AIM:To access the agreement of intraocular pressure(IOP)values obtained from biomechanically corrected tonometer[Corvis ST(CST)],non-contact tonometer(NCT),and Goldmann applanation tonometer(GAT)in children with NCT m...AIM:To access the agreement of intraocular pressure(IOP)values obtained from biomechanically corrected tonometer[Corvis ST(CST)],non-contact tonometer(NCT),and Goldmann applanation tonometer(GAT)in children with NCT measured-IOP(NCT-IOP)values of 22 mm Hg or more,and related factors.METHODS:A total of 51 eyes with NCT-IOP≥22 mm Hg in children aged 7 to 14y were examined and IOP was measured by CST,NCT,and GAT.Based on GAT measured IOP(GAT-IOP),ocular hypertension(OHT)group(≥22 mm Hg,24 eyes)and the non-OHT group(<22 mm Hg,27 eyes)were defined.We compared the agreement of the three measurements,i.e.,CST measured IOP(CST-IOP),GAT-IOP,and NCT-IOP,and further analyzed the correlation between the differences in tonometry readings,central corneal thickness(CCT),axial length(AL),optic disc rim volume,and age.RESULTS:Compared with the OHT group,thicker CCT,larger rim volume,and higher differences between NCTIOP and GAT-IOP,were found in the non-OHT group.The differences between CST-IOP and GAT-IOP were lower than the differences between NCT-IOP and GAT-IOP in both groups.The mean differences in CST-IOP and GAT-IOP were 1.26 mm Hg(95%limit of agreement ranged from 0.1 to 2.41 mm Hg,OHT group)and 1.20 mm Hg(95%limit of agreement ranged from-0.5 to 3.00 mm Hg,non-OHT group),and the mean differences in NCT and GAT were 3.90 mm Hg(95%limit of agreement ranged from-0.19 to 9.70 mm Hg,OHT group)and 6.00 mm Hg(95%limit of agreement ranged from 1.50 to 10.50 mm Hg,non-OHT group).The differences between CST-IOP and GAT-IOP were not related to CCT,age,and AL in both groups;while the differences between NCT-IOP and GAT-IOP were related to CCT in the OHT group(r=0.93,P<0.001)and to CCT and AL in the non-OHT group(r=0.66,P<0.001,r=-0.81,P<0.001).CONCLUSION:The accuracy of NCT in the diagnosis of pediatric OHT is low.The agreement of CST-IOP and GATIOP was significantly higher in children with and without OHT than in those with NCT-IOP and GAT-IOP.Therefore,CST can be used as a good alternative for IOP measurement in children.The impacts of CCT and AL on NCT measurement need to be fully considered when managing childhood IOP.展开更多
AIM： To explore the relationship between different parameters of Ocular Response Analyzer（ORA） and Corvis ST（CST） in a sample of healthy Iranian school-aged children and the relationship between parameters of the...AIM： To explore the relationship between different parameters of Ocular Response Analyzer（ORA） and Corvis ST（CST） in a sample of healthy Iranian school-aged children and the relationship between parameters of these 2 instruments against intraocular pressure（IOP）, measured by the Goldmann applanation tonometer（GAT-IOP）, age and gender, and find possible correlation between ORA and CST with GAT.METHODS： This cross-sectional study included 90 healthy children. A general interview and complete eye examination were performed. Following successful GATIOP measurement, ORA and CST were conducted. The CST parameters were A 1/2 length（A1 L, A2 L）, A 1/2 velocity（A1 V, A2 V）, highest concavity deformation amplitude（HCDA）, radius of curvature（Ro C）, peak distance（PD）, central corneal thickness（CCT） and IOP. The ORA parameters were corneal hysteresis（CH）, corneal resistance factor（CRF）, Goldmann-correlated IOP（IOP-G） and corneal compensated IOP（IOP-CC）. Extracted data was analyzed using the Statistical Package for Social Science software.RESULTS： Totally 39 males with age of 9.08±1.60（6-12）y and 51 females with age of 8.96±1.55（6-13）y were included. Many CST parameters were significantly correlated with CH, CRF, IOP-G and IOP-CC. Some CST parameters had a