A Stroke-Limitation AMD Control System with Variable Gain and Limited Area for High-Rise Buildings

Collisions between a moving mass and an anti-collision device increase structural responses and threaten structural safety.An active mass damper(AMD)with stroke limitations is often used to avoid collisions.However,a strokelimited AMD control system with a fixed limited area shortens the available AMD stroke and leads to significant control power.To solve this problem,the design approach with variable gain and limited area(VGLA)is proposed in this study.First,the boundary of variable-limited areas is calculated based on the real-time status of the moving mass.The variable gain(VG)expression at the variable limited area is deduced by considering the saturation of AMD stroke.Then,numerical simulations of a stroke-limited AMD control system with VGLA are conducted on a high-rise building structure.These numerical simulations show that the proposed approach has superior strokelimitation performance compared with a stroke-limited AMD control system with a fixed limited area.Finally,the proposed approach is validated through experiments on a four-story steel frame.

基于GAIN-LSTM网络的雷达PRI序列还原及识别方法

开展脉冲重复间隔(Pulse Repetition Interval,PRI)模式识别工作是电子支援系统的一项重要任务。现代复杂电磁环境下,受雷达辐射源部署和接收设备本身影响,雷达脉冲丢失率极高,导致分选后PRI序列调制规律被破坏,现有的PRI模式识别方法准确率不足。针对上述问题,从PRI序列还原角度出发,并结合PRI序列本质是时序序列的特点,提出GAIN-LSTM(Generative Adversarial Imputation Nets and Long Short Term Memory)网络架构,其先对丢失脉冲位置进行补全操作,恢复PRI调制规律,然后对还原后PRI序列进行调制模式识别。仿真结果表明,提出的GAIN-LSTM网络架构在脉冲丢失率70%时仍保持95%的正确识别率。

ANovel Non-Isolated Cubic DC-DC Converter with High Voltage Gain for Renewable Energy Power Generation System

In recent years,switched inductor(SL)technology,switched capacitor(SC)technology,and switched inductor-capacitor(SL-SC)technology have been widely applied to optimize and improve DC-DC boost converters,which can effectively enhance voltage gain and reduce device stress.To address the issue of low output voltage in current renewable energy power generation systems,this study proposes a novel non-isolated cubic high-gain DC-DC converter based on the traditional quadratic DC-DC boost converter by incorporating a SC and a SL-SC unit.Firstly,the proposed converter’s details are elaborated,including its topology structure,operating mode,voltage gain,device stress,and power loss.Subsequently,a comparative analysis is conducted on the voltage gain and device stress between the proposed converter and other high-gain converters.Then,a closed-loop simulation system is constructed to obtain simulation waveforms of various devices and explore the dynamic performance.Finally,an experimental prototype is built,experimental waveforms are obtained,and the experimental dynamic performance and conversion efficiency are analyzed.The theoretical analysis’s correctness is verified through simulation and experimental results.The proposed converter has advantages such as high voltage gain,low device stress,high conversion efficiency,simple control,and wide input voltage range,achieving a good balance between voltage gain,device stress,and power loss.The proposed converter is well-suited for renewable energy systems and holds theoretical significance and practical value in renewable energy applications.It provides an effective solution to the issue of low output voltage in renewable energy power generation systems.

Design of a Low Power Low-Noise Amplifier with Improved Gain/Noise Ratio

This work details the development of a broad-spectrum LNA (Low Noise Amplifier) circuit using a 65 nm CMOS technology. The design incorporates an inductive degeneracy circuit, employing a theoretical approach to enhance gain, minimize noise levels, and uphold low power consumption. The progression includes a shift to a cascode structure to further refine LNA parameters. Ultimately, with a 1.8 V bias, the achieved performance showcases a gain-to-noise figure ratio of 16 dB/0.5 dB, an IIP3 linearity at 5.1 dBm, and a power consumption of 3 mW. This architecture is adept at operating across a wide frequency band spanning from 0.5 GHz to 6 GHz, rendering it applicable in diverse RF scenarios.

