With the rapid development of low-orbit satellite com-munication networks both domestically and internationally,space-terrestrial integrated networks will become the future development trend.For space and terrestrial ...With the rapid development of low-orbit satellite com-munication networks both domestically and internationally,space-terrestrial integrated networks will become the future development trend.For space and terrestrial networks with limi-ted resources,the utilization efficiency of the entire space-terres-trial integrated networks resources can be affected by the core network indirectly.In order to improve the response efficiency of core networks expansion construction,early warning of the core network elements capacity is necessary.Based on the inte-grated architecture of space and terrestrial network,multidimen-sional factors are considered in this paper,including the number of terminals,login users,and the rules of users’migration during holidays.Using artifical intelligence(AI)technologies,the regis-tered users of the access and mobility management function(AMF),authorization users of the unified data management(UDM),protocol data unit(PDU)sessions of session manage-ment function(SMF)are predicted in combination with the num-ber of login users,the number of terminals.Therefore,the core network elements capacity can be predicted in advance.The proposed method is proven to be effective based on the data from real network.展开更多
Recent developments in the aerospace industry have led to a dramatic reduction in the manufacturing and launch costs of low Earth orbit satellites.The new trend enables the paradigm shift of satelliteterrestrial integ...Recent developments in the aerospace industry have led to a dramatic reduction in the manufacturing and launch costs of low Earth orbit satellites.The new trend enables the paradigm shift of satelliteterrestrial integrated networks with global coverage.In particular,the integration of 5G communication systems and satellites has the potential to restructure nextgeneration mobile networks.By leveraging the network function virtualization and network slicing,the satellite 5G core networks will facilitate the coordination and management of network functions in satellite-terrestrial integrated networks.We are the first to deploy a 5G core network on a real-world satellite to investigate its feasibility.We conducted experiments to validate the satellite 5G core network functions.The validated procedures include registration and session setup procedures.The results show that the satellite 5G core network can function normally and generate correct signaling.展开更多
The Internet of Things(IoTs)has become an essential component of the 5th Generation(5G)network and beyond,accelerating the transition to digital society.The increasing signaling traffic generated by billions of IoT de...The Internet of Things(IoTs)has become an essential component of the 5th Generation(5G)network and beyond,accelerating the transition to digital society.The increasing signaling traffic generated by billions of IoT devices has placed significant strain on the 5G Core network(5GC)control plane.To address this issue,the 3rd Gener-ation Partnership Project(3GPP)first proposed a Service-Based Architecture(SBA),intending to create a flexible,scalable,and agile cloud-native 5GC.However,considering the coupling of protocol states and functions,there are still many challenges to fully utilize the benefits of the cloud computing and orchestrate the 5GC in a cloud-native manner.We propose a Message-Level StateLess Design(ML-SLD)to provide a cloud-native 5GC from an architectural standpoint in this paper.Firstly,we propose an innovative mechanism for servitization of the N2 interface to maintain the connection between Radio Access Network(RAN)and the 5GC,avoiding interruptions and dropouts of large-scale user data.Furthermore,we propose an On-demand Message Forwarding(OMF)al-gorithm to reduce the impact of cloud fluctuations on the performance of cloud-native 5GC.Finally,we create a prototype that is based on the OpenAirInterface(OAI)5G core network projects,with all Network Functions(NFs)packaged in dockers and deployed in a kubernetes-based cloud environment.Several experiments have been built with UERANSIM and Chaosblade simulation tools.The findings demonstrate the viability and efficiency of our proposed methods.展开更多
This paper studies and analyzes the rigorous requirements of railway 5G private network core network(5GC)equipment based on network function virtualization(NFV)technology in terms of reliability,security,latency and o...This paper studies and analyzes the rigorous requirements of railway 5G private network core network(5GC)equipment based on network function virtualization(NFV)technology in terms of reliability,security,latency and other aspects of communication cloud,compares cloud platform schemes with different decoupling modes,and proposes that railway 5GC should be implemented by software and hardware integration scheme or software and hardware two-layer decoupling scheme.At the same time,the redundancy and disaster recovery schemes and measures that can be taken by 5GC based on cloud platform are proposed.Finally,taking the products of ZTE Corporation as an example,the implementation architecture of railway 5GC cloud platform in 1+1 redundancy mode is given.It serves as a reference for the engineering construction of 5G-R core network.展开更多
