期刊文献+
共找到7,703篇文章
< 1 2 250 >
每页显示 20 50 100
Operating procedures of traditional Chinese medicine breast massage
1
作者 Jingjin XU Hong CHEN +3 位作者 Jing ZHANG Jiaji LI Ye LI Ling TANG 《Journal of Integrative Nursing》 2023年第2期151-154,共4页
Traditional Chinese medicine breast massage,also known as breast Tuina or manual expression of breast milk,is a technique of using certain manipulations to act on specific positions or acupoints of the breast to promo... Traditional Chinese medicine breast massage,also known as breast Tuina or manual expression of breast milk,is a technique of using certain manipulations to act on specific positions or acupoints of the breast to promote blood and lymphatic circulation of breast and facilitate the discharge of stagnant milk.This technique is widely used in China to treat breastfeeding problems such as breast engorgement,mastitis,and postpartum hypogalactia.In this article,we introduce the definition and standardization process of breast massage,elaborate the operating procedures of breast massage in detail,and summarize and discuss the current situation of its clinical application,so as to provide a reference for its wide application and in‑depth research. 展开更多
关键词 Breast massage breast milk expression operating procedures traditional Chinese medicine TUINA
下载PDF
The Efficacy and Safety of Dinoprostone Vaginal Insert for Labor Induction Following Optimization of Standard Operating Procedure: A Retrospective Study in China
2
作者 Ping Jin Bao-Min Yin 《Journal of Clinical and Nursing Research》 2023年第4期110-119,共10页
Background:The study aimed to assess the efficacy and safety of dinoprostone vaginal insert in labor induction following optimization of standard operating procedure(SOP)and to discover independent predictors of vagin... Background:The study aimed to assess the efficacy and safety of dinoprostone vaginal insert in labor induction following optimization of standard operating procedure(SOP)and to discover independent predictors of vaginal delivery.Methods:This study comprised 551 pregnant women who required cervical ripening with dinoprostone before induction of labor.Using univariate and multivariate analyses,independent predictors of vaginal delivery were identified.Results:443 of the 551 women(80.4%)gave birth vaginally.Vaginal delivery was predicted by maternal age(24-30 vs.<24,P<0.001;30-35 vs.<24,P=0.03),gestational age(P=0.005),birth weight(P<0.001),parity(P=0.001),pre-pregnancy BMI(P<0.001),premature rupture of membranes(P=0.001),meconium-stained amniotic fluid(P<0.001),fundal height(P<0.001)and the Bishop score(P<0.001).None of the women exhibited severe postpartum hemorrhage.Conclusions:The maternal age,gestational age,birth weight,parity,body mass index,premature membrane rupture,amniotic fluid contamination,fundal height,and the Bishop score were independent predictors of vaginal delivery.These may guide the clinical use of dinoprostone for induction of labor. 展开更多
关键词 Dinoprostone vaginal insert Induction of labor Standard operating procedure Vaginal delivery
下载PDF
Automatic Synthesis of Batch Process Operating Procedures
3
作者 王保国 王春艳 +1 位作者 许锡恩 Allen R.Wright 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 1998年第1期46-53,共8页
A three-step synthesis strategy for the automatic synthesis of operating procedures in batch processoperations is presented in this paper.The first step is pre-operation which consists of a set of checks that mustbe c... A three-step synthesis strategy for the automatic synthesis of operating procedures in batch processoperations is presented in this paper.The first step is pre-operation which consists of a set of checks that mustbe considered before starting the basic process operation.The second step is operation which is described by a setof basic control instructions.The third step is post-operation described by a set of instructions that must becarried out when the basic process operation is terminated.The three-step synthesis method has been imple-mented as part of a prototype recipe management system. 展开更多
