Masked data are the system failure data when exact component causing system failure might be unknown.In this paper,the mathematical description of general masked data was presented in software reliability engineering....Masked data are the system failure data when exact component causing system failure might be unknown.In this paper,the mathematical description of general masked data was presented in software reliability engineering.Furthermore,a general maskedbased additive non-homogeneous Poisson process(NHPP) model was considered to analyze component reliability.However,the problem of masked-based additive model lies in the difficulty of estimating parameters.The maximum likelihood estimation procedure was derived to estimate parameters.Finally,a numerical example was given to illustrate the applicability of proposed model,and the immune particle swarm optimization(IPSO) algorithm was used in maximize log-likelihood function.展开更多
The outbreak of coronavirus has led to an increase in the demand for facemasks globally. Unavailability of appropriate polypropylene non-woven fabrics face masks as a result of inadequate supply to satisfy the growing...The outbreak of coronavirus has led to an increase in the demand for facemasks globally. Unavailability of appropriate polypropylene non-woven fabrics face masks as a result of inadequate supply to satisfy the growing population has brought about the manufacturing of locally fabrics masks to augment or substitute standard medical class facemasks. The study aims at analyzing airflow of these locally manufactured fabrics to determine possible means of transmitting the virus as well as establish comfort of the user of these masks. Standard polypropylene non-woven, woven and knitted fabrics were considered for the study. Air permeability test was conducted on these fabrics using Frazier Air permeability tester. Depending on the property significant variation in the textile fabrics, polypropylene non-woven is widely accepted for facial masks. Nevertheless, this study illustrates that woven and knitted fabrics have more open structures, which allow a high rate of air penetration and so may require two or three layers to prevent antimicrobial or antiviral potential.展开更多
Background: Cardiothoracic surgery is a common cause of acute respiratory failure and is associated with increased morbidity and mortality. We aimed to compare the outcomes of open heart surgery patients treated using...Background: Cardiothoracic surgery is a common cause of acute respiratory failure and is associated with increased morbidity and mortality. We aimed to compare the outcomes of open heart surgery patients treated using oxygen delivery devices with patients who receive NIV as a first-line therapy for hypoxemic respiratory failure. Materials and Methods: 40 patients who developed acute hypoxemic respiratory failure after open heart surgery and admitted to cardiothoracic ICU 20 patients received NIV and 20 patient received oxygen by venture mask. For all patients the following measurements were performed before and after CPAP AND Venture use: CBC, blood urea, serum creatinine body temperature, chest X-ray, Arterial blood gases (arterial pH, sodium bicarbonate, pcO2, SpO2 and PaO2-to-FiO2 ratio). Results: Mean PO2 and SO2 have increased after using of both venture and Cpap, increase in both PCO2 and HCO3 levels after using Venturi mask, CPAP mask was superior to venturi mask in avoiding the need of intubation, decreasing The ICU stay median length and also median length of hospitalization, all were lower in CPAP group than venture group. Also the mortality rate was lower in CPAP group than the venturi group. Conclusion: Using CPAP mask in severe AHRF following open heart surgery can avoid intubation, decreases the levels of tachypnea and arterial hypoxemia, decreases ICU stay, the length of hospitalization and also decreases the mortality rate compared with patients receiving high-concentration oxygen therapy with venture mask.展开更多
Using the air plasma ignition technique, physicochemical process of burning can be accelerated; concentration limit ofretrofires both can be extended; reliability of retrofires and stability of burning can be improved...Using the air plasma ignition technique, physicochemical process of burning can be accelerated; concentration limit ofretrofires both can be extended; reliability of retrofires and stability of burning can be improved. In this paper, using internalequivalent heat area in place of electric are that created Ohm heat, the flow fields of thermodynamic equilibrium chemistry con-gealment and chemistry non-equilibrium in the plasma generator were simulated. The influences of the inlet prerotation angleof air, the inlet total pressure of air and the airflow compression angle of spray nozzle on the temperature on the surface of elec-展开更多
