Research Progress in the Treatment of New Bone Formation of Ankylosing Spondylitis

Ankylosing spondylitis(AS)has a very high disability rate.How to effectively inhibit the formation of new bones has become a difficult point in clinical treatment.In recent years,research has shown that different treatment plans can have an impact on inhibiting new bone formation.In this paper,the different effects of new bone formation in the treatment of AS with traditional Chinese and Western medicine are systematically listed.

Stressors in Nurse Students’ Formation in the New Normality Post COVID-19

Background: Mental health has been impaired and at risk due to the worldwide COVID-19 pandemic. The consequences due to confinement impacted every scenario, which directly influenced the daily routine of nurse students;in each setting students faced stressors that trigger fear, anxiety and others, since being in confinement learning of topics moved to the home, laboratory practices in hospitals were cancelled leaving the room that is uncertain up to their return to in-person activities. It is important to highlight the need for innovation and strengthening of theoretical-pedagogic aspects centered at the student’s context as a human being with their own needs and problems, who will interact with others in the continuous process of health-illness. Objective: the aim was to identify the stressors in the nurse students’ formation in the new normality post-COVID-19. Methods: Qualitative and phenomenological research with 27 participants aged 20 - 25 years, nurse students of a public university. The information collection was through four focal groups of 6-7 members each, data analysis was done according to Miles & Huberman after signed informed consent of each participant, and authorized by the chairperson of the Nurse’ career. Results: Category 1, Cumulative stressors with sub-categories 1.1 Uncertainty, 1.2 Isolation, 1.3 Invisibility, 1.4 Mockery, 1.5 Exclusion. Category 2, Expectancy states with sub-categories 2.1 Low self-esteem, 2.2 Insecurity, 2.3 Anxiety, 2.4 Depression, 2.5 Temporary leave, 2.6 Search for authenticity. Category 3, Internalization processes with sub-categories 3.1 Social rejection, 3.2 Self-censorship, 3.3 Discrediting, 3.4 Disempowerment. Category 4, Academic aspects affected with sub-categories 4.1 Deficient studying habits, 4.2 Deficient assimilations of knowledge, 4.3 Archived knowledge in the computer, 4.4 Absence of practice in previous semesters. Conclusion: Once identified the stressors in nurse students in the new normality post-COVID-19, it will allow the creation of settings that help in getting confidence for students, i.e., a safe surrounding promotes the development of abilities and competencies during formation, as well as recommendations of teachers in the classroom and laboratories that contribute to filling space that students perceive as empty, and to intensifying the companionship in clinical settings where students perceive most aggressiveness.

A Glance on the Mineral Deposits and Stratigraphic Sequential Variations and Structures in Different Sections of Indus Basin (Pakistan): New Titanosaurian Sauropod Dinosaurs from the Latest Maastrichtian Vitakri Formation of Pakistan

Indus basin hosts many significant mineral deposits like gypsum and cement raw materials, gemstones, iron, coal, marble, dimension and construction stones, petroleum and water resources, world class pink salt and other many minerals in different regions which need further exploitation and development. The construction of new water dams in different regions are vital (for availability of cheap electricity), because of available barren and fertile lands and wastage of water as flood. Further the installation of more cement industries in different regions of Indus Basin especially in middle Indus (Sulaiman Range where gypsum, clays and limestones can be available via belt) can increase export to receive more foreign exchange and make local cement cheap for the sustainable development of Pakistan. 31 stratigraphic sequential sections at different sections of Indus basins are presented to know the variation and local stratigraphy. Further here three new titanosaur taxa are being described. Saraikimasoom is based on snout;Gspsaurus, (Maojandino), Nicksaurus and Khanazeem are based on cranial, vertebral and appendicular elements;Balochisaurus, Marisaurus, Pakisaurus, and 3 new genera and species Imrankhanhero zilefatmi, Qaikshaheen masoomniazi and Ikqaumishan smqureshi based on vertebral and appendicular elements;and Sulaimanisaurus and Khetranisaurus based on only caudal vertebrae. Although Pakistani Titanosaurians seem to be proliferated found from one horizon of Vitakri Formation just below the K-Pg boundary they have a wide range of diagnostic features and key elements among titanosaurs which can be used for comparison and phylogenetic analyses with broad updated character data set of titanosaurs.