Secure authentication between user equipment and 5G core network is a critical issue for 5G system.However,the traditional authentication protocol 5 G-AKA and the centralized key database are at risk of several securi...Secure authentication between user equipment and 5G core network is a critical issue for 5G system.However,the traditional authentication protocol 5 G-AKA and the centralized key database are at risk of several security problems,e.g.key leakage,impersonation attack,MitM attack and single point of failure.In this paper,a blockchain based asymmetric authentication and key agreement protocol(BC-AKA)is proposed for distributed 5G core network.In particular,the key used in the authentication process is replaced from a symmetric key to an asymmetric key,and the database used to store keys in conventional 5G core network is replaced with a blockchain network.A proof of concept system for distributed 5G core network is built based on Ethereum and ECC-Secp256 k1,and the efficiency and effectiveness of the proposed scheme are verified by the experiment results.展开更多
The emergency relating to software-defined networking (SDN), especially in terms of the prototype associated with OpenFlow, provides new possibilities for innovating on network design. Researchers have started to ex...The emergency relating to software-defined networking (SDN), especially in terms of the prototype associated with OpenFlow, provides new possibilities for innovating on network design. Researchers have started to extend SDN to cellular networks. Such new programmable architecture is beneficial to the evolution of mobile networks and allows operators to provide better services. The typical cellular network comprises radio access network (RAN) and core network (CN); hence, the technique roadmap diverges in two ways. In this paper, we investigate SoftRAN, the latest SDN solution for RAN, and SoftCell and MobileFlow, the latest solutions for CN. We also define a series of control functions for CROWD. Unlike in the other literature, we emphasize only softwaredefined cellular network solutions and specifications in order to provide possible research directions.展开更多
The developing mobile technologies have resulted in operators focusing on how to optimize their 2G networks and ensure a smooth network end, there are two approaches for upgrade: one core network with a 2G-radio netwo...The developing mobile technologies have resulted in operators focusing on how to optimize their 2G networks and ensure a smooth network end, there are two approaches for upgrade: one core network with a 2G-radio network, while the other is (Mobile Switching Center) with WCDMA MSCS (Mobile Gateway) to optimize the Core network hierararchy展开更多
ZTE Corporation, a leading global provider of telecommunications equipment and network solutions, announced on April 26, 2010 that it has been chosen by China Mobile to deliver its IMS core network in key Chinese prov...ZTE Corporation, a leading global provider of telecommunications equipment and network solutions, announced on April 26, 2010 that it has been chosen by China Mobile to deliver its IMS core network in key Chinese provinces. The China Mobile' s commercial IMS network will boast 1.4 million lines when it is completed in three months. According to the comprehensive evaluation process by China Mobile, ZTE was ranked among the tier one IMS supplier group for the project this time.展开更多
27 August 2012--ZTE Corporation has signed a deal on a packet-switched core network (CN) for KPN Group Belgium (KPNGB). KPNGB will deploy ZTE's packet-switched CN equipment, which supports unified radio access. T...27 August 2012--ZTE Corporation has signed a deal on a packet-switched core network (CN) for KPN Group Belgium (KPNGB). KPNGB will deploy ZTE's packet-switched CN equipment, which supports unified radio access. The contract is the second of its kind between ZTE and KPNfollows from a construction project with KPN Germany (E-Plus) that was completed in September 2010.展开更多
This article presents the network design schemes of CERNET2 including overall architecture, the backbone, core nodes, access solutions and the CNGI peer centers. CERNET2 connects 25 core nodes distributed in 20 cities...This article presents the network design schemes of CERNET2 including overall architecture, the backbone, core nodes, access solutions and the CNGI peer centers. CERNET2 connects 25 core nodes distributed in 20 cities of China at the speed of 2.5-10 Gb/s. CERNET2 has four unique features. First, its backbone adopts native IPv6 protocols, rather than IPv4/IPv6 dual stack. It is the largest pure IPv6 network in the world. Second, it provides an environment for testing and trial operation of China-made IPv6 core routers. It also allows tests of interconnection, interworking and interoperation among multiple vendors. Third, the large IPv6 address space enables the study on network addresses in a real network environment, which ensures the construction of a secured and trusted CNGI. Last, it is a test-bed for NGI applications.展开更多