Analysis of the Effects of Maternal Body Mass Index and Gestational Weight Gain on Maternal and Neonatal Outcomes in Twin Pregnancy

Objective:To investigate the effects of maternal body mass index(BMI)and gestational weight gain on maternal and neonatal outcomes in twin pregnancies.Methods:Five hundred cases of twin pregnancies were divided into a low body weight group(68 cases),a normal weight group(355 cases),an overweight group(65 cases),and an obesity group(12 cases)according to the World Health Organization(WHO)Body Mass Index(BMI)classification guidelines Results:Comparison of weight gain during different pregnancies revealed that pregnant women were mainly of low weight and average weight.The higher the BMI before pregnancy,the higher the incidence of excessive weight gain during pregnancy.The incidences of gestational diabetes mellitus(GDM)and premature rupture of membranes in women with low weight gain were significantly higher than those in women with average weight gain and high weight gain(P<0.05).The incidences of gestational hypertension,preeclampsia,and anemia in women with high weight gain were significantly higher than those in women with low weight gain and average weight gain(P<0.05).The incidence of neonatal birth weight,fetal distress,and macrosomia in the high weight gain group was significantly higher than those in the low weight gain and average weight gain groups(P<0.05).The birth weight of newborns in low-weight gain mothers was significantly lower than that of normal-weight gain mothers(P<0.05).Conclusion:Poor maternal and infant outcomes were common in women with insufficient or excessive weight gain during pregnancy.Therefore,for women with twin pregnancies,weight management is crucial to ensure maternal and infant health.

Genetic gain and inbreeding from simulation of different genomic mating schemes for pig improvement

Background Genomic selection involves choosing as parents those elite individuals with the higher genomic estimated breeding values(GEBV)to accelerate the speed of genetic improvement in domestic animals.But after multi-generation selection,the rate of inbreeding and the occurrence of homozygous harmful alleles might increase,which would reduce performance and genetic diversity.To mitigate the above problems,we can utilize genomic mating(GM)based upon optimal mate allocation to construct the best genotypic combinations in the next generation.In this study,we used stochastic simulation to investigate the impact of various factors on the efficiencies of GM to optimize pairing combinations after genomic selection of candidates in a pig population.These factors included:the algorithm used to derive inbreeding coefficients;the trait heritability(0.1,0.3 or 0.5);the kind of GM scheme(focused average GEBV or inbreeding);the approach for computing the genomic relationship matrix(by SNP or runs of homozygosity(ROH)).The outcomes were compared to three traditional mating schemes(random,positive assortative or negative assortative matings).In addition,the performance of the GM approach was tested on real datasets obtained from a Large White pig breeding population.Results Genomic mating outperforms other approaches in limiting the inbreeding accumulation for the same expected genetic gain.The use of ROH-based genealogical relatedness in GM achieved faster genetic gains than using relatedness based on individual SNPs.The GROH-based GM schemes with the maximum genetic gain resulted in 0.9%-2.6%higher rates of genetic gainΔG,and 13%-83.3%lowerΔF than positive assortative mating regardless of heritability.The rates of inbreeding were always the fastest with positive assortative mating.Results from a purebred Large White pig population,confirmed that GM with ROH-based GRM was more efficient than traditional mating schemes.Conclusion Compared with traditional mating schemes,genomic mating can not only achieve sustainable genetic progress but also effectively control the rates of inbreeding accumulation in the population.Our findings demonstrated that breeders should consider using genomic mating for genetic improvement of pigs.