Aerosol Spectra and New Particle Formation Observed in Various Seasons in Nanjing

The aerosol number spectrum and gas pollutants were measured and the new particle formation （NPF） events were discussed in Nanjing. The results showed that the size distributions of aerosol number concen- trations exhibited distinct seasonal variations, implying the relations of particle sizes and their sources and sinks. The number concentrations of particles in the nuclei mode （10-30 nm）, Aitken mode （30-100 nm）, accumulation mode （100 -1000 nm） and coarse mode （〉1μm） varied in the order of summer 〉 spring 〉 autumn, summer 〉 autumn 〉 spring, autumn 〉 summer 〉 spring, and spring 〉 autumn 〉summer, re- spectively. The diurnal variation of total aerosol number concentrations showed three peaks in all observed periods, which corresponded to two rush hours and the photochemistry period at noon. In general, the NPF in summer occurred under the conditions of east winds and dominant air masses originating from marine areas with high relative humidity （50%-70%） and strong solar radiations （400 -700 W m-2）. In spring, the NPF were generally accompanied by low relative humidity （14%-30%） and strong solar radiations （400-600 W m-2）. The new particle growth rates （GR） were higher in the summertime in the range of 10- 16 nm h-1. In spring, the GR were 6.8-8.3 nm h-1. Under polluted air conditions, NPF events were seldom captured in autumn in Nanjing. During NPF periods, positive correlations between 10- 30 nm particles and 03 were detected, particularly in spring, indicating that NPF can be attributed to photochemical reactions.

New Fossil Xyelidae(Insecta,Hymenoptera) from the Yixian Formation of Western Liaoning,China

In this paper one new genus and two new species,Brachyoxyela brevinodia sp.nov.and Brachyoxyela gracilenta sp.nov.,in the subfamily Macroxyehnae of the family Xyelidae,are described and illustrated.The specimens were collected from the Yixian Formation,the Upper Jurassic to Lower Cretaceous,of Beipiao City,Liaoning Province,northeastern China.The new genus is established based on the characters that vein Sc meets R only beyond origin of Rs,third antennal segment is almost equal in length to the rest flagellomeres combined,terminal flagellomeres increasingly shortened toward apex,and vein 2r-rs inclined toward the apex of wing.

New Pelecinid Wasps (Hymenoptera:Proctotrupoidea:Pelecinidae) from the Yixian Formation of Western Liaoning,China

Three well-preserved fossil Pelecinids from the Late Mesozoic Yixian Formation,Liaoning Province,China are described and assigned to two new species,Eopelecinus huangi sp.nov.and Eopelecinus tumidus sp.nov.in Eopelecinus Zhang,Rasnitsyn and Zhang,2002.As of now,17 species have been included in this genus,which is the most diverse in the Pelecinidae family.With new information and characters obtained from these new specimens,the diagnosis of Eopelecinus Zhang, Rasnitsyn and Zhang,2002 is emended.

New U-Pb Geochronological Constraints on Formation and Evolution of the Susong Complex Zone in the Dabie Orogen

Objective The Susong complex zone（SCZ）is a relatively lowgrade metamorphic unit mostly with an epidoteamphibolite facies,located in the southernmost part of the Dabie orogen.However,its rock compositions,ages,

MEASUREMENTS OF PARTICLE NUMBER SIZE DISTRIBUTIONS AND NEW PARTICLE FORMATION EVENTS DURING WINTER IN THE PEARL RIVER DELTA REGION,CHINA

Particle number size distribution(PNSD) between 10 nm and 20 μm were measured in the Pearl River Delta(PRD) region in winter 2011.The average particle number concentration of the nucleation mode(10-20 nm),Aitken mode(20-100 nm),accumulation mode(100 nm-1μm) and coarse mode(1-20 μm) particles were 1 552,7 470,4 012,and 19 cm-3,respectively.The volume concentration of accumulation mode particles with peak at 300 nm accounted for over 70% of the total volume concentration.Diurnal variations and dependencies on meteorological parameters of PNSD were investigated.The diurnal variation of nucleation mode particles was mainly influenced by new particle formation events,while the diurnal variation of Aitken mode particles correlated to the traffic emission and the growth process of nucleation mode particles.When the PRD region was controlled by a cold high pressure,conditions of low relative humidity,high wind speed and strong radiation are favorable for the occurrence of new particle formation(NPF) events.The frequency of occurrence of NPF events was 21.3% during the whole measurement period.Parameters describing NPF events,including growth rate(GR) and source rate of condensable vapor(Q),were slightly larger than those in previous literature.This suggests that intense photochemical and biological activities may be the source of condensable vapor for particle growth,even during winter in the PRD.

New Discovery of Molar Tooth Structures in the Kangjia Formation at Benxi,Liaoning and its Significance

Objective The Jilin-Liaoning area has widely spread Meso- and Neoproterozoic sediments and is always a focused area for researching Precambrian geology. Previous study has achieved a series of results about Neoproterozoic stratigraphy in this area, but the lack of precise geochronological data and signs of stratigraphic correlation has resulted in the long controversial stratigraphic age and regional correlation. During recent years,

New Insights into the Depositional Environments of Ordovician Carbonate Formations in the Yubei Area of Tarim Basin Based on Standard Microfacies Types

Objective The Yubei area is located in the mid-east Maigaiti slope of southwestern Tarim Basin, China, with an exploration history of several years. Recent exploration has preliminarily indicated that the Ordovician carbonate formations in this area have some oil and gas potential. Carbonate microfacies provides material basis for reservoir development, seal formation and hydrocarbon generation. Therefore, this work utilized the standard microfacies （SMF） types to study the microfacies of the Ordovician formations in the Yubei area in order to provide theoretical basis for the next exploration.

