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Modulation of starch digestibility using non-thermal processing techniques:A review
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作者 Liyuan Rong Weiqi Fei +4 位作者 Zhijun Wang Xianxiang Chen Huiliang Wen Jianhua Xie Mingyue Shen 《Grain & Oil Science and Technology》 CAS 2024年第3期209-218,共10页
Obesity and type 2 diabetes are widespread throughout the world, especially in developed countries. Starch is an important part of human staple food, the modulating of starch digestibility is conducive to reducing pos... Obesity and type 2 diabetes are widespread throughout the world, especially in developed countries. Starch is an important part of human staple food, the modulating of starch digestibility is conducive to reducing postprandial blood glucose levels and alleviating the chronic disease caused by high caloric intake. The digestion properties of starch are correlated with its structural features, including crystallization, amylose/amylopectin ratio, non-starch components, etc. Among the modified methods applied to regulate starch digestibility, non-thermal processing techniques(NTPT) receive extensive attention due to the characteristics of safety, environmental friendliness and high efficiency. The influence and mechanism of NTPT on the digestion properties of starch are discussed in this review, including ultrasounds, high pressure, γ-irradiation, etc. NTPT induces the alternation of morphological and structural characteristics of native starch, changing their sensitivity to enzymes. The effects of NTPT on the digestibility of starch are highly related to the processing parameters and structure characteristics of native starch. The review shows that NTPT is an effective way to modulate the digestion properties of starch and prevent people from suffering from chronic diseases such as obesity and type 2 diabetes. 展开更多
关键词 DIGESTIBILITY non-thermal processing Chronic disease STARCH
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Non-thermal plasma enhanced catalytic conversion of methane into value added chemicals and fuels
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作者 Shanza Baig Baharak Sajjadi 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第10期265-301,I0006,共38页
Plasma catalysis has recently gained increased attention for its application in gas conversion,notably in processes like the dry reforming of methane aimed at transforming them into valuable chemicals and fuels.As thi... Plasma catalysis has recently gained increased attention for its application in gas conversion,notably in processes like the dry reforming of methane aimed at transforming them into valuable chemicals and fuels.As this field is still in its early developmental stages,there is a crucial necessity to explore the synergistic mechanism between plasma and catalysts.The optimization of catalysts is imperative to improve their selectivity and conversion rates for desired products in a plasma environment.Additionally,delving into microscale investigations of plasma characteristics,such as electron temperature and the density of energetic species,is essential to enhance the stability and activity of catalysts.This review examines recent advancements in various methane conversion techniques,encompassing Dry Reforming of Methane,Steam Methane Reforming,Pa rtial Oxidation of Metha ne,and Methane Decomposition utilizing non-thermal dielectric barrier discharge(DBD)plasma.The aim is to gain a deeper understanding of plasma-catalyst interactions and to refine catalyst selection strategies for maximizing the production of desired products such as syngas,oxygenates,or higher hydrocarbons.The review delves into the catalytic mechanisms that delineate the synergistic effects between DBD plasma and catalyst in each technology,shedding light on the role of diverse catalytic properties in activating methane molecules-a pivotal step in hybrid plasma-catalytic reactions.Various approaches employed by researchers in exploring suitable catalysts and optimal reaction conditions to bolster CH_(4) conversion rates and selectivity using DBD plasma are discussed.Additionally,the review identifies gaps in the realm of plasma catalysis,underscoring the necessity for further research to fully understand the underlying principles of plasma and catalyst which are not trivial to uncover. 展开更多
关键词 non-thermal plasma DBD CATALYST METHANE
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Sustainable ammonia synthesis:An in-depth review of non-thermal plasma technologies
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作者 Vahid Shahed Gharahshiran Ying Zheng 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第9期1-38,共38页
