The prescription rule analysis of the New Theory on Spleen Dampness Syndrome by Academician TONG Xiaolin

Objective To analyze the basic characteristics,drug features,prescription rules,and drug-symptom relationships of patients in the splenic deficiency and impairment stage,by data mining of medical records under the New Theory on Spleen Dampness Syndrome(Pi Dan Xin Lun,《脾瘅新论》).Methods Medical records listed in the“New Theory on Spleen Dampness Syndrome-Under-standing and Treatment of Metabolic Syndrome from the Perspective of Traditional Chinese Medicine”,and which were diagnosed with the spleen dampness syndrome at the splenic de-ficiency and impairment stage,during January 2004 and December 2016 were selected.These patients’data,including basic information,clinical symptoms,laboratory examination res-ults,traditional Chinese medicine(TCM)and western medicine diagnoses,treatment meth-ods,prescriptions,etc.,were collected.The collected data were subsequently compiled into a medical record database using the Epidata 3.1 data management software,followed by the use of Apriori algorithm provided in the SPSS Modeler 14.2 statistical software to investigate the association rules between drug-drug,drug-symptom,and drug-western medicine indices.Results(i)A total of 51 medical records were included,involving 17 types of syndromes.Among them,the top three with frequency≥3 included“Phlegm and blood stasis,and thoracic obstruction”“Deficiency-weakness of the spleen Qi,and static blood blocking collat-erals”,and“Deficiency-weakness of the spleen Qi,and static blood blocking collaterals”.Al-ternatively,of the 14 treatment methods,the top three treatments with frequency of≥3 in-cluded“Activating Yang and eliminating turbidity,and removing phlegm and dredging chan-nel blockage”“Strengthening the spleen and benefiting Qi,and eliminating phlegm to activ-ate the channels”,and“Warming Yang and benefiting Qi,and expelling cold to remove ob-structions”.Among the 15 prescriptions,the top three used with frequency≥3 included Huangqi Guizhi Wuwu Tang(黄芪桂枝五物汤),Gualou Xiebai Banxia Tang(瓜蒌薤白半夏汤),and Ganjiang Huangqin Huanglian Renshen Tang(干姜黄芩黄连人参汤).Lastly,of the 83 drugs used for a total of 476 times,those with frequency≥15 included Huanglian(Coptid-is Rhizoma),Huangqi(Astragali Radix),Jiudahuang(Wine-processed Rhei Radix et Rhizoma),Jixueteng(Spatholobi Caulis),Shengjiang(Zingiberis Rhizoma Recens),Huangqin(Scutellariae Radix),and Guizhi(Cinnamomi Ramulus).(ii)For the drug-drug associations,under the criteria of support≥15%and confidence=100%,seven second-order association rules,seven third-order rules,and six fourth-order roles were identified.The top-ranking rule of each was“Huangqin(Scutellariae Radix)→Huanglian(Coptidis Rhizoma)”“Ganjiang(Zingiberis Rhizoma)+Huangqin(Scutellariae Radix)→Huanglian(Coptidis Rhizoma)”,and“Baishao(Paeoniae Radix Alba)+Guizhi(Cinnamomi Ramulus)+Jixueteng(Spatho-lobi Caulis)→Huangqin(Scutellariae Radix)”,respectively.Alternatively,the drug-symptom associations were analyzed under the criteria of support≥5%and confidence=100%,which derived eight second-order association rules,31 third-order rules,and 30 fourth-order rules.The top-ranking association rule of each order was“Huangqi(Astragali Radix)→Limb ed-ema”“Guizhi(Cinnamomi Ramulus)+Jixueteng(Spatholobi Caulis)→Limb numbness and pain”,and“Guizhi(Cinnamomi Ramulus)+Jixueteng(Spatholobi Caulis)+Huangqi(As-tragali Radix)→Limb numbness and pain”,respectively.Similarly,the drug-western medi-cine index associations were investigated under the criteria of support≥5%and confidence=100%,and five second-order association rules,16 third-order rules,and 16 fourth-order rules were identified.In this category,the top-ranking association rule of each order was“Qinpi(Fraxini Cortex)→Uric acid”“Huanglian(Coptidis Rhizoma)+Ganjiang(Zingiberis Rhizoma)→Glycated hemoglobin”,and“Huanglian(Coptidis Rhizoma)+Ganjiang(Zing-iberis Rhizoma)+Huangqin(Scutellariae Radix)→Glycated hemoglobin”,respectively.Conclusion Through association rule mining,this study objectively and quantitatively demonstrated the drug-drug,drug-symptom,and drug-physicochemical index associations of patients with the spleen dampness syndrome at the splenic deficiency and impairment stage treated by Academician TONG Xiaolin.The results indicated that treatment for these patients adopted the“state-target”syndrome differentiation method.The drug combination was characterized by“small prescriptions”,targeting both the patient’s symptoms and signs(syndrome target)and western medicine indices(treatment target).This study could provide references for future research on the academic thoughts and medical experience of Academi-cian TONG Xiaolin.

