At present,depression is treated with antidepressant drugs and assisted with psychotherapy and physical therapy,and these expensive and time-consuming treatment methods often end prematurely and result in a prolonged ...At present,depression is treated with antidepressant drugs and assisted with psychotherapy and physical therapy,and these expensive and time-consuming treatment methods often end prematurely and result in a prolonged course w ithout effective symptom relief. Therefore,based on the neurofeedback therapy,a novel depression rehabilitation method using a Virtual-Reality(VR) game framew ork is proposed. In this VR game framew ork,an innovative threeelectrode Electroencephalography(EEG) collector is used to record patients' EEG data. The data are processed and converted into feedback features,and the feedback w ill be displayed to patients in real time through a VR headset. Patients can adjust their psychological activity based on the feedback,and relieve their physiological dysfunction effectively. The framew ork also provides a data storage module,w hich may offer therapists w ays to assess patients' rehabilitation results in a long term,as w ell as provide possibility to continue tow ards better algorithm of feedback features w ith data-mining.The prototype system is tested in the framew ork,and the experimental results prove the effectiveness of the framew ork in depression rehabilitation.展开更多
Real-time functional magnetic resonance imaging (rtfMRI) technology has been widely used to train subjects to actively regulate the activity of specific brain regions. Although many previous studies have demonstrated ...Real-time functional magnetic resonance imaging (rtfMRI) technology has been widely used to train subjects to actively regulate the activity of specific brain regions. Although many previous studies have demonstrated that neurofeedback training alters the functional connectivity between brain regions in the task state and resting state, it is unclear how the regulation of the key hub of the default mode network (DMN) affects the topological properties of the resting-state brain network. The current study aimed to investigate what topological changes would occur in the large-scale intrinsic organization of the resting state after the real-time down-regulation of the posterior cingulate cortex (PCC). The results indicated that the down-regulation of the PCC in the DMN reduced the functional connectivity of the PCC with the nodes outside of the DMN and reduced functional connectivity between the superior medial frontal gyrus (SFGmed) and parahippocampal gyrus (PHG) in the experimental group. Moreover, the nodal graph properties of the SFGmed were reduced, while that of the PHG showed the opposite alteration after the down-regulation of the PCC. These findings possibly suggest that the regulation of the key hub of the DMN, the PCC, mainly changed the information transfer of the SFGmed and PHG.展开更多
BACKGROUND Chronic insomnia affects about 6%-13% of the Canadian population.Although treatments already exist,they each have their own issues.Neurofeedback is a neuromodulation technique that specifically targets abno...BACKGROUND Chronic insomnia affects about 6%-13% of the Canadian population.Although treatments already exist,they each have their own issues.Neurofeedback is a neuromodulation technique that specifically targets abnormal brain activity and is gaining attention as a possible insomnia treatment.AIM To review the latest studies pertaining to the use of neurofeedback in the treatment of insomnia.METHODS In this non-systematic review,only experimental studies assessing the effects of neurofeedback on patients with insomnia were targeted across four bibliographic databases.RESULTS A total of 12 studies were retained.All neurofeedback studies included in this study showed a clear improvement of subjective sleep.However,data concerning objective improvement are contradictory.Most studies regarding surface and zscore neurofeedback show that neurofeedback targeting the sensorimotor rhythm in the sensorimotor cortex may help improve subjective sleep.A placebo effect seems also to be present in some studies.Several limitations were present in each study.CONCLUSION While studies concerning neurofeedback as a treatment for insomnia are encouraging,many methodological barriers remain to be resolved to prove its efficacy unequivocally.More studies using robust design parameters,as well as the replication of existing studies,are necessary to support neurofeedback as an effective treatment for insomnia.展开更多