Ammonia serves both as a widely used fertilizer and environmentally friendly energy source due to its high energy density,rich hydrogen content,and emissions-free combustion.Additionally,it offers convenient transport... Ammonia serves both as a widely used fertilizer and environmentally friendly energy source due to its high energy density,rich hydrogen content,and emissions-free combustion.Additionally,it offers convenient transportation and storage as a hydrogen carrier.The dominant method used for large-scale ammonia production is the Haber-Bosch process,which requires high temperatures and pressures and is energy-intensive.However,non-thermal plasma offers an eco-friendly alternative for ammonia synthesis,gaining significant attention.It enables ammonia production at lower temperatures and pressures using plasma technology.This review provides insights into the catalyst and reactor developments,which are pivotal for promoting ammonia efficiency and addressing existing challenges.At first,the reaction kinetics and mechanisms are introduced to gain a comprehensive understanding of the reaction pathways involved in plasma-assisted ammonia synthesis.Thereafter,the enhancement of ammonia synthesis efficiency is discussed by developing and optimizing plasma reactors and effective catalysts.The effect of other feeding sources,such as water and methane,instead of hydrogen is also presented.Finally,the challenges and possible solutions are outlined to facilitate energy-saving and enhance ammonia efficiency in the future. 展开更多
关键词 Nitrogen fixation Ammonia synthesis NH_(3) non-thermal plasma NI Ru catalyst
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Dendritic spine degeneration:a primary mechanism in the aging process
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作者 Gonzalo Flores Leonardo Aguilar-Hernández +3 位作者 Fernado García-Dolores Humberto Nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán 《Neural Regeneration Research》 SCIE CAS 2025年第6期1696-1698,共3页
Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a w... Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(GM)(Mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(Mayer et al., 2022;AguilarHernández et al., 2023). 展开更多
关键词 AGING process STRESS
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Prediction and optimization of flue pressure in sintering process based on SHAP
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作者 Mingyu Wang Jue Tang +2 位作者 Mansheng Chu Quan Shi Zhen Zhang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS 2025年第2期346-359,共14页
Sinter is the core raw material for blast furnaces.Flue pressure,which is an important state parameter,affects sinter quality.In this paper,flue pressure prediction and optimization were studied based on the shapley a... Sinter is the core raw material for blast furnaces.Flue pressure,which is an important state parameter,affects sinter quality.In this paper,flue pressure prediction and optimization were studied based on the shapley additive explanation(SHAP)to predict the flue pressure and take targeted adjustment measures.First,the sintering process data were collected and processed.A flue pressure prediction model was then constructed after comparing different feature selection methods and model algorithms using SHAP+extremely random-ized trees(ET).The prediction accuracy of the model within the error range of±0.25 kPa was 92.63%.SHAP analysis was employed to improve the interpretability of the prediction model.The effects of various sintering operation parameters on flue pressure,the relation-ship between the numerical range of key operation parameters and flue pressure,the effect of operation parameter combinations on flue pressure,and the prediction process of the flue pressure prediction model on a single sample were analyzed.A flue pressure optimization module was also constructed and analyzed when the prediction satisfied the judgment conditions.The operating parameter combination was then pushed.The flue pressure was increased by 5.87%during the verification process,achieving a good optimization effect. 展开更多
关键词 sintering process flue pressure shapley additive explanation PREDICTION OPTIMIZATION
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An Unprecedented Efficiency with Approaching 21%Enabled by Additive‑Assisted Layer‑by‑Layer Processing in Organic Solar Cells
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作者 Shuai Xu Youdi Zhang +6 位作者 Yanna Sun Pei Cheng Zhaoyang Yao Ning Li Long Ye Lijian Zuo Ke Gao 《Nano-Micro Letters》 SCIE EI CAS 2025年第2期372-375,共4页
Recently published in Joule,Feng Liu and colleagues from Shanghai Jiaotong University reported a record-breaking 20.8%power conversion efficiency in organic solar cells(OSCs)with an interpenetrating fibril network act... Recently published in Joule,Feng Liu and colleagues from Shanghai Jiaotong University reported a record-breaking 20.8%power conversion efficiency in organic solar cells(OSCs)with an interpenetrating fibril network active layer morphology,featuring a bulk p-in structure and proper vertical segregation achieved through additive-assisted layer-by-layer deposition.This optimized hierarchical gradient fibrillar morphology and optical management synergistically facilitates exciton diffusion,reduces recombination losses,and enhances light capture capability.This approach not only offers a solution to achieving high-efficiency devices but also demonstrates the potential for commercial applications of OSCs. 展开更多
