A Novel Method of Fabricating Flexible Transparent Conductive Large Area Graphene Film

We fabricate flexible conductive and transparent graphene films on position-emission-tomography substrates and prepare large area graphene films by graphite oxide sheets with the new technical process. The multi-layer graphene oxide sheets can be chemically reduced by HNO3 and HI to form a highly conductive graphene film on a substrate at lower temperature. The reduced graphene oxide sheets show a high conductivity sheet with resistance of 476Ω/sq and transmittance of 76% at 550nm （6 layers）. The technique used to produce the transparent conductive graphene thin film is facile, inexpensive, and can be tunable for a large area production applied for electronics or touch screens.

Novel method of primary endoscopic realignment for high-grade posterior urethral injuries:A case report

BACKGROUND A male urethral disruption injury is a urological emergency.Primary endoscopic realignment(PER)refers to reestablishment of urethral alignment via indwelling urethral catheter by cystoscope,which is recommended as the optimal emergent treatment approach for reducing the likelihood of complications following injury.However,the prior literature suggests the success rate of PER to be relatively low due to complicated urethral disruption.We report a modified PER approach that serves to improve both the success rate and safety of the treatment.CASE SUMMARY A 19-year-old male patient presented with multiple pelvic fractures and complete urethral disruption following a high-velocity traffic accident.The patient’s abdominal computed tomography and retrograde urethrography results revealed complete urethral disruption at the bulbar urethra,with hematoma and contrast medium extravasation that extended into the extraperitoneal space.The conventional retrograde PER by cystoscope failed due to severe disruption and considerable hematoma.Modified simultaneous antegrade and retrograde PER was performed by means of semi-rigid ureteroscopy via a suprapubic Foley catheter and cystoscopy via the external urethra.An antegrade guidewire was passed through the bladder neck and then pulled out through the external urethral meatus with a cystoscope.Urethral continuity was achieved after a 16-Fr silicone Foley catheter was indwelled into the bladder along the guidewire.The patient recovered well,achieving voiding continence and avoiding further operation for urethral stricture.CONCLUSION Modified PER via suprapubic Foley catheter represents a promising and safe treatment approach in patients with posterior urethral injuries.

Analytical Treatment of the Evolutionary (1 + 1)-Dimensional Combined KdV-mKdV Equation via the Novel (G'/G)-Expansion Method

The novel (G'/G)-expansion method is a powerful and simple technique for finding exact traveling wave solutions to nonlinear evolution equations (NLEEs). In this article, we study explicit exact traveling wave solutions for the (1 + 1)-dimensional combined KdV-mKdV equation by using the novel (G'/G)-expansion method. Consequently, various traveling wave solutions patterns including solitary wave solutions, periodic solutions, and kinks are detected and exhibited.

An Experimental Method to Read Novels Without Literary Criticism

Though novel reading is a common experience to everybody,little has been researched to help average readers to understand a novel.In practice,there are two ways for them to understand a novel:one is to use literary criticism theories and the other is to refer to professional critics'criticism directly.However,the trouble is that the two methods are either time-consuming or far from convincing.In this paper,an experimental reading method is discussed to help average readers enhance reading experience.It aims at reaching the goal of reading without criticism,which,through making clear the aim of reading,putting main focus on the story only,will help readers to have a better understanding of reading.

A Novel Real-Time State-of-Health and State-of-Charge Co-Estimation Method for LiFePO_4 Battery

The state of charge （SOC） and state of health （SOH） are two of the most important parameters of Li-ion batteries in industrial production and in practical applications. The real-time estimation for these two parameters is crucial to realize a safe and reliable battery application. However, this is a great problem for LiFePO4 batteries due to the large constant potential plateau in the charge/discharge process. Here we propose a combined SOC and SOH co-estimation method based on the experimental test under the simulating electric vehicle working condition. A first-order resistance-capacitance equivalent circuit is used to model the battery cell, and three parameter values, ohmic resistance （Rs）, parallel resistance （Rp） and parallel capacity （Cp）, are identified from a real-time experimental test. Finally we find that Rp and Cp could be utilized to make a judgement on the SOIl. More importantly, the linear relationship between Cp and the SOC is established to make the estimation of the SOC for the first time.

