New perspectives for investigating respiratory failure induced by cervical spinal cord injury

Traumatic cervical spinal cord injury （SCI）, with an annual incidence of 12,000 new cases in USA （NSCISC 2013）, causes devastating locomotor and respiratory paralysis and unfortunately compromises the human patient＇s lifespan. The severity of the injury depends on the degree and the extent of the initial trauma. In fact, respiratory failure is the leading cause of mortality following upper cervical SCI. However, 80% of the injuries are incomplete, allowing some modest spontaneous recovery. To date, no effective treatment is available in order to restore the loss of function.

The Early Modern Economy of the Yangzi Delta in a New Perspective

China has experienced spectacular economic growth during the past three decades and seen some parts of the country, in particular the Yangzi Delta, swiftly converging with the developed countries in the level of economic development. This unprecedented growth has been seen as the greatest economic miracle in world history. This miracle is based on the economic performance of the Yangzi Delta in the long run of centuries. It is impossible to achieve a better understanding of the economic miracle of the delta without a better understanding of the basis created by the delta＇s economy during its long historical development, in particular in the centuries before the modern West arrived in the mid- nineteenth century. To achieve this objective, we must break free of the West-centric straightjacket and study China＇s early modern economy from a new perspective, which will be crucial to improve our knowledge of Chinese economic performance prior to the arrival of the West.

Glyco-sphingo biology: a novel perspective for potential new treatments in Huntington's disease

Huntington＇s disease （HD） is the most common dominantly inherited neurodegenerative disorder, mainly characterized by the progressive striatal and cortical neurodegeneration and as- sociated motor, cognitive and behavioural disturbances （Zuccato et al., 2010）. The disease-causing mutation is an expansion of a GAG trinucleotide repeat （〉 36 repeats） encoding a polygluta- mine stretch in the N-terminal region ofhuntingtin （Htt） （Zuc- cato et al., 2010）, a ubiquitous protein whose function is still unclear （Zuccato et al., 2010）. Expansion of the polyQ stretch endows mutant Htt （mHtt） with toxic properties, and results in the development of a broad array of undesirable effects in both neuronal and non-neuronal cells （Zuccato et al., 2010）. Among all cellular dysfunctions and biochemical imbalances classically associated with HD, perturbed metabolism of （glyco） sphingolipids appears to play a crucial role in the pathogenesis of the disease. Over the last years, we and other have extensively contributed to these findings （Desplats et al., 2007;

China and Europe: Opening New Cooperation Perspectives

Economic and trade relations, as the cornerstone of China-Europe relations, are under- going structural changes. For most European countries, the promotion of China-Europe relations has gone beyond the divergence between the parties and become the po]itJcal consensus of all countries.

New FP/MCH Perspectives in China:A Study Tour

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Strategies for the Development of Economic Management in Universities Under the Perspective of New Media

Strategies for the development of university economic management under the new media perspective have been a critical concern for the higher education industry in China,and therefore,this paper will provide a detailed discussion on the development strategies of university economic management under the perspective of new media,and is expected to give researchers in the field of the necessary reference information.

Perspectives on Nutrition Needs for the New Millennium for South Asian Regions

South Asia is the most populated region of the world with several nutritional challenges. Though per capita food energy supply, child survival and life expectancy have improved, and even today large segments of the population are below the poverty line with high infant and maternal mortality rates. It is important to recognize the crucial role of nutrition throughout the life cycle from conception to old age. It is very necessary now to move from food security to nutrition security and improve the quality of foods both in macro and micronutrients in order to break the transgenerational effects of malnutrition. The key solutions to the problems should address the issue of social development, population stabilization, environmental degradation and inadequate health and nutritional services. Strategies for empowering women and actuating community participation as sustainable programmes for human development, measures to reduce underweight and stunting in children and prevention of micronutrient malnutrition across the population are required. Enhancing food and nutrition security through innovative diversified agriculture and dietary practices, prevention and control of infection, promotion of food safety and fortification of staples with appropriate attention on emerging chronic disorders are essential. Population control measures to stabilize the fertility rates, biotechnological approaches for genetically modified foods, nutrition surveillance based on assessment, analysis and action to address the logistic, technical and compliance issues with emphasis on promotion of breast feeding and complementary foods with adequate attention on the reproductive needs of adolescent girls, pregnant mothers and lactating women would eliminate low birth weight, stunting, and chronic energy deficiency in vulnerable groups. Focused studies on bioavailability of micronutrients and its enhancement, innovative horticulture interventions, fortifications, social marketing strategies would promote the intake of micronutrient and phytonutrient rich foods. In depth epidemiological research, an insight into foetal origins of adult disease and nutrition genes interaction and life style alterations will avert the emerging epidemic of chronic diet related disorders. An investment in preventing foetal malnutrition improves nutrition of women in reproductive age, infant and child nutrition and prevents the onset of chronic disease in adult life. Human resource development, IEC measures, technology transfer, operational and logistic research, building of databases, integrated, intersectoral, multidisciplinary plans and sound management information system and surveillance with net working and experience sharing in the region will help to overcome the common challenges and lay the foundation for a better scenario in these regions in the near future.