关键词 Organic solar cells Additive-assisted layer-by-layer processing Three-dimensional fibril morphology Bulk p-i-n structure Optical management
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Processing,microstructure,and mechanical properties of wire arc additively-manufactured AZ91 magnesium alloy using cold arc process
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作者 Bai-hao CAI Ji-kang FAN +3 位作者 Jie LI Dong-qing YANG Yong PENG Ke-hong WANG 《中国有色金属学报》 北大核心 2025年第1期91-104,共14页
Thin walls of an AZ91 magnesium alloy with fine equiaxed grains were fabricated via cold arc-based wire arc additive manufacturing(CA-WAAM),and the droplet transfer behaviours,microstructures,and mechanical properties... Thin walls of an AZ91 magnesium alloy with fine equiaxed grains were fabricated via cold arc-based wire arc additive manufacturing(CA-WAAM),and the droplet transfer behaviours,microstructures,and mechanical properties were investigated.The results showed that the cold arc process reduced splashing at the moment of liquid bridge breakage and effectively shortened the droplet transfer period.The microstructures of the deposited samples exhibited layered characteristics with alternating distributions of coarse and fine grains.During layer-by-layer deposition,the β-phase precipitated and grew preferentially along grain boundaries,while the fineη-Al_(8)Mn_(5)phase was dispersed in the α-Mg matrix.The mechanical properties of the CA-WAAM deposited sample showed isotropic characteristics.The ultimate tensile strength and elongation in the building direction(BD)were 282.7 MPa and 14.2%,respectively.The microhardness values of the deposited parts were relatively uniform,with an average value of HV 69.6. 展开更多
关键词 AZ91 magnesium alloy droplet transfer MICROSTRUCTURE mechanical properties cold arc process
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Influence of material characteristics on the failure mode and process of landslide dam
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作者 HU Liang ZHONG Qiming +3 位作者 CHEN Liang YANG Meng ZHANG Lucheng WU Hao 《Journal of Mountain Science》 2025年第1期89-109,共21页
Landslide dams,as frequent natural hazards,pose significant risks to human lives,property,and ecological environments.The grading characteristics and density of dam materials play a crucial role in determining the sta... Landslide dams,as frequent natural hazards,pose significant risks to human lives,property,and ecological environments.The grading characteristics and density of dam materials play a crucial role in determining the stability of landslide dams and the potential for dam breaches.To explore the failure mechanisms and evolutionary processes of landslide dams with varying soil properties,this study conducted a series of flume experiments,considering different grain compositions and material densities.The results demonstrated that grading characteristics significantly influence landslide dam stability,affecting failure patterns,breach processes,and final breach morphologies.Fine-graded materials exhibited a sequence of surface erosion,head-cut erosion,and subsequent surface erosion during the breach process,while well-graded materials typically experienced head-cut erosion followed by surface erosion.In coarse-graded dams,the high permeability of coarse particles allowed the dam to remain stable,as inflows matched outflows.The dam breach model experiments also showed that increasing material density effectively delayed the breach and reduced peak breach flow discharge.Furthermore,higher fine particle content led to a reduction in the residual dam height and the base slope of the final breach profile,although the relationship between peak breach discharge and the content of fine and coarse particles was nonlinear.To better understand breach morphology evolution under different soil characteristics and hydraulic conditions,three key points were identified—erosion point,control point,and scouring point.This study,by examining the evolution of failure patterns,breach processes,and breach flow discharges under various grading and density conditions,offers valuable insights into the mechanisms behind landslide dam failures. 展开更多
关键词 Landslide dams OVERTOPPING Grain size distribution Breaching process Outflow discharge
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New digital drilling process monitoring: Instrumentation, validation and calibration
