The aspect ratio of the structure has a significant impact on the overall stability of the ultra high-rise building. A large aspect ratio of the structure increases the risk of overturning and reduces the lateral stif...The aspect ratio of the structure has a significant impact on the overall stability of the ultra high-rise building. A large aspect ratio of the structure increases the risk of overturning and reduces the lateral stiffness of the structure, leading to significant tensile and compressive stresses in the isolated bearings. To study the effect of aspect ratio on the seismic response and overturning resistance of a new staggered story isolated structure, three models with different aspect ratios were established. Nonlinear time-history analysis of the three models was conducted using ETABS finite element software. The results indicate that the overturning moment and overturning resistance moment of the superstructure in the new staggered story isolated structure increase with an increasing aspect ratio. However, the increase in the overturning moment of the superstructure is much greater than the increase in the overturning resistance moment, resulting in a decrease in the overturning resistance ratio of the superstructure with an increasing aspect ratio. The overturning moment and overturning resistance moment of the substructure in the new staggered story isolated structure decrease with an increasing aspect ratio. However, the decrease in the overturning moment of the substructure is greater than the decrease in the overturning resistance moment, leading to an increase in the overturning resistance ratio of the substructure with an increasing aspect ratio. The decrease in the overturning resistance ratio of the superstructure in the new staggered story isolated structure is much greater than the increase in the overturning resistance ratio of the substructure. Therefore, as the aspect ratio of the overall structure increases, the overturning resistance ratio of the superstructure and the entire structure decreases.展开更多
The band structure,DOSs,and optical properties of(Y_(0.75)Ca_(0.25))(Cu_(0.75)Mn_(0.25))SO,including dielectric function,absorption function,reflection function,and energy loss spectrum were studied by using the first...The band structure,DOSs,and optical properties of(Y_(0.75)Ca_(0.25))(Cu_(0.75)Mn_(0.25))SO,including dielectric function,absorption function,reflection function,and energy loss spectrum were studied by using the first-principles calculation.The calculation results indicate that(Y_(0.75)Ca_(0.25))(Cu_(0.75)Mn_(0.25))SO is a direct bandgap semiconductor with a bandgap of 1.1 eV.The Fermi surface is asymmetric and exhibits spin splitting phenomenon.The new type of dilute magnetic semiconductor(Y_(0.75)Ca_(0.25))(Cu_(0.75)Mn_(0.25))SO exhibits significant light loss around 70 eV,with light reflection gradually increasing after 30 eV,and light absorption mainly occurring around 8-30 eV.These results also provide a basis for the discovery of more types of 1111 phase new dilute magnetic semiconductors in the future.展开更多
Expansive soil is sensitive to dry and wet environment change. And the volume deformation and inflation pressure of expansive soil may induce to cause the deformation failure of roadbed or many other adverse effects. ...Expansive soil is sensitive to dry and wet environment change. And the volume deformation and inflation pressure of expansive soil may induce to cause the deformation failure of roadbed or many other adverse effects. Aimed at a high-speed railway engineering practice in the newly built Yun-Gui high-speed railway expansive soil section in China, indoor vibration test on a full-scaled new cutting subgrade model is carried out. Based on the established track-subgrade-foundation of expansive soil system dynamic model test platform, dynamic behavior of new cutting subgrade structure under train loads coupling with extreme service environment(dry, raining, and groundwater level rising) is analyzed comparatively. The results show that the subgrade dynamic response is significantly influenced by service conditions and the dynamic response of subgrade gradually becomes stable with the increasing vibration times under various service environment conditions. The vertical dynamic soil stress is related with the depth in an approximate exponential function, and the curves of vertical dynamic soil stress present a "Z" shape distribution along transverse distance. The peak value of dynamic soil stress appears below the rail, and it increases more obviously near the roadbed surface. However, the peak value of dynamic soil stress is little affected outside 5.0 m of center line. The vibration velocity and acceleration are in a quadratic curve with an increase in depth, and the raining and groundwater level rising increase both the vibration velocity and the acceleration. The vertical deformations at different depths are differently affected by service environment in roadbed. The deformation of roadbed increases sharply when the water gets in the foundation of expansive soil, and more than 60% of the total deformation of roadbed occurs in expansive soil foundation. The laid waterproofing and drainage structure layer, which weakens the dynamic stress and improves the track regularity, presents a positive effect on the control deformation of roadbed surface. An improved empirical formula is then proposed to predict the dynamic stress of ballasted tracks subgrade of expansive soil.展开更多