key-nets同态加密方案的安全性分析及改进

key-nets作为第一个光学同态加密方案,用以保护用于机器学习的图像的隐私。但是在视觉传感器被非法获得的情况下,笔者通过求解线性方程组得到了key-nets方案中用于加密图像的密钥。鉴于该方案中存在的这一安全隐患以及机器学习模型训练的困难性,笔者借助Diffie-Hellman密钥交换协议,提出了一种在不改变原卷积网络结构的条件下,每次加密都可以使用不同的广义随机矩阵的同态加密方案,进而在提高了key-nets的加密密钥的安全性的同时,也提高了与视觉传感器相匹配的卷积网络的安全性。通过对方案的可行性、隐私参数以及前向安全性、后向安全性等方面的分析,证明了改进后的方案即使在攻击者非法获得视觉传感器的情况下,图片信息仍能够被保护。

Intoxication Induced by Urea Containing Diets in Broiler Chickens: Effect on Weight Gain, Feed Conversion Ratio, Hematological and Biochemical Profiles

Urea as a source of cheap non-protein nitrogen is used to adulterate fish and meat meals which are basic components of broiler diets. The present study was carried out to elucidate the effects of urea on weight gain, and hematological and biochemical profiles. A total of 48 broiler chicks were randomly allotted into 4 groups, designated Groups 1, 2, 3 and 4 of 12 birds each. Birds in Groups 2, 3 and 4 were fed on diets containing urea at the levels of 1%, 2.5% and 4%, respectively. Birds in Group 1 served as control and were not exposed to urea. Experimentation period was for 3 weeks and experiment was terminated when birds were 42 days of age. Body weight of all intoxicated birds at the various intervals was significantly decreased in comparison with that of the untreated control. Compared with control, all intoxicated broilers manifested significant (P ≤ 0.05) decrease in all hematological parameters involving erythrocytic and total leucocytic counts, Hemoglobin (Hb) and Packed Cell Volume (PCV) on a dose- and time-pattern. In comparison with the control levels, biochemical profile of the intoxicated birds disclosed significant decrease in blood glucose level and significant increase in serum uric acid, urea, Alkaline Phosphatase (ALP) and Lactate Dehydrogenase (LDH) levels. Based upon the present data, it was concluded that the addition of urea to broiler diets bears serious sequences concerning the general health condition, performance, weight gain, and hematological and biochemical profiles.

Situational Analysis of Malaria Control Following the 2021 Distribution of Long Lasting Insecticide-Treated Bed Nets in the Tiko Health District, South West Region, Cameroon

Malaria is still a major public health concern in Cameroon as more than 20 million people are at risk of the disease. Despite the government’s effort to scale up the distribution of long lasting insecticide-treated bed nets (LLINs), full ownership and optimal use is still limited. In 2021, over a million LLINs were made available for distribution in the South West Region. However, the current situation of malaria has not yet been ascertained following the 2021 mass distribution campaign (MDC). Therefore, the aim of this study was to determine LLIN ownership, coverage, usage and the prevalence of malaria following the 2021 MDC in the Tiko Health District (THD), South West Region of Cameroon. A cross-sectional study was carried from May 1 to 27, 2022 in which a multi-stage sampling technique was used to enroll eligible participants. Data were collected from household heads using questionnaires and capillary blood samples collected from consented household members were used to test for malaria. Data were analyzed using SPSS version 25 at 0.05 significance level. From the 150 households surveyed, 96 (64.0%) owned a mosquito net before the recent MDC. There was an overall significant increase (p p = 0.644) in LLINs ownership between areas where door-to-door (79.5%) and fixed “Hit and Run” (75.8%) strategies were used in the distribution of LLINs in THD. The prevalence of malaria was 10.2%. The regular use of LLINs was significantly associated (p = 0.007) with low malaria prevalence. The 2021 MDC had an impact on malaria prevalence in those who properly used them.