significant correlation with GAT-IOP, including IOP-CST in both eyes and HCDA, A2 L, PD, and RoC in the left eye, but none with age, except A2 L in the right eye. The CRF measurement showed a significant correlation with GAT-IOP in both eyes and CH in the right eye, yet, none with age. Among all CST and ORA parameters, CCT-CST in both eyes and A1 L in right eye had a significant correlation with gender, although this was a negligible negative correlation. Comparison of mean IOP values by different devices showed a significantly highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Also, IOP-G versus IOP-CST significantly had the lowest IOP overestimation among others. Overall, either low positive correlation or negligible correlation was found between IOP measurements by 3 instruments.CONCLUSION： The study finds the highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Overall, either low positive correlation or negligible correlation is found between IOP measurements by the 3 instruments.展开更多
Background:This study investigated the agreement between a new rebound tonometer,IC200,and IcarePRO and Goldmann applanation tonometry(GAT).Methods:This was a prospective cross-sectional study.We measured the intraocu...Background:This study investigated the agreement between a new rebound tonometer,IC200,and IcarePRO and Goldmann applanation tonometry(GAT).Methods:This was a prospective cross-sectional study.We measured the intraocular pressure(IOP)in 145 eyes of 145 glaucoma patients in the sitting position using GAT,IcarePRO,and IC200.IcarePRO and IC200 measurements were also obtained in the supine position.IC200 measurement was performed using two modes:single six(IC200-single)and automatic(IC200-continuous)six-measurements mode.Results:All tonometers provided high reproducibility in both positions(all intraclass correlation coefficients>0.90),although it was highest with GAT,followed by IC200-continuous and IC200-single and then IcarePRO.In the sitting position,the mean(±SD)IOPs of GAT,IcarePRO,IC200-single,and IC200-continuous were 14.5±2.9 mmHg,13.3±3.2 mmHg,11.6±3.2 mmHg,and 11.5±3.2 mmHg,respectively.IOPs measured with IcarePRO or IC200 were significantly lower than those with GAT,particularly in patients with low IOP.IOPs measured with all tonometers were significantly elevated in the supine position as compared with the sitting position,but this difference was significantly greater with IC200-single and IC200-continuous compared with IcarePRO.IOP elevation was significant in eyes without bleb versus those with bleb,but this finding was not observed when IOP was measured with IcarePRO.The IOPs of the single and continuous modes of IC200 were interchangeable in both positions.Conclusions:GAT,IcarePRO,and IC200 had sufficiently high reproducibility,but measurements with IcarePRO may not be accurate in the supine position.Elevation of IOP in the supine position,especially in eyes with bleb,was more sensitively captured with IC200 than with IcarePRO.展开更多
AIM: To evaluate the impact of central corneal thickness(CCT) and corneal curvature on intraocular pressure(IOP) measurements performed by three different tonometers. METHODS: IOP in 132 healthy eyes of 66 participant...AIM: To evaluate the impact of central corneal thickness(CCT) and corneal curvature on intraocular pressure(IOP) measurements performed by three different tonometers. METHODS: IOP in 132 healthy eyes of 66 participants was measured using three different tonometry techniques: Goldmann applanation tonometer(GAT), Pascal dynamic contour tonometer(DCT), and ICare rebound tonometer(RT). CCT and corneal curvature were assessed. RESULTS: In healthy eyes, DCT presents significantly higher values of IOP than GAT(17.34±3.69 and 15.27±4.06 mm Hg, P<0.0001). RT measurements are significantly lower than GAT(13.56±4.33 mm