关键词 BATCH PROCESS operating procedure control STEP
下载PDF
Investigation and analysis of clinical trial research nurse to perform standard operating procedures
4
作者 Yan Lin Yan-Yun Wu +2 位作者 M ei-Hua Wu Xiu-Yu Yang Ming Zhou 《Chinese Nursing Research》 CAS 2016年第2期77-79,共3页
Objective: The aim of this study was to investigate the situations and factors that cause nurses not to follow standard operating procedures (SOPs) during the clinical trial process. Methods: Five cases involving ... Objective: The aim of this study was to investigate the situations and factors that cause nurses not to follow standard operating procedures (SOPs) during the clinical trial process. Methods: Five cases involving patients enrolled in a clinical trial were divided into two groups, pre-SOP training and post-SOP training, to compare and observe the process problems and whether nurses fol- lowed SOPs in clinical trials. The causes of problems were analyzed and corrective measures were proposed. Results: Our results indicate significant improvement in compliance with SOPs after training. There were three occurrences of irregular behavior after training compared with 21 occurrences of irregular behavior before training. Conclusions: The quality of clinical trials can be improved if nurses strictly follow SOPs. 展开更多
关键词 Clinical trialStandard operating procedures (SOP)NurseInvestigationAnalysis
下载PDF
Operational procedures of auricular point sticking technology 被引量:1
5
作者 Hong CHEN Shanshan LIU +2 位作者 Kexin LIU Suna LI Ling TANG 《Journal of Integrative Nursing》 2022年第2期97-102,共6页
As an external treatment technique of traditional Chinese medicine(TCM),auricular point sticking,which is rooted in holographic biology theory and TCM viscera and meridian theory,is a safe and effective treatment meth... As an external treatment technique of traditional Chinese medicine(TCM),auricular point sticking,which is rooted in holographic biology theory and TCM viscera and meridian theory,is a safe and effective treatment method.This article introduces the technology overview and development process.The auricular point sticking technique for constipation is taken as an example to specify the basic requirements,assessment,operational points,acupoint selection and matters needing attention during the implementation of the auricular acupressure technique,providing a reference for the operating procedures of this technique in the clinical treatment of other diseases such as insomnia,diarrhea,colds,hypertension,headache,and dysmenorrhea. 展开更多
关键词 Auricular acupressure auricular point massage auricular point sticking operating procedures TECHNOLOGY traditional Chinese medicine nursing
下载PDF
Research on the Operation Mechanism of Claim in Civil Procedure Law and the Applications on Court Trial Way Reform
6
作者 Dan Liu 《International Journal of Technology Management》 2016年第4期10-12,共3页
In this paper, we conduct research on the operation mechanism of claim in civil procedure law and the applications on the court trial way reform. The ultimate goal of the rule of law lies in identifying and protecting... In this paper, we conduct research on the operation mechanism of claim in civil procedure law and the applications on the court trial way reform. The ultimate goal of the rule of law lies in identifying and protecting the rights of citizens. Way to protect the rights of citizens is diverse, but the judicial relief is the most basic and important form of insurance. Everyone can “into” the court and get the impartiality of the judicial relief, is a measure of a country judicial level height and the rule of law implementation degree of important yardstick. Judicial system and judicial procedure to build and build a better, if the subject of litigation rights are not being met and the safeguard, can’t get through the door and it is the legislators and legal scholars over the many efforts are meaningless, under this basic condition, we propose the new perspective on the corresponding issues that is necessary. 展开更多