Origin of Petroleum: A New Theory of Its Formation

Petroleum is not a production of direct transformation of organic material into kerogen or oil. Sea organics can’t form such huge oil fields, since these sea creatures will either be consumed by bigger ones or decayed after few days. Farther more these sea animals consist of several components, such as proteins, scales, bones, and minerals, which could not be changed into oil. These should be seen as oil contamination, and we know that oil is relatively very pure hydrocarbon. Using methane as a primary component in the process of petroleum formation is a logical possibility for several reasons. Methane is quite abundant in nature, since the creation of the globe until these days. Furthermore, methane could be transformed into the different components of the crude oil by polymerization. Methane is highly pure hydrocarbon producing highly pure oil components. Methane could migrate easier than kerogen, and be collected in the methane traps (oil traps), since it behaves like water seeping into the lower beds. By mild heat and pressure at the depth methane polymers (oil components) will be formed. Oil is considered to be formed in-situ and not as mentioned in the organic theory, migrating from the kitchen to the oil trap. All the above point of views will be discussing in detail. Alternative ideas which are more logical and more acceptable will be suggested, and it will be the new progress concerning the origin of petroleum, its exploration, and localization.

Emission Theory with Re-Emission of Photons by the Medium—Instead of Special Relativity

Instead of relying on the erroneous principles of Special Relativity, this paper proposes a new theory based on the emission of photons by a source and their re-emission by a transparent medium. Through over 60 articles, we have demonstrated that Special Relativity is based on optical experiments and observations that have been incorrectly explained by the theory of a non-existent ether. Our findings show that all known experiments can be explained using classical concepts of space and time, thereby refuting the theory of relativity. This article also addresses the fallacy of the widely accepted etheric Doppler effects and its significant role in the history of science.

A Comparison of New General System Theory Philosophy With Einstein and Bohr

The New General System theory was developed to be a theory of everything for complex systems within the world we can observe.This theory was constructed by supplementing a new mind-ether ontology into Bertalanffy’s general system theory framework.This theory is basically a generalization of classical mechanics rather than a revolution to it taken both by Einstein and Bohr in developing their relativity theory and quantum mechanics.The purpose of this paper is to reveal the reasons why Einstein and many others fail to unify relativity theory with quantum mechanics through comparing the main differences in philosophical opinions among NGST,Einstein,and Bohr.It is the hope of the authors that this clarification could speed up the unification process.

Black Holes in Hawking's New Theory

科学界的奇才霍金于1975年提出了著名的黑洞理论。根据他的理论,黑洞不仅能吞食光线和物质,还能吞噬信息。尽管当时有些科学家提出疑义,但不为人们所重视。谁知29年之后,霍金本人亲口承认他的黑洞理论有误,因为信息是不能被吞噬的。这是不是有人在愚人节开的玩笑?不!请阅读下面一篇文章。读完之后,你是否同我一样,对霍金更加尊重和崇敬了呢?

The new basic theory on Quaternary environmental research

On the basis of extensive survey to the Quaternary paleosols, soils and weathering layers in the vast northern China and the Loess Plateau, we found some unusually special phenomena of chemical components such as unsuccessive illuvium, twin illuviums, unusually thick illuvium and multi-illuviums etc. According to the analysis on the content of CaCO 3 and the data of penetrating experiment, a new theory of illuvial depth or removal depth of CaCO 3 in weathering and leaching belt was constructed, which indicates that the time of CaCO 3 removing to the illuvial depth is very short, and the effect of time factor on illuvial depth can be ignored. The theory can be taken as a credible foundation for studying many geological and geographical problems in weathering and leaching belt. When the illuvial depth of CaCO 3 is bigger than the thickness of developing belt of soil or paleosol, it can be determined that the paleosol has turned into weathering crust. When the illuvial depth of CaCO 3 is bigger than the thickness of paleosol, paleosol is leaching moderately acid soil. When two, three layers or unusually thick CaCO 3 illuviums exist in the same weathering section or at the bottom of the same paleosol, there were two or more periods forming paleosol and corresponding climatic stages at that time. On the basis of the equation of relationship between mean annual rainfall (y) and illuvial depth of CaCO 3 (x) (y = 305.5x + 168.5) determined in the paper, mean annual precipitation during the development of paleosol can be calculated.