Perspectives on a New Life

WHAT does life mean? According to the traditional Chinese mentality, it means to clothe, feed and shelter oneself, and to be mobile. Today, these staples still apply, alongside an additional two: entertainment and education. The acquisition of two more essentials within a definition of the meaning of life indicates, from another perspective,

Reconstruction of a pre-Rodinia supercontinent: New advances and perspectives

The global collisional orogenic events (e.g. Grenvil-lian or Pan-African event) have occurred for several times since 2.5 billion years (Ga) ago, which has led Earth scientists to speculate that continental landmasses have periodically assembled and dispersed, resulting in the assembly and breakup of supercontinent. In the last decade, the reconstruction of ancient supercontinents has been focused on Rodinia, a defined supercontinent that was assembled along the -1.0 Ga "Grenvillian" oro-gens. In reconstructing Rodinia, however, Earth scientists have noticed that not all continental blocks in the supercontinent were welded by the -1.0 Ga orogenic belts (fig. 1(a)), and that most blocks welded by the 1.0 Ga orogens contain abundant evidence that they are a

Green Technology Innovation under China's New Development Concept:The Effects of Policy-Push and Demand-Pull on Renewable Energy Innovation

Green technology innovation meets the dual expectation of innovative development and green development perspectives.Under the canonical demand-pull and policy-push theories,a long-term mechanism for green technology innovation could be formed through upstream policy push and downstream demand-pull.Leveraging China's regional carbon emission trading scheme pilots as a quasi-natural experiment,this paper examines the policy-push and demand-pull effects on innovation in renewable energy patents.The data pertain to the city-level renewable energy patents from 2000 to 2020.Based upon the triple difference-in-difference method,results suggest that both policy-push and demandpull factors exert positive effects on innovation.This paper further explores the practical and theoretical implications of green technology innovation under the new development perspective.

TOWARDS A GLOBAL UNDERSTANDING OF THE HUMANE TREATMENT OF CAPTURED ENEMY FIGHTERS

The prevailing narrative instructs us that humane treatment of captured enemy fighters is down to white knights from the western parts of the European continent with their codes of chivalry, or alternatively, the Swiss businessman Henri Dunant. This contribution challenges that narrative for overlooking, or being ignorant of, the way that societies around the world have approached the matter of the captured enemy fighter. Traces of some of the critical principles about humane treatment that we see in our present law can actually be found in much older societies from outside of Europe. A more accurate and representative way of understanding humanitarianism in the treatment of captured enemy fighters can and must be crafted, with the prevailing Euro-centric account balanced with practices, cultures and faiths from elsewhere. The quest to achieve more humane treatment in armed conflict is first and foremost a battle of the intellect. Narratives and conceptualisations that are more inclusive, recognising and appreciating of the ways of the rest of the world are likely to be more effective in communicating humanitarian ideals. This work adopts a new method of approaching the richness and diversity of the treatment of captured enemy fighters over time and space. This new framework of analysis uses six cross-cutting themes to facilitate a broader international and comparative perspective, and develop a more sophisticated level of understanding. The first theme is how older and indigenous societies approached the matter of captured enemy fighters. The second focuses on religions of the world, and what they teach or require. The third section examines the matter of martial practices and codes of ethics for combatants in certain societies. The fourth category engages with colonisation and decolonisation, and regulation （or non-regulation） of the treatment of captives of war. Fifth is the issue of modernisation and the impact it has had on armed forces and fighters, including on the treatment of captives. The final issue is the shift towards formalised agreements, beginning with the first bilateral agreements and then the multilateral codification exercise that began in the mid-19th century and continues to this day. This framework for analysis leads into a final chapter, presenting a fresh and holistic view on the evolution of prisoner of war protections in the international order. It provides a different way of looking at International Humanitarian Law, starting with this effort at a global understanding of the treatment of captured enemy fighters.

RESEARCH ON NEGOTIATED TEACHING AND LEARNING IN CLASSROOM DECISION MAKING

This paper deals with the hypothesized problems or difficulties in the practice of negotiated teaching and learning in classroom decision-making, and with the solutions to them. Negotiation in teaching and learning has great elicitation of the reform of college English teaching, which involves the joint participation in classroom-decision-making, new teaching perspectives, and new designs of teaching modes.