A class of singularly perturbed initial boundary value problems for the reaction diffusion equations in a part of domain are considered. Using the operator theory the asymptotic behavior of solution for the problems i...A class of singularly perturbed initial boundary value problems for the reaction diffusion equations in a part of domain are considered. Using the operator theory the asymptotic behavior of solution for the problems is studied.展开更多
The problems of the nonlocal boundary conditions for the singularly perturbed reaction diffusion systems are considered. Under suitable conditions, using the comparison theorem the asymptotic behavior of solution for ...The problems of the nonlocal boundary conditions for the singularly perturbed reaction diffusion systems are considered. Under suitable conditions, using the comparison theorem the asymptotic behavior of solution for the initial boundary value problems are studied.展开更多
In this paper,we consider a Cauchy problem of the time fractional diffusion equation(TFDE)in x∈[0,L].This problem is ubiquitous in science and engineering applications.The illposedness of the Cauchy problem is explai...In this paper,we consider a Cauchy problem of the time fractional diffusion equation(TFDE)in x∈[0,L].This problem is ubiquitous in science and engineering applications.The illposedness of the Cauchy problem is explained by its solution in frequency domain.Furthermore,the problem is formulated into a minimization problem with a modified Tikhonov regularization method.The gradient of the regularization functional based on an adjoint problem is deduced and the standard conjugate gradient method is presented for solving the minimization problem.The error estimates for the regularized solutions are obtained under Hp norm priori bound assumptions.Finally,numerical examples illustrate the effectiveness of the proposed method.展开更多
Aim The purpose of this study was to develop a mathe-matical model to quantitatively describe the passive trans-port of macromolecules within dental biofilms. Methodology Fluorescently labeled dextrans with different ...Aim The purpose of this study was to develop a mathe-matical model to quantitatively describe the passive trans-port of macromolecules within dental biofilms. Methodology Fluorescently labeled dextrans with different molecular mass (3 kD,10 kD,40 kD,70 kD,2 000 kD) were used as a series of diffusion probes. Streptococcus mutans,Streptococcus sanguinis,Actinomyces naeslundii and Fusobacterium nucleatum were used as inocula for biofilm formation. The diffusion processes of different probes through the in vitro biofilm were recorded with a confocal laser microscope. Results Mathematical function of biofilm penetration was constructed on the basis of the inverse problem method. Based on this function,not only the relationship between average concentration of steady-state and molecule weights can be analyzed,but also that between penetrative time and molecule weights. Conclusion This can be used to predict the effective concentration and the penetrative time of anti-biofilm medicines that can diffuse through oral biofilm. Further-more,an improved model for large molecule is proposed by considering the exchange time at the upper boundary of the dental biofilm.展开更多
A class of singularly perturbed initial boundary value problems for the reaction diffusion equations in a part of domain are considered. Using the operator theory the asymptotic behavior of solution for the problems i...A class of singularly perturbed initial boundary value problems for the reaction diffusion equations in a part of domain are considered. Using the operator theory the asymptotic behavior of solution for the problems is studied.展开更多
This paper aims to present a new streamline diffusion method with low order rectangular Bernardi-Raugel elements to solve the generalized Oseen equations. With the help of the Bramble-Hilbert lemma, the optimal errors...This paper aims to present a new streamline diffusion method with low order rectangular Bernardi-Raugel elements to solve the generalized Oseen equations. With the help of the Bramble-Hilbert lemma, the optimal errors of the velocity and pressure are estimated, which are independent of the considered parameter e. With an interpolation postprocessing approach, the superconvergent error of the pressure is obtained. Finally, a numerical experiment is carried out to confirm the theoretical results.展开更多
The transport behavior of free boundary value problems for a class ofgeneralized diffusion equations was studied. Suitable similarity transformations were used toconvert the problems into a class of singular nonlinear...The transport behavior of free boundary value problems for a class ofgeneralized diffusion equations was studied. Suitable similarity transformations were used toconvert the problems into a class of singular nonlinear two-point boundary value problems andsimilarity solutions were numerical presented for different representations of heat conductionfunction, convection function, heat flux function, and power law parameters by utilizing theshooting technique. The results revealed the flux transfer mechanism and the character as well asthe effects of parameters on the solutions.展开更多
