THE chemistry of nitronic esters remains relatively unknown due to their conspicuous feature ofinstability. In the preceding papers, we described the late progress in the researchof nitronic esters: (i) nitronic ester...THE chemistry of nitronic esters remains relatively unknown due to their conspicuous feature ofinstability. In the preceding papers, we described the late progress in the researchof nitronic esters: (i) nitronic esters were first synthesized via O-alkylation of the alkali met-展开更多
The asymmetric aza-Henry reaction of α-substituted nitroacetates and N-Boc imines was achieved with a new-type thioureaguanidine bifunctional organocatalyst.The novel transformations exhibited high diastereoselectivi...The asymmetric aza-Henry reaction of α-substituted nitroacetates and N-Boc imines was achieved with a new-type thioureaguanidine bifunctional organocatalyst.The novel transformations exhibited high diastereoselectivities,and the adducts bearing adjacent quaternary and tertiary chiral centers were generally obtained in moderate to good enantioselectivities（up to 88%ee）.展开更多
文摘THE chemistry of nitronic esters remains relatively unknown due to their conspicuous feature ofinstability. In the preceding papers, we described the late progress in the researchof nitronic esters: (i) nitronic esters were first synthesized via O-alkylation of the alkali met-
基金the Scientific Research Fund ofSichuan Provincial Education Department(No.310-347)Technology Department of Chengdu University of TCM(Nos.310-446 and 310-448)for financial support
文摘The asymmetric aza-Henry reaction of α-substituted nitroacetates and N-Boc imines was achieved with a new-type thioureaguanidine bifunctional organocatalyst.The novel transformations exhibited high diastereoselectivities,and the adducts bearing adjacent quaternary and tertiary chiral centers were generally obtained in moderate to good enantioselectivities（up to 88%ee）.