Recent studies describe a number of difficulties associated with attention deficit in children with reading disabilities. Information about visual-spatial attention mainly arises from studies using event-related poten...Recent studies describe a number of difficulties associated with attention deficit in children with reading disabilities. Information about visual-spatial attention mainly arises from studies using event-related potentials (ERPs) during Posner’s spatial cueing paradigm. This study aims to use neurofeedback with a special protocol for treating children with reading disabilities, and moreo-ver, to evaluate visual-spatial attention ability by means of Posner paradigm task and ERPs. The study was conducted in a single subject design in 20 sessions. Participants were 2 male children, aged between 10 - 12 years old, who completed twelve 30-min neurofeedback sessions. Repeated measurements were performed during the baseline, treatment, and post treatment phases. Results showed some improvement in Posner paradigm parameters (correct response, valid and invalid reaction times). Furthermore, grand average ERPs for both of the participants in each of the four conditions (Valid-right, Invalid-right, Valid-left and Invalid-left) were analyzed. The analysis of P3 component showed a reduction in latency, indicating an improvement in the timing of cognitive processes. In addition, the graphs showed a decrease in amplitude level, which meant easier processing than before.展开更多
Although there is no consensus with respect to that if exposed Extremely Low Frequency Magnetic Field (ELF-MF) affects human brain activity for guidelines of brain management, there are some evidences related with hum...Although there is no consensus with respect to that if exposed Extremely Low Frequency Magnetic Field (ELF-MF) affects human brain activity for guidelines of brain management, there are some evidences related with human attention changes. Therefore, this study evaluates the effects of 45 Hz sinusoidal ELF (360 μT) at Cz regions, cantered at dominant frequency using Electroencephalogram (EEG) analysis. The purpose was to extracte transient or permanent events as an index for new neurofeedback (NF) system improvement. Twenty-four healthy volunteers aged between 20 and 28 years of age were randomly assigned to one of two groups, which differed in the type of NF training concerning the exposed and non-exposed magnetic field effect on performance in attention tests during NF. Results indicate that theta and beta EEG rhythms variations in exposed group changed more significantly in comparison of traditional NF展开更多
Introduction:?Enuresis is one of the most common psychiatric disorders in children. Classical?treatments for primary enuretic children are conditioning (Bell and Pad method, and drug therapy). Neurofeedback is a kind ...Introduction:?Enuresis is one of the most common psychiatric disorders in children. Classical?treatments for primary enuretic children are conditioning (Bell and Pad method, and drug therapy). Neurofeedback is a kind of conditioning by changing amplitudes of brain waves. Method: Three?groups of 10 enuretic children were selected randomly. All three groups took imipramine. The?first group also took neurofeedback sessions with protocol of enhancement of?β/θ?wave ratio in occipital zone. The second group took non-real neurofeedback sessions beside the drug. The third?group just took the drug. Result:?All three groups showed significant remission (P < 0.0001) after treatment and a three-month follow-up. Conclusion:?Neurofeedback by this protocol was not any more efficient than imipramine therapy by itself.展开更多
Introduction: Relapse in methamphetamine dependency is one of the most difficult parts to treat. Therefore treatment of craving for usage is one of the essential sections of treatment in methamphetamine dependency (ad...Introduction: Relapse in methamphetamine dependency is one of the most difficult parts to treat. Therefore treatment of craving for usage is one of the essential sections of treatment in methamphetamine dependency (addiction). This study evaluates the effect of neurofeedback therapy on craving for use. Methods: In this study 20 male patient with methamphetamine dependency who diagnosed on the basis of DSM-V were selected. None of the patients had any psychiatric and neurologic disorder except addiction of methamphetamine. Patients were divided into 2 groups of 10. The first group has taken real neurofeedback therapy sessions while the second has undergone non-real neurofeedback (sham) therapy. Then the two groups have been compared with t-test. Result: The result shows that in the first group (real neurofeedback), craving for methamphetamine use has been decreased significantly whereas in the second group (non-real or sham), the decrease was not significant. Conclusion: Neurofeedback therapy is effective in treatment of craving for methamphetamine use.展开更多