The Chinese economy has achieved remarkable development over the past 40 years of reform and opening-up.However,with the narrowing of potential for efficiency improvement from resources reallocation and changes in pop...The Chinese economy has achieved remarkable development over the past 40 years of reform and opening-up.However,with the narrowing of potential for efficiency improvement from resources reallocation and changes in population age structure,the Chinese economy has moved from high-speed growth to high-quality development.In this setting,understanding factor endowment and comparative advantages of the economy from a perspective of human capital structure so as to enhance industrial structure adaptability by riding the trend is of significance for cultivating new driving force for economic development.This paper,following a theoretical paradigm of new structural economics,demonstrates how human capital structure matches industrial structure and the presence of optimal human capital structure using mathematical deduction.On this basis,national level panel data and instrumental variables are adopted for generalized method of moments,the results of which shows that there are varied impacts on economic growth in light of different human capital structure characteristics.The proportions of high-level human capital and medium-level human capital boost economic development,while that of low-level human capital has an inhibitory effect on economic growth.The policy implication of this study is that large economies should diversify efforts as per different human capital structure characteristics in terms of development need of tapping growth impetus from human capital structure improvement.It is of equal importance to raise the proportion of high and medium human capital in order to stimulate economic growth and to cut the proportion of low human capital that hinders economic development.展开更多
The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partialdifferential equation. Applying the Backlund transformation and introducing the arbitraryf...The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partialdifferential equation. Applying the Backlund transformation and introducing the arbitraryfunctions of the seed solutions, the abundance of the localized structures of this model are derived. Some special types ofsolutions solitoff, dromions, dromion lattice, breathers and instantons are discussed by selecting the arbitrary functionsappropriately. The breathers may breath in their amplititudes, shapes, distances among the peaks and even the numberof the peaks.展开更多
A new protoilludane sesquiterpenoid aromatic ester,named armillarizin (1)has been isolated from the artificially cultured mycelium of Armillaria me- llea(Vahl.ex Fr)Quel.(Tricholomataceae).Its structure was deduced on...A new protoilludane sesquiterpenoid aromatic ester,named armillarizin (1)has been isolated from the artificially cultured mycelium of Armillaria me- llea(Vahl.ex Fr)Quel.(Tricholomataceae).Its structure was deduced on the ba- sis of spectral analyses.The relative configuration was established from the nuclear Overhauser effects and from the values of ~1H-~1H coupling constants.展开更多
The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the residen...The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the resident immune cells and the frontline defenders responsible for the immune response of the brain. Resting microglia possess a ramified morphology with numerous thin processes that continuously sample the environment. In response to inflammatory signals, microglia become activated and transform their morphology into a thick, amoeboid-like shape. Activated microglia proliferate, tolerate to sites of iniurv,展开更多
A new compound Sr6Sn2Nb8O30 was found in the ternary system of SrO-SnO2-Nb2O5. The transparent colorless crystal with needle-like shape can be grown by flux method. The crystal structure of new compound was determined...A new compound Sr6Sn2Nb8O30 was found in the ternary system of SrO-SnO2-Nb2O5. The transparent colorless crystal with needle-like shape can be grown by flux method. The crystal structure of new compound was determined by X-ray diffraction, and its belongs to tungsten bronze structure. Sr6Sn2Nb8O30 crystallizes in orthorhombic system with unit cell parameters a= 17. 579 (DA,6= 17. 509(DA,c=7. 7880(5)A,Z = 4 and space group Cmm2.展开更多
A new prenylated flavonol, maackiaflavonol, was isolated from the ethanol extract of the roots of Maackia tenuifolia. Its structure was elucidated as 7-hydrox-8-prenylflavonol by means of spectroscopic analysis (UV, I...A new prenylated flavonol, maackiaflavonol, was isolated from the ethanol extract of the roots of Maackia tenuifolia. Its structure was elucidated as 7-hydrox-8-prenylflavonol by means of spectroscopic analysis (UV, IR, MS, NMR and 1H-1H COSY) and confirmed by total synthesis.展开更多
The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partial differential equation. Applying the B?cklund transformation and introducing the arbitrary...The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partial differential equation. Applying the B?cklund transformation and introducing the arbitrary functions of the seed solutions, the abundance of the localized structures of this model are derived. Some special types of solutions solitoff, dromions, dromion lattice, breathers and instantons are discussed by selecting the arbitrary functions appropriately. The breathers may breath in their amplititudes, shapes, distances among the peaks and even the number of the peaks.展开更多