Hg, P<0.0001). Compared with GAT, DCT presented on average 2.51 mm Hg higher values in eyes with CCT<600 μm and 0.99 mm Hg higher results in eyes with CCT≥600 μm. The RT results were lower on average by 1.61 and 1.95 mm Hg than those obtained by GAT, respectively. Positive correlations between CCT in eyes with CCT<600 μm were detected for all IOP measurement techniques, whereas a similar relationship was not observed in eyes with thicker corneas. A correlation between IOP values and keratometry in the group with CCT<600 μm was not detected with any of the tonometry methods. In thicker corneas, a positive correlation was found for GAT and mean keratometry values(R=0.369, P=0.005). CONCLUSION: The same method should always be chosen for routine IOP control, and measurements obtained by different methods cannot be compared. All analysed tonometry methods are dependent on CCT;thus, CCT should be taken into consideration for both diagnostics and monitoring.展开更多
目的探讨非接触眼压计在青光眼患者眼压测量中的临床应用效果。方法本次研究起止时间为2019年9月至2021年3月,选取200例青光眼患者(310眼)作为观察对象,依次对患者进行非接触眼压计、Goldmann眼压计眼压测量,比较不同眼压测量方案的临...目的探讨非接触眼压计在青光眼患者眼压测量中的临床应用效果。方法本次研究起止时间为2019年9月至2021年3月,选取200例青光眼患者(310眼)作为观察对象,依次对患者进行非接触眼压计、Goldmann眼压计眼压测量,比较不同眼压测量方案的临床效果以及青光眼的检出率。结果非接触眼压计眼压测量值范围在6~50 mm Hg,Goldmann眼压计眼压测量值范围在6~58 mm Hg;对于眼压≤21 mm Hg的青光眼患者,非接触眼压计与Goldmann眼压计在眼压测量结果差异无统计学意义(P>0.05);对于眼压>21 mm Hg的青光眼患者,非接触眼压计眼压测量值低于Goldmann眼压计眼压测量值(P<0.05)。应用非接触眼压计检测出293例青光眼,检出率为97.7%,应用Goldmann眼压计检出211例青光眼,检出率为68.1%,差异有统计学意义(P<0.05)。结论针对青光眼患者而言,非接触眼压计眼压测量具有操作简单、安全无创、不良反应少的优势,适用于大范围青光眼患者的筛查。对于处于临界眼压值的青光眼患者,推荐使用Goldmann眼压计眼压测量,以提高检出率,及时发现病理性眼压指标,为患者的治疗提供数据参考。展开更多
基金Supported by Medical Science Research Project of Hebei Province in 2023(No.20231818).
文摘AIM:To access the agreement of intraocular pressure(IOP)values obtained from biomechanically corrected tonometer[Corvis ST(CST)],non-contact tonometer(NCT),and Goldmann applanation tonometer(GAT)in children with NCT measured-IOP(NCT-IOP)values of 22 mm Hg or more,and related factors.METHODS:A total of 51 eyes with NCT-IOP≥22 mm Hg in children aged 7 to 14y were examined and IOP was measured by CST,NCT,and GAT.Based on GAT measured IOP(GAT-IOP),ocular hypertension(OHT)group(≥22 mm Hg,24 eyes)and the non-OHT group(<22 mm Hg,27 eyes)were defined.We compared the agreement of the three measurements,i.e.,CST measured IOP(CST-IOP),GAT-IOP,and NCT-IOP,and further analyzed the correlation between the differences in tonometry readings,central corneal thickness(CCT),axial length(AL),optic disc rim volume,and age.RESULTS:Compared with the OHT group,thicker CCT,larger rim volume,and higher differences between NCTIOP and GAT-IOP,were found in the non-OHT group.The differences between CST-IOP and GAT-IOP were lower than the differences between NCT-IOP and GAT-IOP in both groups.The mean differences in CST-IOP and GAT-IOP were 1.26 mm Hg(95%limit of agreement ranged from 0.1 to 2.41 mm Hg,OHT group)and 1.20 mm Hg(95%limit of agreement ranged from-0.5 to 3.00 mm Hg,non-OHT group),and the mean differences in NCT and GAT were 3.90 mm Hg(95%limit of agreement ranged from-0.19 to 9.70 mm Hg,OHT group)and 6.00 mm Hg(95%limit of agreement ranged from 1.50 to 10.50 mm Hg,non-OHT group).The differences between CST-IOP and GAT-IOP were not related to CCT,age,and AL in both groups;while the differences between NCT-IOP and GAT-IOP were related to CCT in the OHT group(r=0.93,P<0.001)and to CCT and AL in the non-OHT group(r=0.66,P<0.001,r=-0.81,P<0.001).CONCLUSION:The accuracy of NCT in the diagnosis of pediatric OHT is low.The agreement of CST-IOP and GATIOP was significantly higher in children with and without OHT than in those with NCT-IOP and GAT-IOP.Therefore,CST can be used as a good alternative for IOP measurement in children.The impacts of CCT and AL on NCT measurement need to be fully considered when managing childhood IOP.
