Seven new boronic acid adducts of technetium(III) tris(dioxime) (BATO) were prepared and the biodistribution in mice of Tc-99m labelled BATOs were determined. The uptake of 1.62%1D in mice heart at 2 min after injecti...Seven new boronic acid adducts of technetium(III) tris(dioxime) (BATO) were prepared and the biodistribution in mice of Tc-99m labelled BATOs were determined. The uptake of 1.62%1D in mice heart at 2 min after injection of (TcCl)-Tc-99m(MeCDO)(3)BMe indicates high myocardial extraction of this BATO. (TcCl)-Tc-99m(MeCDO)(3)BMe shows promise as a myocardial perfusion imaging agent.展开更多
文摘Seven new boronic acid adducts of technetium(III) tris(dioxime) (BATO) were prepared and the biodistribution in mice of Tc-99m labelled BATOs were determined. The uptake of 1.62%1D in mice heart at 2 min after injection of (TcCl)-Tc-99m(MeCDO)(3)BMe indicates high myocardial extraction of this BATO. (TcCl)-Tc-99m(MeCDO)(3)BMe shows promise as a myocardial perfusion imaging agent.
