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基于Transformer-LSTM网络的轴承寿命预测 被引量:1
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作者 张帆 姚德臣 +4 位作者 姚圣卓 杨建伟 王琰亮 魏明辉 胡忠硕 《振动与冲击》 EI CSCD 北大核心 2024年第6期320-328,共9页
轴承是旋转机械设备中的重要部件,由于工况、材质、加工方式等原因,轴承寿命时长相差许多。传统的并行或串行神经网络预测方式,对数据集有一定要求。因此,需要一种能够适用于不同数据长短的轴承剩余使用寿命预测网络。为此提出了一种能... 轴承是旋转机械设备中的重要部件,由于工况、材质、加工方式等原因,轴承寿命时长相差许多。传统的并行或串行神经网络预测方式,对数据集有一定要求。因此,需要一种能够适用于不同数据长短的轴承剩余使用寿命预测网络。为此提出了一种能够预测不同寿命时长的Transformer-LSTM串并行神经网络预测模型。通过将Transformer解码层进行重构,并与长短期记忆时序神经网络(long short-term memory,LSTM)网络结构融合,实现轴承寿命数据的串并行预测处理。试验结果表明Transformer-LSTM神经网络能够精准预测长、中、短不同寿命时长的轴承失效时间,具有较强的模型泛化能力,提升轴承寿命预测精度与模型的泛化能力。 展开更多
关键词 滚动轴承 轴承寿命预测 Transformer神经网络 LSTM神经网络 非线性时间序列预测
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Optimal Design of Multiple Stress Constant Accelerated Life Test Plan on Non-rectangle Test Region 被引量:8
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作者 CHEN Wenhua GAO Liang +2 位作者 LIU Juan QIAN Ping PAN Jun 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2012年第6期1231-1237,共7页
For optimal design of constant stress accelerated life test(CSALT) with two-stress, if the stresses could not reach the highest levels simultaneously, the test region becomes non-rectangular. For optimal CSALT desig... For optimal design of constant stress accelerated life test(CSALT) with two-stress, if the stresses could not reach the highest levels simultaneously, the test region becomes non-rectangular. For optimal CSALT design on non-rectangle test region, the present method is only focused on non-rectangle test region with simple boundary, and the optimization algorithm is based on experience which can not ensure to obtain the optimal plan. In this paper, considering the linear-extreme value model and the optimization goal to minimize the variance of lifetime estimate under normal stress, the optimal design method of two-stress type-I censored CSALT plan on general non-rectangular test region is proposed. First, two properties of optimal test plans are proved and the relationship of all the optimal test plans is determined analytically. Then, on the basis of the two properties, the optimal problem is simplified and the optimal design method of two-stress CSALT plan on general non-rectangular test region is proposed. Finally, a numerical example is used to illustrate the feasibility and effectiveness of the method, The result shows that the proposed method could obtain the optimal test plan on non-rectangular test regions with arbitrary boundaries. This research provides the theory and method for two-stress optimal CSALT planning on non-rectangular test regions. 展开更多
关键词 accelerated life test non- rectangular test region test plan optimal design
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An Extension of One-Period Nash Equilibrium Model in Non-Life Insurance Markets 被引量:1
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作者 G. Battulga L. Altangerel G. Battur 《Applied Mathematics》 2018年第12期1339-1350,共12页
This paper deals with an extension of the one-period model in non-life insurance markets (cf. [1]) by using a transition probability matrix depending on some economic factors. We introduce a multi-period model and in ... This paper deals with an extension of the one-period model in non-life insurance markets (cf. [1]) by using a transition probability matrix depending on some economic factors. We introduce a multi-period model and in each period the solvency constraints will be updated. Moreover, the model has the inactive state including some uninsured population. Similar results on the existence of premium equilibrium and sensitivity analysis for this model are presented and illustrated by numerical results. 展开更多
关键词 NASH Equilibrium MODEL Variational INEQUALITIES Transition Matrix non-life INSURANCE MARKETS
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A Statistical Analysis of Intensities Estimation on the Modeling of Non-Life Insurance Claim Counting Process 被引量:1
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作者 Uraiwan Jaroengeratikun Winai Bodhisuwan Ampai Thongteeraparp 《Applied Mathematics》 2012年第1期100-106,共7页