New simulation model for bone formation markers in osteoporosis patients treated with once-weekly teriparatide

Daily 20-mg and once-weekly 56.5-mg teriparatide（parathyroid hormone 1–34） treatment regimens increase bone mineral density（BMD） and prevent fractures, but changes in bone turnover markers differ between the two regimens. The aim of the present study was to explain changes in bone turnover markers using once-weekly teriparatide with a simulation model. Temporary increases in bone formation markers and subsequent decreases were observed during once-weekly teriparatide treatment for 72 weeks. These observations support the hypothesis that repeated weekly teriparatide administration stimulates bone remodeling, replacing old bone with new bone and leading to a reduction in the active remodeling surface. A simulation model was developed based on the iterative remodeling cycle that occurs on residual old bone. An increase in bone formation and a subsequent decrease were observed in the preliminary simulation. For each fitted time point, the predicted value was compared to the absolute values of the bone formation and resorption markers and lumbar BMD. The simulation model strongly matched actual changes in bone turnover markers and BMD. This simulation model indicates increased bone formation marker levels in the early stage and a subsequent decrease. It is therefore concluded that remodeling-based bone formation persisted during the entire treatment period with once-weekly teriparatide.

Analysis of geological conditions and thermal reservoir characteristics of Guantao Formation in new coastal region

Geothermal resources is one of the most practical and competitive new energy at present,and there is abundant geothermal resources in the new coastal region.The article get the three following conclusion through the geothermal geological condition by the drilling strata and the condition of the reducing test:stratigraphic division is done by the analysis of formation lithology and the drilling aging;the water yield is higher than 100m3/h,the flow temperature is 67℃--71℃;the average geothermal gradient of the overlying strata is 3.08℃--3.33℃/100 m.

A New Understanding of the Lower Cretaceous Jiufotang Formation in Western Liaoning

The Lower Cretaceous Jiufotang Formation in western Liaoning is the most important fossil production horizon of the Jehol Biota, which is widely distributed in the Mesozoic basins of western Liaoning. Due to the influence of historical data, previous scholars believed that there was no volcanic activity in the Jiufotang Formation in western Liaoning. In a field investigation in western Liaoning, the authors discovered basalt and andesite in the Hujiayingzi bed. In addition, a conformable boundary was found between the Yixian and the Jiufotang formations. It indicates that both the Jiufotang Formation and the Yixian Formation are strata containing volcanic-sedimentary rocks, only differing in strength of volcanic activity.

New Zircon SHRIMP U-Pb Ages of the Langjiu Formation Volcanic Rocks in the Shiquanhe Area,Western Lhasa Terrane and their Implications

Objective The potassic and ultrapotassic rocks relating to the India-Eurasia collision and continual plate convergence are widely distributed in the Lhasa terrane. These rocks are very important to understand the deep processes of the India-Eurasia collision and the uplift and evolution of the Tibetan Plateau. Although high-potassic volcanic rocks are also exposed in the western Lhasa terrane, their formation time is still uncertain for the lack of reliable dating. We carried out zircon U-Pb geochronological study on the Langjiu Formation volcanic rocks, which are part of the Early Cretaceous Zenong group volcanic rocks based on 1：250000 scale Shiquanhe regional geological survey report, in the Shiquanhe area of the western Lhasa terrane. These new age data not only offer chronological basis for the regional stratigraphic correlation and classification, but also provide an essential opportunity for revealing signatures of magmatic pulses hidden in the deep crust of the Lhasa terrane.

Globalization Under the Spells of Breakdowns in Supply Chains, Regime Change, Regime Formation, and Alliance Restructuring: How Much Is Left for Public Goods?

In a paper conceived about five years ago(“Globalization and Public Goods:Too Big to Tackle?”)roughly a dozen factors were linked to explain important causal paths from globalization to the potential output of public goods.The Russian invasion of Ukraine,the corona epidemic,and the increased hegemonic rivalry between China and the U.S.interrupted or even destroyed many of the linkages between globalization and potential public good production.About five important detrimental paths involved in the meantime.In the present article we aim at linking what is left from the previous level of globalization or emerging to form a new and simplified causal model for likely linkages between truncated or(re-)emerging globalization,and the deadly needed output of public goods.These linkages refer to rules of climate control,go to trade linkages and arbitrary tariffs and trade interventions.Regime change,regime formation,and alliance restructuring address aspects of domestic rule and international stability.Selectorate theory,regime type,and exit options for political elites provide key explanatory factors in explaining globalization and public goods productions,or their decay.Where possible we use some data and transformation experiences corroborating our arguments.In other instances need for further empirical macro research will become clear.