As the railway sector intensifies its efforts in the technology research,system R&D and technology application of 5G-R,the paper conducts a preliminary study on its application frequency in terms of its frequency ...As the railway sector intensifies its efforts in the technology research,system R&D and technology application of 5G-R,the paper conducts a preliminary study on its application frequency in terms of its frequency propagation,network carrying capacity,its ability to work as industrial pillar,system applicability,and the compatibility of 5G-R with other systems.In line with China's GSM-R application practice and the application needs,the paper focuses on the study of key technologies such as model alignment of base station equipment,and optimization of 5G-R terminal and core network,identifying the priorities for the China's efforts to develop 5G-R and providing references for the research and application of related technologies.展开更多
Objective:Based on data mining software,applying frequent itemsets,association rules,hierarchical clustering,complex networks and other data mining methods to analyze the usage and compatibility of traditional Chinese...Objective:Based on data mining software,applying frequent itemsets,association rules,hierarchical clustering,complex networks and other data mining methods to analyze the usage and compatibility of traditional Chinese medicine(TCM)patent compound for functional dyspepsia.Method:Use the Chinese patent database to search the compound for the treatment of functional dyspepsia,exclude traditional Chinese medicine extracts,single drugs,combined use of Chinese and Western medicines,etc.,screen the patented compound of TCM,establish an Excel data table,and apply data mining software to The data is subjected to frequency statistics,association rules,cluster analysis and complex network analysis.Result:A total of 238 prescriptions for functional dyspepsia were screened.The four qi of the drugs were mainly warm and calm,the five flavors were mainly sweet and spicy,and the spleen and stomach were the main meridians.The top 10 Chinese medicines with higher frequency are Shanzha、Chenpi、Gancao、Maiya、Jineijin、Fuling、Baizhu、Shenqu、Houpo、Banxia;frequent itemsets show that the drugs are mainly compatible with qi and spleen,qi and digestion;association rules The analysis shows that the common drug pairs used in the treatment of functional dyspepsia include Chenpi-Shanzha、Maiya-Shanzha、Jineijin-Shanzha,etc.;cluster analysis found that there are 4 types of drugs for functional dyspepsia,mainly including drugs for regulating qi-flowing for harmonizing stomach,drugs for soothing liver and promoting Qi,drugs for eliminating food and resolving accumulation,drugs for benefiting qi and strengthening spleen;the 22-flavor Chinese medicine in the core drug network,the core compatibility is mainly to eliminate stagnation and spleen.Conclusion:Data mining research provides a reference for the clinical treatment of functional dyspepsia and the development of TCM formulas;Clinical treatment of functional dyspepsia should grasp the basic principles of strengthening vital energy and eliminating pathogenic factors to benefit qi,strengthen the spleen,and eliminate food.It is a basic treatment method,taking into account the methods of regulating qi-flowing for harmonizing stomach,soothing the liver and relieving depression,relieving dampness and dampness,and combining the specific conditions of patients with syndrome differentiation and treatment.展开更多
Objective:Based on the data mining method,explore the medication rules of Chinese patent medicines for the treatment of digestive system tumors.Method:Based on the"Chinese Traditional Medicine Prescription Databa...Objective:Based on the data mining method,explore the medication rules of Chinese patent medicines for the treatment of digestive system tumors.Method:Based on the"Chinese Traditional Medicine Prescription Database"in https://db.yaozh.com/,collect Chinese patent medicines for the treatment of digestive system tumors,establish an Excel table,and use the ancient and modern medical case cloud platform(V2.2.1)to perform frequency statistics,association rules,and drugs on the data Clustering and complex network analysis.Results:A total of 36 Chinese patent medicines for the treatment of digestive system tumors were screened.The medicinal properties were mainly warm and cold,the taste was bitter and sweet,and the meridians were mainly liver and spleen meridians.High frequency Chinese medicine include Astragalus,Scutellaria-barbata,Ginseng,Curcuma,Triangle,Atractylodes,Hedyotis diffusa,etc.Correlation analysis obtained 17 drug combinations,High-frequency drug pairs include Scutellaria-barbata-Astragalus,Ginseng-Astragalus,Curcuma-Astragalus,Scutellaria-barbata-Curcuma,etc.Cluster analysis found 3 types of drugs.The core drug network is composed of 27 drugs,and the core compatibility network consists of 3 groups of drugs.Conclusion:The Chinese patent compound medicine for the treatment of digestive system tumors has the characteristics of combining cold and warming,replenishing and reducing treatment,and treating the liver and spleen at the same time.The medicine is mainly used to replenish qi and invigorate the spleen,promote blood circulation and remove blood stasis,and clear away heat and detoxification.Replenish qi,nourish yin,invigorate blood,and detoxify are mainly compatible with each other,reflecting the pathogenesis characteristics of"deficiency,stasis,and toxin"in digestive system tumors.Data mining can provide references for the prescription and compatibility of Chinese patent medicines.展开更多
