Objective:To evaluate the clinical effect of Tongren Dahuoluo Pill(同仁大活络丸)on knee osteoarthritis by musculoskeletal ultrasonography.Methods:From March 2019 to December 2019,45 patients with knee osteoarthritis w...Objective:To evaluate the clinical effect of Tongren Dahuoluo Pill(同仁大活络丸)on knee osteoarthritis by musculoskeletal ultrasonography.Methods:From March 2019 to December 2019,45 patients with knee osteoarthritis were collected from the outpatient department of the First Medical Center of PLA General Hospital.Tongren Dahuoluo Pill(同仁大活络丸)was given oral treatment for 12 weeks.VAS score,Lequesne score and WOMAC score were recorded before and after treatment,and the changes of knee joint effusion and synovial hyperplasia were observed by musculoskeletal ultrasonography.Results:Among the 45 patients,18 were male and 27 were female,with the average age of(62.07±9.08)years old,and average disease course of(6.83±7.01)years.The VAS score,Lequesne score and WOMAC score were significantly reduced compared with before treatment,and the difference was statistically significant(P<0.01).We observed that joint effusion range and joint synovial hyperplasia thickness of knee osteoarthritis significantly reduced with Tongren Dahuoluo Pill(同仁大活络丸)treatment by musculoskeletal ultrasonography,and the difference were statistically significant(P<0.01).Conclusion:Tongren Dahuoluo Pill(同仁大活络丸)can not only relieve the clinical symptoms of knee osteoarthritis,but also effectively inhibit synovitis hyperplasia of knee joint.展开更多
目的观察电针透刺和Mulligan动态关节松动术治疗轻中度膝骨关节炎(knee osteoarthfitis,KOA)的临床疗效,探寻安全有效的中西医结合治疗方案。方法将90例来自长沙市中心医院的轻中度KOA患者随机分为电针透刺组、关节松动组和联合组,每组3...目的观察电针透刺和Mulligan动态关节松动术治疗轻中度膝骨关节炎(knee osteoarthfitis,KOA)的临床疗效,探寻安全有效的中西医结合治疗方案。方法将90例来自长沙市中心医院的轻中度KOA患者随机分为电针透刺组、关节松动组和联合组,每组30例。电针透刺组即在透刺基础上连接电针仪,关节松动组采用Mulligan动态关节松动术治疗,联合组即电针透刺结合Mulligan动态关节松动术。各组均每天治疗1次,每周治疗5次,共治疗6周。在治疗前及治疗6周后,通过疼痛视觉模拟评分(visual analogue scale,VAS)、西安大略和麦克马斯特大学骨关节炎指数(Western Ontario and McMaster Universities arthritis index,WOMAC)、Lysholm膝关节功能评估量表、膝关节最大主动关节活动度(active range of motion,AROM)、髌上囊积液及关节间隙角等指标综合评定疗效。结果治疗后,3组患者的VAS、WOMAC评分较治疗前均有下降,Lysholm评分、AROM较治疗前均有提高,关节间隙角较治疗前减小,髌上囊积液量较治疗前减少(P<0.05);联合组的上述指标较电针透刺组、关节松动组改善更明显(P<0.05);电针透刺组在减少髌上囊积液方面优于关节松动组(P<0.05);关节松动组在增加膝关节AROM、缩小关节间隙角方面优于电针透刺组(P<0.05)。结论电针透刺及Mulligan动态关节松动术均能不同程度缓解轻中度KOA患者疼痛症状,降低髌上囊积液量,缩小关节间隙角,改善膝关节整体功能,且二者联合疗效更佳。展开更多
文摘Objective:To evaluate the clinical effect of Tongren Dahuoluo Pill(同仁大活络丸)on knee osteoarthritis by musculoskeletal ultrasonography.Methods:From March 2019 to December 2019,45 patients with knee osteoarthritis were collected from the outpatient department of the First Medical Center of PLA General Hospital.Tongren Dahuoluo Pill(同仁大活络丸)was given oral treatment for 12 weeks.VAS score,Lequesne score and WOMAC score were recorded before and after treatment,and the changes of knee joint effusion and synovial hyperplasia were observed by musculoskeletal ultrasonography.Results:Among the 45 patients,18 were male and 27 were female,with the average age of(62.07±9.08)years old,and average disease course of(6.83±7.01)years.The VAS score,Lequesne score and WOMAC score were significantly reduced compared with before treatment,and the difference was statistically significant(P<0.01).We observed that joint effusion range and joint synovial hyperplasia thickness of knee osteoarthritis significantly reduced with Tongren Dahuoluo Pill(同仁大活络丸)treatment by musculoskeletal ultrasonography,and the difference were statistically significant(P<0.01).Conclusion:Tongren Dahuoluo Pill(同仁大活络丸)can not only relieve the clinical symptoms of knee osteoarthritis,but also effectively inhibit synovitis hyperplasia of knee joint.
文摘目的观察电针透刺和Mulligan动态关节松动术治疗轻中度膝骨关节炎(knee osteoarthfitis,KOA)的临床疗效,探寻安全有效的中西医结合治疗方案。方法将90例来自长沙市中心医院的轻中度KOA患者随机分为电针透刺组、关节松动组和联合组,每组30例。电针透刺组即在透刺基础上连接电针仪,关节松动组采用Mulligan动态关节松动术治疗,联合组即电针透刺结合Mulligan动态关节松动术。各组均每天治疗1次,每周治疗5次,共治疗6周。在治疗前及治疗6周后,通过疼痛视觉模拟评分(visual analogue scale,VAS)、西安大略和麦克马斯特大学骨关节炎指数(Western Ontario and McMaster Universities arthritis index,WOMAC)、Lysholm膝关节功能评估量表、膝关节最大主动关节活动度(active range of motion,AROM)、髌上囊积液及关节间隙角等指标综合评定疗效。结果治疗后,3组患者的VAS、WOMAC评分较治疗前均有下降,Lysholm评分、AROM较治疗前均有提高,关节间隙角较治疗前减小,髌上囊积液量较治疗前减少(P<0.05);联合组的上述指标较电针透刺组、关节松动组改善更明显(P<0.05);电针透刺组在减少髌上囊积液方面优于关节松动组(P<0.05);关节松动组在增加膝关节AROM、缩小关节间隙角方面优于电针透刺组(P<0.05)。结论电针透刺及Mulligan动态关节松动术均能不同程度缓解轻中度KOA患者疼痛症状,降低髌上囊积液量,缩小关节间隙角,改善膝关节整体功能,且二者联合疗效更佳。