关键词 operation Mechanism CIVIL procedure COURT TRIAL WAY REFORM Law Optimization
下载PDF
Approximation Solutions of Nonlinear Strongly Accretive Operator Equations by Ishikawa Iteration Procedure with Errors
7
作者 Luchuan Zeng 《Numerical Mathematics A Journal of Chinese Universities(English Series)》 SCIE 2006年第1期31-39,共9页
<正>Let 1<ρ≤2,E be a real ρ-uniformly smooth Banach space and T:E→E be a continuous and strongly accretive operator.The purpose of this paper is to investigate the problem of approximating solutions to the ... <正>Let 1<ρ≤2,E be a real ρ-uniformly smooth Banach space and T:E→E be a continuous and strongly accretive operator.The purpose of this paper is to investigate the problem of approximating solutions to the equation Tx=f by the Ishikawa iteration procedure with errors (?) where x_0 ∈ E,{u_n},{υ_n}are bounded sequences in E and{α_n},{b_n},{c_n},{a_n~'},{b_n~'},{c_n~'} are real sequences in[0,1].Under the assumption of the condition 0<α≤b_n+c_n,An≥0, it is shown that the iterative sequence{x_n}converges strongly to the unique solution of the equation Tx=f.Furthermore,under no assumption of the condition(?)(b_n~'+c_n~')=0,it is also shown that{x_n}converges strongly to the unique solution of Tx=f. 展开更多
关键词 强增生算子方程 非线性 BANACH空间 平滑
下载PDF
AP1000 Operation Procedures System and Development 被引量:1
8
作者 F. Wen 《Journal of Energy and Power Engineering》 2011年第8期711-717,共7页
下载PDF
基于S-Procedure的分段线性Delta算子系统的稳定性分析
9
作者 徐勇 石陆魁 +2 位作者 李杰 唐万生 张建雄 《计算机工程与科学》 CSCD 2008年第10期98-99,121,共3页
本文研究了一类由Delta算子描述的分段线性系统的二次稳定性问题。基于Delta域的Lyapunov稳定性理论,利用S-procedure构造了分段Lyapunov函数,而且将分段线性Delta算子系统的二次稳定性判定问题转化为一组线性矩阵不等式的求解问题。
关键词 DELTA算子 分段线性系统 S-procedure 二次稳定 线性矩阵不等式(LMI)
下载PDF
Modified Sugiura procedure for the management of 160 cirrhotic patients with portal hypertension 被引量:6
10
作者 You-Gang Ma, Xiao-Song Li, Jun Zhao, Han Chen and Meng-Chao Wu Department of Second Biliary Surgery, Eastern Hepa-tobiliary Hospital, Shanghai 200438, China 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2004年第3期399-401,共3页
BACKGROUND: Portal hypertension is a common diseasewith a high mortality and serious effect on the life quality ofpatients. Presently, shunt and disconnection are commonlyused for surgical treatment of portal hyperten... BACKGROUND: Portal hypertension is a common diseasewith a high mortality and serious effect on the life quality ofpatients. Presently, shunt and disconnection are commonlyused for surgical treatment of portal hypertension. The aimof this study was conducted to analyze the results of a modi-fied Sugiura procedure for the management of 160 cirrhoticpatients with portal hypertension.METHODS: The results of a modified Sugiura procedurefor the treatment of 160 cirrhotic patients with portal hyper-tension from January 1991 to July 2002 were retrospectivelyanalyzed.RESULTS: The operative mortality for the procedure waszero. Postoperative intra-abdominal bleeding was noted in2 patients, drowned lung in 1, pneumonia in 1, and splenicvenous thrombosis in 4. Of the 160 patients, 157 (98%)were followed up from 6 months to 11.5 years. Of the 157patients, only one died of hepatic coma 6 years after opera-tion, and 3 of rebleeding. The absolute and relative survivalrates were 97.5% (156/160) and 99% (159/160), respective-ly. The absolute and relative occurrence rates of hepatic co-ma were 2.5% (4/160) and 0.6% (1/157), respectively. Theabsolute and relative occurrence rates of rebleeding were3.8% (6/160) and 1.9% (3/157) , respectively. In 96 of 116Child B patients (82.8%), liver function improved frompreoperative class B to A 3 months after operation. Sixty-five patients were subjected to gastroscopy and 22 patients,esophageal barium photography 6 months after operation.Gastro-esophageal varices disappeared in 56 patients(64.4%, 56/87), obviously improved in 30 (34.5%, 30/87),and unchanged in 1 (1.2%, 1/87). The occurrence rate ofportal hypertensive gastropathy (PHG) was 13.9% (9/65).CONCLUSION: Our results showed that the modifiedSugiura procedure is effective in the treatment of portal hy-pertension, with a low rate of operative complication,bleeding recurrence, and hepatic coma. 展开更多