The sixth-generation mobile communication(6G)networks will face more complex endogenous security problems,and it is urgent to propose new universal security theories and establish new practice norms to deal with the...The sixth-generation mobile communication(6G)networks will face more complex endogenous security problems,and it is urgent to propose new universal security theories and establish new practice norms to deal with theªunknown unknownºsecurity threats in cyberspace.This paper first expounds the new paradigm of cyberspace endogenous security and introduces the vision of 6G cyberspace security.Then,it analyzes the security problems faced by the 6G core network,wireless access network,and emerging associated technologies in detail,as well as the corresponding security technology development status and the integrated development of endogenous security and traditional security.Furthermore,this paper describes the relevant security theories and technical concepts under the guidance of the new paradigm of endogenous security.展开更多
The explosive increase of smart devices and mobile traffic results intolerable network latency and degraded service to the end-users. in heavy burden on backhaul and core network, As a complement to core network, edge...The explosive increase of smart devices and mobile traffic results intolerable network latency and degraded service to the end-users. in heavy burden on backhaul and core network, As a complement to core network, edge network contributes to relieving network burden and improving user experience. To investigate the problem of optimizing the total consumption in an edge-core network, the system consumption minimization problem is fromulated, considering the energy consumption and delay. Given that the formulated problem is a mixed nonlinear integer programming (MNIP) , a low-complexity workload allocation algorithm is proposed based on interior-point method. The proposed algorithm has an extremely short running time in practice. Finally, simulation results show that edge network can significantly complement core network with much reduced backhaul energy consumption and delay.展开更多
Determining effective traditional Chinese medicine (TCM) treatments for specific disease conditions or particular patient groups is a difficult issue that necessitates investigation because of the complicated person...Determining effective traditional Chinese medicine (TCM) treatments for specific disease conditions or particular patient groups is a difficult issue that necessitates investigation because of the complicated personalized manifestations in real-world patients and the individualized combination therapies prescribed in clinical settings. In this study, a multistage analysis method that integrates propensity case matching, complex network analysis, and herb set enrichment analysis was proposed to identify effective herb prescriptions for particular diseases (e.g., insomnia). First, propensity case matching was applied to match clinical cases. Then, core network extraction and herb set enrichment were combined to detect core effective herb prescriptions. Effectiveness-based mutual information was used to detect strong herb symptom relationships. This method was applied on a TCM clinical data set with 955 patients collected from well-designed observational studies. Results revealed that groups of herb prescriptions with higher effectiveness rates (76.9% vs. 42.8% for matched samples; 94.2% vs. 84.9% for all samples) compared with the original prescriptions were found. Particular patient groups with symptom manifestations were also identified to help investigate the indications of the effective herb prescriptions.展开更多
基金This work was supported by the National Key Research Plan(2021YFB2900602).
文摘With the rapid development of low-orbit satellite com-munication networks both domestically and internationally,space-terrestrial integrated networks will become the future development trend.For space and terrestrial networks with limi-ted resources,the utilization efficiency of the entire space-terres-trial integrated networks resources can be affected by the core network indirectly.In order to improve the response efficiency of core networks expansion construction,early warning of the core network elements capacity is necessary.Based on the inte-grated architecture of space and terrestrial network,multidimen-sional factors are considered in this paper,including the number of terminals,login users,and the rules of users’migration during holidays.Using artifical intelligence(AI)technologies,the regis-tered users of the access and mobility management function(AMF),authorization users of the unified data management(UDM),protocol data unit(PDU)sessions of session manage-ment function(SMF)are predicted in combination with the num-ber of login users,the number of terminals.Therefore,the core network elements capacity can be predicted in advance.The proposed method is proven to be effective based on the data from real network.