MESHING THEORY AND DESIGN METHOD OF NEW SILENT CHAIN AND SPROCKET

Based on the study of the meshing theory of a new silent chain and sprockets, and the rolling cutting theory of sprocket and hob, the harmonious relations of dominating dimensions among the new silent chain, sprocket and hob is build, the meshing conditions are expatiated, and the resolved expression, which can instruct design and calculation, is educed. The tests show that the meshing design method is feasible.

Study of algorithms of new slender ship theory of wave resistance

In this paper, Noblesse's New Slender-Ship Wave-Making Theory was investigated numerically. Detailed expressions of zeroth and lst order wave resistance have been derived and calculation programs have also been compiled. In the single and double integral terms of Green function, the kernel function of wave resistance expression, special function expansion method and Chebyshev polynomials approach have been adopted respectively, which greatly simplify the calculation and increase the convergence speed.

Re-examination of the Two-Body Problem Using Our New General System Theory

It is well-known that philosophical conflicts exist among classical mechanics,quantum mechanics and relativistic mechanics.In order to use the framework of general system theory to unify these three mechanics subjects,a new general system theory is developed based on a new ontology of ether and minds as the fundamental existences in the world.The two-body problem is the simplest model in mechanics and in this paper,it is re-examined by using our new general system theory.It is found that the current description of the classical full two-body problem is inappropriate since the observer and the measurement apparatus have not been explicitly considered.After considering these,it is actually a three-body problem while only the special case of the Kepler problem is the two-body problem.By introducing the concepts of psychic force and psychic field,all the possible movement states in the two-body problem can be explained within the framework of classical mechanics.There is no need to change the meanings of many fundamental concepts,such as time,space,matter,mass,and energy as done in quantum mechanics and relativity theory.This points out a new direction for the unification of different theories.

New Perspective for the Philosophy of Religion: New Era Theory, Religion and Science

In this article,author expressed the meaning of“belief”,possible effective factors in human life,and how these factors can be effective on person and/or communities.With this respect,the meaning of religion,the possible interaction and relation between religion and science evaluated.42 past/present theories of religion and evaluation of the past/present works of the 87 philosophers of religion are explained.Author considered new synthesis(R-Synthesis),and also new era philosophy,new and re-constructed branches of philosophy,and some systems/constructions to express the new perspective for philosophy of religion.Author applied 27(+)possible definitive/certain result cases of the synthesis for R-Religion discipline specifically,and did the followings under new perspective:(i)eliminated some religious subjects,(ii)unified some religious subjects,(iii)modified some religious subjects,(iv)united some religious subjects in upper phase,(v)separated some religious subject,(vi)defined all religious subjects under one framework,(vii)integrated all religious subjects,(viii)defined new religious subjects,(ix)re-defined some religious subjects,(x)removed some religious subjects and put new religious subjects instead,(xi)added some religious subjects,(xii)kept/protected some religious subjects,(xiii)proposed progression for religious subjects,(xiv)changed the priority of some religious subjects,(xv)increased the importance of some religious subjects,(xvi)strengthened the ethics,(xvii)integrated philosophy branches under one framework,(xviii)others.Some of the purposes of this article are:(i)to define new synthesis method,(ii)to define good and/or correct new perspective and structure for philosophy of religion,science of religion,theories of religion,and related subjects,(iii)to extend the definition/limits of philosophy of religion with new perspective,(iv)others.As result of the synthesis,new perspective for philosophy of religion explained by considering the following concepts/sections:(a)theories of religion,(b)17 upper constructional philosophies and philosophy of religion,(c)eight complementary branches of philosophy of religion,(d)14 lower constructional philosophies and philosophy of religion,(e)science of religion,(f)new theory of religion and its relations with other disciplines.Author defined New Era Theory,New Era Religion,New Era Belief,Progressive Religion and their relations with other religions,beliefs,religious/non-religious movements,and the relation with other theories of religion.Also,power authorities and functional position levels in the New Era Belief,and Religion of God,Knowledge of God/gods,Nature of God/gods concepts are explained generally/specifically.