关键词 hypertension portal surgical procedure operative
下载PDF
Model for end-stage liver disease score versus Child score in predicting the outcome of surgical procedures in patients with cirrhosis 被引量:16
11
作者 Maarouf A Hoteit Amaar H Ghazale +4 位作者 Andrew J Bain Eli S Rosenberg Kirk A Easley Frank A Anania Robin E Rutherford 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第11期1774-1780,共7页
AIM:To determine factors affecting the outcome of patients with cirrhosis undergoing surgery and to compare the capacities of the Child-Turcotte-Pugh(CTP) and model for end-stage liver disease(MELD)score to predict th... AIM:To determine factors affecting the outcome of patients with cirrhosis undergoing surgery and to compare the capacities of the Child-Turcotte-Pugh(CTP) and model for end-stage liver disease(MELD)score to predict that outcome. METHODS:We reviewed the charts of 195 patients with cirrhosis who underwent surgery at two teaching hospitals over a five-year period.The combined endpoint of death or hepatic decompensation was considered to be the primary endpoint. RESULTS:Patients who reached the endpoint had a higher MELD score,a higher CTP score and were more likely to have undergone an urgent procedure.Among patients undergoing elective surgical procedures,no statistically significant difference was noted in the mean MELD(12.8±3.9 vs 12.6±4.7,P=0.9)or in the mean CTP(7.6±1.2 vs 7.7±1.7,P=0.8)between patients who reached the endpoint and those who did not.Both mean scores were higher in the patients reaching the endpoint in the case of urgent procedures(MELD:22.4± 8.7 vs 15.2±6.4,P=0.0007;CTP:9.9±1.8 vs 8.5±1.8, P=0.008).The performances of the MELD and CTP scores in predicting the outcome of urgent surgery were only fair,without a significant difference between them (AUC=0.755±0.066 for MELD vs AUC=0.696±0.070 for CTP,P=0.3). CONCLUSION:The CTP and MELD scores performedequally,but only fairly in predicting the outcome of urgent surgical procedures.Larger studies are needed to better define the factors capable of predicting the outcome of elective surgical procedures in patients with cirrhosis. 展开更多
关键词 肝硬化 预后 手术治疗 外科规程 并发症
下载PDF
Monte Carlo Study of 3D Stray Radiation during Interventional Procedures
12
作者 Khalid S. Alzimami 《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》 2018年第4期453-463,共11页
In interventional medical procedures, other than the highly important issue of optimizing image quality and patient exposure using the primary beam, there remains a continuing need for the study of staff exposure from... In interventional medical procedures, other than the highly important issue of optimizing image quality and patient exposure using the primary beam, there remains a continuing need for the study of staff exposure from the scattered radiation. Herein, investigation is made of the 3D stray-radiation distribution, the simulation being made of a realistic interventional scenario through use of the Monte Carlo code Geant4 (version 10.3). The simulation is conducted based on the high definition reference Korean-man (HDRK-man) computational phantom and a GE Infinia 3/8” C-arm machine, focusing on the effect of variation of kVp and field of view (FoV) on the scattered particles’ spatial distribution. With direct measurement of the absorbed dose remaining challenging, not least in respect of the organs at risk, we computed the scatter fractions, defined as the ratio of the air kerma free-in-air to the entrance