This study presents an estimation approach to non-life insurance claim counts relating to a specified time. The objective of this study is to estimate the parameters in non-life insurance claim counting process, inclu... This study presents an estimation approach to non-life insurance claim counts relating to a specified time. The objective of this study is to estimate the parameters in non-life insurance claim counting process, including the homogeneous Poisson process (HPP) and the non-homogeneous Poisson process (NHPP) with a bell-shaped intensity. We use the estimating function, the zero mean martingale (ZMM) as a procedure of parameter estimation in the insurance claim counting process. Then, Λ(t) , the compensator of is proposed for the number of claims in the time interval . We present situations through a simulation study of both processes on the time interval . Some examples of the situations in the simulation study are depicted by a sample path relating to its compensator Λ(t). In addition, an example of the claim counting process illustrates the result of the compensator estimate misspecification. 展开更多
关键词 Estimating Function Zero Mean MARTINGALE non-life INSURANCE CLAIM Counting PROCESS Poisson PROCESS Bell-Shaped Intensity
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Patient-Reported Outcomes of Surgery of Non-Small Cell Lung Cancer: Evaluation Based on the Questionnaires of Anti-Aging Quality of Life and the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire 被引量:1
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作者 Takanori Ayabe Masaki Tomita +2 位作者 Naohiro Nose Takashi Asada Kunihide Nakamura 《Surgical Science》 2017年第5期203-219,共17页
Background: Patient-reported outcomes of the quality of life (QOL) after an open thoracotomy have not been studied. To determine the physical and mental changes in surgical patients is very important for medical staff... Background: Patient-reported outcomes of the quality of life (QOL) after an open thoracotomy have not been studied. To determine the physical and mental changes in surgical patients is very important for medical staffs. The surgical patient’s satisfaction and overall healthy changes were evaluated by the patient-self assessment questionnaires. Materials and Methods: From July 2007 to April 2008, 26 patients with non-small cell lung cancer (NSCLC) underwent surgical resection. The outcome of the QOL was evaluated by using two kinds of questionnaire surveys from the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and the anti-aging QOL assessment (AA-QOL). The EORTC QLQ-C30 consisted of five domains (physical, role, cognitive, emotional, and social functionings) and global QOL. The AA-QOL contained 51 items;30 physical and 21 mental symptoms regarding the elderly and the aging population. The patients replied to the two questionnaires at two different times, i.e., at pre-surgery (baseline) and at post-surgery (2 weeks after the operation). The obtained data of these scores were averaged and compared between the two points of the pre-surgery and post-surgery. Results: Regarding the outcomes of the EORTC QLQ-C30, the physical and social functioning became significantly worse after the surgery. In contrast, the global QOL significantly became better after the surgery. For the symptom at post-surgery, three of which were “nausea and vomiting”, “pain”, and “appetite loss”, became significantly worse compared to those at pre-surgery. Regarding the outcomes of the AA-QOL, the physical symptoms (muscular pain/stiffness, palpitations, dyspnea, no feeling of good health, anorexia, and coughing and sputum) became significantly worse after the surgery. Regarding the mental symptoms, there were no significant differences. Conclusions: Regarding the outcomes based on the changes in the QOL after surgery, the physical symptoms became worse compared to the mental symptoms. To clarify the perioperative healthy changes of the QOL reported by patients with lung cancers is very important for multidisciplinary teamwork, which should play a role in providing the appropriate care and treatment and useful information for a preoperative patient’s decision making of receiving surgical treatment. 展开更多
关键词 Patient-Reported OUTCOME SURGERY Quality of life non-SMALL Cell LUNG Cancer
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A Bayesian Inference of Non-Life Insurance Based on Claim Counting Process with Periodic Claim Intensity
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作者 Uraiwan Jaroengeratikun Winai Bodhisuwan Ampai Thongteeraparp 《Open Journal of Statistics》 2012年第2期177-183,共7页
The aim of this study is to propose an estimation approach to non-life insurance claim counts related to the insurance claim counting process, including the non-homogeneous Poisson process (NHPP) with a bell-shaped in... The aim of this study is to propose an estimation approach to non-life insurance claim counts related to the insurance claim counting process, including the non-homogeneous Poisson process (NHPP) with a bell-shaped intensity and a beta-shaped intensity. The estimating function, such as the zero mean martingale (ZMM), is used as a procedure for parameter estimation of the insurance claim counting process, and the parameters of model claim intensity are estimated by the Bayesian method. Then,Λ(t), the compensator of N(t) is proposed for the number of claims in a time interval (0,t]. Given the process over the time interval (0,t]., the situations are presented through a simulation study and some examples of these situations are also depicted by a sample path relating N(t) to its compensatorΛ(t). 展开更多