基金supported by the National Key R&D Program of China(2020YFB1805500)National Natural Science Foundation of China(61922017,62032003 and 61921003)。
文摘Recent developments in the aerospace industry have led to a dramatic reduction in the manufacturing and launch costs of low Earth orbit satellites.The new trend enables the paradigm shift of satelliteterrestrial integrated networks with global coverage.In particular,the integration of 5G communication systems and satellites has the potential to restructure nextgeneration mobile networks.By leveraging the network function virtualization and network slicing,the satellite 5G core networks will facilitate the coordination and management of network functions in satellite-terrestrial integrated networks.We are the first to deploy a 5G core network on a real-world satellite to investigate its feasibility.We conducted experiments to validate the satellite 5G core network functions.The validated procedures include registration and session setup procedures.The results show that the satellite 5G core network can function normally and generate correct signaling.
基金funded by the National Key Research and Development Program of China under Grant 2019YFB1803301Beijing Natural Science Foundation(L202002).
文摘The Internet of Things(IoTs)has become an essential component of the 5th Generation(5G)network and beyond,accelerating the transition to digital society.The increasing signaling traffic generated by billions of IoT devices has placed significant strain on the 5G Core network(5GC)control plane.To address this issue,the 3rd Gener-ation Partnership Project(3GPP)first proposed a Service-Based Architecture(SBA),intending to create a flexible,scalable,and agile cloud-native 5GC.However,considering the coupling of protocol states and functions,there are still many challenges to fully utilize the benefits of the cloud computing and orchestrate the 5GC in a cloud-native manner.We propose a Message-Level StateLess Design(ML-SLD)to provide a cloud-native 5GC from an architectural standpoint in this paper.Firstly,we propose an innovative mechanism for servitization of the N2 interface to maintain the connection between Radio Access Network(RAN)and the 5GC,avoiding interruptions and dropouts of large-scale user data.Furthermore,we propose an On-demand Message Forwarding(OMF)al-gorithm to reduce the impact of cloud fluctuations on the performance of cloud-native 5GC.Finally,we create a prototype that is based on the OpenAirInterface(OAI)5G core network projects,with all Network Functions(NFs)packaged in dockers and deployed in a kubernetes-based cloud environment.Several experiments have been built with UERANSIM and Chaosblade simulation tools.The findings demonstrate the viability and efficiency of our proposed methods.
文摘This paper studies and analyzes the rigorous requirements of railway 5G private network core network(5GC)equipment based on network function virtualization(NFV)technology in terms of reliability,security,latency and other aspects of communication cloud,compares cloud platform schemes with different decoupling modes,and proposes that railway 5GC should be implemented by software and hardware integration scheme or software and hardware two-layer decoupling scheme.At the same time,the redundancy and disaster recovery schemes and measures that can be taken by 5GC based on cloud platform are proposed.Finally,taking the products of ZTE Corporation as an example,the implementation architecture of railway 5GC cloud platform in 1+1 redundancy mode is given.It serves as a reference for the engineering construction of 5G-R core network.
基金supported by National Key Research and Development Program of China under Grant 2021YFE0205300Tianjin Natural Science Foundation(19JCYBJC15700)。
文摘Secure authentication between user equipment and 5G core network is a critical issue for 5G system.However,the traditional authentication protocol 5 G-AKA and the centralized key database are at risk of several security problems,e.g.key leakage,impersonation attack,MitM attack and single point of failure.In this paper,a blockchain based asymmetric authentication and key agreement protocol(BC-AKA)is proposed for distributed 5G core network.In particular,the key used in the authentication process is replaced from a symmetric key to an asymmetric key,and the database used to store keys in conventional 5G core network is replaced with a blockchain network.A proof of concept system for distributed 5G core network is built based on Ethereum and ECC-Secp256 k1,and the efficiency and effectiveness of the proposed scheme are verified by the experiment results.
文摘The emergency relating to software-defined networking (SDN), especially in terms of the prototype associated with OpenFlow, provides new possibilities for innovating on network design. Researchers have started to extend SDN to cellular networks. Such new programmable architecture is beneficial to the evolution of mobile networks and allows operators to provide better services. The typical cellular network comprises radio access network (RAN) and core network (CN); hence, the technique roadmap diverges in two ways. In this paper, we investigate SoftRAN, the latest SDN solution for RAN, and SoftCell and MobileFlow, the latest solutions for CN. We also define a series of control functions for CROWD. Unlike in the other literature, we emphasize only softwaredefined cellular network solutions and specifications in order to provide possible research directions.