A mathematical model of CE reaction schemes under first or pseudo-first order conditions with different diffusion coefficients at a spherical electrode under non-steady-state conditions is described. The model is base...A mathematical model of CE reaction schemes under first or pseudo-first order conditions with different diffusion coefficients at a spherical electrode under non-steady-state conditions is described. The model is based on non-stationary diffusion equation containing a non-linear reaction term. This paper presents the complex numerical method (Homotopy perturbation method) to solve the system of non-linear differential equation that describes the homogeneous processes coupled to electrode reaction. In this paper the approximate analytical expressions of the non-steady-state concentrations and current at spherical electrodes for homogeneous reactions mechanisms are derived for all values of the reaction diffusion parameters. These approximate results are compared with the available analytical results and are found to be in good agreement.展开更多
Studies of problems involving physical anisotropy are applied in sciences and engineering,for instance,when the thermal conductivity depends on the direction.In this study,the multigrid method was used in order to acc...Studies of problems involving physical anisotropy are applied in sciences and engineering,for instance,when the thermal conductivity depends on the direction.In this study,the multigrid method was used in order to accelerate the convergence of the iterative methods used to solve this type of problem.The asymptotic convergence factor of the multigrid was determined empirically(computer aided)and also by employing local Fourier analysis(LFA).The mathematical model studied was the 2D anisotropic diffusion equation,in whichε>0 was the coefficient of a nisotropy.The equation was discretized by the Finite Difference Method(FDM)and Central Differencing Scheme(CDS).Correction Scheme(CS),pointwise Gauss-Seidel smoothers(Lexicographic and Red-Black ordering),and line Gauss-Seidel smoothers(Lexicographic and Zebra ordering)in x and y directions were used for building the multigrid.The best asymptotic convergence factor was obtained by the Gauss-Seidel method in the direction x for 0<ε<<1 and in the direction y forε>>1.In this sense,an xy-zebra-GS smoother was proposed,which proved to be efficient and robust for the different anisotropy coefficients.Moreover,the convergence factors calculated empirically and by LFA are in agreement.展开更多
In this paper,we investigate a streamline diffusion finite element approxi- mation scheme for the constrained optimal control problem governed by linear con- vection dominated diffusion equations.We prove the existenc...In this paper,we investigate a streamline diffusion finite element approxi- mation scheme for the constrained optimal control problem governed by linear con- vection dominated diffusion equations.We prove the existence and uniqueness of the discretized scheme.Then a priori and a posteriori error estimates are derived for the state,the co-state and the control.Three numerical examples are presented to illustrate our theoretical results.展开更多
With the aid of a nonlinear transformation, a class of nonlinear convection-diffusion PDE in one space dimension is converted into a linear one, the unique solution of a nonlinear boundary-initial value problem for th...With the aid of a nonlinear transformation, a class of nonlinear convection-diffusion PDE in one space dimension is converted into a linear one, the unique solution of a nonlinear boundary-initial value problem for the nonlinear PDE can be exactly expressed by the nonlinear transformation, and several illustrative examples are given.展开更多
A streamline upwind finite element method using 6-node triangular element is presented. The method is applied to the convection term of the governing transport equation directly along local streamlines. Several convec...A streamline upwind finite element method using 6-node triangular element is presented. The method is applied to the convection term of the governing transport equation directly along local streamlines. Several convective-diffusion examples are used to evaluate efficiency of the method. Results show that the method is monotonic and does not produce any oscillation. In addition, an adaptive meshing technique is combined with the method to further increase accuracy of the solution, and at the same time, to minimize computational time and computer memory requirement.展开更多
In this paper, we study the asymptotic behavior of the solutions to the initial boundary value problem for unipolar drift diffusion equations for semiconductors. Under the proper assumptions on doping profile and init...In this paper, we study the asymptotic behavior of the solutions to the initial boundary value problem for unipolar drift diffusion equations for semiconductors. Under the proper assumptions on doping profile and initial value, we prove that the smooth solutions to these evolutionary problems tend to the unique stationary solution exponentially as time tends to infinity.展开更多