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作者 Yanpeng Sun Zuyu Chen +3 位作者 Fangcai Xu Yufei Zhao Ruilang Cao Dong Li 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第1期31-54,共24页
This study aims to enhance the digital drilling process monitoring(DPM)or monitoring while drilling(MWD)technique,which is a widely recognized method in geological exploration for evaluating rock mass quality.First,ro... This study aims to enhance the digital drilling process monitoring(DPM)or monitoring while drilling(MWD)technique,which is a widely recognized method in geological exploration for evaluating rock mass quality.First,robust displacement and torque measurement facilities for rotary-core drilling are discussed.The conventional cable encoder for displacement measurement is replaced with a magnetostrictive displacement sensor,which is more reliable in harsh field drilling environments.This enables the measurement of the bit position with an accuracy of<1 mm.Most importantly,this new instrument is proven to be successful in improving the detection of structural discontinuities with thicknesses>1 mm.In addition,by measuring the electric current of the driving motor,the torque applied to the bit is conveniently and accurately converted.These innovations ensure high-quality data collection for DPM practices.Second,two indices derived from DPM are proposed to quantitatively describe rock mass quality.The specific energy index(SEI)and specific penetration index(SPI)are based on the principles of energy conservation and Mohr-Coulomb failure criterion,respectively.Extensive field tests conducted in a dam grouting area confirm a linear relationship between the thrust force and penetration per rotation,and between the torque and penetration per rotation.The correlation ratios of the related regressions are typically>0.9.These two indices allow for the quantitative interpretation of DPM data into rock mechanics characteristics,such as uniaxial compressive strength,rock quality designation(RQD),and rock mass permeability,eliminating the need for subjective judgment normally involved in the currently used rock mass quality rating approaches. 展开更多
关键词 Drilling process monitoring Specific penetration index Specific energy index Fracture identification
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A new multi-DOF envelope forming process for fabricating spiral bevel gears with back taper tooth
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作者 Xinghui HAN Yanhui WANG +3 位作者 Lin HUA Wuhao ZHUANG Fangyan ZHENG Wei FENG 《Chinese Journal of Aeronautics》 2025年第1期568-585,共18页
Spiral bevel gears are critical transmission components,and are widely used in the aerospace field.This paper proposes a new multi-DOF envelope forming process for fabricating spiral bevel gears.Firstly,the multi-DOF ... Spiral bevel gears are critical transmission components,and are widely used in the aerospace field.This paper proposes a new multi-DOF envelope forming process for fabricating spiral bevel gears.Firstly,the multi-DOF envelope forming principle of spiral bevel gears is proposed.Secondly,the design methods for the envelope tool geometry and movement are proposed based on the envelope geometry and movement relationships.Thirdly,the metal flow and tooth filling laws are revealed through 3D FE simulation of the multi-DOF envelope forming process of a typical spiral bevel gear.Fourthly,a new method for separating the envelope tool and the formed spiral bevel gear with back taper tooth is proposed to avoid their interference.Finally,experiments on multi-DOF envelope forming of this typical spiral bevel gear are conducted using new heavy load multi-DOF envelope forming equipment.The simulation and experimental results show the feasibility of the proposed multi-DOF envelope forming process for fabricating spiral bevel gears with back taper tooth and the corresponding process design methods. 展开更多
关键词 Multi-DOF envelope forming Spiral bevel gear Back taper tooth Metal flow process design
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Towards a blank design method for manufacturing big-tapered profiled ring disk by spinning-rolling process
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作者 Xuechao LI Lianggang GUO +1 位作者 Xiaoqing CHEN Heng LI 《Chinese Journal of Aeronautics》 2025年第1期70-86,共17页