Using ELES model and econometric methods,in the context of new urbanization,we use the time series data on the consumer spending of rural residents in Chongqing City to perform an empirical analysis of the consumer de...Using ELES model and econometric methods,in the context of new urbanization,we use the time series data on the consumer spending of rural residents in Chongqing City to perform an empirical analysis of the consumer demand structure of rural residents,reveal the characteristics,differences and changes concerning the consumption structure of rural residents in Chongqing City,and set forth some policy recommendations such as carrying out the new rural construction,optimizing the consumption structure,establishing sound social security system and income growth mechanism,and stabilizing the price level.展开更多
Early human embryonic development remains mysterious due to drastic species divergences between humans and othermammalian models and limited accessibility to human embryo samples. Recent studies from my laboratory and...Early human embryonic development remains mysterious due to drastic species divergences between humans and othermammalian models and limited accessibility to human embryo samples. Recent studies from my laboratory and others haveshown that under suitable culture conditions human pluripotent stem cells ( hPSCs) can undergo intricate morphogenetic eventsand self-organize to form patterned human embryo-like structures in vitro. These synthetic human embryonic tissueshold great promises for advancing human embryology and reproductive medicine. In this talk,I will describe a hPSC-based,synthetic 3D model of human post-implantation development that recapitulates key developmental landmarks successively,including pro-amniotic cavity formation,amniotic ectoderm-epiblast patterning,primordial germ cell specification,and developmentof the primitive streak with controlled anteroposterior polarity ( Fig.1) . We further show that the amniotic ectoderm,as the first lineage that segregates from the epiblast upon implantation of the human embryo,functions as a signaling centerto trigger primitive streak development in the epiblast. Together,our research has developed a powerful synthetic embryologicalmodel and provided new understandings of previously inaccessible but critical embryogenic events in human development.展开更多
The copper (II) complex (1) of a new Iigand 4- (quinolin-8-ylmethyl)- 1, 4, 7. 10-tetraazacycoltridecane-11. 13-dione (L) has been syntehsized and its crystal structure determined. It is of orthorhomic crystal system ...The copper (II) complex (1) of a new Iigand 4- (quinolin-8-ylmethyl)- 1, 4, 7. 10-tetraazacycoltridecane-11. 13-dione (L) has been syntehsized and its crystal structure determined. It is of orthorhomic crystal system and Pcad space group with a=16.260 (3), b=7. 739 (2). c=27. 530 (9) A, Mr=416. 97, Z=8. Dx=1. 595 g/cm3,μ=12. 876 cm-1, and F(000)=1736. The final R factor is 0. 061 for 2594 observed reflections with I>3σ(I). The Cu .atom is five coordinated to form a distorted square pyramid geometry in which N(11) of the pendant is at apical site.展开更多
A variable separation approach is proposed and extended to the (1+1)-dimensional physics system. The variable separation solution of (1-F1)-dimensional Ito system is obtained. Some special types of solutions such...A variable separation approach is proposed and extended to the (1+1)-dimensional physics system. The variable separation solution of (1-F1)-dimensional Ito system is obtained. Some special types of solutions such as non-propagating solitary wave solution, propagating solitary wave solution and looped soliton solution are found by selecting the arbitrary function appropriately.展开更多
The Papua New Guinea-Solomon(PN-SL)arc is one of the regions with active crustal motions and strong geological actions.Thus,its complex subduction system makes it an ideal laboratory for studying the initiation mechan...The Papua New Guinea-Solomon(PN-SL)arc is one of the regions with active crustal motions and strong geological actions.Thus,its complex subduction system makes it an ideal laboratory for studying the initiation mechanism of plate subduction.However,the PN-SL subduction system has not yet been sufficiently studied,and its density structure has yet to be revealed.In this paper,we used the free-air gravity data,Parker-Oldenburg density surface inversion method,and the genetic algorithm density inversion method to obtain the density structure of an approximately 1000-km-long northwest-southeast line crossing the PN-SL subduction system under the constraints of the CRUST1.0 global crustal model,onshore seismic data,and the LLNL-G3Dv3 global P-wave velocity model.The density structure shows that density differences between the plates on the two sides of the trench could play a significant role in plate subduction.展开更多
The described structural model tries to answer some open questions such as: Why do quarks not exist in the open state? Where are the antiparticles from the Big Bang?
