Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and...Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and shape.The majority of crown models are static models based on tree size and stand characteristics from temporary sample plots,but crown dynamic models has seldom been constructed.Therefore,this study aimed to develop height to crown base(HCB)and crown length(CL)dynamic models using the branch mortality technique for a Korean larch plantation.The nonlinear mixed-eff ects model with random eff ects,variance functions and correlation structures,was used to build HCB and CL dynamic models.The data were obtained from 95 sample trees of 19 plots in Meng JiaGang forest farm in Northeast China.The results showed that HCB progressively increases as tree age,tree height growth(HT growth)and diameter at breast height growth(DBH growth).The CL was increased with tree age in 20 years ago,and subsequently stabilized.HT growth,DBH growth stand basal area(BAS)and crown competition factor(CCF)signifi cantly infl uenced HCB and CL.The HCB was positively correlated with BAS,HT growth and DBH growth,but negatively correlated with CCF.The CL was positively correlated with BAS and CCF,but negatively correlated with DBH growth.Model fi tting and validation confi rmed that the mixed-eff ects model considering the stand and tree level random eff ects was accurate and reliable for predicting the HCB and CL dynamics.However,the models involving adding variance functions and time series correlation structure could not completely remove heterogeneity and autocorrelation,and the fi tting precision of the models was reduced.Therefore,from the point of view of application,we should take care to avoid setting up over-complex models.The HCB and CL dynamic models in our study may also be incorporated into stand growth and yield model systems in China.展开更多
Mixed-effects models,also called random-effects models,are a regression type of analysis which enables the analyst to not only describe the trend over time within each subject,but also to describe the variation among ...Mixed-effects models,also called random-effects models,are a regression type of analysis which enables the analyst to not only describe the trend over time within each subject,but also to describe the variation among different subjects.Nonlinear mixed-effects models provide a powerful and flexible tool for handling the unbalanced count data.In this paper,nonlinear mixed-effects models are used to analyze the failure data from a repairable system with multiple copies.By using this type of models,statistical inferences about the population and all copies can be made when accounting for copy-to-copy variance.Results of fitting nonlinear mixed-effects models to nine failure-data sets show that the nonlinear mixed-effects models provide a useful tool for analyzing the failure data from multi-copy repairable systems.展开更多
Nonlinear mixed effects model（NLMEM） is based on the relationship between the fixed and random effects in the regression function.The NLMEM has a competitive advantage in analyzing repeated measures data,the longitu...Nonlinear mixed effects model（NLMEM） is based on the relationship between the fixed and random effects in the regression function.The NLMEM has a competitive advantage in analyzing repeated measures data,the longitudinal data and multilevel data.This paper chose two kinds of two-level nonlinear mixed model to analyze basal area growth for Chinese Fir（Cunninghamia lanceolata）. Model 1 is a general two-level NLMEM and Model 2 is based on Model 1 to further consider the fixed effects parameters changes with a specific factor. Firstly,through the analysis of these two models, this paper defined the basic model to build the two-level NLMEM.Secondly,665 kinds of models derived from Model 1 and 2 703 kinds of models derived from Model 2 were calculated and compared. The results showed that:for Model 1,there were 57 kinds of models converging,and when the formal parameter b<sub>0</sub> considered the block effects and plot effects,b<sub>1</sub> and b<sub>4</sub> only considered the block effects, the model fitted the best;and for Model 2,there were 24 kinds of model converging,and when the formal parameter bs considered the block effects and plot effects,b<sub>1</sub> only considered block effects and the fixed effects b<sub>0</sub> changed with any level of block level, Model 2 fitted the best.Finally,by comparing the traditional nonlinear regression model,Model 1 and Model 2,the results showed that Model 1 and Model 2 fitted better than the traditional nonlinear regression, and Model 2 was best fitting model.展开更多
Nonlinear mixed effects model(NLMEM) is built on the relationship of the fixed and random effects in the regression function.The NLMEM has an obvious comparative advantage in analyzing the longitudinal data,repeated m...Nonlinear mixed effects model(NLMEM) is built on the relationship of the fixed and random effects in the regression function.The NLMEM has an obvious comparative advantage in analyzing the longitudinal data,repeated measures data and multilevel data.Two-level NLMEM is used to analyze the dominant height for Chinese fir (Cunninghamia lanceolata).The authors outline the two-level NLMEM and introduce the parameters estimation method of the model.Based on five common Richard and Logistic models,the mixed model is built.The modeling data are used to calculate and compare with 19 models derived from each based model,and 5 optimal mixed models are built.Compared the 5 optimal mixed models with traditional regression models,it is showed that the two-level NLMEM has a better fitting effect than the regression model.展开更多
A Bayesian analysis of the minimal model was proposed where both glucose and insulin were analyzed simultaneously under the insulin-modified intravenous glucose tolerance test (IVGTT). The resulting model was implemen...A Bayesian analysis of the minimal model was proposed where both glucose and insulin were analyzed simultaneously under the insulin-modified intravenous glucose tolerance test (IVGTT). The resulting model was implemented with a nonlinear mixed-effects modeling setup using ordinary differential equations (ODEs), which leads to precise estimation of population parameters by separating the inter- and intra-individual variability. The results indicated that the Bayesian method applied to the glucose-insulin minimal model provided a satisfactory solution with accurate parameter estimates which were numerically stable since the Bayesian method did not require approximation by linearization.展开更多