surface air kerma (ESAK), which are both easily quantifiable. Scatter fraction distributions were simulated for X-ray tube outputs (and half-value layers, HVL) of 60 kVp (2.3 mm Al), 80 kVp (3.2 mm Al) and 120 kVp (4.3 mm Al) and FoV of 15, 20, 25 and 30 cm. The distributions are obtained for different height levels, corresponding to the lens of the eye, and the lung and prostate, all radiosensitive organs. Investigations are made for eight likely locations around the patient. At fixed FoV results reveal an inverse relationship between ESAK and kVp, also that change in kVp from 60 to 80 has a greater effect than from 80 to 120. For change in FoV at fixed kVp, the scatter fraction remains constant. The particular staff locations are found to be optimal in seeking mitigation of dose. Moreover, the combined usage of numerical human model and Monte Carlo simulation can be considered as an added value to the radiation safety research field, especially to the interventional radiology staff and to the patient. 展开更多
关键词 Stray RADIATION INTERVENTIONAL procedureS operATOR EXPOSURE GEANT4
下载PDF
Information Fusion for Process Acquisition in the Operating Room
13
作者 Thomas Neumuth Christian Meiвner 《Open Journal of Applied Sciences》 2012年第4期195-198,共4页
The recognition of surgical processes in the operating room is an emerging research field in medical engineering. We present the design and implementation of a instrument localization system that is based on informati... The recognition of surgical processes in the operating room is an emerging research field in medical engineering. We present the design and implementation of a instrument localization system that is based on information fusion strategies to enhance its recognition power. The system was implemented using RFID technology. It monitored the presence of surgical tools in the interventional site and the instrument tray and combined the measured information by applying redundant, complementary, and cooperative information fusion strategy to achieve a more comprehensive model of the current situation. An evaluation study was performed that showed a correct classification rate of 97% for the system. 展开更多
关键词 surgical procedure WORKFLOW proces modeling operating room computer-assisted surgery information fusion
下载PDF
Radiation therapy prior to a pancreaticoduodenectomy for adenocarcinoma is associated with longer operative times and higher blood loss
14
作者 Krist Aploks Minha Kim +6 位作者 Stephanie Stroever Alexander Ostapenko Young Bo Sim Ashwinkumar Sooriyakumar Arash Rahimi-Ardabily Ramanathan Seshadri Xiang Da Dong 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第8期1663-1672,共10页
BACKGROUND Pancreatic adenocarcinoma is currently the fourth leading cause of cancer-related deaths in the United States.In patients with“borderline resectable”disease,current National Comprehensive Cancer Center gu... BACKGROUND Pancreatic adenocarcinoma is currently the fourth leading cause of cancer-related deaths in the United States.In patients with“borderline resectable”disease,current National Comprehensive Cancer Center guidelines recommend the use of neoadjuvant chemoradiation prior to a pancreaticoduodenectomy.Although neoadjuvant radiotherapy may improve negative margin resection rate,it is theorized that its administration increases operative times and complexity.AIM To investigate the association between neoadjuvant radiotherapy and 30-d morbidity and mortality outcomes among patients receiving a pancreaticoduodenectomy for pancreatic adenocarcinoma.METHODS Patients listed in the 2015-2019 National Surgery Quality Improvement Program data set,who received a pancreaticoduodenectomy for pancreatic adenocarcinoma,were divided into two groups based off neoadjuvant radiotherapy status.Multivariable regression was used to determine if there is a significant correlation between neoadjuvant radiotherapy,perioperative blood