Scale and Associated Factors of Using Pyrethroid-Impregnated Mosquito Nets as Fishing Tools on Nokoué Lake within Sô-Ava Municipality in Benin, 2020

Background: In lacustrine communities, whether in Benin or elsewhere, populations use impregnated mosquito nets (IMNs) as fishing nets. This depletes the lake of its fishery resources, which in turn are contaminated by the pyrethroids impregnated in the nets. This study aims to determine the scale and factors associated with the use of pyrethroid-impregnated mosquito nets as fishing tools in the municipality of Sô-Ava in Benin. Methods: This is a cross-sectional and analytical study with two components. First, a quantitative component was made up of 280 volunteers who were interviewed in the seven districts of the city. Data collection was done in two phases: the first from September to October 2020, and the second in August 2022. Data were analyzed with Stata and logistic regression was used. Another qualitative component was made up of forty participants chosen by reasoned choice, of which 32 were split into four focus groups of eight members each, and the rest participated in semi-structured interviews. Triangulation of the different sources was used to analyze the data. Results: Around 67% of the population reported using impregnated mosquito nets as fishing tools and 33% exclusively for malaria. Seasonal fishermen (ORa = 2.03, CI = 1.35 - 4.97, P = 0.004) and years of professional experience (ORa = 1.53, CI = 1.00 - 2.05, P = 0.021) increase the risk of using these nets as fishing tools. The use of insecticide-treated mosquito nets against mosquitoes causes skin scratching and impairs breathing because of the impregnation products, as reported by respondents. Conclusion: A high prevalence of inappropriate use of impregnated mosquito nets in fishing practices is highlighted in this study. Interviews in the field revealed that nets are diverted for fishing purposes to increase the volume of catches. Consequently, it will be appropriate to assess the pyrethroid content in water and fishery products.

Boundedness and liveness enforcement for labeled Petri nets using transition priority

This paper deals with the supervisory control problem of discrete event systems modeled by labeled Petri nets. The system is originally unbounded. First, the solvability of the problem is confirmed. A necessary condition is given and proven for the existence of a feasible priority-based controller based on the notions of liveness and transition invariants. Next, a cyclic behavior graph is constructed, which shows the reachable markings that guarantee the maximum liveness of the system within a given bound vector. Finally, an on-line control strategy is proposed to enforce boundedness and liveness to the given system by appending priority relations to transitions. The dynamic priority relation changes flexibly according to the current state of the system and enforces the system evolving in a bounded and live manner. In addition, numerical examples are studied to verify the validity of the proposed approach that remains the structure of the plant net and is efficient for on-line control.

Fixed-Time Stabilization of a Class of Strict-Feedback Nonlinear Systems via Dynamic Gain Feedback Control

This paper presents a novel fixed-time stabilization control(FSC)method for a class of strict-feedback nonlinear systems involving unmodelled system dynamics.The key feature of the proposed method is the design of two dynamic parameters.Specifically,a set of auxiliary variables is first introduced through state transformation.These variables combine the original system states and the two introduced dynamic parameters,facilitating the closed-loop system stability analyses.Then,the two dynamic parameters are delicately designed by utilizing the Lyapunov method,ensuring that all the closed-loop system states are globally fixed-time stable.Compared with existing results,the“explosion of complexity”problem of backstepping control is avoided.Moreover,the two designed dynamic parameters are dependent on system states rather than a time-varying function,thus the proposed controller is still valid beyond the given fixedtime convergence instant.The effectiveness of the proposed method is demonstrated through two practical systems.

Planar InAlAs/InGaAs avalanche photodiode with 360 GHz gain×bandwidth product

This paper describes a guardring-free planar InAlAs/InGaAs avalanche photodiode(APD)by computational simulations and experimental results.The APD adopts the structure of separate absorption,charge,and multiplication(SACM)with top-illuminated.Computational simulations demonstrate how edge breakdown effect is suppressed in the guardringfree structure.The fabricated APD experiment results show that it can obtain a very low dark current while achieving a high gain×bandwidth(GB)product.The dark current is 3 nA at 0.9Vb r,and the unit responsivity is 0.4 A/W.The maximum3 dB bandwidth of 24 GHz and a GB product of 360 GHz are achieved for the fabricated APD operating at 1.55μm.