关键词 Estimating Function Zero Mean MARTINGALE non-life Insurance CLAIM Counting PROCESS non-Homogeneous Poisson PROCESS Bell-Shaped INTENSITY Beta-Shaped INTENSITY
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Effect of TCM Combined with Chemotherapy on Immune Function and Quality of Life of Patients with Non-small Cell Lung Cancer inStage Ⅲ-Ⅳ
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作者 杨祖贻 吴雪梅 +3 位作者 欧亚龙 余萍 罗洁 宋秀云 《Chinese Journal of Integrated Traditional and Western Medicine》 SCIE CAS 2004年第3期181-186,共6页
Objective: To observe and compare the effect of traditional Chinese medicine (TCM) combined with chemotherapy (CT) on immune function and quality of life (QOL)of patients with non-small cell lung cancer (NSCLC) in sta... Objective: To observe and compare the effect of traditional Chinese medicine (TCM) combined with chemotherapy (CT) on immune function and quality of life (QOL)of patients with non-small cell lung cancer (NSCLC) in stage Ⅲ-Ⅳ. Methods: One hundred cases with stage Ⅲ-Ⅳ NSCLC were randomly divided into two groups. The treated group (n=50) received CT combined with TCM, and the control group received CT alone. The percentage of T lymphocyte subset in peripheral blood and the change of natural killer (NK) cell count were observed after treatment. The QOL and tolerance of CT were also compared between the two groups after treatment. Results: In the treated group, CD3 cell count, CD4 cell count, CD4/ CDg ratio and NK cell activity were higher than those in control group, while CD8 cell count in the treated group was lower than that in the control group (P<0.05), and QOL and tolerance of CT in the treated group were also better (P<0.05). Conclusion: TCM combined with CT could raise the patients' ability in tolerating CT in stage Ⅲ-ⅣNSCLC. 展开更多
关键词 non-small cell lung cancer in stage - traditional Chinese medicine combined with chemotherapy immune function quality of life
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An aqueous BiI_(3)-Zn battery with dual mechanisms of Zn^(2+)(de)intercalation and I^(-)/I_(2)redox
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作者 Qi Deng Fangzhong Liu +3 位作者 Xiongwei Wu Changzhu Li Weibin Zhou Bei Long 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第2期670-678,I0014,共10页
The development of aqueous battery with dual mechanisms is now arousing more and more interest.The dual mechanisms of Zn^(2+)(de)intercalation and I^(-)/I_(2)redox bring unexpected effects.Herein,differing from previo... The development of aqueous battery with dual mechanisms is now arousing more and more interest.The dual mechanisms of Zn^(2+)(de)intercalation and I^(-)/I_(2)redox bring unexpected effects.Herein,differing from previous studies using Zn I_(2)additive,this work designs an aqueous Bi I_(3)-Zn battery with selfsupplied I^(-).Ex situ tests reveal the conversion of Bi I_(3)into Bi(discharge)and Bi OI(charge)at the 1st cycle and the dissolved I^(-)in electrolyte.The active I^(-)species enhances the specific capacity and discharge medium voltage of electrode as well as improves the generation of Zn dendrite and by-product.Furthermore,the porous hard carbon is introduced to enhance the electronic/ionic conductivity and adsorb iodine species,proven by experimental and theoretical studies.Accordingly,the well-designed Bi I_(3)-Zn battery delivers a high reversible capacity of 182 m A h g^(-1)at 0.2 A g^(-1),an excellent rate capability with 88 m A h g^(-1)at 10 A g^(-1),and an impressive cyclability with 63%capacity retention over 20 K cycles at 10 A g^(-1).An excellent electrochemical performance is obtained even at a high mass loading of 6 mg cm^(-2).Moreover,a flexible quasi-solid-state Bi I_(3)-Zn battery exhibits satisfactory battery performances.This work provides a new idea for designing high-performance aqueous battery with dual mechanisms. 展开更多
关键词 Aqueous BiI_(3)-Zn battery Dual mechanisms I^(-)-induced uniform zinc deposition Ultralong cyclic life Flexible quasi-solid-state battery
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Are the data on quality of life and patient reported outcomes from clinical trials of metastatic non-small-cell lung cancer important?