A Cognitive Study of Word-formation of Chinese New Metaphorical Compounds

A great deal of new words are emerging and coming into vogue.Most of the previous studies on Chinese new words focused on their classification,form and meaning,as well as the social motivations.This thesis chooses to study the concept metaphor of Chinese new metaphorical compounds from the cognitive perspective based on 396 new words in 2010 and aims to classify the new metaphorical words in a new way and pay attention to the analysis of word formation of new metaphorical compounds.Besides,this paper attempts to explore the understanding process of metaphorical new words.

政治经济学视域下数字新质生产力的形成逻辑与内涵研究

数字技术快速发展,各行业数字化转型不断深化,数字新质生产力正在成为推动经济增长和社会进步的关键力量。为了全面解析数字新质生产力的形成逻辑和丰富内涵,进而推动其发展,本文采用文献分析、理论分析与数理推导的方法,基于马克思主义政治经济学的生产力理论,探讨了社会生产力的历史演进及其发展趋势,深入解读了数字新质生产力的本质及内涵、外延,重点分析其形成逻辑和作用特征。研究结果表明,数字新质生产力的本质是由前沿数字技术创新驱动的,更具包容性、更体现新内涵的先进生产力。数字新质生产力的基本内涵包括劳动者、劳动资料、劳动对象及其优化组合的跃升,外延涉及全要素生产率的提升和产业结构的优化两个核心方面。数字技术革命性突破、生产要素创新性配置以及产业深度转型升级三者的联合作用推动了数字新质生产力的形成,其作用特征表现为高科技、高效能和高质量。文章进一步阐释了数字新质生产力的构成,即以数字技术、数据要素、数字产业化与产业数字化为核心的动力机制与劳动者、劳动资料、劳动对象等生产要素相互渗透,进而提出了数字新质生产力的计算公式,用于评估其影响力。研究表明,数字新质生产力的出现既是对传统马克思主义生产力理论的继承,也是其创新发展,是社会生产力发展进入新阶段的具象表现之一,对数字新质生产力的深入研究,为理解并推动数字经济时代的高质量发展提供了重要视角。

数字文化新业态发展影响因素研究——基于DEMATEL-ISM-MICMAC展开的实证分析

文化与数字信息技术的相互融合孕育出了丰富多样的数字文化新业态,为我国文化产业发展注入了新的活力。发展数字文化新业态是文化产业升级的内在要求,客观科学地认识数字文化新业态发展的影响因素及其相互关系,有助于全方位解析数字文化新业态的发展机制和创新发展路径,以促进文化产业数字化战略的实施。通过识别15个数字文化新业态发展影响因素,运用DEMATEL法分析数字文化新业态发展各影响因素的重要程度,采用ISM-MICMAC法分析影响因素的层级关系与驱动-依赖关系,找出数字文化新业态发展的直接影响因素、间接影响因素和根本影响因素。研究表明:数字文化新业态发展以企业规模、服务创新、产品开发、人才培养、装备制造与模式创新为直接影响,以平台构建、数字化管理、资金支持与IP影响力为间接影响,以标准应用、资产禀赋、产学研协同、技术研发与政策支持为根本影响。

天津滨海地热田北部深部地热资源赋存规律

【研究目的】天津地热资源丰富,目前已开发的深部地热资源大部分位于“隆中凸”构造区域,而位于“坳中凸”构造区域的地热资源勘查和研究程度基本尚属空白,揭示其深部地热赋存规律可为滨海新区及京津冀地区寻找深部地热资源及勘探与开发提供重要参考。【研究方法】本文以黄骅坳陷宁河凸起中的桥沽地区为研究区,以近期新发现的资源禀赋最好的蓟县系雾迷山组热储层为研究对象,通过分析区域地质资料、大地电磁测深(MT)、钻孔测温和物探测井等资料,系统总结了研究区地质构造、地温场和深部地热资源赋存特征。【研究结果】雾迷山组储层的热储温度高(90~120℃),出水量大于100 m^(3)/h,埋藏相对较浅(2200~2800 m)。区内地质构造条件复杂,断裂构造发育,汉沽断裂为研究区重要的导热、导水通道;地温场呈现“两高夹一低”展布特征与两处背斜构造空间位置相对应;热源以壳源热为主、幔源热次之,大气降水为主要热水来源,热传输机制以热传导型为主。【结论】综合研究区深部地热赋存规律,建立了深部地热资源概念模型,明确了“坳中凸”深部地热找矿新思路。