A NOVEL METHOD FOR SYNTHESIZING α,α-DISUBSTITUTED α-AMINO ACID——DIALKYLATION OF 2-OXAZOLIN-5-ONE

4,4-Dialkyl-2-oxazolin-5-ones are prepared by one step reaction of 2-oxazolin-5-one with the magnesium methyl carbonate(MMC)and alkyIhalides.It is a novel and convenient method for synthesis of α, Υ-disubstitutcd α-amino acid by hydrolysis of 4,4-dialkyl-2-oxazolin-5-ones.

A NOVEL POLYMER ENZYME LINKED IMMUNOASSAY METHOD AND ITS APPLICATIONS

During the course of study, we found that both poly (N-isopropylacrylamide ) (PNIP) and PNIP-Ab (enzyme-labelled antibody)could be adhere tightly to a cellulose acetale-nitrate membrane, and that the retention of PNIP-Ab on the membrane increased over 30-fold when compared with the unconjugated Ab.Thus we used this characteristic to develop a novel immunoassay method-polymer enzyme linked immunoassay method: homogeneous antigen-antibody reaction and heterogeneous separation process. When applied for detection of human serum HBsAg, this immunoassay system can detect as little as 1 ng/ml of human serum HBsAg.

Local Discontinuous Galerkin Methods with Novel Basis for Fractional Diffusion Equations with Non-smooth Solutions

In this paper,we develop novel local discontinuous Galerkin(LDG)methods for fractional diffusion equations with non-smooth solutions.We consider such problems,for which the solutions are not smooth at boundary,and therefore the traditional LDG methods with piecewise polynomial solutions suffer accuracy degeneracy.The novel LDG methods utilize a solution information enriched basis,simulate the problem on a paired special mesh,and achieve optimal order of accuracy.We analyze the L2 stability and optimal error estimate in L2-norm.Finally,numerical examples are presented for validating the theoretical conclusions.

Influence of in vitro Methods, Receptor Fluids on Percutaneous Absorption and Validation of a Novel in vitro Method

In vitro experiment using excised skin has been valuable for studying the mechanism of percutaneous absorption. Based on previously established static diffusion cell system in this laboratory, a novel model-peifused glass diffusion cell system is desboed. The results of initial comporative study on percutaneous absorption between glass perfused diffusion cell and static diffusion cell, ih vitro and in vivo permeation as well as factors affecting permeation with seven radiolabelled chemicals are presented. The results demonstrate that the peifused diffusion cell system, which used a perfusion nuid betow the suiface of skin to take up the materials which penetrated the skin, is more similar to physiologic condition,convenient and automatic than that of the static cell. It well predicts the in vivo percutaneous absorption if appropriate areptor fluid is chosen. The results also show that the selection of receptor fluid is critical for in vitro permeation of chemicals with different soubility

A NOVEL SYNTHETIC METHOD AND STRUCTURE OF TETRAKIS(BENZOATE)BIS(TRIPHENYLPHOSPHINE OXIDE)DICOPPER(II).OXIDATIVE ADDITION OF DIBENZOYL ON METALLIC COPPER

Dibenzoyl peroxide undergoes oxidative addition on metallic copper with triphenylphosphine in a mixed solvent(acetone,dichloromethane and trichloromethane),and affords the binuclear copper complex (Cu(C_6H_5COO)_2(OPPh_3))_2.Crystals are monoclinic,space group A_2/a,with cell parameters,a=24.337(3),b=10.566(1),c=21.579(2),β= 93.18(1)°, V=5540(1)~3,Z=4,R=0.042,and Rw=0.044 for 5872 observed reflections. Each copper ion is coordinated by four bridging benzoato ligands and one triphenylphosphine oxide group to form binuclear complexes.