The big-tapered profiled ring disk is a key component of engines for rockets and missiles.A new forming technology,as called spinning-rolling process,has been proposed previously for the high performance,high efficien... The big-tapered profiled ring disk is a key component of engines for rockets and missiles.A new forming technology,as called spinning-rolling process,has been proposed previously for the high performance,high efficiency and low-cost manufacturing of the component.Blank design is the key part of plastic forming process design.For spinning-rolling process,the shape and size of the blank play a crucial role in process stability,deformation behavior and dimensional accuracy.So this work proposes a blank design method to determine the geometry structure and sizes of the blank.The mathematical model for calculating the blank size has been deduced based on volume conservation and neutral layer length invariance principle.The FE simulation and corresponding trial production of an actual big-tapered profiled ring disk show that the proposed blank design method is applicative.In order to obtain a preferred blank,the influence rules of blank size determined by different deformation degrees(rolling ratio k)on the spinning-rolling process are revealed by comprehensive FE simulations.Overall considering the process stability,circularity of the deformed ring disk and forming forces,a reasonable range of deformation degree(rolling ratio k)is recommended for the blank design of the new spinning-rolling process. 展开更多
关键词 Blank design method Spinning-rolling process Big-tapered profiled ring disk Rolling ratio Intelligent FE simulation
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Process Simulate软件在自动化生产线安装调试课程中的应用
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作者 骆峰 杨帆 +1 位作者 胡菡 李智 《工业控制计算机》 2024年第12期37-38,41,共3页
针对自动化生产线安装调试课程的实践教学难题提出了使用仿真软件进行虚拟装调的方案。介绍了如何使用Process Simulate软件对自动化生产线进行虚拟装调。实践证明,使用Process Simulate软件能够有效提高自动化生产线安装调试课程的实... 针对自动化生产线安装调试课程的实践教学难题提出了使用仿真软件进行虚拟装调的方案。介绍了如何使用Process Simulate软件对自动化生产线进行虚拟装调。实践证明,使用Process Simulate软件能够有效提高自动化生产线安装调试课程的实践教学效果。 展开更多
关键词 process Simulate软件 自动化生产线 虚拟装调
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基于Arduino与Processing的心率检测计设计研究 被引量:1
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作者 臧红波 华拓 管志岳 《家电维修》 2024年第3期74-76,共3页
随着社会经济的高速发展,人们的物质生活也有了极大的提高,但同时也伴随着各种疾病的到来,身体健康已经成为人们普遍关注的焦点,因此,心率检测仪、血压计、血糖仪等各种家用医疗监测仪器已经逐渐融入日常生活。心脏病是人们难以预防的... 随着社会经济的高速发展,人们的物质生活也有了极大的提高,但同时也伴随着各种疾病的到来,身体健康已经成为人们普遍关注的焦点,因此,心率检测仪、血压计、血糖仪等各种家用医疗监测仪器已经逐渐融入日常生活。心脏病是人们难以预防的突发致命疾病之一,本文介绍的是一款基于Arduino【是基于易用硬件和软件的原型开源平台,包由可编程的电路板(简称微控制器),以及集成开发环境(称为Arduino IDE)的现成软件组成】Processing(开源编程语言,包括编辑器、编译器、展示器)的简易心率检测计系统,其功能实用、操作简单,可以测量心率,当超出正常心率范围时及时预警,是一款便携的实时心率测试仪。 展开更多
关键词 Arduino processing 心率检测计 设计研究
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Synergistic removal of nitrogen monoxide by non-thermal plasma and catalyst simultaneously 被引量:6
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作者 YU Gang YU Qi +1 位作者 ZENG Ke-si ZHAI Xiao-dong 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2005年第5期846-848,共3页
An experimental system of De-NO with plasma-catalyst(Cu zeolite) was established to investigate the differences between De- NO with plasma-catalyst and De-NO only with plasma, to provide the instruction for selectin... An experimental system of De-NO with plasma-catalyst(Cu zeolite) was established to investigate the differences between De- NO with plasma-catalyst and De-NO only with plasma, to provide the instruction for selecting appropriate catalyst and operating condition, The characteristics of De-NO with plasma and De-NO with plasma-catalyst were investigated comparatively by experiments. The experimental results show that De-NO with plasma-catalyst has high NO removal rate; Cu zeolite is an effective catalyst which can promote NO removal rate in plasma remarkably; De-NO with plasma-catalyst should be operated at low temperature and the temperature has opposite effects on the function of catalvst and plasma; water vapor and O2 can increase the NO removal rate. 展开更多
关键词 nitrogen monoxide( NO) synergistic removal non-thermal plasma CATALYST De-NO
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Simultaneous removal of NO and SO_2 from dry gas stream using non-thermal plasma 被引量:8
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作者 YU Qi YANG Hong-min +2 位作者 ZENG Ke-si ZHANG Zhen-wei YU Gang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2007年第11期1393-1397,共5页
In order to investigate the feasibility of sequential removal NO and SO2 using non-thermal plasma and adsorbent simultaneously, the removal of NO and SO2 from dry gas stream (NO/SO2/N2/O2) with very little O2 using ... In order to investigate the feasibility of sequential removal NO and SO2 using non-thermal plasma and adsorbent simultaneously, the removal of NO and SO2 from dry gas stream (NO/SO2/N2/O2) with very little O2 using non-thermal plasma was investigated using a coaxial dielectric barrier discharge. Comparative experiments were carried out in the dry gas stream with and without Ar respectively at O2 concentration of 0.1%. The results showed that NO could be removed remarkably and it would be enhanced in the presence of Ar in the dry gas stream. It seems that SO2 could not be removed unless there is Ar in the dry gas stream. The mechanism of removal of NO and SO2 in the dry gas stream was discussed. 展开更多
关键词 NO SO2 non-thermal plasma dry gas stream simukaneous removal
