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MINIMIZING EXCITATION LIGHT LEAKAGE AND MAXIMIZING MEASUREMENT SENSITIVITY FOR MOLECULAR IMAGING WITH NEAR-INFRARED FLUORESCENCE
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作者 BANGHE ZHU EVA M.SEVICK-MURACA 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2011年第3期301-307,共7页
Near-infraredfluorescence(NIRF)imaging involves the separation of weakfluorescence signals from backscattered excitation light.The measurement sensitivity of current NIRF imaging systems is limited by the excitation l... Near-infraredfluorescence(NIRF)imaging involves the separation of weakfluorescence signals from backscattered excitation light.The measurement sensitivity of current NIRF imaging systems is limited by the excitation light leakage through rejectionfilters.In this contribution,the authors demonstrate that the excitation light leakage can be suppressed upon using appropriatefilter combination and permutations.The excitation light leakage and measurement sensitivity were assessed and compared in this study by computing the transmission ratios of excitation to emission light collected and the signal-to-noise ratios in well-controlled phantom studies with differentfilter combinations and permutations.Using appropriatefilter combinations and permutations,we observe as much as two orders of magnitude reduction in the transmission ratio and higher signal-to-noise ratio. 展开更多
关键词 Molecular imaging FLUORESCENCE opticalfilter excitation light leakage noise floor
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从中国首台紫外-可见光高光谱卫星仪器反演得到的高空间分辨率臭氧廓线
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作者 Fei Zhao Cheng Liu +3 位作者 Qihou Hu Congzi Xia Chengxin Zhang Wenjing Su 《Engineering》 SCIE EI CAS 2024年第1期106-115,共10页
Understanding the vertical distribution of ozone is crucial when assessing both its horizontal and vertical transport,as well as when analyzing the physical and chemical properties of the atmosphere.One of the most ef... Understanding the vertical distribution of ozone is crucial when assessing both its horizontal and vertical transport,as well as when analyzing the physical and chemical properties of the atmosphere.One of the most effective ways to obtain high spatial resolution ozone profiles is through satellite observations.The Environmental Trace Gases Monitoring Instrument(EMI)deployed on the Gaofen-5 satellite is the first Chinese ultraviolet-visiblehyperspectralspectrometer.However,retrieving ozone profiles using backscattered radiance values measured by the EMI is challenging due to unavailable measurement errors and a low signal-to-noise ratio.The algorithm developed for the Tropospheric Monitoring Instrument did not allow us to retrieve 87%of the EMI pixels.Therefore,we developed an algorithm specific to the characteristics of the EMI.The fitting residuals are smaller than 0.3%in most regions.The retrieved ozone profiles were in good agreement with ozonesonde data,with maximum mean biases of 20%at five latitude bands.By applying EMI averaging kemels to the ozonesonde profiles,the integrated stratospheric column ozone and tropospheric column ozone also showed excellent agreement with ozo-nesonde data.The lower layers(0-7.5 km)of the EMI ozone profiles reflected the seasonal variation in surface ozone derived from the China National Environmental Monitoring Center(CNEMC).However,the upper layers(9.7-16.7 km)of the ozone profiles show different trends,with the ozone peak occurring at an altitude of 9.7-16.7 km in March,2019.A stratospheric intrusion event in central China from August 11 to 15,2019,is captured using the EMI ozone profiles,potential vorticity data,and relative humidity data.The increase in the CNEMC ozone concentration showed that downward transport enhanced surface ozone pollution. 展开更多
关键词 Ozone profiles EMI Soft calibration floor noise correction Stratospheric ozone intrusion
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