Naming methods and intention research in English novels

Names are unique phenomenon in human society. People from different countries all have their only names, which generally consist of the first name and the last name. Not only in reality, but also in literary works, they all have their unique names, but the naming methods and intention are different. This paper emphasizes the naming methods and intention in English novels. The names of English novels usually have a richer culture, it embodies the character traits and characters in the novel, such as the outcome of their fate. Therefore, the research of the cultural intention of English novels and translating names accurately is of great significance for literary translation, which also plays an important role in the East-West cultural exchange.

A Novel Method for Separation of Tungsten and Molybdenum

Research on the separation of tungstenand molybdenum is of importance as it is a ba-sic problem in the metallurgy and industry oftungsten.Traditional methods for the separa-tion include precipitation with sulfides andsolvent extraction.There are,however,certaindisadvantages for these methods.A novelmethod was developed based on another

AB036. Pulsatile choroidal blood flow (PCBF) in the glaucoma spectrum-preliminary results obtained with a novel optical method

Background:Decrease of ocular blood flow has been linked to the pathogenesis of ocular diseases such as glaucoma and age-related macular degeneration.Current methods that measure the pulsatile blood flow have major limitations,including the assumption that ocular rigidity is the same in all eyes.Our group has recently developed a new method to measure the pulsatile choroidal volume change by direct visualization of the choroid with OCT imaging and automated segmentation.Our goal in this study is to describe the distribution of PCBF in a healthy Caucasian population.Methods:Fifty-one subjects were recruited from the Maisonneuve-Rosemont Hospital Ophthalmology Clinic and underwent PCBF measurement in one eye.The distribution of PCBF in healthy eyes was assessed.Results:The distribution of PCBF among the healthy eyes was found to be 3.94±1.70µL with this technique.Conclusions:This study demonstrates the normal range of PCBF values obtained in a healthy Caucasian population.This technique could be used for further investigation of choroid pulsatility and to study glaucoma pathophysiology.

Exact Traveling Wave Solutions for the (1 + 1)-Dimensional Compound KdVB Equation via the Novel (G'/G)-Expansion Method

In this work, while applying a new and novel (G'/G)-expansion version technique, we identify four families of the traveling wave solutions to the (1 + 1)-dimensional compound KdVB equation. The exact solutions are derived, in terms of hyperbolic, trigonometric and rational functions, involving various parameters. When the parameters are tuned to special values, both solitary, and periodic wave models are distinguished. State of the art symbolic algebra graphical representations and dynamical interpretations of the obtained solutions physics are provided and discussed. This in turn ends up revealing salient solutions features and demonstrating the used method efficiency.

Nonlinear Algebraic Equations Solved by an Optimal Splitting-Linearizing Iterative Method

How to accelerate the convergence speed and avoid computing the inversion of a Jacobian matrix is important in the solution of nonlinear algebraic equations(NAEs).This paper develops an approach with a splitting-linearizing technique based on the nonlinear term to reduce the effect of the nonlinear terms.We decompose the nonlinear terms in the NAEs through a splitting parameter and then linearize the NAEs around the values at the previous step to a linear system.Through the maximal orthogonal projection concept,to minimize a merit function within a selected interval of splitting parameters,the optimal parameters can be quickly determined.In each step,a linear system is solved by the Gaussian elimination method,and the whole iteration procedure is convergent very fast.Several numerical tests show the high performance of the optimal split-linearization iterative method(OSLIM).

基于降方差采样策略的随机重构法

在随机重构法的采样过程中,每个结构特征需要的采样数量是不相等且变化的。为了将拉丁超立方采样用于降低随机重构模型的方差,基于随机重构法采样过程的特征和拉丁超立方采样原理,提出了适用于随机重构法的新型拉丁超立方采样方法,探究了在多种分子数量设定情况下应用该方法对随机重构模型的方差和精度的影响。结果表明,应用该方法能够显著降低随机重构模型的方差,提高模型的精度,在分子数量为1000~50000范围内,新模型的标准差相较传统模型降低了71.36%~74.53%,目标函数值降低了1.69%~13.82%。综合模型精度和模拟过程的运算开销,选择4000~6000作为新模型最优的分子数量设定。