The existence of a global minimizer for a variational problem arising in registration of diffusion tensor images is proved, which ensures that there is a regular spatial transformation for the registration of diffusio...The existence of a global minimizer for a variational problem arising in registration of diffusion tensor images is proved, which ensures that there is a regular spatial transformation for the registration of diffusion tensor images.展开更多
In this paper, the author analyzes the singularity of a boundary layer in a nonlinear diffusion problem. Results show when the limiting solution satisfies the boundary condition, there is no boundary singularity. Othe...In this paper, the author analyzes the singularity of a boundary layer in a nonlinear diffusion problem. Results show when the limiting solution satisfies the boundary condition, there is no boundary singularity. Otherwise, the boundary layer exists, and its thickness is proportional to epsilon(1/2), here epsilon is a small positive real parameter.展开更多
The singularly perturbed initial boudary value problem for the nonlocal reaction diffusion systems was considered. Using iteration method the comparison theorem was obtained. Introducing stretched variable the formal ...The singularly perturbed initial boudary value problem for the nonlocal reaction diffusion systems was considered. Using iteration method the comparison theorem was obtained. Introducing stretched variable the formal asymptotic solution was constructed. And the existence and its asymptotic behavior of solution for the problem were studied by using the method of the upper and lower solution.展开更多
An approximate analytical solution of moving boundary problem for diffusion release of drug from a cylinder polymeric matrix was obtained by use of refined integral method. The release kinetics has been analyzed for n...An approximate analytical solution of moving boundary problem for diffusion release of drug from a cylinder polymeric matrix was obtained by use of refined integral method. The release kinetics has been analyzed for non-erodible matrices with perfect sink condition. The formulas of the moving boundary and the fractional drug release were given. The moving boundary and the fractional drug release have been calculated at various drug loading levels, mid the calculated results were in good agreement with those of experiments. The comparison of the moving boundary in spherical, cylinder, planar matrices has been completed. An approximate formula for estimating the available release time was presented. These results are useful for the clinic experiments. This investigation provides a new theoretical tool for studying the diffusion release of drug from a cylinder polymeric matrix and designing the controlled released drug.展开更多
A finite volume element method is developed for analyzing unsteady scalar reaction-diffusion problems in two dimensions. The method combines the concepts that are employed in the finite volume and the finite element m...A finite volume element method is developed for analyzing unsteady scalar reaction-diffusion problems in two dimensions. The method combines the concepts that are employed in the finite volume and the finite element method together. The finite volume method is used to discretize the unsteady reaction-diffusion equation, while the finite element method is applied to estimate the gradient quantities at cell faces. Robustness and efficiency of the combined method have been evaluated on uniform rectangular grids by using available numerical solutions of the two-dimensional reaction-diffusion problems. The numerical solutions demonstrate that the combined method is stable and can provide accurate solution without spurious oscillation along the high-gradient boundary layers.展开更多
文摘A class of singularly perturbed initial boundary value problems for the reaction diffusion equations in a part of domain are considered. Using the operator theory the asymptotic behavior of solution for the problems is studied.
文摘The problems of the nonlocal boundary conditions for the singularly perturbed reaction diffusion systems are considered. Under suitable conditions, using the comparison theorem the asymptotic behavior of solution for the initial boundary value problems are studied.
基金Supported by the National Natural Science Foundation of China(Grant No.11471253 and No.11571311)
文摘In this paper,we consider a Cauchy problem of the time fractional diffusion equation(TFDE)in x∈[0,L].This problem is ubiquitous in science and engineering applications.The illposedness of the Cauchy problem is explained by its solution in frequency domain.Furthermore,the problem is formulated into a minimization problem with a modified Tikhonov regularization method.The gradient of the regularization functional based on an adjoint problem is deduced and the standard conjugate gradient method is presented for solving the minimization problem.The error estimates for the regularized solutions are obtained under Hp norm priori bound assumptions.Finally,numerical examples illustrate the effectiveness of the proposed method.