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作者 Vera Hirsh 《World Journal of Clinical Oncology》 CAS 2013年第4期82-84,共3页
Majority of the patients with advanced non-small-cell lung cancer(NSCLC)experience two or more disease related symptoms,which may have a negative impact on their health-related quality of life(HR QOL).These patients p... Majority of the patients with advanced non-small-cell lung cancer(NSCLC)experience two or more disease related symptoms,which may have a negative impact on their health-related quality of life(HR QOL).These patients prefer a therapy that would improve disease related symptoms,as opposed or treatment that slightly prolongs their survival without improving symptoms.The improvements of the symptoms augment the significance of improved response rates or progression free survivals.The choice of the questionnaires to evaluate patients-reported outcomes(PROs)and HRQOL benefits and methods of collecting the data and their interpretations are very important and are discussed in this manuscript.PROs and HR QOL outcomes are important in patients with advanced NSCLC only when the data are collected and analyzed correctly.Then they can be viewed as components of the total value of a treatment,providing a comprehensive picture of the benefits and risks of anticancer therapies.Enabling the patients to feel during the last months of their lives more comfortable and not be dependent on their loved ones is a very important task in the treatment of advanced NSCLC. 展开更多
关键词 Quality of life Clinical trials non-SMALL cell LUNG cancer Patient reported OUTCOMES
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Patient-Reported Outcomes of Chemotherapy Involving Non-Small Cell Lung Cancer: Evaluation by Questionnaires of Quality of Life Regarding Anti-Aging and Anti-Cancer Drugs
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作者 Takanori Ayabe Masaki Tomita +3 位作者 Takashi Asada Kazuyo Tsuchiya Manabu Nemoto Kunihide Nakamura 《Advances in Lung Cancer》 2017年第2期13-35,共23页
Background: Patient-reported outcomes (PROs) of quality of life (QOL) during chemotherapy involving lung cancer are very important for the medical staffs. Patients’ satisfaction and healthy changes were evaluated by ... Background: Patient-reported outcomes (PROs) of quality of life (QOL) during chemotherapy involving lung cancer are very important for the medical staffs. Patients’ satisfaction and healthy changes were evaluated by the patient-self assessment. Materials and Methods: From July 2007 to April 2008, a total of 19 patients received chemotherapy. The QOL data were collected by using the QOL questionnaire for cancer patients treated with anticancer drugs (QOL-ACD) and the anti-aging QOL assessment (AA-QOL). The AA-QOL contained 51 items: 30 of physical and 21 of mental symptoms of the elderly and the aging population. The patients replied to the questions at two different times, i.e., at pre-chemotherapy (baseline) and at post-chemotherapy (2 weeks after the chemotherapy). Results: Regarding the hematological toxicities, for the grade 3/4 toxicities, there were 12 neutropenia (12/19, 63.2%) and 3 thrombocytopenia (3/19, 15.8%). For the grade 3 febrile neutropenia, there were 5 cases (5/19, 26.3%). Regarding the non-hematological toxicities, there was no grade 3 and grade 4 toxicities. Based on the outcomes of the QOL-ACD, the three items (“physical condition”, “social attitude”, and “overall QOL”) at post-chemotherapy became significantly worse compared to the baseline. Regarding the outcomes of the AA-QOL, 4 items of physical symptoms (“thirst”, “anorexia”, “early satiety”, and “diarrhea”) became significantly worse compared to the baseline. Regarding the mental symptoms, 2 items (“nothing to look forward in life” and “a sense of uselessness”) became significantly worse compared to the baseline. Conclusion: Regarding the PROs of the QOL during the chemotherapy term, both the physical and mental symptoms had become worse. To clarify the changes in the QOL during chemotherapy is very important for multidisciplinary teamwork, which should play the role of providing the appropriate cares and treatment as patient-support. 展开更多