非洲猪瘟检测方法研究进展

非洲猪瘟(ASF)是由非洲猪瘟病毒(ASFV)引起的猪的一种急性、热性、高度接触性传染病。ASF疫情的暴发,严重威胁全球生猪养殖业安全,给全球造成巨大的经济损失。目前尚未开发出安全有效的ASF疫苗,因此,及时、准确的ASF实验室诊断成为疫情防控的重要手段。ASF现有检测方法包括血清学检测、聚合酶链式反应(PCR)、等温扩增技术和规律成簇的间隔短回文重复序列及其相关系统(CRISPR/Cas)等,其中,血清学检测、PCR检测和CRISPR/Cas都需要专业人员和设备,而等温扩增技术受限于单一类型的检测样品,且灵敏度较低,因此ASF现有检测方法无法同时达到灵敏度高,又快速、简便、可用于现场检测的要求。相较之下,ASF新型检测方法可以达到便捷、高效、省时省力以及可以在现场实现快速检测的优势,其中,生物传感器无需专业人员操作,人工智能(AI)可减少人员成本,并可用于疫情的早期监测,基于磁珠的技术无需复杂的设备,微流体技术可实现高通量快速检测,磁流体装置可解决核酸污染的问题。随着科技的进步,基于免疫层析试纸条和各类传感器的ASF新型检测方法将蓬勃发展。本文总结了ASF现有检测方法,并综述了近5年ASF新型检测方法的发展情况,以期对ASF疫情的科学防控提供参考。

低分子质量肝素锂的制备及其体外抗凝血性能评价

以肝素钠粗品为原料,采用超声盐解-阳离子交换转锂-二氧化氯氧化-醇沉-干燥的新型离子交换工艺制备低分子质量肝素锂。采用Box-Behnlen实验对制备工艺条件进行优化。通过FT-IR、UV-Vis、1HNMR、XPS、比旋光度等对产品进行组成、结构和性能表征,考察了其活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)体外抗凝3项指标。结果表明,盐解辅以超声、转锂时锂型树脂交换、ClO_(2)氧化脱色为该工艺改良的3个关键环节。最佳工艺条件下制得肝素锂效价为173.3 IU/mg,锂质量分数为3.6%,比旋光度为+51.422°。自制肝素锂与肝素钠标准品具有高度相似的结构特征,保留了肝素中—OSO_(3)^(-)、—COO^(-)、OH^(-)等活性基团。自制肝素锂展现出较强的体外抗凝血活性,主要通过内源凝性途径和共同途径作用于凝血过程,可作为医用采血器的预置抗凝剂。

Exact solution for thermal vibration of multi-directional functionally graded porous plates submerged in fluid medium

An analytical method for analyzing the thermal vibration of multi-directional functionally graded porous rectangular plates in fluid media with novel porosity patterns is developed in this study.Mechanical properties of MFG porous plates change according to the length,width,and thickness directions for various materials and the porosity distribution which can be widely applied in many fields of engineering and defence technology.Especially,new porous rules that depend on spatial coordinates and grading indexes are proposed in the present work.Applying Hamilton's principle and the refined higher-order shear deformation plate theory,the governing equation of motion of an MFG porous rectangular plate in a fluid medium(the fluid-plate system)is obtained.The fluid velocity potential is derived from the boundary conditions of the fluid-plate system and is used to compute the extra mass.The GalerkinVlasov solution is used to solve and give natural frequencies of MFG porous plates with various boundary conditions in a fluid medium.The validity and reliability of the suggested method are confirmed by comparing numerical results of the present work with those from available works in the literature.The effects of different parameters on the thermal vibration response of MFG porous rectangular plates are studied in detail.These findings demonstrate that the behavior of the structure within a liquid medium differs significantly from that within a vacuum medium.Thereby,they offer appropriate operational approaches for the structure when employed in various mediums.