基金Supported by deputy dean in research of School of Medicine according to study project and deputy vice chancellor of Shiraz University of Medical Sciences
文摘AIM： To explore the relationship between different parameters of Ocular Response Analyzer（ORA） and Corvis ST（CST） in a sample of healthy Iranian school-aged children and the relationship between parameters of these 2 instruments against intraocular pressure（IOP）, measured by the Goldmann applanation tonometer（GAT-IOP）, age and gender, and find possible correlation between ORA and CST with GAT.METHODS： This cross-sectional study included 90 healthy children. A general interview and complete eye examination were performed. Following successful GATIOP measurement, ORA and CST were conducted. The CST parameters were A 1/2 length（A1 L, A2 L）, A 1/2 velocity（A1 V, A2 V）, highest concavity deformation amplitude（HCDA）, radius of curvature（Ro C）, peak distance（PD）, central corneal thickness（CCT） and IOP. The ORA parameters were corneal hysteresis（CH）, corneal resistance factor（CRF）, Goldmann-correlated IOP（IOP-G） and corneal compensated IOP（IOP-CC）. Extracted data was analyzed using the Statistical Package for Social Science software.RESULTS： Totally 39 males with age of 9.08±1.60（6-12）y and 51 females with age of 8.96±1.55（6-13）y were included. Many CST parameters were significantly correlated with CH, CRF, IOP-G and IOP-CC. Some CST parameters had a significant correlation with GAT-IOP, including IOP-CST in both eyes and HCDA, A2 L, PD, and RoC in the left eye, but none with age, except A2 L in the right eye. The CRF measurement showed a significant correlation with GAT-IOP in both eyes and CH in the right eye, yet, none with age. Among all CST and ORA parameters, CCT-CST in both eyes and A1 L in right eye had a significant correlation with gender, although this was a negligible negative correlation. Comparison of mean IOP values by different devices showed a significantly highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Also, IOP-G versus IOP-CST significantly had the lowest IOP overestimation among others. Overall, either low positive correlation or negligible correlation was found between IOP measurements by 3 instruments.CONCLUSION： The study finds the highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Overall, either low positive correlation or negligible correlation is found between IOP measurements by the 3 instruments.