The paper deals with the fluid field of web forming in wet-laid non-woven production.The influence of the turbulent flow on blending fiber and occluded fluid produced in pulp flow has been discussed in theory and prac...The paper deals with the fluid field of web forming in wet-laid non-woven production.The influence of the turbulent flow on blending fiber and occluded fluid produced in pulp flow has been discussed in theory and practice.The suitable use of the imported velocity of pulp is very important in producing wet-laid products of good quality.展开更多
Increasing evidence indicates that aberrant expressions of some microRNAs are associated with cancer progression.However,the roles and biological mechanisms of miRNA-16-5p in human non-small cell lung cancer(NSCLC)are...Increasing evidence indicates that aberrant expressions of some microRNAs are associated with cancer progression.However,the roles and biological mechanisms of miRNA-16-5p in human non-small cell lung cancer(NSCLC)are not to be well studied.Here,we validated that the expression of miR-16-5p was decreased significantly in NSCLC samples and cell lines.The correlation between the clinicopathological features of NSCLC and the miR-16-5p expression showed that the expression of miR-16-5p in non-small cell lung cancer was linked with the advanced TNM stage,positive lymph node metastasis,with short overall survival(OS).Also,a negative correlation between miR-16-5p and Fermitin family member 2(FERMT2)was observed,implying there may be a potential link about their regulation.The hypothesis was further confirmed by in-silico analysis and dual-luciferase reporter assay.Moreover,we demonstrated that the transfections of miR-16-5p mimics could alter some biological characteristics of NSCLC cells remarkably accomplished by the expression variance of FERMT2 in vitro and in vivo assays.Summarily,this study demonstrated that miR-16-5p,as a tumor suppression factor in NSCLC by targeting FERMT2,could serve as one promising biomarker in the prediction for NSCLC patients.展开更多
Multi-components sinusoidal engineering signals who are non-stationary signals were considered in this study since their separation and segmentations are of great interests in many engineering fields. In most cases, t...Multi-components sinusoidal engineering signals who are non-stationary signals were considered in this study since their separation and segmentations are of great interests in many engineering fields. In most cases, the segmentation of non-stationary or multi-component signals is conducted in time domain. In this paper, we explore the advantages of applying joint time-frequency (TF) distribution of the multi-component signals to identify their segments. The Spectrogram that is known as Short-Time Fourier Transform (STFT) will be used for obtaining the time-frequency kernel. Time marginal of the computed kernel is optimally used for the signal segmentation. In order to obtain the desirable segmentation, it requires first to improve time marginal of the kernel by using two-dimensional Wiener mask filter applied to the TF kernel to mitigate and suppress non-stationary noise or interference. Additionally, a proper choice of the sliding window and its overlaying has enhanced our scheme to capture the discontinuities corresponding to the boundaries of the candidate segments.展开更多
基金Technology Foundation of Guizhou Province,China(No.QianKeHeJZi[2015]2064)Scientific Research Foundation for Advanced Talents in Guizhou Institue of Technology and Science,China(No.XJGC20150106)Joint Foundation of Guizhou Province,China(No.QianKeHeLHZi[2015]7105)
文摘Masked data are the system failure data when exact component causing system failure might be unknown.In this paper,the mathematical description of general masked data was presented in software reliability engineering.Furthermore,a general maskedbased additive non-homogeneous Poisson process(NHPP) model was considered to analyze component reliability.However,the problem of masked-based additive model lies in the difficulty of estimating parameters.The maximum likelihood estimation procedure was derived to estimate parameters.Finally,a numerical example was given to illustrate the applicability of proposed model,and the immune particle swarm optimization(IPSO) algorithm was used in maximize log-likelihood function.
文摘The outbreak of coronavirus has led to an increase in the demand for facemasks globally. Unavailability of appropriate polypropylene non-woven fabrics face masks as a result of inadequate supply to satisfy the growing population has brought about the manufacturing of locally fabrics masks to augment or substitute standard medical class facemasks. The study aims at analyzing airflow of these locally manufactured fabrics to determine possible means of transmitting the virus as well as establish comfort of the user of these masks. Standard polypropylene non-woven, woven and knitted fabrics were considered for the study. Air permeability test was conducted on these fabrics using Frazier Air permeability tester. Depending on the property significant variation in the textile fabrics, polypropylene non-woven is widely accepted for facial masks. Nevertheless, this study illustrates that woven and knitted fabrics have more open structures, which allow a high rate of air penetration and so may require two or three layers to prevent antimicrobial or antiviral potential.