关键词 Patient-Reported OUTCOME CHEMOTHERAPY Quality of life non-SMALL Cell LUNG Cancer
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Outcomes of Quality of Life Regarding the Next-Generation Thoracoscopic Intrapleural Hyperthermic Chemotherapy of Non-Small Cell Lung Cancer with Dissemination 被引量:2
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作者 Takanori Ayabe Masaki Tomita +2 位作者 Eiichi Chosa Kosuke Mori Kunihide Nakamura 《Journal of Cancer Therapy》 2016年第1期63-77,共15页
Background: We have developed a new next-generation intrapleural hyperthermic chemotherapy (IPHC) for non-small cell lung cancer with dissemination, which is a hybrid chemotherapy combined with oral S-1 medication plu... Background: We have developed a new next-generation intrapleural hyperthermic chemotherapy (IPHC) for non-small cell lung cancer with dissemination, which is a hybrid chemotherapy combined with oral S-1 medication plus conventional cisplatin-based IPHC. We now report the preliminary feasibility and outcome of quality of life (QOL) regarding this hybrid IPHC. Methods: The patient was a 76-year-old male with a 2-cm nodule in the left upper lobe. After partial resection by video-assisted thoracic surgery (VATS), which was diagnosed with advanced pulmonary adenocarcinoma with intrapleural dissemination. We initially performed two regimens of systemic chemotherapy, S-1 (day 1 - 21, 100 mg 2X/day) + CDDP (day 8, 60 mg/m<sup>2</sup>) and S-1 (day 1 - 14,100 mg 2X/day) + CBDCA (day 1, AUC 5). The regimen of next-generation IPHC is oral S-1 medication (day 1 - 21, 100 mg/day) + intrapleural hyperthermic perfusion of cisplatin (200 mg/m<sup>2</sup>) with VATS (day 8,43°C, 2 hours). Adverse outcomes, QOL, and pleural effusion were assessed in three regimens. To investigate the outcomes of the QOL, the European Organization for Research and Treatment of Cancer QOL Questionnaire (EORTC QLQ-C30 and QLQ-LC13), the QOL questionnaire for cancer patients treated with anticancer drugs (QOL-ACD), the Cancer Dyspnea Score (CDS), and the St. George’s Respiratory Questionnaire (SGRQ) were used. Results: During the IPHC treatment course, grade 3 neutropenia, anemia, and diarrhea were observed. The physical function after IPHC became worse compared to that before the IPHC. Fatigue during chemotherapy (CBDCA+S-1) was more pronounced than that during the IPHC. Nausea, vomiting, and diarrhea during the IPHC were prevalent than those of chemotherapy. The overall QOL after the IPHC was improved compared to that before the IPHC. Regarding before and after the IPHC, the physical function after the IPHC became worse compared to that before the IPHC, on the other hand, the global QOL before and after the IPHC had not dramatically changed. Pleural effusion was controlled after the IPHC for more than 1 year. Conclusion: The first case of a clinical trial of the next-generation IPHC showed grade 3 adverse events. However, it was an acceptable feasibility compared to the usual platinum doublet chemotherapy. The effectiveness of the IPHC allowed the patient to obtain a good control of the pleural effusion and preserved the patient’s QOL. 展开更多
关键词 non-Small Cell Lung Cancer INTRAPLEURAL Hyperthermic Chemotherapy CISPLATIN S-1 Quality of life
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Sustaining Increase in Life Expectancy in Africa Requires Active Preventive Measures against Non-Communicable Diseases
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作者 Efosa K. Oghagbon Lydia Giménez-Llort 《Open Journal of Preventive Medicine》 2014年第5期283-292,共10页
It is projected that aged population (≥60 years) will continue to increase globally, including in Africa. This is due to reduced population growth, decreased fecundity and improved medical interventions;factors which... It is projected that aged population (≥60 years) will continue to increase globally, including in Africa. This is due to reduced population growth, decreased fecundity and improved medical interventions;factors which increase life expectancy. While this is typical for developed countries, it is not the same for Africa and similar developing regions. In these regions, a significant proportion of death is due to non-communicable diseases (NCD’s) such as hypertension, cerebrovascular accident, coronary heart disease, diabetes mellitus, chronic renal disease and cancer, among others. Rising prevalence of NCD’s due mainly to western style diets and sedentary living is made worse by inadequate nutrition education, high prevalence of low birth weight, poor health services, lack of efficient tobacco control and deficient planning of built environment. In order to halt the possible reduction in life expectancy occasioned by NCD’s, efforts by the community, health planners and governments in Africa to address relevant NCD’s, must be put in place. Suggested measures are: nutrition education, regular community directed physical exercise, improved environmental planning and development. Others are review of present health service model, early detection, prevention and treatment of NCD’s, including improved antenatal care to reduce low birth weights, and establishment of policies and measures that decreased access to tobacco especially by women of childbearing age. Africa and similar developing regions cannot fund the health bill due to NCD’s and their complications;hence it is important that this scourge is attended to with all seriousness. 展开更多
关键词 life EXPECTANCY Developing COUNTRIES non-Communicable Diseases Prevention Community Role and Health System Review
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感恩拓延--建构理论下多维度支持对老年非小细胞肺癌化疗患者心理状态和生活质量的影响
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作者 戴丽君 仲巧玲 洪虹 《老年医学与保健》 CAS 2024年第5期1371-1376,1387,共7页
目的分析感恩拓延--建构理论下多维度支持对老年非小细胞肺癌(NSCLC)化疗患者心理状态和生活质量的影响。方法选取2022年1月—2023年12月就诊于江苏省海安市中医院的老年NSCLC化疗患者120例,采用随机数字表法分为对照组和观察组,每组60... 目的分析感恩拓延--建构理论下多维度支持对老年非小细胞肺癌(NSCLC)化疗患者心理状态和生活质量的影响。方法选取2022年1月—2023年12月就诊于江苏省海安市中医院的老年NSCLC化疗患者120例,采用随机数字表法分为对照组和观察组,每组60例。2组采用相同的治疗,对照组给予常规护理,观察组在对照组常规护理的基础上给予感恩拓延--建构理论下多维度支持,均持续干预2个月。比较干预前后2组的癌因性疲乏、自我护理能力、感恩水平、心理状态[采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评分]以及生活质量的变化。结果干预后,观察组的CFS总分及各维度评分、SAS及SDS评分均低于对照组(P<0.05),而观察组的ESCA各维度评分、CQ-6评分及QLQ-C30各维度评分均高于对照组(P<0.05)。结论感恩拓延--建构理论下的多维度支持可有效缓解老年NSCLC化疗患者的癌因性疲乏、焦虑及抑郁,提高自我护理能力及生活质量,并提升感恩水平,具有一定的临床应用价值。 展开更多
关键词 老年 非小细胞肺癌 化疗 感恩拓延--建构理论 多维度支持 心理状态 生活质量
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基于日常生活视角的农转非社区公共空间使用研究--以重庆市礼嘉街道嘉和社区为例
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作者 徐苗 杨雪梅 《西部人居环境学刊》 CSCD 2023年第6期89-97,共9页
城镇化进程蚕食乡村地区所引发的传统居住空间变迁,使城市边缘区的农转非社区面临社会空间重构。这类社区的公共空间完全按照城市居住景观来修建,但居民延续了很多农村原有的生活习惯与社区文化,与周边城市在空间上的同质化和社区居民... 城镇化进程蚕食乡村地区所引发的传统居住空间变迁,使城市边缘区的农转非社区面临社会空间重构。这类社区的公共空间完全按照城市居住景观来修建,但居民延续了很多农村原有的生活习惯与社区文化,与周边城市在空间上的同质化和社区居民与“城里人”的异质性导致按城市住区景观设计的农转非社区公共空间与社区居民日常活动的不适配。因此,本文首先回顾了我国农转非社区的形成、社会异质性与空间同质化特征,并梳理了国内外异质社区公共空间适配性的相关研究;其次,基于对重庆市嘉和社区的田野调研,从公共空间属性与使用两个层面,分析了农转非社区居民的日常活动特征与公共空间的运行机制,评析了各项公共空间资源配置与利用率、聚集性以及活动类型之间的适配关系,探讨了影响农转非社区公共空间配置与设计与居民日常活动需求失衡的原因,为国内农转非社区更新,尤其是农转非社区公共空间质量的提升提供科学依据和政策建议。 展开更多
关键词 农转非社区 公共空间 适配性 日常生活
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肥胖儿童non-HDL-C、remnant cholesterol与亚临床动脉粥样硬化的关系 被引量:4
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作者 焦朝艳 刘戈力 +4 位作者 鲍鹏丽 魏莹 杨箐岩 郑荣秀 赵菁 《天津医科大学学报》 2014年第1期25-28,共4页
目的:了解non-HDL-C和remnant cholesterol与肥胖儿童亚临床动脉粥样硬化(AS)的关系。方法:根据甘油三酯(TG)水平将65例肥胖儿童(肥胖组)分为I组(TG≥2.3 mmol/L)32例,II组(TG<2.3 mmol/L)33例,与肥胖组儿童性别年龄相匹配的正常体... 目的:了解non-HDL-C和remnant cholesterol与肥胖儿童亚临床动脉粥样硬化(AS)的关系。方法:根据甘油三酯(TG)水平将65例肥胖儿童(肥胖组)分为I组(TG≥2.3 mmol/L)32例,II组(TG<2.3 mmol/L)33例,与肥胖组儿童性别年龄相匹配的正常体质量儿童30例为III组(对照组)。比较3组儿童血脂指标,对肥胖组各项血脂指标与血浆致动脉粥样硬化指数(AIP)进行相关性分析,肥胖患儿体质指数、血脂指标与颈动脉内径、内膜-中层厚度(c-IMT)、血流参数进行相关性分析。结果:I组、II组的TG、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、non-HDL-C、remnant cholesterol、AIP均较对照组升高,高密度脂蛋白胆固醇(HDL-C)较对照组降低,且I组的remnant cholesterol、AIP均较II组升高。肥胖组儿童AIP与TG、non-HDL-C、remnant cholesterol呈正相关,与HDL-C呈负相关。37例行颈动脉超声检查的肥胖儿童的c-IMT较正常儿童的增厚。结论:non-HDL-C、remnant cholesterol在肥胖儿童亚临床AS中有重要作用,在肥胖儿童血脂异常的治疗中应关注non-HDL-C、remnant cholesterol的变化。 展开更多
关键词 儿童肥胖 亚临床动脉粥样硬化 non—HDL—C REMNANT CHOLESTEROL 血浆致动脉粥样硬化指数 颈动脉内膜-中层厚度
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Improvement of Quality of Life with Shenfu Injection (参附注射液) in Non Small Cell Lung Cancer Patients Treated with Gemcitabine plus Cisplatin Regimen 被引量:7