文摘The developing mobile technologies have resulted in operators focusing on how to optimize their 2G networks and ensure a smooth network end, there are two approaches for upgrade: one core network with a 2G-radio network, while the other is (Mobile Switching Center) with WCDMA MSCS (Mobile Gateway) to optimize the Core network hierararchy
文摘ZTE Corporation, a leading global provider of telecommunications equipment and network solutions, announced on April 26, 2010 that it has been chosen by China Mobile to deliver its IMS core network in key Chinese provinces. The China Mobile' s commercial IMS network will boast 1.4 million lines when it is completed in three months. According to the comprehensive evaluation process by China Mobile, ZTE was ranked among the tier one IMS supplier group for the project this time.
文摘27 August 2012--ZTE Corporation has signed a deal on a packet-switched core network (CN) for KPN Group Belgium (KPNGB). KPNGB will deploy ZTE's packet-switched CN equipment, which supports unified radio access. The contract is the second of its kind between ZTE and KPNfollows from a construction project with KPN Germany (E-Plus) that was completed in September 2010.
文摘This article presents the network design schemes of CERNET2 including overall architecture, the backbone, core nodes, access solutions and the CNGI peer centers. CERNET2 connects 25 core nodes distributed in 20 cities of China at the speed of 2.5-10 Gb/s. CERNET2 has four unique features. First, its backbone adopts native IPv6 protocols, rather than IPv4/IPv6 dual stack. It is the largest pure IPv6 network in the world. Second, it provides an environment for testing and trial operation of China-made IPv6 core routers. It also allows tests of interconnection, interworking and interoperation among multiple vendors. Third, the large IPv6 address space enables the study on network addresses in a real network environment, which ensures the construction of a secured and trusted CNGI. Last, it is a test-bed for NGI applications.
文摘As the railway sector intensifies its efforts in the technology research,system R&D and technology application of 5G-R,the paper conducts a preliminary study on its application frequency in terms of its frequency propagation,network carrying capacity,its ability to work as industrial pillar,system applicability,and the compatibility of 5G-R with other systems.In line with China's GSM-R application practice and the application needs,the paper focuses on the study of key technologies such as model alignment of base station equipment,and optimization of 5G-R terminal and core network,identifying the priorities for the China's efforts to develop 5G-R and providing references for the research and application of related technologies.
基金Capital project for application and promotion of clinical researches(No.Z171100001017123)Capital specialized scientific research proect of health development for young excellent talents(No.2018-4-4078)。
文摘Objective:Based on data mining software,applying frequent itemsets,association rules,hierarchical clustering,complex networks and other data mining methods to analyze the usage and compatibility of traditional Chinese medicine(TCM)patent compound for functional dyspepsia.Method:Use the Chinese patent database to search the compound for the treatment of functional dyspepsia,exclude traditional Chinese medicine extracts,single drugs,combined use of Chinese and Western medicines,etc.,screen the patented compound of TCM,establish an Excel data table,and apply data mining software to The data is subjected to frequency statistics,association rules,cluster analysis and complex network analysis.Result:A total of 238 prescriptions for functional dyspepsia were screened.The four qi of the drugs were mainly warm and calm,the five flavors were mainly sweet and spicy,and the spleen and stomach were the main meridians.The top 10 Chinese medicines with higher frequency are Shanzha、Chenpi、Gancao、Maiya、Jineijin、Fuling、Baizhu、Shenqu、Houpo、Banxia;frequent itemsets show that the drugs are mainly compatible with qi and spleen,qi and digestion;association rules The analysis shows that the common drug pairs used in the treatment of functional dyspepsia include Chenpi-Shanzha、Maiya-Shanzha、Jineijin-Shanzha,etc.;cluster analysis found that there are 4 types of drugs for functional dyspepsia,mainly including drugs for regulating qi-flowing for harmonizing stomach,drugs for soothing liver and promoting Qi,drugs for eliminating food and resolving accumulation,drugs for benefiting qi and strengthening spleen;the 22-flavor Chinese medicine in the core drug network,the core compatibility is mainly to eliminate stagnation and spleen.Conclusion:Data mining research provides a reference for the clinical treatment of functional dyspepsia and the development of TCM formulas;Clinical treatment of functional dyspepsia should grasp the basic principles of strengthening vital energy and eliminating pathogenic factors to benefit qi,strengthen the spleen,and eliminate food.It is a basic treatment method,taking into account the methods of regulating qi-flowing for harmonizing stomach,soothing the liver and relieving depression,relieving dampness and dampness,and combining the specific conditions of patients with syndrome differentiation and treatment.