基金supported by the National Key Research and Development Program of China(2017YFD0600401)the Fundamental Research Funds for the Central Universities(2572019CP08)
文摘Korean larch(Larix olgensis)is one of the main tree species for aff orestation and timber production in northeast China.However,its timber quality and growth ability are largely infl uenced by crown size,structure and shape.The majority of crown models are static models based on tree size and stand characteristics from temporary sample plots,but crown dynamic models has seldom been constructed.Therefore,this study aimed to develop height to crown base(HCB)and crown length(CL)dynamic models using the branch mortality technique for a Korean larch plantation.The nonlinear mixed-eff ects model with random eff ects,variance functions and correlation structures,was used to build HCB and CL dynamic models.The data were obtained from 95 sample trees of 19 plots in Meng JiaGang forest farm in Northeast China.The results showed that HCB progressively increases as tree age,tree height growth(HT growth)and diameter at breast height growth(DBH growth).The CL was increased with tree age in 20 years ago,and subsequently stabilized.HT growth,DBH growth stand basal area(BAS)and crown competition factor(CCF)signifi cantly infl uenced HCB and CL.The HCB was positively correlated with BAS,HT growth and DBH growth,but negatively correlated with CCF.The CL was positively correlated with BAS and CCF,but negatively correlated with DBH growth.Model fi tting and validation confi rmed that the mixed-eff ects model considering the stand and tree level random eff ects was accurate and reliable for predicting the HCB and CL dynamics.However,the models involving adding variance functions and time series correlation structure could not completely remove heterogeneity and autocorrelation,and the fi tting precision of the models was reduced.Therefore,from the point of view of application,we should take care to avoid setting up over-complex models.The HCB and CL dynamic models in our study may also be incorporated into stand growth and yield model systems in China.
文摘Mixed-effects models,also called random-effects models,are a regression type of analysis which enables the analyst to not only describe the trend over time within each subject,but also to describe the variation among different subjects.Nonlinear mixed-effects models provide a powerful and flexible tool for handling the unbalanced count data.In this paper,nonlinear mixed-effects models are used to analyze the failure data from a repairable system with multiple copies.By using this type of models,statistical inferences about the population and all copies can be made when accounting for copy-to-copy variance.Results of fitting nonlinear mixed-effects models to nine failure-data sets show that the nonlinear mixed-effects models provide a useful tool for analyzing the failure data from multi-copy repairable systems.
文摘Nonlinear mixed effects model（NLMEM） is based on the relationship between the fixed and random effects in the regression function.The NLMEM has a competitive advantage in analyzing repeated measures data,the longitudinal data and multilevel data.This paper chose two kinds of two-level nonlinear mixed model to analyze basal area growth for Chinese Fir（Cunninghamia lanceolata）. Model 1 is a general two-level NLMEM and Model 2 is based on Model 1 to further consider the fixed effects parameters changes with a specific factor. Firstly,through the analysis of these two models, this paper defined the basic model to build the two-level NLMEM.Secondly,665 kinds of models derived from Model 1 and 2 703 kinds of models derived from Model 2 were calculated and compared. The results showed that:for Model 1,there were 57 kinds of models converging,and when the formal parameter b<sub>0</sub> considered the block effects and plot effects,b<sub>1</sub> and b<sub>4</sub> only considered the block effects, the model fitted the best;and for Model 2,there were 24 kinds of model converging,and when the formal parameter bs considered the block effects and plot effects,b<sub>1</sub> only considered block effects and the fixed effects b<sub>0</sub> changed with any level of block level, Model 2 fitted the best.Finally,by comparing the traditional nonlinear regression model,Model 1 and Model 2,the results showed that Model 1 and Model 2 fitted better than the traditional nonlinear regression, and Model 2 was best fitting model.
文摘Nonlinear mixed effects model(NLMEM) is built on the relationship of the fixed and random effects in the regression function.The NLMEM has an obvious comparative advantage in analyzing the longitudinal data,repeated measures data and multilevel data.Two-level NLMEM is used to analyze the dominant height for Chinese fir (Cunninghamia lanceolata).The authors outline the two-level NLMEM and introduce the parameters estimation method of the model.Based on five common Richard and Logistic models,the mixed model is built.The modeling data are used to calculate and compare with 19 models derived from each based model,and 5 optimal mixed models are built.Compared the 5 optimal mixed models with traditional regression models,it is showed that the two-level NLMEM has a better fitting effect than the regression model.
文摘A Bayesian analysis of the minimal model was proposed where both glucose and insulin were analyzed simultaneously under the insulin-modified intravenous glucose tolerance test (IVGTT). The resulting model was implemented with a nonlinear mixed-effects modeling setup using ordinary differential equations (ODEs), which leads to precise estimation of population parameters by separating the inter- and intra-individual variability. The results indicated that the Bayesian method applied to the glucose-insulin minimal model provided a satisfactory solution with accurate parameter estimates which were numerically stable since the Bayesian method did not require approximation by linearization.
