The Arkhangelsk Seismic Network(ASN)of the N.Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences,founded in 2003,includes 10 permanent seismic stations located o...The Arkhangelsk Seismic Network(ASN)of the N.Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences,founded in 2003,includes 10 permanent seismic stations located on the coasts of the White,Barents,and Kara Seas and on the Arctic archipelagos of Novaya Zemlya,Franz Josef Land,and Severnaya Zemlya.The network is registered with the International Federation of Digital Seismograph Networks and the International Seismological Center.We used not only ASN data to process earthquakes but also the waveforms of various international seismic stations.The 13,000 seismic events were registered using ASN data for 2012-2022,and for 5,500 of them,we determined the parameters of the earthquake epicenters from the European Arctic.The spatial distribution of epicenters shows that the ASN monitors not only the main seismically active zones but also weak seismicity on the shelf of the Barents and Kara Seas.The representative magnitude of ASN was ML,rep=3.5.The level of microseismic noise has seasonal variations that affect the registration capabilities of each station included in the ASN and the overall sensitivity of the network as a whole.In summer,the sensitivity of the ASN decreased owing to the increasing microseismic and ambient noises,whereas in winter,the sensitivity of the ASN increased significantly because of the decrease.展开更多
As biomarkers are important in the early diagnosis ofAlzheimer’s disease （AD）, the frst collab-orative work of recruiting early-onset familial AD （EO-FAD） families in Canada and China was initiated in 2012. The r...As biomarkers are important in the early diagnosis ofAlzheimer’s disease （AD）, the frst collab-orative work of recruiting early-onset familial AD （EO-FAD） families in Canada and China was initiated in 2012. The registration networks have collected hundreds of pedigrees, for which genetic screening, neuropsycholog-ical tests and amyloid and tau imaging was used to study diagnostic biomarkers for preclinical and mild cognitive impairment （MCI） stages of AD. Besides identifying ped-igrees with novel mutations in presenilins （PSENs）/amy-loid precursor protein （APP）, the program has benefted training of Chinese research fellows, AD clinical trials forprevention,the ethical concernsfor clinical fndings, and other collaborative projects with Chinese investiga-tors. Further research of the collaborative program may facilitate the testing and clinical use of novel treatments for EOFAD and late onset AD and contribute to dementia prevention strategies in Canada and China.展开更多
基金supported by the Russian Federation Ministry of Science and Higher Education Research project N 122011300389-8.
文摘The Arkhangelsk Seismic Network(ASN)of the N.Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences,founded in 2003,includes 10 permanent seismic stations located on the coasts of the White,Barents,and Kara Seas and on the Arctic archipelagos of Novaya Zemlya,Franz Josef Land,and Severnaya Zemlya.The network is registered with the International Federation of Digital Seismograph Networks and the International Seismological Center.We used not only ASN data to process earthquakes but also the waveforms of various international seismic stations.The 13,000 seismic events were registered using ASN data for 2012-2022,and for 5,500 of them,we determined the parameters of the earthquake epicenters from the European Arctic.The spatial distribution of epicenters shows that the ASN monitors not only the main seismically active zones but also weak seismicity on the shelf of the Barents and Kara Seas.The representative magnitude of ASN was ML,rep=3.5.The level of microseismic noise has seasonal variations that affect the registration capabilities of each station included in the ASN and the overall sensitivity of the network as a whole.In summer,the sensitivity of the ASN decreased owing to the increasing microseismic and ambient noises,whereas in winter,the sensitivity of the ASN increased significantly because of the decrease.
文摘As biomarkers are important in the early diagnosis ofAlzheimer’s disease （AD）, the frst collab-orative work of recruiting early-onset familial AD （EO-FAD） families in Canada and China was initiated in 2012. The registration networks have collected hundreds of pedigrees, for which genetic screening, neuropsycholog-ical tests and amyloid and tau imaging was used to study diagnostic biomarkers for preclinical and mild cognitive impairment （MCI） stages of AD. Besides identifying ped-igrees with novel mutations in presenilins （PSENs）/amy-loid precursor protein （APP）, the program has benefted training of Chinese research fellows, AD clinical trials forprevention,the ethical concernsfor clinical fndings, and other collaborative projects with Chinese investiga-tors. Further research of the collaborative program may facilitate the testing and clinical use of novel treatments for EOFAD and late onset AD and contribute to dementia prevention strategies in Canada and China.