High gain and circularly polarized substrate integrated waveguide cavity antenna array based on metasurface

Two substrate integrated waveguide(SIW) cavity antenna arrays based on metasurface are proposed in this paper. By rotating the metasurface element, circularly polarized and high gain antennas are achieved respectively. Firstly, multi-mode resonance theory is employed to broaden the bandwidth of the slot antenna. And then, an SIW cavity composed of 4×4 cornercut elements is added on the top of the slot antenna to achieve the circular polarization and improve the front-to-back ratio. Thirdly, the metasurface elements are sequentially rotated and a high gain antenna with 2-dBi enhancement on average in the operation band is obtained. Based on the two antenna units, two 2×2 antenna arrays are designed. The circularly polarized and high gain antenna arrays are both fabricated to verify the correctness. Furthermore, the novel wideband phase shifter is employed in the circularly polarized antenna to obtain an operating bandwidth of 38%(4.05 GHz–5.95 GHz)and AR bandwidth of 24.9%(4.4 GHz–5.65 GHz). The bandwidth of the high gain antenna can reach 42.7%(3.95 GHz–6.1 GHz) and with the gain enhancement of 2 dBi compared with that of the circularly polarized antenna. The gain remains steady in most of operating band within a variation of 1 dBi. It is remarkable that the rotating of the metasurface element has a great influence on the antenna performance, which provides a new explication for the multi-function antenna design.

Design of a High-Gain 2 × 1 Array Antenna for S-Band Applications

Antennas are an indispensable element in wireless networks. For long-distance wireless communication, antenna gains need to be very strong (highly directive) because the signal from the antenna loses a lot of strength as it travels over long distances. This is true in the military with missile, radar, and satellite systems, etc. Antenna arrays are commonly employed to focus electromagnetic waves in a certain direction that cannot be achieved perfectly with a single-element antenna. The goal of this study is to design a rectangular microstrip high-gain 2 × 1 array antenna using ADS Momentum. This microstrip patch array design makes use of the RT-DUROID 5880 as a substrate with a dielectric constant of 2.2, substrate height of 1.588 mm, and tangent loss of 0.001. To achieve efficient gain and return loss characteristics for the proposed array antenna, RT-Duroid is a good choice of dielectric material. The designed array antenna is made up of two rectangular patches, which have a resonance frequency of 3.3 GHz. These rectangular patches are excited by microstrip feed lines with 13 mm lengths and 4.8 mm widths. The impedance of the patches is perfectly matched by these transmission lines, which helps to get better antenna characteristics. At a resonance frequency of 3.3 GHz, the suggested antenna array has a directivity of 10.50 dB and a maximum gain of 9.90 dB in the S-band. The S parameters, 3D radiation pattern, directivity, gain, and efficiency of the constructed array antenna are all available in ADS Momentum.

Free form deformation and symmetry constraint‐based multimodal brain image registration using generative adversarial nets

Multi‐modal brain image registration has been widely applied to functional localisation,neurosurgery and computational anatomy.The existing registration methods based on the dense deformation fields involve too many parameters,which is not conducive to the exploration of correct spatial correspondence between the float and reference images.Meanwhile,the unidirectional registration may involve the deformation folding,which will result in the change of topology during registration.To address these issues,this work has presented an unsupervised image registration method using the free form deformation(FFD)and the symmetry constraint‐based generative adversarial networks(FSGAN).The FSGAN utilises the principle component analysis network‐based structural representations of the reference and float images as the inputs and uses the generator to learn the FFD model parameters,thereby producing two deformation fields.Meanwhile,the FSGAN uses two discriminators to decide whether the bilateral registration have been realised simultaneously.Besides,the symmetry constraint is utilised to construct the loss function,thereby avoiding the deformation folding.Experiments on BrainWeb,high grade gliomas,IXI and LPBA40 show that compared with state‐of‐the‐art methods,the FSGAN provides superior performance in terms of visual comparisons and such quantitative indexes as dice value,target registration error and computational efficiency.