New Schiff base Macrocyclic compound of 2,3: 11, 12:20, 21:29, 30-tetrabenzo-1,13,16,19,31,34-hexaoxa-5,6,8,9,23,24,26,27-octaaza-7,25-dithione-2,3:4,5:9,10:11,12:22, 23:27,28:29,30 cyclo-[36]ene (thione2B4[36] ene-O6...New Schiff base Macrocyclic compound of 2,3: 11, 12:20, 21:29, 30-tetrabenzo-1,13,16,19,31,34-hexaoxa-5,6,8,9,23,24,26,27-octaaza-7,25-dithione-2,3:4,5:9,10:11,12:22, 23:27,28:29,30 cyclo-[36]ene (thione2B4[36] ene-O6N8) containing THF has been prepared. It crystallizes in the monoclinic, space group P21/n. with parameters a=9.829(5) b=24.23(1), c=10.181(9), β=92.93(5)°, Z=2, V=2422(3)3, Dc=1.25gcm-3. Data collection: Rigaku AFC-5R diffractometer,(MoKα, λ=0.71069), ω /2θ scans. θmax=25°, empirical absorption correction, 4658 measured reflections, 4387 independent, 1743 observed reflections [I≥3σ(I)]. The final R=0.056. RW=0.069,S=1 .54, (Δ/σ)max=0.01,Δρmax=0.36e-3.展开更多
A lignan diol (1) was isolated from Schisandra rubriflora Rhed et Wils. It is racemic, with RS, RS, RS, SR configurations for the four consecutive asymmetric centers as shown.
Objective The Jilin-Liaoning area has widely spread Meso- and Neoproterozoic sediments and is always a focused area for researching Precambrian geology. Previous study has achieved a series of results about Neoprotero...Objective The Jilin-Liaoning area has widely spread Meso- and Neoproterozoic sediments and is always a focused area for researching Precambrian geology. Previous study has achieved a series of results about Neoproterozoic stratigraphy in this area, but the lack of precise geochronological data and signs of stratigraphic correlation has resulted in the long controversial stratigraphic age and regional correlation. During recent years,展开更多
文摘The aspect ratio of the structure has a significant impact on the overall stability of the ultra high-rise building. A large aspect ratio of the structure increases the risk of overturning and reduces the lateral stiffness of the structure, leading to significant tensile and compressive stresses in the isolated bearings. To study the effect of aspect ratio on the seismic response and overturning resistance of a new staggered story isolated structure, three models with different aspect ratios were established. Nonlinear time-history analysis of the three models was conducted using ETABS finite element software. The results indicate that the overturning moment and overturning resistance moment of the superstructure in the new staggered story isolated structure increase with an increasing aspect ratio. However, the increase in the overturning moment of the superstructure is much greater than the increase in the overturning resistance moment, resulting in a decrease in the overturning resistance ratio of the superstructure with an increasing aspect ratio. The overturning moment and overturning resistance moment of the substructure in the new staggered story isolated structure decrease with an increasing aspect ratio. However, the decrease in the overturning moment of the substructure is greater than the decrease in the overturning resistance moment, leading to an increase in the overturning resistance ratio of the substructure with an increasing aspect ratio. The decrease in the overturning resistance ratio of the superstructure in the new staggered story isolated structure is much greater than the increase in the overturning resistance ratio of the substructure. Therefore, as the aspect ratio of the overall structure increases, the overturning resistance ratio of the superstructure and the entire structure decreases.