基金supported by a grant from the National Natural Science Foundation of China (NSFC) No. 81070826/30872886/30400497Sponsored by Shanghai Rising-Star Program No. 09QA1403700+1 种基金funded by Shanghai Leading Academic Discipline Project (Project Number: S30206)the Science and Technology Commission of Shanghai (08DZ2271100)
文摘Aim The purpose of this study was to develop a mathe-matical model to quantitatively describe the passive trans-port of macromolecules within dental biofilms. Methodology Fluorescently labeled dextrans with different molecular mass (3 kD,10 kD,40 kD,70 kD,2 000 kD) were used as a series of diffusion probes. Streptococcus mutans,Streptococcus sanguinis,Actinomyces naeslundii and Fusobacterium nucleatum were used as inocula for biofilm formation. The diffusion processes of different probes through the in vitro biofilm were recorded with a confocal laser microscope. Results Mathematical function of biofilm penetration was constructed on the basis of the inverse problem method. Based on this function,not only the relationship between average concentration of steady-state and molecule weights can be analyzed,but also that between penetrative time and molecule weights. Conclusion This can be used to predict the effective concentration and the penetrative time of anti-biofilm medicines that can diffuse through oral biofilm. Further-more,an improved model for large molecule is proposed by considering the exchange time at the upper boundary of the dental biofilm.
文摘A class of singularly perturbed initial boundary value problems for the reaction diffusion equations in a part of domain are considered. Using the operator theory the asymptotic behavior of solution for the problems is studied.
基金supported by the National Natural Science Foundation of China(Nos.11271340 and11671369)
文摘This paper aims to present a new streamline diffusion method with low order rectangular Bernardi-Raugel elements to solve the generalized Oseen equations. With the help of the Bramble-Hilbert lemma, the optimal errors of the velocity and pressure are estimated, which are independent of the considered parameter e. With an interpolation postprocessing approach, the superconvergent error of the pressure is obtained. Finally, a numerical experiment is carried out to confirm the theoretical results.
基金This work was financially supported by the Cross-Century Talents Projects of Educational Ministry of China and the 973 Key Item (No. G1998061510).]
文摘The transport behavior of free boundary value problems for a class ofgeneralized diffusion equations was studied. Suitable similarity transformations were used toconvert the problems into a class of singular nonlinear two-point boundary value problems andsimilarity solutions were numerical presented for different representations of heat conductionfunction, convection function, heat flux function, and power law parameters by utilizing theshooting technique. The results revealed the flux transfer mechanism and the character as well asthe effects of parameters on the solutions.
文摘A mathematical model of CE reaction schemes under first or pseudo-first order conditions with different diffusion coefficients at a spherical electrode under non-steady-state conditions is described. The model is based on non-stationary diffusion equation containing a non-linear reaction term. This paper presents the complex numerical method (Homotopy perturbation method) to solve the system of non-linear differential equation that describes the homogeneous processes coupled to electrode reaction. In this paper the approximate analytical expressions of the non-steady-state concentrations and current at spherical electrodes for homogeneous reactions mechanisms are derived for all values of the reaction diffusion parameters. These approximate results are compared with the available analytical results and are found to be in good agreement.
文摘Studies of problems involving physical anisotropy are applied in sciences and engineering,for instance,when the thermal conductivity depends on the direction.In this study,the multigrid method was used in order to accelerate the convergence of the iterative methods used to solve this type of problem.The asymptotic convergence factor of the multigrid was determined empirically(computer aided)and also by employing local Fourier analysis(LFA).The mathematical model studied was the 2D anisotropic diffusion equation,in whichε>0 was the coefficient of a nisotropy.The equation was discretized by the Finite Difference Method(FDM)and Central Differencing Scheme(CDS).Correction Scheme(CS),pointwise Gauss-Seidel smoothers(Lexicographic and Red-Black ordering),and line Gauss-Seidel smoothers(Lexicographic and Zebra ordering)in x and y directions were used for building the multigrid.The best asymptotic convergence factor was obtained by the Gauss-Seidel method in the direction x for 0<ε<<1 and in the direction y forε>>1.In this sense,an xy-zebra-GS smoother was proposed,which proved to be efficient and robust for the different anisotropy coefficients.Moreover,the convergence factors calculated empirically and by LFA are in agreement.