基金Beijing Municipal Administration of Traditional Chinese Medicine Project(No.2019-ZX-005)。
文摘Objective:Based on the data mining method,explore the medication rules of Chinese patent medicines for the treatment of digestive system tumors.Method:Based on the"Chinese Traditional Medicine Prescription Database"in https://db.yaozh.com/,collect Chinese patent medicines for the treatment of digestive system tumors,establish an Excel table,and use the ancient and modern medical case cloud platform(V2.2.1)to perform frequency statistics,association rules,and drugs on the data Clustering and complex network analysis.Results:A total of 36 Chinese patent medicines for the treatment of digestive system tumors were screened.The medicinal properties were mainly warm and cold,the taste was bitter and sweet,and the meridians were mainly liver and spleen meridians.High frequency Chinese medicine include Astragalus,Scutellaria-barbata,Ginseng,Curcuma,Triangle,Atractylodes,Hedyotis diffusa,etc.Correlation analysis obtained 17 drug combinations,High-frequency drug pairs include Scutellaria-barbata-Astragalus,Ginseng-Astragalus,Curcuma-Astragalus,Scutellaria-barbata-Curcuma,etc.Cluster analysis found 3 types of drugs.The core drug network is composed of 27 drugs,and the core compatibility network consists of 3 groups of drugs.Conclusion:The Chinese patent compound medicine for the treatment of digestive system tumors has the characteristics of combining cold and warming,replenishing and reducing treatment,and treating the liver and spleen at the same time.The medicine is mainly used to replenish qi and invigorate the spleen,promote blood circulation and remove blood stasis,and clear away heat and detoxification.Replenish qi,nourish yin,invigorate blood,and detoxify are mainly compatible with each other,reflecting the pathogenesis characteristics of"deficiency,stasis,and toxin"in digestive system tumors.Data mining can provide references for the prescription and compatibility of Chinese patent medicines.
基金the National Key Research and Development Program of China(Nos.2020YFB1806607 and 2022YFB2902202)the National Natural Science Foundation of China(Nos.61521003 and 61701538)。
文摘The sixth-generation mobile communication(6G)networks will face more complex endogenous security problems,and it is urgent to propose new universal security theories and establish new practice norms to deal with theªunknown unknownºsecurity threats in cyberspace.This paper first expounds the new paradigm of cyberspace endogenous security and introduces the vision of 6G cyberspace security.Then,it analyzes the security problems faced by the 6G core network,wireless access network,and emerging associated technologies in detail,as well as the corresponding security technology development status and the integrated development of endogenous security and traditional security.Furthermore,this paper describes the relevant security theories and technical concepts under the guidance of the new paradigm of endogenous security.
基金supported by the National Science and Technology Major Project (2018ZX03001016)the China Ministry of Education-CMCC Research (MCM20160104 )the Beijing Municipal Science and Technology Commission Research (Z171100005217001)
文摘The explosive increase of smart devices and mobile traffic results intolerable network latency and degraded service to the end-users. in heavy burden on backhaul and core network, As a complement to core network, edge network contributes to relieving network burden and improving user experience. To investigate the problem of optimizing the total consumption in an edge-core network, the system consumption minimization problem is fromulated, considering the energy consumption and delay. Given that the formulated problem is a mixed nonlinear integer programming (MNIP) , a low-complexity workload allocation algorithm is proposed based on interior-point method. The proposed algorithm has an extremely short running time in practice. Finally, simulation results show that edge network can significantly complement core network with much reduced backhaul energy consumption and delay.
文摘Determining effective traditional Chinese medicine (TCM) treatments for specific disease conditions or particular patient groups is a difficult issue that necessitates investigation because of the complicated personalized manifestations in real-world patients and the individualized combination therapies prescribed in clinical settings. In this study, a multistage analysis method that integrates propensity case matching, complex network analysis, and herb set enrichment analysis was proposed to identify effective herb prescriptions for particular diseases (e.g., insomnia). First, propensity case matching was applied to match clinical cases. Then, core network extraction and herb set enrichment were combined to detect core effective herb prescriptions. Effectiveness-based mutual information was used to detect strong herb symptom relationships. This method was applied on a TCM clinical data set with 955 patients collected from well-designed observational studies. Results revealed that groups of herb prescriptions with higher effectiveness rates (76.9% vs. 42.8% for matched samples; 94.2% vs. 84.9% for all samples) compared with the original prescriptions were found. Particular patient groups with symptom manifestations were also identified to help investigate the indications of the effective herb prescriptions.