文摘The band structure,DOSs,and optical properties of(Y_(0.75)Ca_(0.25))(Cu_(0.75)Mn_(0.25))SO,including dielectric function,absorption function,reflection function,and energy loss spectrum were studied by using the first-principles calculation.The calculation results indicate that(Y_(0.75)Ca_(0.25))(Cu_(0.75)Mn_(0.25))SO is a direct bandgap semiconductor with a bandgap of 1.1 eV.The Fermi surface is asymmetric and exhibits spin splitting phenomenon.The new type of dilute magnetic semiconductor(Y_(0.75)Ca_(0.25))(Cu_(0.75)Mn_(0.25))SO exhibits significant light loss around 70 eV,with light reflection gradually increasing after 30 eV,and light absorption mainly occurring around 8-30 eV.These results also provide a basis for the discovery of more types of 1111 phase new dilute magnetic semiconductors in the future.
基金Projects(51478484,51308551,51678571)supported by the National Natural Science Foundation of ChinaProject(2016zzts063)supported by Fundamental Research Funds for the Central Universities,China
文摘Expansive soil is sensitive to dry and wet environment change. And the volume deformation and inflation pressure of expansive soil may induce to cause the deformation failure of roadbed or many other adverse effects. Aimed at a high-speed railway engineering practice in the newly built Yun-Gui high-speed railway expansive soil section in China, indoor vibration test on a full-scaled new cutting subgrade model is carried out. Based on the established track-subgrade-foundation of expansive soil system dynamic model test platform, dynamic behavior of new cutting subgrade structure under train loads coupling with extreme service environment(dry, raining, and groundwater level rising) is analyzed comparatively. The results show that the subgrade dynamic response is significantly influenced by service conditions and the dynamic response of subgrade gradually becomes stable with the increasing vibration times under various service environment conditions. The vertical dynamic soil stress is related with the depth in an approximate exponential function, and the curves of vertical dynamic soil stress present a "Z" shape distribution along transverse distance. The peak value of dynamic soil stress appears below the rail, and it increases more obviously near the roadbed surface. However, the peak value of dynamic soil stress is little affected outside 5.0 m of center line. The vibration velocity and acceleration are in a quadratic curve with an increase in depth, and the raining and groundwater level rising increase both the vibration velocity and the acceleration. The vertical deformations at different depths are differently affected by service environment in roadbed. The deformation of roadbed increases sharply when the water gets in the foundation of expansive soil, and more than 60% of the total deformation of roadbed occurs in expansive soil foundation. The laid waterproofing and drainage structure layer, which weakens the dynamic stress and improves the track regularity, presents a positive effect on the control deformation of roadbed surface. An improved empirical formula is then proposed to predict the dynamic stress of ballasted tracks subgrade of expansive soil.
文摘The Chinese economy has achieved remarkable development over the past 40 years of reform and opening-up.However,with the narrowing of potential for efficiency improvement from resources reallocation and changes in population age structure,the Chinese economy has moved from high-speed growth to high-quality development.In this setting,understanding factor endowment and comparative advantages of the economy from a perspective of human capital structure so as to enhance industrial structure adaptability by riding the trend is of significance for cultivating new driving force for economic development.This paper,following a theoretical paradigm of new structural economics,demonstrates how human capital structure matches industrial structure and the presence of optimal human capital structure using mathematical deduction.On this basis,national level panel data and instrumental variables are adopted for generalized method of moments,the results of which shows that there are varied impacts on economic growth in light of different human capital structure characteristics.The proportions of high-level human capital and medium-level human capital boost economic development,while that of low-level human capital has an inhibitory effect on economic growth.The policy implication of this study is that large economies should diversify efforts as per different human capital structure characteristics in terms of development need of tapping growth impetus from human capital structure improvement.It is of equal importance to raise the proportion of high and medium human capital in order to stimulate economic growth and to cut the proportion of low human capital that hinders economic development.