文摘Background:This study investigated the agreement between a new rebound tonometer,IC200,and IcarePRO and Goldmann applanation tonometry(GAT).Methods:This was a prospective cross-sectional study.We measured the intraocular pressure(IOP)in 145 eyes of 145 glaucoma patients in the sitting position using GAT,IcarePRO,and IC200.IcarePRO and IC200 measurements were also obtained in the supine position.IC200 measurement was performed using two modes:single six(IC200-single)and automatic(IC200-continuous)six-measurements mode.Results:All tonometers provided high reproducibility in both positions(all intraclass correlation coefficients>0.90),although it was highest with GAT,followed by IC200-continuous and IC200-single and then IcarePRO.In the sitting position,the mean(±SD)IOPs of GAT,IcarePRO,IC200-single,and IC200-continuous were 14.5±2.9 mmHg,13.3±3.2 mmHg,11.6±3.2 mmHg,and 11.5±3.2 mmHg,respectively.IOPs measured with IcarePRO or IC200 were significantly lower than those with GAT,particularly in patients with low IOP.IOPs measured with all tonometers were significantly elevated in the supine position as compared with the sitting position,but this difference was significantly greater with IC200-single and IC200-continuous compared with IcarePRO.IOP elevation was significant in eyes without bleb versus those with bleb,but this finding was not observed when IOP was measured with IcarePRO.The IOPs of the single and continuous modes of IC200 were interchangeable in both positions.Conclusions:GAT,IcarePRO,and IC200 had sufficiently high reproducibility,but measurements with IcarePRO may not be accurate in the supine position.Elevation of IOP in the supine position,especially in eyes with bleb,was more sensitively captured with IC200 than with IcarePRO.
文摘AIM: To evaluate the impact of central corneal thickness(CCT) and corneal curvature on intraocular pressure(IOP) measurements performed by three different tonometers. METHODS: IOP in 132 healthy eyes of 66 participants was measured using three different tonometry techniques: Goldmann applanation tonometer(GAT), Pascal dynamic contour tonometer(DCT), and ICare rebound tonometer(RT). CCT and corneal curvature were assessed. RESULTS: In healthy eyes, DCT presents significantly higher values of IOP than GAT(17.34±3.69 and 15.27±4.06 mm Hg, P<0.0001). RT measurements are significantly lower than GAT(13.56±4.33 mm Hg, P<0.0001). Compared with GAT, DCT presented on average 2.51 mm Hg higher values in eyes with CCT<600 μm and 0.99 mm Hg higher results in eyes with CCT≥600 μm. The RT results were lower on average by 1.61 and 1.95 mm Hg than those obtained by GAT, respectively. Positive correlations between CCT in eyes with CCT<600 μm were detected for all IOP measurement techniques, whereas a similar relationship was not observed in eyes with thicker corneas. A correlation between IOP values and keratometry in the group with CCT<600 μm was not detected with any of the tonometry methods. In thicker corneas, a positive correlation was found for GAT and mean keratometry values(R=0.369, P=0.005). CONCLUSION: The same method should always be chosen for routine IOP control, and measurements obtained by different methods cannot be compared. All analysed tonometry methods are dependent on CCT;thus, CCT should be taken into consideration for both diagnostics and monitoring.
文摘目的探讨非接触眼压计在青光眼患者眼压测量中的临床应用效果。方法本次研究起止时间为2019年9月至2021年3月,选取200例青光眼患者(310眼)作为观察对象,依次对患者进行非接触眼压计、Goldmann眼压计眼压测量,比较不同眼压测量方案的临床效果以及青光眼的检出率。结果非接触眼压计眼压测量值范围在6~50 mm Hg,Goldmann眼压计眼压测量值范围在6~58 mm Hg;对于眼压≤21 mm Hg的青光眼患者,非接触眼压计与Goldmann眼压计在眼压测量结果差异无统计学意义(P>0.05);对于眼压>21 mm Hg的青光眼患者,非接触眼压计眼压测量值低于Goldmann眼压计眼压测量值(P<0.05)。应用非接触眼压计检测出293例青光眼,检出率为97.7%,应用Goldmann眼压计检出211例青光眼,检出率为68.1%,差异有统计学意义(P<0.05)。结论针对青光眼患者而言,非接触眼压计眼压测量具有操作简单、安全无创、不良反应少的优势,适用于大范围青光眼患者的筛查。对于处于临界眼压值的青光眼患者,推荐使用Goldmann眼压计眼压测量,以提高检出率,及时发现病理性眼压指标,为患者的治疗提供数据参考。