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作者 吴万垠 龙顺钦 +6 位作者 张海波 柴小姝 邓宏 薛晓光 王斌 罗海英 刘伟胜 《Chinese Journal of Integrated Traditional and Western Medicine》 2006年第1期50-54,共5页
Objective: To observe the effect of Shenfu injection (参附注射液, SFI) in treating non small cell lung cancer (NSCLC) patients on quality of life with gemcitabine (GEM) plus cisplatin (GP) regimen. Methods: ... Objective: To observe the effect of Shenfu injection (参附注射液, SFI) in treating non small cell lung cancer (NSCLC) patients on quality of life with gemcitabine (GEM) plus cisplatin (GP) regimen. Methods: Thirty-four patients were ready to receive GP regimen chemotherapy for treating NSCLC disease, according to lot-drawing, they were divided into SFI pre-treatment group (18 cases) and SFI post-treatment group ( 16 cases). SFI pre-treatment group: During the first treatment course, chemotherapy was begun with SFI 60 ml, intravenous dripping on the 3rd day, once daily, consecutively for 10 days; on the 1st day, GP regimen (GEM 1250 mg/m^2 , intravenous dripping, on the 1st and 8th day; cisplatin 70 mg/m^2 on the 2nd day; 21 days as one cycle) was carried out; in the second treatment course GP regimen was merely given to serve as the self-control. SFI post-treatment group: the medicament sequence order was reversed from that of pre-treatment group. Using dual international quality of life (QOL) scores, the effect of SFI on the patients" QOL was observed through randomized self pre- and post- crossover control. Results: The QOL in the 34 patients after being treated by SFI in combination with GP chemotherapy regimen in one group, and GP chemotherapy regimen alone in the other, was improved in different degrees, with significant difference (P〈0.01); comparision of SFI combined with GP chemotherapy regimen with GP chemotherapy alone showed that QOL in patients was significantly different (P〈0.01). Conclusion: SFI could improve QOL in patients with NSCLC who were treated with GP regimen. 展开更多
关键词 Shenfu injection non small cell lung cancer GEMCITABINE CISPLATIN quality of life
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A two-parameter model to predict fatigue life of high-strength steels in a very high cycle fatigue regime 被引量:7
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作者 Chengqi Sun Xiaolong Liu Youshi Hong 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2015年第3期383-391,共9页
In this paper, ultrasonic (20 kHz) fatigue tests were performed on specimens of a high-strength steel in very high cycle fatigue (VHCF) regime. Experimental results showed that for most tested specimens failed in ... In this paper, ultrasonic (20 kHz) fatigue tests were performed on specimens of a high-strength steel in very high cycle fatigue (VHCF) regime. Experimental results showed that for most tested specimens failed in a VHCF regime, a fatigue crack originated from the interior of specimen with a fish-eye pattern, which contained a fine granular area (FGA) centered by an inclusion as the crack origin. Then, a two-parameter model is proposed to predict the fatigue life of high-strength steels with fish-eye mode failure in a VHCF regime, which takes into account the inclusion size and the FGA size. The model was verified by the data of present experiments and those in the literature. Furthermore, an analytic formula was obtained for estimating the equivalent crack growth rate within the FGA. The results also indicated that the stress intensity factor range at the front of the FGA varies within a small range, which is irrespective of stress amplitude and fatigue life. 展开更多
关键词 Very high-cycle fatigue - High-strength steels Fatigue life Inclusion size Crack growth rate
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316L不锈钢non-Masing特性分析和疲劳寿命预测 被引量:4
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作者 金丹 左皓中 +2 位作者 刘兵 吕春堂 娄天培 《中国机械工程》 EI CAS CSCD 北大核心 2020年第24期2931-2936,共6页
对316L不锈钢在不同应变范围下分别进行了293 K和873 K试验温度下的低周疲劳试验,讨论了材料循环特性的幅值相关性和温度相关性,比较了不同条件下non-Masing特性,并利用能量方法进行了低周疲劳寿命预测。实验结果表明,在不同条件下,循... 对316L不锈钢在不同应变范围下分别进行了293 K和873 K试验温度下的低周疲劳试验,讨论了材料循环特性的幅值相关性和温度相关性,比较了不同条件下non-Masing特性,并利用能量方法进行了低周疲劳寿命预测。实验结果表明,在不同条件下,循环初期会出现不同程度的循环硬化现象,随后会出现循环软化、饱和直至材料失效;与873 K试验条件相比,材料在293 K温度下的non-Masing特性更为显著;在大应变范围下,两温度下材料的non-Masing特性更加明显。采用能量方法进行疲劳寿命预测时,预测结果均位于两倍分散带内,且基于non-Masing特性得到了比基于Masing特性更为精确的预测结果。在873 K温度和大应变范围下,显著的动态应变时效效应导致考虑non-Masing与Masing特性的预测结果相差不大。 展开更多