基金The project supported by National Natural Science Foundation of China
文摘The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partialdifferential equation. Applying the Backlund transformation and introducing the arbitraryfunctions of the seed solutions, the abundance of the localized structures of this model are derived. Some special types ofsolutions solitoff, dromions, dromion lattice, breathers and instantons are discussed by selecting the arbitrary functionsappropriately. The breathers may breath in their amplititudes, shapes, distances among the peaks and even the numberof the peaks.
文摘A new protoilludane sesquiterpenoid aromatic ester,named armillarizin (1)has been isolated from the artificially cultured mycelium of Armillaria me- llea(Vahl.ex Fr)Quel.(Tricholomataceae).Its structure was deduced on the ba- sis of spectral analyses.The relative configuration was established from the nuclear Overhauser effects and from the values of ~1H-~1H coupling constants.
基金supported by the Bio&Medical Technology Development Program of the National Research Foundation of Korea(NRF)grant(No.2012M3A9C6049935)the DGIST Convergence Science Center Program(15-BD-04)of the Ministry of Science,ICT and Future Planning of Korea
文摘The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the resident immune cells and the frontline defenders responsible for the immune response of the brain. Resting microglia possess a ramified morphology with numerous thin processes that continuously sample the environment. In response to inflammatory signals, microglia become activated and transform their morphology into a thick, amoeboid-like shape. Activated microglia proliferate, tolerate to sites of iniurv,
基金Funded by International Centre for Diffraction Data(ICDD).
文摘A new compound Sr6Sn2Nb8O30 was found in the ternary system of SrO-SnO2-Nb2O5. The transparent colorless crystal with needle-like shape can be grown by flux method. The crystal structure of new compound was determined by X-ray diffraction, and its belongs to tungsten bronze structure. Sr6Sn2Nb8O30 crystallizes in orthorhombic system with unit cell parameters a= 17. 579 (DA,6= 17. 509(DA,c=7. 7880(5)A,Z = 4 and space group Cmm2.
文摘A new prenylated flavonol, maackiaflavonol, was isolated from the ethanol extract of the roots of Maackia tenuifolia. Its structure was elucidated as 7-hydrox-8-prenylflavonol by means of spectroscopic analysis (UV, IR, MS, NMR and 1H-1H COSY) and confirmed by total synthesis.
文摘The variable separation approach is used to obtain localized coherent structures of the new (2+1)-dimensional nonlinear partial differential equation. Applying the B?cklund transformation and introducing the arbitrary functions of the seed solutions, the abundance of the localized structures of this model are derived. Some special types of solutions solitoff, dromions, dromion lattice, breathers and instantons are discussed by selecting the arbitrary functions appropriately. The breathers may breath in their amplititudes, shapes, distances among the peaks and even the number of the peaks.
基金Supported by Key Research Project of the Ministry of EducationFundamental Research Funds for Central Universities
文摘Using ELES model and econometric methods,in the context of new urbanization,we use the time series data on the consumer spending of rural residents in Chongqing City to perform an empirical analysis of the consumer demand structure of rural residents,reveal the characteristics,differences and changes concerning the consumption structure of rural residents in Chongqing City,and set forth some policy recommendations such as carrying out the new rural construction,optimizing the consumption structure,establishing sound social security system and income growth mechanism,and stabilizing the price level.
基金supported by the National Science Foundation ( CMMI 1129611 and CBET 1149401)the National Institutes of Health ( R21 HL114011 and R21 EB017078)+3 种基金the American Heart Association ( 12SDG12180025)the Department of Mechanical Engineering at the University of Michigan,Ann ArborThe Lurie Nanofabrication Facility at the University of Michigan,a member of the National Nanotechnology Infrastructure Network ( NNIN)funded by the National Science Foundation,is acknowledged for support in microfabrication
文摘Early human embryonic development remains mysterious due to drastic species divergences between humans and othermammalian models and limited accessibility to human embryo samples. Recent studies from my laboratory and others haveshown that under suitable culture conditions human pluripotent stem cells ( hPSCs) can undergo intricate morphogenetic eventsand self-organize to form patterned human embryo-like structures in vitro. These synthetic human embryonic tissueshold great promises for advancing human embryology and reproductive medicine. In this talk,I will describe a hPSC-based,synthetic 3D model of human post-implantation development that recapitulates key developmental landmarks successively,including pro-amniotic cavity formation,amniotic ectoderm-epiblast patterning,primordial germ cell specification,and developmentof the primitive streak with controlled anteroposterior polarity ( Fig.1) . We further show that the amniotic ectoderm,as the first lineage that segregates from the epiblast upon implantation of the human embryo,functions as a signaling centerto trigger primitive streak development in the epiblast. Together,our research has developed a powerful synthetic embryologicalmodel and provided new understandings of previously inaccessible but critical embryogenic events in human development.