Biofeedback is used to treat the mental diseases of college students, such as test anxiety, depression, personality, and mood. Anxiety of the colleague students was first tested by test anxiety scale （TAS） and then ...Biofeedback is used to treat the mental diseases of college students, such as test anxiety, depression, personality, and mood. Anxiety of the colleague students was first tested by test anxiety scale （TAS） and then treated by biofeedback. After getting the biofeedback treatment, the students＇ TAS scores, blood volume pulse, and skin conductance were decreased, especially, their TAS scores dropped markedly. Meanwhile, the level of EEG （61 rhythm/a rhythm） and peripheral temperature increased observably. Then, neurofeedbaek （β1 rhythm/α rhythm） was applied to treat students＇ depression, personality, and mood. As a result, these three kinds of symptoms got alleviated. And their therapeutic effects based on neurofeedback were more stable, durative and less reerudescent.展开更多
Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks,which have been widely applied in the field of central neurological diseases,such as stroke,Parkinson...Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks,which have been widely applied in the field of central neurological diseases,such as stroke,Parkinson’s disease,and mental disorders.Although significant advances have been made in neuromodulation technologies,the identification of optimal neurostimulation paramete rs including the co rtical target,duration,and inhibition or excitation pattern is still limited due to the lack of guidance for neural circuits.Moreove r,the neural mechanism unde rlying neuromodulation for improved behavioral performance remains poorly understood.Recently,advancements in neuroimaging have provided insight into neuromodulation techniques.Functional near-infrared spectroscopy,as a novel non-invasive optical brain imaging method,can detect brain activity by measuring cerebral hemodynamics with the advantages of portability,high motion tole rance,and anti-electromagnetic interference.Coupling functional near-infra red spectroscopy with neuromodulation technologies offe rs an opportunity to monitor the cortical response,provide realtime feedbac k,and establish a closed-loop strategy integrating evaluation,feedbac k,and intervention for neurostimulation,which provides a theoretical basis for development of individualized precise neuro rehabilitation.We aimed to summarize the advantages of functional near-infra red spectroscopy and provide an ove rview of the current research on functional near-infrared spectroscopy in transcranial magnetic stimulation,transcranial electrical stimulation,neurofeedback,and braincomputer interfaces.Furthermore,the future perspectives and directions for the application of functional near-infrared spectroscopy in neuromodulation are summarized.In conclusion,functional near-infrared spectroscopy combined with neuromodulation may promote the optimization of central pellral reorganization to achieve better functional recovery form central nervous system diseases.展开更多
肥胖症及减重后不能维持健康体质量的核心因素多为食物成瘾,食物成瘾在神经影像学中表现为奖赏网络与认知控制网络间神经环路的失衡。实时功能磁共振成像神经反馈(real time functional magnetic resonance imaging neurofeedback,rtfMR...肥胖症及减重后不能维持健康体质量的核心因素多为食物成瘾,食物成瘾在神经影像学中表现为奖赏网络与认知控制网络间神经环路的失衡。实时功能磁共振成像神经反馈(real time functional magnetic resonance imaging neurofeedback,rtfMRI-NF)作为一种新型生物反馈技术,已被应用于其他物质成瘾领域的临床研究和治疗中。在食物成瘾肥胖症中,rtfMRI-NF同样具有重塑异常脑功能、改善摄食行为并达到减重效果的潜力。本综述总结了肥胖患者食物成瘾的功能磁共振脑成像模型,探讨应用rtfMRI-NF作为其潜在治疗工具的可行神经靶点,并回顾了rtfMRI-NF在肥胖应用中的最新研究进展,为未来rtfMRI-NF在肥胖中的治疗策略和临床指导提供参考。展开更多
Neurofeedback or electroencephalogram(EEG) biofeedback technology is widely used in clinical rehabilitation field. In this paper, we used a brain-computer interface(BCI) neurofeedback system for attention deficit hype...Neurofeedback or electroencephalogram(EEG) biofeedback technology is widely used in clinical rehabilitation field. In this paper, we used a brain-computer interface(BCI) neurofeedback system for attention deficit hyperactivity disorder(ADHD) children treatment.After 20 training sessions, integrated visual and auditory-conhnuous performance test(IVA-CPT), DSM-IV and conner scale results suggested that the attention ofsubjectshad been strengthened, which showed that the BCI neurofeedback system could provide an effective therapyfor treating ADHDchildren.展开更多
