Vulvodynia is a prevalent form of chronic pain, most com- monly affecting the vaginal vestibule (vestibulodynia) (Pukall et al., 2016). Women with vulvodynia describe intense pain in response to light touch of the...Vulvodynia is a prevalent form of chronic pain, most com- monly affecting the vaginal vestibule (vestibulodynia) (Pukall et al., 2016). Women with vulvodynia describe intense pain in response to light touch of the affected region, such that sexual function and other activities can be severely limited. Medical costs associated with vulvodynia are high, exceeding $21 billion annually in the United States (Xie et al., 2012). The high level of direct medical costs has been linked to high treatment failure rates. Many women with the disorder consult multiple practitioners and undergo multiple courses of treatment with limited benefit.展开更多
基金A project described in this work regarding innervation changes in the murine vagina in response to inflammation was supported by a grant from the Centre for Neuroscience,Flinders University,Australia
文摘Vulvodynia is a prevalent form of chronic pain, most com- monly affecting the vaginal vestibule (vestibulodynia) (Pukall et al., 2016). Women with vulvodynia describe intense pain in response to light touch of the affected region, such that sexual function and other activities can be severely limited. Medical costs associated with vulvodynia are high, exceeding $21 billion annually in the United States (Xie et al., 2012). The high level of direct medical costs has been linked to high treatment failure rates. Many women with the disorder consult multiple practitioners and undergo multiple courses of treatment with limited benefit.