关键词 316L不锈钢 non-Masing特性 疲劳寿命预测 动态应变时效
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Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced non-small cell lung cancer: a meta-analysis 被引量:13
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作者 Qiang Zhang Yi-Huan Fan +2 位作者 Teng Zhang Xiao-Lan Qin Ji-Fang Song 《TMR Integrative Medicine》 2017年第2期68-78,共11页
Objective: To evaluate the clinical efficacy of Shenqi Fuzheng injection combined with gemcitabine plus cisplatin(GP) in the treatment of advanced non-small cell lung cancer (NSCLC). Methods: we performed a syst... Objective: To evaluate the clinical efficacy of Shenqi Fuzheng injection combined with gemcitabine plus cisplatin(GP) in the treatment of advanced non-small cell lung cancer (NSCLC). Methods: we performed a systematicsearch in the electronic databases such as Cochrane Library, Pubmed, Embase, Chinese Journal Full-text Database,Chinese Biomedical Literature Database, Chinese Science and Technology Periodical Full-text Database andWanfang Database up to 30 January 2017. Randomized controlled trials (RCT) of Shenqi Fuzheng Injectioncombined with GP chemotherapy in the treatment of advanced NSCLC were searched, and all the RCTs wereconducted on methodological quality assessment. Data extraction and data analysis were according to standards ofCochrane systematic review. Results: Eight trials were included including a total of 701 patients. Meta-analysisresults: Shenqi Fuzheng injection combined with GP chemotherapy could significantly improve the functionalstatus of patients with NSCLC (OR = 3.44, 95% CI [2.26, 5.25], P 〈 0.0001) and clinical treatment efficacy (OR =(OR = 0.31, 95%CI [0.20, 0.47], P 〈 0.0001. The rate of leukopenia (OR = .31, 95%CI [0.20,0.47], P 〈 0.0001),thrombocytopenia (OR = 0.58, 95%CI [0.37, 0.91], P = 0.020), hemoglobin decline ((OR = 0.31, 95%CI [0.16,0.59], P = 0.0004) and incidence of gastrointestinal reactions (OR = 0.58,P 〈 0.05) could be reduced. Conclusion:Shenqi Fuzheng injection combined with GP chemotherapy in the treatment of advanced NSCLC obtainedsignificantly clinical efficacy. The quality of the literature incorporated is low, the conclusion requires high-qualityresearch to further prove. 展开更多
关键词 Shenqi Fuzheng GP chemotherapy Advanced non - small cell lung cancer Meta analysis
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Short lessons in basic life support improve self-assurance in performing cardiopulmonary resuscitation 被引量:7
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作者 Mario Kobras Sascha Langewand +2 位作者 Christina Murr Christiane Neu Jeannette Schmid 《World Journal of Emergency Medicine》 CAS 2016年第4期255-262,共8页
BACKGROUND:There are several reasons why resuscitation measures may lead to inferior results:difficulties in team building,delayed realization of the emergency and interruption of chest compression.This study investig... BACKGROUND:There are several reasons why resuscitation measures may lead to inferior results:difficulties in team building,delayed realization of the emergency and interruption of chest compression.This study investigated the outcome of a new form of in-hospital cardiopulmonary resuscitation(CPR) training with special focus on changes in self-assurance of potential helpers when faced with emergency situations.METHODS:Following a 12-month period of CPR training,questionnaires were distributed to participants and non-participants.Those non-participants who intended to undergo the training at a later date served as control group.RESULTS:The study showed that participants experienced a significant improvement in selfassurance,compared with their remembered self-assurance before the training.Their self-assurance also was significantly greater than that of the control group of non-participants.CONCLUSION:Short lessons in CPR have an impact on the self-assurance of medical and non-medical personnel. 展开更多
关键词 Basic life support Simulation training non-technical skills Cardiopulmonary resuscitation
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