We ascertained the opinions of residents and faculty regarding technical skills decay during non-clinical training years and evaluated the effectiveness of a technical skills refresher curriculum (TSRC) offered to res...We ascertained the opinions of residents and faculty regarding technical skills decay during non-clinical training years and evaluated the effectiveness of a technical skills refresher curriculum (TSRC) offered to residents in the month prior to rejoining clinical training years. 32 faculty and 14 residents completed surveys which gleaned opinions regarding technical skills decay during non-clinical years. Six residents completed a TSRC during the month prior to rejoining clinical training. We compared clinical evaluations of the residents who completed the TSRC to residents who rejoined clinical training prior to the implementation of the curriculum. Surveys indicated that residents and faculty believe that non-clinical years have a slightly negative impact on technical skills and residents who completed dedicated research years would require up to 4 months for technical skills to return to the level of their non-research peers. Residents who completed the TSRC reported having significantly higher comfort levels with their technical skills after the curriculum展开更多
目的:探讨儿童非肾母细胞瘤性肾脏肿瘤的临床病理学特征、诊断及鉴别诊断。方法:回顾性分析24例儿童非肾母细胞瘤性肾脏肿瘤的临床、病理特点及免疫组化表型。结果:组织学:多囊性肾瘤(polycystic nephroma,CN)(4/24,16.7%),肿瘤由大小...目的:探讨儿童非肾母细胞瘤性肾脏肿瘤的临床病理学特征、诊断及鉴别诊断。方法:回顾性分析24例儿童非肾母细胞瘤性肾脏肿瘤的临床、病理特点及免疫组化表型。结果:组织学:多囊性肾瘤(polycystic nephroma,CN)(4/24,16.7%),肿瘤由大小不等的囊腔构成,囊内衬扁平或单层立方上皮。先天性中胚层细胞肾瘤(congenital mesoblastic nephroma,CMN)(6/24,25%),肿瘤主由束状或片状排列的肌纤维母细胞构成,类似婴儿型纤维肉瘤图像,并可见软骨结构。肾横纹肌样瘤(rhabdoid tumor of the kindey,RTK)(5/24,20.8%),肿瘤细胞呈巢状或片状排列,细胞类似肌纤维母细胞,可见包涵体。肾透明细胞肉瘤(clear cell sarcoma of the kidney,CCSK)(6/24,25%),肿瘤呈巢状或片状分布,细胞透亮,其间有网状血管间隔。Xp11.2易位/TFE3融合相关性肾癌(Xp11.2-translocation/TFE3 fusion-associated renal carcinoma)(3/24,12.5%),肿瘤呈囊状,囊内可见肿瘤细胞呈乳头状生长,胞浆透亮。免疫组化:以上肿瘤细胞均不表达WT-1、Desmin及Myogenin,除RTK以外均表达InI-1。CN免疫组化无特殊。CMN肿瘤细胞表达SMA及Vimentin。CCSK肿瘤细胞高表达CyclinD1及Bcor。Xp11.2易位/TFE3融合相关性肾癌表达TFE3。结论:儿童非肾母细胞瘤性肾脏肿瘤临床不常见,术前临床诊断较为困难,误诊率较高,其治疗不尽相同,病理检查是鉴别诊断非肾母细胞瘤性肾脏肿瘤的最可靠方法。展开更多
文摘We ascertained the opinions of residents and faculty regarding technical skills decay during non-clinical training years and evaluated the effectiveness of a technical skills refresher curriculum (TSRC) offered to residents in the month prior to rejoining clinical training years. 32 faculty and 14 residents completed surveys which gleaned opinions regarding technical skills decay during non-clinical years. Six residents completed a TSRC during the month prior to rejoining clinical training. We compared clinical evaluations of the residents who completed the TSRC to residents who rejoined clinical training prior to the implementation of the curriculum. Surveys indicated that residents and faculty believe that non-clinical years have a slightly negative impact on technical skills and residents who completed dedicated research years would require up to 4 months for technical skills to return to the level of their non-research peers. Residents who completed the TSRC reported having significantly higher comfort levels with their technical skills after the curriculum
文摘目的:探讨儿童非肾母细胞瘤性肾脏肿瘤的临床病理学特征、诊断及鉴别诊断。方法:回顾性分析24例儿童非肾母细胞瘤性肾脏肿瘤的临床、病理特点及免疫组化表型。结果:组织学:多囊性肾瘤(polycystic nephroma,CN)(4/24,16.7%),肿瘤由大小不等的囊腔构成,囊内衬扁平或单层立方上皮。先天性中胚层细胞肾瘤(congenital mesoblastic nephroma,CMN)(6/24,25%),肿瘤主由束状或片状排列的肌纤维母细胞构成,类似婴儿型纤维肉瘤图像,并可见软骨结构。肾横纹肌样瘤(rhabdoid tumor of the kindey,RTK)(5/24,20.8%),肿瘤细胞呈巢状或片状排列,细胞类似肌纤维母细胞,可见包涵体。肾透明细胞肉瘤(clear cell sarcoma of the kidney,CCSK)(6/24,25%),肿瘤呈巢状或片状分布,细胞透亮,其间有网状血管间隔。Xp11.2易位/TFE3融合相关性肾癌(Xp11.2-translocation/TFE3 fusion-associated renal carcinoma)(3/24,12.5%),肿瘤呈囊状,囊内可见肿瘤细胞呈乳头状生长,胞浆透亮。免疫组化:以上肿瘤细胞均不表达WT-1、Desmin及Myogenin,除RTK以外均表达InI-1。CN免疫组化无特殊。CMN肿瘤细胞表达SMA及Vimentin。CCSK肿瘤细胞高表达CyclinD1及Bcor。Xp11.2易位/TFE3融合相关性肾癌表达TFE3。结论:儿童非肾母细胞瘤性肾脏肿瘤临床不常见,术前临床诊断较为困难,误诊率较高,其治疗不尽相同,病理检查是鉴别诊断非肾母细胞瘤性肾脏肿瘤的最可靠方法。