目的基于《国际疾病分类第十一次修订本》(ICD-11)和《国际功能、残疾和健康分类》(ICF)系统综述神经反馈训练对老年人大脑认知功能的影响。方法构建PICO架构,检索建库至2023年7月PubMed、Web of Science、ProQuest和中国知网有关神经...目的基于《国际疾病分类第十一次修订本》(ICD-11)和《国际功能、残疾和健康分类》(ICF)系统综述神经反馈训练对老年人大脑认知功能的影响。方法构建PICO架构,检索建库至2023年7月PubMed、Web of Science、ProQuest和中国知网有关神经反馈训练对老年人认知干预的随机对照试验,采用物理治疗证据数据库量表对纳入的文献进行方法质量学评价,并进行系统综述。结果纳入文献15篇,分别来自10个国家,共计520例被试。纳入研究的被试包括健康老年人和轻度认知障碍老年人,所涉及的神经反馈波形有α波、β波、θ波、β/α波、感觉运动节律波;干预时长为20~90 min,干预频率有12周30次的长期干预,也有1周8次的短期高频干预;健康结局集中体现于认知功能方面,包括记忆功能、注意功能、抑制控制功能和执行功能。结论神经反馈训练有助于改善老年人认知功能,缓解认知老化。展开更多
基金National Basic Research Program of China(2014CB744600)National Natural Science Foundation of China(61632014,61210010)+2 种基金Program of Beijing M unicipal Science&Technology Commission(Z171100000117005)Program of International S&T Cooperation of M OST(2013DFA11140)National Key Research and Development Program of China(2016YFC1307203)
文摘At present,depression is treated with antidepressant drugs and assisted with psychotherapy and physical therapy,and these expensive and time-consuming treatment methods often end prematurely and result in a prolonged course w ithout effective symptom relief. Therefore,based on the neurofeedback therapy,a novel depression rehabilitation method using a Virtual-Reality(VR) game framew ork is proposed. In this VR game framew ork,an innovative threeelectrode Electroencephalography(EEG) collector is used to record patients' EEG data. The data are processed and converted into feedback features,and the feedback w ill be displayed to patients in real time through a VR headset. Patients can adjust their psychological activity based on the feedback,and relieve their physiological dysfunction effectively. The framew ork also provides a data storage module,w hich may offer therapists w ays to assess patients' rehabilitation results in a long term,as w ell as provide possibility to continue tow ards better algorithm of feedback features w ith data-mining.The prototype system is tested in the framew ork,and the experimental results prove the effectiveness of the framew ork in depression rehabilitation.
文摘Real-time functional magnetic resonance imaging (rtfMRI) technology has been widely used to train subjects to actively regulate the activity of specific brain regions. Although many previous studies have demonstrated that neurofeedback training alters the functional connectivity between brain regions in the task state and resting state, it is unclear how the regulation of the key hub of the default mode network (DMN) affects the topological properties of the resting-state brain network. The current study aimed to investigate what topological changes would occur in the large-scale intrinsic organization of the resting state after the real-time down-regulation of the posterior cingulate cortex (PCC). The results indicated that the down-regulation of the PCC in the DMN reduced the functional connectivity of the PCC with the nodes outside of the DMN and reduced functional connectivity between the superior medial frontal gyrus (SFGmed) and parahippocampal gyrus (PHG) in the experimental group. Moreover, the nodal graph properties of the SFGmed were reduced, while that of the PHG showed the opposite alteration after the down-regulation of the PCC. These findings possibly suggest that the regulation of the key hub of the DMN, the PCC, mainly changed the information transfer of the SFGmed and PHG.
文摘BACKGROUND Chronic insomnia affects about 6%-13% of the Canadian population.Although treatments already exist,they each have their own issues.Neurofeedback is a neuromodulation technique that specifically targets abnormal brain activity and is gaining attention as a possible insomnia treatment.AIM To review the latest studies pertaining to the use of neurofeedback in the treatment of insomnia.METHODS In this non-systematic review,only experimental studies assessing the effects of neurofeedback on patients with insomnia were targeted across four bibliographic databases.RESULTS A total of 12 studies were retained.All neurofeedback studies included in this study showed a clear improvement of subjective sleep.However,data concerning objective improvement are contradictory.Most studies regarding surface and zscore neurofeedback show that neurofeedback targeting the sensorimotor rhythm in the sensorimotor cortex may help improve subjective sleep.A placebo effect seems also to be present in some studies.Several limitations were present in each study.CONCLUSION While studies concerning neurofeedback as a treatment for insomnia are encouraging,many methodological barriers remain to be resolved to prove its efficacy unequivocally.More studies using robust design parameters,as well as the replication of existing studies,are necessary to support neurofeedback as an effective treatment for insomnia.