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Study on purification technology of polyacrylamide wastewater by non-thermal plasma 被引量:9
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作者 Junfeng RONG Kaixun ZHU Minggong CHEN 《Plasma Science and Technology》 SCIE EI CAS CSCD 2019年第5期66-72,共7页
In this work, non-thermal plasma has been applied to treat polyacrylamide(PAM) wastewater.We have investigated the influence of the rule of PAM wastewater initial pH, solution concentration and discharge time, disch... In this work, non-thermal plasma has been applied to treat polyacrylamide(PAM) wastewater.We have investigated the influence of the rule of PAM wastewater initial pH, solution concentration and discharge time, discharge voltage on chemical oxygen demand(COD)degradation rate. At the same time, the effect of pH and discharge time on the viscosity removal rate of PAM solution was also studied. Then, the effect of pH on the viscosity removal rate of1.0 gl-1 PAM solution was studied separately. Through orthogonal test, the factors affecting the COD degradation rate of PAM wastewater were determined as follows: discharge time > discharge voltage > solution concentration > wastewater initial pH. The COD highest removal rate of PAM wastewater reached 85.74%, when the optimal conditions are as follows:discharge voltage 40 k V, discharge time 5 h, solution concentration 1.0 gl-1, pH 1.5. This research provides some basic data and new theoretical basis for PAM wastewater purification. 展开更多
关键词 non-thermal plasma POLYACRYLAMIDE COD degradation RATE VISCOSITY removal RATE DISCHARGE voltage
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Sterilization of Staphylococcus Aureus by an Atmospheric Non-Thermal Plasma Jet 被引量:3
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作者 刘小虎 洪枫 +2 位作者 郭颖 张菁 石建军 《Plasma Science and Technology》 SCIE EI CAS CSCD 2013年第5期439-442,共4页
An atmospheric non-thermal plasma jet was developed for sterilizing the Staphylococcus aureus (S. aureus). The plasma jet was generated by dielectric barrier discharge (DBD), which was characterized by electrical ... An atmospheric non-thermal plasma jet was developed for sterilizing the Staphylococcus aureus (S. aureus). The plasma jet was generated by dielectric barrier discharge (DBD), which was characterized by electrical and optical diagnostics. The survival curves of the bacteria showed that the plasma jet could effectively inactivate 10 6 cells of S. aureus within 120 seconds and the sterilizing efficiency depended critically on the discharge parameter of the applied voltage. It was further confirmed by scanning electron microscopy (SEM) that the cell morphology was seriously damaged by the plasma treatment. The plasma sterilization mechanism of S. aureus was attributed to the active species of OH, N 2 + and O, which were generated abundantly in the plasma jet and characterized by OES. Our findings suggest a convenient and low-cost way for sterilization and inactivation of bacteria. 展开更多
关键词 non-thermal plasma jet atmospheric pressure STERILIZATION
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Non-thermal Plasma Suppresses Bacterial Colonization on Skin Wound and Promotes Wound Healing in Mice 被引量:4
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作者 俞莺 谭明 +9 位作者 陈宏翔 吴志洪 许莉 李娟 曹经江 杨寅生 肖学敏 连昕 卢新培 涂亚庭 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2011年第3期390-394,共5页
The present study evaluated the effect of non-thermal plasma on skin wound healing in BalB/c mice.Two 6-mm wounds along the both sides of the spine were created on the back of each mouse(n=80) by using a punch biops... The present study evaluated the effect of non-thermal plasma on skin wound healing in BalB/c mice.Two 6-mm wounds along the both sides of the spine were created on the back of each mouse(n=80) by using a punch biopsy.The mice were assigned randomly into two groups,with 40 animals in each group:a non-thermal plasma group in which the mice were treated with the non-thermal plasma;a control group in which the mice were left to heal naturally.Wound healing was evaluated on postoperative days(POD) 4,7,10 and 14(n=5 per group in each POD) by percentage of wound closure.The mice was euthanized on POD 1,4,7,10,14,21,28 and 35(n=1 in each POD).The wounds were removed,routinely fixed,paraffin-embedded,sectioned and HE-stained.A modified scoring system was used to evaluate the wounds.The results showed that acute inflammation peaked on POD 4 in non-thermal plasma group,earlier than in control group in which acute inflammation reached a peak on POD 7,and the acute inflammation scores were much lower in non-thermal group than in control group on POD 7(P0.05).The amount of granular tissue was greater on POD 4 and 7 in non-thermal group than in control group(P0.05).The re-epithelialization score and the neovasularization score were increased significantly in non-thermal group when compared with control group on POD 7 and 10(P0.05 for all).The count of bacterial colonies was 103 CFU/mL on POD 4 and 20 CFU/mL on POD 7,significantly lower than that in control group(109 CFU/mL on POD 4 and 1012 CFU/mL on the POD 7)(P0.05).It was suggested that the non-thermal plasma facilitates the wound healing by suppressing bacterial colo-nization. 展开更多