New Exploration on Theory of Meridian

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Special Issue on New Trends in Theory and Applications of Complex Control Systems

Complexity is one of the leading features of modem control systems. It is caused by the complex properties of controlled plants and the varied requirements in controller designs. In dealing with the control problems with complexity, in the past two decades, a lot of papers have been published that reported fruitful results on different theoretical backgrounds and with different methodologies, such as differential geometry-based design methods, hybrid system theory, switching control, neural network-based intelligent control, etc.

On the Trajectory Prediction of a Throwing Object Using New General System Theory

Trajectory prediction for the movement of a given object is one of the main tasks for the classical mechanics but in orthodox quantum mechanics,this task was announced to be an impossibility for the(sub-)atomic particles by famous Heisenberg’s uncertainty principle.Of course,such an epistemology is against the philosophical beliefs of many scientists and currently another version of trajectory quantum mechanics known as Bohmian mechanics also exists.In order to unify the conflicts among classical mechanics,quantum mechanics,and relativity theory,a new general system theory(NGST)was proposed by the present author and his colleagues.The purpose of this paper is to demonstrate that it is not the scale that matters but the living nature whether the object is lifeless or living.By using the psychic force concept introduced in NGST,Newton’s second law is applied to analyze five different types of objects.They are a stone,a coin,a cat,a person,and an electron.It is found that the classical mechanics has provided adequate room to explain the various newly observed phenomena for orthodox quantum mechanics and relativity theory and for human beings various parapsychological phenomena can also be explained by classical mechanics.Therefore,it is concluded that generalization of classical mechanics is adequate and no need to develop revolutionary quantum mechanics and relativity theory.

A Book Review on The New Edition of Modern Translation Theory by Miq⁃ing Liu

Based on the earlier work Modern Translation Theory,Mr.Liu Miqing has made a great many modifications in The New Edition of Modern Translation Theory.As the book has exerted a far-reaching influence on the translation field,this paper aims to present a relatively comprehensive review of the book and point out its demerits.

Strive to Break New Ground In Human Rights Ideas And Theory

Human Rights, the first international journal specializing in human fights in China, has been officially launched. This is something new in the annals of Chinese publishing history and also a mater of importance in the building of human fights theory in China. The launch of the journal is an indicator of China’s steady opening up and social progress and the healthy development of China’s human fights. For a considerably long period of time after the founding of New China, due to the influence of the ultra-

The New Findings Made in Speech Act Theory

Through carefully studying the theory of speech acts and the literature concerning it,the author made some new findings which reflects in three aspects:the similarities and differences in Chinese and English in expressing the same speech act,the relations between different types of speech acts and the correspondence between sentence sets and sets of speech acts.

MOLECULAR FIELD THEORY FOR NEMATIC LIQUID CRYSTAL POLYMER COMPRISING FLEXIBLE SPACER

Basea on the new model and concept of mtramolecular orientational order parameter, a molecular field theory was built up for main chain liquid crystalline polymer (MC-LCPs) with flexible spacers. The theory takes account of orientational correlation among all mesogens in a polymer chain and the relationship between the intramolecular orientation and spatial orientation of the mesogens. The free energy, temperature and entropy of the nematic-isotropic transition were determined with the theory and compared with experiments in current work. It was found that many unique transition properties of the MC-LCPs comprising flexible spacer are correctly predicted by the theory and the agreement of the theory with the experiments is impressive.

Lie point symmetry algebras and finite transformation groups of the general Broer-Kaup system

Using a new symmetry group theory, the transformation groups and symmetries of the general Broer-Kaup system are obtained. The results are much simpler than those obtained via the standard approaches.

Drivers of Fuel Choice for Cooking among Uganda’s Households

This paper examines the factors that Uganda’s households consider when making fuel choices for cooking and investigates the key drivers of fuel choice. The study adopts a quantitative cross sectional research design. The dependent variable of the empirical model is a qualitative response variable which defines three mutually exclusive and highly differentiated discrete choices for cooking fuels, namely: the traditional fuel (firewood), the transitional fuel (charcoal), and the modern (LPG & electricity). Results from the study show that the most important drivers of fuel choice for cooking in Uganda’s households are: household income, age of household head, gender of household head, marital status, education levels of household head and location of a household. Results also reveal high dependency of firewood as cooking energy source among households in Uganda.