文摘Recent studies describe a number of difficulties associated with attention deficit in children with reading disabilities. Information about visual-spatial attention mainly arises from studies using event-related potentials (ERPs) during Posner’s spatial cueing paradigm. This study aims to use neurofeedback with a special protocol for treating children with reading disabilities, and moreo-ver, to evaluate visual-spatial attention ability by means of Posner paradigm task and ERPs. The study was conducted in a single subject design in 20 sessions. Participants were 2 male children, aged between 10 - 12 years old, who completed twelve 30-min neurofeedback sessions. Repeated measurements were performed during the baseline, treatment, and post treatment phases. Results showed some improvement in Posner paradigm parameters (correct response, valid and invalid reaction times). Furthermore, grand average ERPs for both of the participants in each of the four conditions (Valid-right, Invalid-right, Valid-left and Invalid-left) were analyzed. The analysis of P3 component showed a reduction in latency, indicating an improvement in the timing of cognitive processes. In addition, the graphs showed a decrease in amplitude level, which meant easier processing than before.
文摘Although there is no consensus with respect to that if exposed Extremely Low Frequency Magnetic Field (ELF-MF) affects human brain activity for guidelines of brain management, there are some evidences related with human attention changes. Therefore, this study evaluates the effects of 45 Hz sinusoidal ELF (360 μT) at Cz regions, cantered at dominant frequency using Electroencephalogram (EEG) analysis. The purpose was to extracte transient or permanent events as an index for new neurofeedback (NF) system improvement. Twenty-four healthy volunteers aged between 20 and 28 years of age were randomly assigned to one of two groups, which differed in the type of NF training concerning the exposed and non-exposed magnetic field effect on performance in attention tests during NF. Results indicate that theta and beta EEG rhythms variations in exposed group changed more significantly in comparison of traditional NF
文摘Introduction:?Enuresis is one of the most common psychiatric disorders in children. Classical?treatments for primary enuretic children are conditioning (Bell and Pad method, and drug therapy). Neurofeedback is a kind of conditioning by changing amplitudes of brain waves. Method: Three?groups of 10 enuretic children were selected randomly. All three groups took imipramine. The?first group also took neurofeedback sessions with protocol of enhancement of?β/θ?wave ratio in occipital zone. The second group took non-real neurofeedback sessions beside the drug. The third?group just took the drug. Result:?All three groups showed significant remission (P < 0.0001) after treatment and a three-month follow-up. Conclusion:?Neurofeedback by this protocol was not any more efficient than imipramine therapy by itself.
文摘Introduction: Relapse in methamphetamine dependency is one of the most difficult parts to treat. Therefore treatment of craving for usage is one of the essential sections of treatment in methamphetamine dependency (addiction). This study evaluates the effect of neurofeedback therapy on craving for use. Methods: In this study 20 male patient with methamphetamine dependency who diagnosed on the basis of DSM-V were selected. None of the patients had any psychiatric and neurologic disorder except addiction of methamphetamine. Patients were divided into 2 groups of 10. The first group has taken real neurofeedback therapy sessions while the second has undergone non-real neurofeedback (sham) therapy. Then the two groups have been compared with t-test. Result: The result shows that in the first group (real neurofeedback), craving for methamphetamine use has been decreased significantly whereas in the second group (non-real or sham), the decrease was not significant. Conclusion: Neurofeedback therapy is effective in treatment of craving for methamphetamine use.
基金supported by the New Century Excellent Talents in University
文摘Biofeedback is used to treat the mental diseases of college students, such as test anxiety, depression, personality, and mood. Anxiety of the colleague students was first tested by test anxiety scale （TAS） and then treated by biofeedback. After getting the biofeedback treatment, the students＇ TAS scores, blood volume pulse, and skin conductance were decreased, especially, their TAS scores dropped markedly. Meanwhile, the level of EEG （61 rhythm/a rhythm） and peripheral temperature increased observably. Then, neurofeedbaek （β1 rhythm/α rhythm） was applied to treat students＇ depression, personality, and mood. As a result, these three kinds of symptoms got alleviated. And their therapeutic effects based on neurofeedback were more stable, durative and less reerudescent.