关键词 non-thermal plasma wound healing BalB/c mice bacterial colonization
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Non-thermal ablation of rabbit liver VX2 tumor by pulsed high intensity focused ultrasound with ultrasound contrast agent:Pathological characteristics 被引量:6
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作者 Cheng-Wen Zhou Fa-Qi Li +3 位作者 Yan Qin Chun-Mei Liu Xiao-Lin Zheng Zhi-Biao Wang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第43期6743-6747,共5页
AIM: To investigate the pathological characteristics of non-thermal damage induced by pulsed high intensity focused ultrasound (PHIFU) combined with ultrasound contrast agent (UCA), SonoVue (Bracco SpA, Milan, I... AIM: To investigate the pathological characteristics of non-thermal damage induced by pulsed high intensity focused ultrasound (PHIFU) combined with ultrasound contrast agent (UCA), SonoVue (Bracco SpA, Milan, Italy) in rabbit liver VX2 tumor. METHODS: Liver VX2 tumor models were established in 20 rabbits, which were divided randomly into PHIFU combined with ultrasound contrast agent group (PHIFU + UCA group) and sham group. In the PHIFU + UCA group, 0.2 mL of SonoVue was injected intravenously into the tumor, followed by ultrasound exposure of Isp 5900 W/cm^2. The rabbits were sacrificed one day after ultrasound exposure. Specimens of the exposed tumor tissues were obtained and observed pathologically under light microscope and transmission electron microscope. The remaining tumor tissues were sent for 2,3,5-Triphenyltetrazolium chloride (TTC) staining. RESULTS: Before Trc staining, tumor tissues in both the sham and the PHIFU + UCA groups resembled gray fish meat, After TIC staining, the tumor tissues were uniformly stained red, with a clear boundary between tumor tissue and normal tissue, Histological examination showed signs of tumor cell injury in PHIFU + UCA group, with cytoplasmic vacuoles of various sizes, chromatin margination and karyopyknosis. Electron microscopic examination revealed tumor cell volume reduction, karyopyknosis, chromatin margination, intercellular space widening, the presence of high electro'n-density apoptotic bodies and vacuoles in cytoplasm. CONCLUSION: The non-thermal effects of PHIFU combined with UCA can be used to ablate rabbit liver VX2 tumors. 展开更多
关键词 Pulsed high intensity focused ultrasound Ultrasound contrast agent non-thermal effects Rabbitliver VX2 tumors HISTOPATHOLOGY
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Non-thermal effects of 0.1 THz radiation on intestinal alkaline phosphatase activity and conformation 被引量:2
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作者 Xin-Xin Zhang Ming-Xia He +4 位作者 Yu Chen Cheng Li Jin-Wu Zhao Peng-Fei Wang Xin Peng 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第12期383-388,共6页
Alkaline phosphatase(ALP) plays an integral role in the metabolism of liver and development of the skeleton in humans. To date, the interactions between different-duration terahertz(THz) radiation and ALP activities, ... Alkaline phosphatase(ALP) plays an integral role in the metabolism of liver and development of the skeleton in humans. To date, the interactions between different-duration terahertz(THz) radiation and ALP activities, as well as the influence mechanism are still unclear. In this study, using the para-nitro-phenyl-phosphate(p NPP) method, we detect changes in ALP activities during 40-minute THz radiation(0.1 THz, 13 m W/cm^2). It is found that the activity of ALP decreases in the first 25 min, and subsequently increases in the later 15 min. Compared with the activity of ALP being heated, the results suggest that short-term terahertz radiation induces a decrease in enzyme activity through the non-thermal mechanism. In order to explore the non-thermal effects of THz radiation on ALP, we focus on the impacts of 0.1 THz radiation for 20 min on the activity of ALP in different concentrations. The results reveal that the activity of ALP decreases significantly after exposure to THz radiation. In addition, it could be deduced from fluorescence, ultraviolet-visible(UV-vis), and THz spectra results that THz radiation has induced changes in ALP structures. Our study unlocks non-thermal interactions between THz radiation and ALP, as well as suggests that THz spectroscopy is a promising technique to distinguish ALP structures. 展开更多
关键词 THz radiation alkaline phosphatase non-thermal effects SPECTROSCOPY CONFORMATIONS
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