文摘Background: Cardiothoracic surgery is a common cause of acute respiratory failure and is associated with increased morbidity and mortality. We aimed to compare the outcomes of open heart surgery patients treated using oxygen delivery devices with patients who receive NIV as a first-line therapy for hypoxemic respiratory failure. Materials and Methods: 40 patients who developed acute hypoxemic respiratory failure after open heart surgery and admitted to cardiothoracic ICU 20 patients received NIV and 20 patient received oxygen by venture mask. For all patients the following measurements were performed before and after CPAP AND Venture use: CBC, blood urea, serum creatinine body temperature, chest X-ray, Arterial blood gases (arterial pH, sodium bicarbonate, pcO2, SpO2 and PaO2-to-FiO2 ratio). Results: Mean PO2 and SO2 have increased after using of both venture and Cpap, increase in both PCO2 and HCO3 levels after using Venturi mask, CPAP mask was superior to venturi mask in avoiding the need of intubation, decreasing The ICU stay median length and also median length of hospitalization, all were lower in CPAP group than venture group. Also the mortality rate was lower in CPAP group than the venturi group. Conclusion: Using CPAP mask in severe AHRF following open heart surgery can avoid intubation, decreases the levels of tachypnea and arterial hypoxemia, decreases ICU stay, the length of hospitalization and also decreases the mortality rate compared with patients receiving high-concentration oxygen therapy with venture mask.
文摘Using the air plasma ignition technique, physicochemical process of burning can be accelerated; concentration limit ofretrofires both can be extended; reliability of retrofires and stability of burning can be improved. In this paper, using internalequivalent heat area in place of electric are that created Ohm heat, the flow fields of thermodynamic equilibrium chemistry con-gealment and chemistry non-equilibrium in the plasma generator were simulated. The influences of the inlet prerotation angleof air, the inlet total pressure of air and the airflow compression angle of spray nozzle on the temperature on the surface of elec-
文摘The paper deals with the fluid field of web forming in wet-laid non-woven production.The influence of the turbulent flow on blending fiber and occluded fluid produced in pulp flow has been discussed in theory and practice.The suitable use of the imported velocity of pulp is very important in producing wet-laid products of good quality.
基金supported by grants from the National Natural Science Foundation of China(82041023 and 81773546)the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2020-I2M-1-001)+2 种基金the Chinese Academy of Medical Sciences Fund for Influenza Pandemic Response and Public Health Emergency System(2021P062QG008)the Bill&Melinda Gates Foundation(2021P057QG006)the Special Fund for Health Development Research of Beijing(2021-1G-3013)。
基金was supported by grants from the National Natural Science Foundation of China(No.81772281)the Shandong Province Taishan Scholar Project(No.ts201712067)+1 种基金the Major Research and Development Program of Shandong Province(No.2017GSF18124)the Natural Science Foundation of Shandong Province(No.ZR2020MH218).
文摘Increasing evidence indicates that aberrant expressions of some microRNAs are associated with cancer progression.However,the roles and biological mechanisms of miRNA-16-5p in human non-small cell lung cancer(NSCLC)are not to be well studied.Here,we validated that the expression of miR-16-5p was decreased significantly in NSCLC samples and cell lines.The correlation between the clinicopathological features of NSCLC and the miR-16-5p expression showed that the expression of miR-16-5p in non-small cell lung cancer was linked with the advanced TNM stage,positive lymph node metastasis,with short overall survival(OS).Also,a negative correlation between miR-16-5p and Fermitin family member 2(FERMT2)was observed,implying there may be a potential link about their regulation.The hypothesis was further confirmed by in-silico analysis and dual-luciferase reporter assay.Moreover,we demonstrated that the transfections of miR-16-5p mimics could alter some biological characteristics of NSCLC cells remarkably accomplished by the expression variance of FERMT2 in vitro and in vivo assays.Summarily,this study demonstrated that miR-16-5p,as a tumor suppression factor in NSCLC by targeting FERMT2,could serve as one promising biomarker in the prediction for NSCLC patients.
文摘Multi-components sinusoidal engineering signals who are non-stationary signals were considered in this study since their separation and segmentations are of great interests in many engineering fields. In most cases, the segmentation of non-stationary or multi-component signals is conducted in time domain. In this paper, we explore the advantages of applying joint time-frequency (TF) distribution of the multi-component signals to identify their segments. The Spectrogram that is known as Short-Time Fourier Transform (STFT) will be used for obtaining the time-frequency kernel. Time marginal of the computed kernel is optimally used for the signal segmentation. In order to obtain the desirable segmentation, it requires first to improve time marginal of the kernel by using two-dimensional Wiener mask filter applied to the TF kernel to mitigate and suppress non-stationary noise or interference. Additionally, a proper choice of the sliding window and its overlaying has enhanced our scheme to capture the discontinuities corresponding to the boundaries of the candidate segments.