文摘Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks,which have been widely applied in the field of central neurological diseases,such as stroke,Parkinson’s disease,and mental disorders.Although significant advances have been made in neuromodulation technologies,the identification of optimal neurostimulation paramete rs including the co rtical target,duration,and inhibition or excitation pattern is still limited due to the lack of guidance for neural circuits.Moreove r,the neural mechanism unde rlying neuromodulation for improved behavioral performance remains poorly understood.Recently,advancements in neuroimaging have provided insight into neuromodulation techniques.Functional near-infrared spectroscopy,as a novel non-invasive optical brain imaging method,can detect brain activity by measuring cerebral hemodynamics with the advantages of portability,high motion tole rance,and anti-electromagnetic interference.Coupling functional near-infra red spectroscopy with neuromodulation technologies offe rs an opportunity to monitor the cortical response,provide realtime feedbac k,and establish a closed-loop strategy integrating evaluation,feedbac k,and intervention for neurostimulation,which provides a theoretical basis for development of individualized precise neuro rehabilitation.We aimed to summarize the advantages of functional near-infra red spectroscopy and provide an ove rview of the current research on functional near-infrared spectroscopy in transcranial magnetic stimulation,transcranial electrical stimulation,neurofeedback,and braincomputer interfaces.Furthermore,the future perspectives and directions for the application of functional near-infrared spectroscopy in neuromodulation are summarized.In conclusion,functional near-infrared spectroscopy combined with neuromodulation may promote the optimization of central pellral reorganization to achieve better functional recovery form central nervous system diseases.
文摘肥胖症及减重后不能维持健康体质量的核心因素多为食物成瘾,食物成瘾在神经影像学中表现为奖赏网络与认知控制网络间神经环路的失衡。实时功能磁共振成像神经反馈(real time functional magnetic resonance imaging neurofeedback,rtfMRI-NF)作为一种新型生物反馈技术,已被应用于其他物质成瘾领域的临床研究和治疗中。在食物成瘾肥胖症中,rtfMRI-NF同样具有重塑异常脑功能、改善摄食行为并达到减重效果的潜力。本综述总结了肥胖患者食物成瘾的功能磁共振脑成像模型,探讨应用rtfMRI-NF作为其潜在治疗工具的可行神经靶点,并回顾了rtfMRI-NF在肥胖应用中的最新研究进展,为未来rtfMRI-NF在肥胖中的治疗策略和临床指导提供参考。
基金Produce-Study-Research program,Guangdong Province and Ministry of Educationgrant number:2008809050023
文摘Neurofeedback or electroencephalogram(EEG) biofeedback technology is widely used in clinical rehabilitation field. In this paper, we used a brain-computer interface(BCI) neurofeedback system for attention deficit hyperactivity disorder(ADHD) children treatment.After 20 training sessions, integrated visual and auditory-conhnuous performance test(IVA-CPT), DSM-IV and conner scale results suggested that the attention ofsubjectshad been strengthened, which showed that the BCI neurofeedback system could provide an effective therapyfor treating ADHDchildren.
文摘目的基于《国际疾病分类第十一次修订本》(ICD-11)和《国际功能、残疾和健康分类》(ICF)系统综述神经反馈训练对老年人大脑认知功能的影响。方法构建PICO架构,检索建库至2023年7月PubMed、Web of Science、ProQuest和中国知网有关神经反馈训练对老年人认知干预的随机对照试验,采用物理治疗证据数据库量表对纳入的文献进行方法质量学评价,并进行系统综述。结果纳入文献15篇,分别来自10个国家,共计520例被试。纳入研究的被试包括健康老年人和轻度认知障碍老年人,所涉及的神经反馈波形有α波、β波、θ波、β/α波、感觉运动节律波;干预时长为20~90 min,干预频率有12周30次的长期干预,也有1周8次的短期高频干预;健康结局集中体现于认知功能方面,包括记忆功能、注意功能、抑制控制功能和执行功能。结论神经反馈训练有助于改善老年人认知功能,缓解认知老化。