基金supported by the National Basic Research Program under the Grant 2005CB321701the National Natural Science Foundation of China under the Grants 60474027 and 10771211.
文摘In this paper,we investigate a streamline diffusion finite element approxi- mation scheme for the constrained optimal control problem governed by linear con- vection dominated diffusion equations.We prove the existence and uniqueness of the discretized scheme.Then a priori and a posteriori error estimates are derived for the state,the co-state and the control.Three numerical examples are presented to illustrate our theoretical results.
基金Natural Science Foundation of Gansu Province of China
文摘With the aid of a nonlinear transformation, a class of nonlinear convection-diffusion PDE in one space dimension is converted into a linear one, the unique solution of a nonlinear boundary-initial value problem for the nonlinear PDE can be exactly expressed by the nonlinear transformation, and several illustrative examples are given.
文摘A streamline upwind finite element method using 6-node triangular element is presented. The method is applied to the convection term of the governing transport equation directly along local streamlines. Several convective-diffusion examples are used to evaluate efficiency of the method. Results show that the method is monotonic and does not produce any oscillation. In addition, an adaptive meshing technique is combined with the method to further increase accuracy of the solution, and at the same time, to minimize computational time and computer memory requirement.
文摘In this paper, we study the asymptotic behavior of the solutions to the initial boundary value problem for unipolar drift diffusion equations for semiconductors. Under the proper assumptions on doping profile and initial value, we prove that the smooth solutions to these evolutionary problems tend to the unique stationary solution exponentially as time tends to infinity.
基金supported by NSFC under grant No.11471331partially supported by National Center for Mathematics and Interdisciplinary Sciences
文摘The existence of a global minimizer for a variational problem arising in registration of diffusion tensor images is proved, which ensures that there is a regular spatial transformation for the registration of diffusion tensor images.
文摘In this paper, the author analyzes the singularity of a boundary layer in a nonlinear diffusion problem. Results show when the limiting solution satisfies the boundary condition, there is no boundary singularity. Otherwise, the boundary layer exists, and its thickness is proportional to epsilon(1/2), here epsilon is a small positive real parameter.
文摘The singularly perturbed initial boudary value problem for the nonlocal reaction diffusion systems was considered. Using iteration method the comparison theorem was obtained. Introducing stretched variable the formal asymptotic solution was constructed. And the existence and its asymptotic behavior of solution for the problem were studied by using the method of the upper and lower solution.
文摘An approximate analytical solution of moving boundary problem for diffusion release of drug from a cylinder polymeric matrix was obtained by use of refined integral method. The release kinetics has been analyzed for non-erodible matrices with perfect sink condition. The formulas of the moving boundary and the fractional drug release were given. The moving boundary and the fractional drug release have been calculated at various drug loading levels, mid the calculated results were in good agreement with those of experiments. The comparison of the moving boundary in spherical, cylinder, planar matrices has been completed. An approximate formula for estimating the available release time was presented. These results are useful for the clinic experiments. This investigation provides a new theoretical tool for studying the diffusion release of drug from a cylinder polymeric matrix and designing the controlled released drug.
文摘A finite volume element method is developed for analyzing unsteady scalar reaction-diffusion problems in two dimensions. The method combines the concepts that are employed in the finite volume and the finite element method together. The finite volume method is used to discretize the unsteady reaction-diffusion equation, while the finite element method is applied to estimate the gradient quantities at cell faces. Robustness and efficiency of the combined method have been evaluated on uniform rectangular grids by using available numerical solutions of the two-dimensional reaction-diffusion problems. The numerical solutions demonstrate that the combined method is stable and can provide accurate solution without spurious oscillation along the high-gradient boundary layers.