文摘The copper (II) complex (1) of a new Iigand 4- (quinolin-8-ylmethyl)- 1, 4, 7. 10-tetraazacycoltridecane-11. 13-dione (L) has been syntehsized and its crystal structure determined. It is of orthorhomic crystal system and Pcad space group with a=16.260 (3), b=7. 739 (2). c=27. 530 (9) A, Mr=416. 97, Z=8. Dx=1. 595 g/cm3,μ=12. 876 cm-1, and F(000)=1736. The final R factor is 0. 061 for 2594 observed reflections with I>3σ(I). The Cu .atom is five coordinated to form a distorted square pyramid geometry in which N(11) of the pendant is at apical site.
文摘A variable separation approach is proposed and extended to the (1+1)-dimensional physics system. The variable separation solution of (1-F1)-dimensional Ito system is obtained. Some special types of solutions such as non-propagating solitary wave solution, propagating solitary wave solution and looped soliton solution are found by selecting the arbitrary function appropriately.
基金the National Natural Science Foundation of China(Nos.91858215,42076224)。
文摘The Papua New Guinea-Solomon(PN-SL)arc is one of the regions with active crustal motions and strong geological actions.Thus,its complex subduction system makes it an ideal laboratory for studying the initiation mechanism of plate subduction.However,the PN-SL subduction system has not yet been sufficiently studied,and its density structure has yet to be revealed.In this paper,we used the free-air gravity data,Parker-Oldenburg density surface inversion method,and the genetic algorithm density inversion method to obtain the density structure of an approximately 1000-km-long northwest-southeast line crossing the PN-SL subduction system under the constraints of the CRUST1.0 global crustal model,onshore seismic data,and the LLNL-G3Dv3 global P-wave velocity model.The density structure shows that density differences between the plates on the two sides of the trench could play a significant role in plate subduction.
文摘The described structural model tries to answer some open questions such as: Why do quarks not exist in the open state? Where are the antiparticles from the Big Bang?
文摘New Schiff base Macrocyclic compound of 2,3: 11, 12:20, 21:29, 30-tetrabenzo-1,13,16,19,31,34-hexaoxa-5,6,8,9,23,24,26,27-octaaza-7,25-dithione-2,3:4,5:9,10:11,12:22, 23:27,28:29,30 cyclo-[36]ene (thione2B4[36] ene-O6N8) containing THF has been prepared. It crystallizes in the monoclinic, space group P21/n. with parameters a=9.829(5) b=24.23(1), c=10.181(9), β=92.93(5)°, Z=2, V=2422(3)3, Dc=1.25gcm-3. Data collection: Rigaku AFC-5R diffractometer,(MoKα, λ=0.71069), ω /2θ scans. θmax=25°, empirical absorption correction, 4658 measured reflections, 4387 independent, 1743 observed reflections [I≥3σ(I)]. The final R=0.056. RW=0.069,S=1 .54, (Δ/σ)max=0.01,Δρmax=0.36e-3.
文摘A lignan diol (1) was isolated from Schisandra rubriflora Rhed et Wils. It is racemic, with RS, RS, RS, SR configurations for the four consecutive asymmetric centers as shown.
基金supported by the Nature Science Foundation of China(grant No.41472082)China Geological Survey(grant No.121201102000150012)
文摘Objective The Jilin-Liaoning area has widely spread Meso- and Neoproterozoic sediments and is always a focused area for researching Precambrian geology. Previous study has achieved a series of results about Neoproterozoic stratigraphy in this area, but the lack of precise geochronological data and signs of stratigraphic correlation has resulted in the long controversial stratigraphic age and regional correlation. During recent years,