transfusion status,total operative time,and other perioperative outcomes.RESULTS Of the 11458 patients included in the study,1470(12.8%)underwent neoadjuvant radiotherapy.Patients who received neoadjuvant radiotherapy were significantly more likely to require a perioperative blood transfusion[adjusted odds ratio(aOR)=1.58,95%confidence interval(CI):1.37-1.82;P<0.001]and have longer surgeries(insulin receptor-related receptor=1.14,95%CI:1.11-1.16;P<0.001),while simultaneously having lower rates of organ space infections(aOR=0.80,95%CI:0.66-0.97;P=0.02)and pancreatic fistula formation(aOR=0.50,95%CI:0.40-0.63;P<0.001)compared to those who underwent surgery alone.CONCLUSION Neoadjuvant radiotherapy,while not associated with increased mortality,will impact the complexity of surgical resection in patients with pancreatic adenocarcinoma. 展开更多
关键词 PANCREATICODUODENECTOMY Pancreatic adenocarcinoma Neoadjuvant chemoradiation National Surgery Quality Improvement Program Whipple procedure operative time
下载PDF
Technical operation specification for cupping therapy
15
作者 Yongchun WEI Yali WANG +2 位作者 Haiyan E Kaiye ZHANG Ling TANG 《Journal of Integrative Nursing》 2023年第2期155-160,共6页
Cupping,as one of the characteristic therapies of traditional Chinese medicine,has been applied for more than 2000 years and has a unique curative effect in clinic.With the evolution of the times,the types and operati... Cupping,as one of the characteristic therapies of traditional Chinese medicine,has been applied for more than 2000 years and has a unique curative effect in clinic.With the evolution of the times,the types and operation techniques of cupping method are also iterating.In the process of its inheritance and development,cupping technology is also known by more and more people.Starting from the development and efficacy of cupping method,this paper introduces the clinical operation steps and precautions of cupping method in detail,and lists the representative diseases such as lumbar muscle strain,herpes zoster,and ankylosing spondylitis,to provide reference for clinical application. 展开更多
关键词 CUPPING nursing technology operating procedures traditional Chinese medicine
下载PDF
Technical operation specification for pricking-cupping therapy
16
作者 Jiaji LI Jingjin XU +3 位作者 Jing ZHANG Ling TANG Hong CHEN Ye LI 《Journal of Integrative Nursing》 2023年第3期223-227,共5页
Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and... Pricking-cupping therapy is a Traditional Chinese Medicine(TCM)nursing technology that can adjust the viscera of the human body,make the meridians smooth,and Yin and Yang balanced mainly by means of relieving heat and detoxification,harmonizing Qi and blood,promoting blood circulation and removing blood stasis,dredging meridians and activating collaterals,reducing swelling and pain,purging heat and calming shock,clearing heat,and opening orifices.Pricking-cupping therapy has a long history and wide application.After thousands of years of development,it has made great progress.They are widely used to treat lumbar disc herniation,herpes zoster,acute arthritis,migraine,and other diseases in China.Through the clinical practice and theoretical exploration of physicians of past dynasties,the therapeutic mechanism and application scope of pricking-cupping therapy have been greatly enriched.Modern TCM practitioners have conducted in-depth researches on the operation norms of the therapy on the basis of the ancients,hoping to grasp the essence of the disease more accurately and make the rational use of the operation technology of the therapy. 展开更多
关键词 Bloodletting puncture CUPPING external treatment of traditional Chinese medicine operating procedures pricking-cupping therapy Traditional Chinese Medicine nursing technology
下载PDF
Enhancing Operational Efficiency: Exploring the Integration of SOPs Using Virtual Reality and Smart Glasses Technology in Food Manufacturing
17
作者 Somil Nishar 《Intelligent Control and Automation》 2023年第3期37-44,共8页
This paper explores the integration of Standard Operating Procedures (SOPs) using virtual reality and smart glasses technology in food manufacturing. The study employs a thorough methodology, combining observational i... This paper explores the integration of Standard Operating Procedures (SOPs) using virtual reality and smart glasses technology in food manufacturing. The study employs a thorough methodology, combining observational insights to develop a comprehensive SOP. Implementation at different firms resulted in significant improvements, reducing product waste and enhancing overall efficiency. The use of virtual reality further augments SOP adoption. The findings underscore SOPs’ transformative influence, offering a tangible solution to challenges in the food production sector. Recommendations include regular SOP reviews and ongoing training for sustained success. Different firms exemplify SOPs as indispensable tools for operational excellence. 展开更多
关键词 Smart Manufacturing Standard operating procedures 5S Six Sigma Lean Manufacturing Augmented Reality Smart Glasses Food Manufacturing TR Toppers Industry 4.0
下载PDF
低温等离子治疗儿童鼻咽部第二鳃裂囊肿分析
18
作者 温鑫 黄爱萍 +5 位作者 张爱英 许敏 宋英鸾 崔莉 耿江桥 史静 《中国耳鼻咽喉头颈外科》 CSCD 2024年第1期54-56,共3页
目的探讨儿童鼻咽部第二鳃裂囊肿的临床特征和治疗方式,提高诊治能力。方法回顾性分析河北省儿童医院收治的4例儿童鼻咽部第二鳃裂囊肿的临床资料,包括年龄、性别、症状、影像学资料和治疗过程。总结分析病变部位特点,B超、CT或MRI特征... 目的探讨儿童鼻咽部第二鳃裂囊肿的临床特征和治疗方式,提高诊治能力。方法回顾性分析河北省儿童医院收治的4例儿童鼻咽部第二鳃裂囊肿的临床资料,包括年龄、性别、症状、影像学资料和治疗过程。总结分析病变部位特点,B超、CT或MRI特征,术后病理结果及治疗方式。结果4例鼻咽部第二鳃裂囊肿患儿均表现为鼻咽侧壁咽鼓管咽口与腭咽弓后上方连线上的囊性肿物,囊壁较厚,影像学检查结果均为囊性病变。4例患儿选择内镜下低温等离子病变切除术,其中2例为内侧囊壁大部分切除术,将囊腔充分敞开,2例为囊肿全部切除术。术后病理提示衬覆纤毛柱状上皮或复层上皮,周围淋巴组织增生。术后随访1.5~3年无复发。结论儿童鼻咽部第二鳃裂囊肿临床罕见,诊断主要依靠病变部位及术后病理结果,内镜下低温等离子切除病变组织是微创、安全、有效的治疗方式。 展开更多
关键词 儿童(Child) 外科手术(Surgical procedures operative) 鼻咽部第二鳃裂囊肿(nasopharyngeal cyst of second branchial cleft) 低温等离子(low temperature plasma)
下载PDF
多灶性肝母细胞瘤手术切除的单中心研究
19
作者 杨维 刘珊 +8 位作者 任清华 王焕民 秦红 成海燕 常晓峰 朱志云 冯俊 韩建宇 杨深 《临床小儿外科杂志》 CAS CSCD 北大核心 2024年第6期543-549,共7页
目的探讨多灶性肝母细胞瘤(hepatoblastoma,HB)手术切除治疗的可行性及有效性。方法本研究为回顾性研究,以2014年4月至2022年12月首都医科大学附属北京儿童医院肿瘤外科收治的21例多灶性HB患儿为研究对象,收集患儿临床特征、手术方式及... 目的探讨多灶性肝母细胞瘤(hepatoblastoma,HB)手术切除治疗的可行性及有效性。方法本研究为回顾性研究,以2014年4月至2022年12月首都医科大学附属北京儿童医院肿瘤外科收治的21例多灶性HB患儿为研究对象,收集患儿临床特征、手术方式及远期预后等资料,并与同期收治的58例中高危单灶性HB患儿进行疗效对比。结果21例多灶性HB患儿中,11例为2个瘤灶,4例为3个瘤灶,1例为5个瘤灶,5例肝内瘤灶超过5个且无法明确计数。21例均接受肿瘤切除手术,其中9例行解剖性肝切除术,11例行不规则肝切除或瘤灶剜除术,1例行联合肝脏离断及门静脉结扎的分次肝切除术(associating liver partition and portal vein ligation for staged hepatectomy,ALPPS)。20例为R0切除,1例为R1切除,术后无一例发生严重并发症。本组多灶性HB患儿接受手术联合化疗的多学科综合治疗后,中位随访时间57个月,18例患儿无瘤生存,3例死亡。本组多灶性HB患儿3年无事件生存率(event-free survival,EFS)为57.58%,3年总生存率(overall survival,OS)为82.00%,局部进展累积发生率(cumulative incidence of local progression,CILP)为38.00%。同期收治的单灶性中高危HB患儿上述指标分别为91.84%、74.96%、20.04%。两组数据对比,差异无统计学意义(P>0.05)。结论多灶性HB经规范外科手术切除辅助术前、术后化疗,可以获得较为满意的预后。 展开更多
关键词 肝母细胞瘤 外科手术 治疗结果 临床研究 儿童
下载PDF
细胞减灭术联合腹腔热灌注化疗在局部反复复发肾母细胞瘤治疗中的应用
20
作者 常晓峰 王焕民 +5 位作者 王佳荣 孟德光 秦红 杨维 成海燕 朱志云 《临床小儿外科杂志》 CAS CSCD 北大核心 2024年第5期464-468,共5页
目的观察细胞减灭术(cytoreductive surgery,CRS)联合腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)对反复复发肾母细胞瘤的腹腔局部控制情况。方法本研究为回顾性研究,以2019年1月至2022年1月首都医科大学附属北... 目的观察细胞减灭术(cytoreductive surgery,CRS)联合腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)对反复复发肾母细胞瘤的腹腔局部控制情况。方法本研究为回顾性研究,以2019年1月至2022年1月首都医科大学附属北京儿童医院肿瘤外科及北京儿童医院保定医院肿瘤外科收治的6例反复复发的肾母细胞瘤患儿为研究对象,收集患儿基本信息(性别、年龄、发病部位等)、既往治疗经过、治疗方案以及本中心(北京与保定两个病区)手术、热灌注、术后治疗及随访情况。结果6例反复复发的肾母细胞瘤患儿均为单侧病变,5例行根治性瘤肾切除术,1例行保留肾脏肿瘤剥除术。4例直接接受手术,参考COG分期,其中2例为Ⅲ期,行化疗+放疗;2例为Ⅱ期,予以化疗;另2例术前予以化疗,参考SIOP分期,术后诊断为Ⅱ期,术后仅行化疗。初次复发时间最短为术后1.5个月,最长为术后10个月,其中3例为原位复发,2例为腹盆腔单发种植病灶,1例为肠系膜多发病变。在治疗过程中,6例复发部位均位于腹盆腔,未见远处转移,且均接受了手术切除;5例进行了局部放疗;6例术后均采用了强于初次化疗的个体化治疗方案。6例在本中心治疗过程中均接受了细胞减灭术+术中腹腔热灌注化疗,术中、术后均未见危及生命的严重并发症;随访时间为14(2,32)个月,其中4例长期生存,2例死于肿瘤进展。结论局部反复复发的肾母细胞瘤预后差,在化疗的辅助下,CRS+HIPEC可以最大程度杀灭可能残存的肿瘤细胞,更有利于肿瘤局部控制。 展开更多
关键词 细胞减灭术 腹腔热灌注化疗 肾母细胞瘤 外科手术 儿童
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部