<strong>Backgroun</strong><strong>d</strong><strong>:</strong> Obstructive sleep apnea (OSA) has cardiovascular, neurological, and social complications. Surgical treatment has the p...<strong>Backgroun</strong><strong>d</strong><strong>:</strong> Obstructive sleep apnea (OSA) has cardiovascular, neurological, and social complications. Surgical treatment has the potential to improve airway patency but when and which surgery should be done is a controversy. <strong>Aims and objective<strong>s</strong></strong><strong>:</strong> To estimate the site of obstruction in patients with OSAS and to assess the surgical results of the site (of obstruction) directed surgical treatment.<strong> Methodology: </strong>Twenty patients with OSAS were included in the study with Eight adults and Twelve children. It was a prospective study. All patients were assessed for the airway collapse and surgery was done accordingly. Repeat PSG was done after surgery for success rate after 4 months of follow up. <strong>Result:</strong> 17 patients successfully completed the follow-up. Four (50%) adults and Two (17%) children have grade I or II tonsils while Four (50%) of adults and Ten (83%) children have tonsil size grade III or IV. Seven (88%) adults and one (8%) of the children have adenoid hypertrophy up to grade II. One adult (12%) and nine children (75%) have grade III Adenoid size. Two children (17%) have Adenoid grade IV size. In Four patients retropalatal more than retroglossal collapse was found (50%). One patient (12%) had retroglossal more than retropalatal collapse other one had only retropalatal collapse, and the other one had retroglossal collapse. ESS (Epworth sleepiness scale) decreased postoperatively in both groups. There is a significant change in AHI with the median pre-op AHI being 40.19 to median post-op AHI being 11.35 with a p-value 0.017. Apnea-hypopnea index (AHI) in children pre-operatively was 12.98 (median) changed to 2.15 (median) which is statistically significant. Only one adult patient (12%) is surgically cured while in five patients (63%) surgical success achieved with a surgical success rate of 5/8 (63%). Whereas only one patient is surgically cured 1/8 (13%). Eight patients achieved surgical success with a total success rate of 8/9 (89%). While only two patients achieved surgical cure (23%) among children. Conclusion: The outcome of site-directed surgical treatment is that it is a satisfactory way of treatment of OSAS with an overall success rate of 76%.展开更多
目的通过对阻塞性睡眠呼吸暂停综合征(OSAS)患者C-肽含量及血糖水平检测了解该病患者糖代谢情况及是否存在胰岛素抵抗。方法选择OSAS患者29例及正常人21例,行多导睡眠图(PSG)检查,通过C肽释放(CPRT)试验及口服葡萄糖耐量(OGTT)试验检测C...目的通过对阻塞性睡眠呼吸暂停综合征(OSAS)患者C-肽含量及血糖水平检测了解该病患者糖代谢情况及是否存在胰岛素抵抗。方法选择OSAS患者29例及正常人21例,行多导睡眠图(PSG)检查,通过C肽释放(CPRT)试验及口服葡萄糖耐量(OGTT)试验检测C肽(CP)含量及血糖(GLU)浓度。结果 OSAS患者空腹及服糖后2 h C肽含量及血糖水平均高于正常对照组。结论阻塞性睡眠呼吸暂停综合征患者夜间反复低氧,导致患者糖耐量减低,胰岛素抵抗。展开更多
文摘<strong>Backgroun</strong><strong>d</strong><strong>:</strong> Obstructive sleep apnea (OSA) has cardiovascular, neurological, and social complications. Surgical treatment has the potential to improve airway patency but when and which surgery should be done is a controversy. <strong>Aims and objective<strong>s</strong></strong><strong>:</strong> To estimate the site of obstruction in patients with OSAS and to assess the surgical results of the site (of obstruction) directed surgical treatment.<strong> Methodology: </strong>Twenty patients with OSAS were included in the study with Eight adults and Twelve children. It was a prospective study. All patients were assessed for the airway collapse and surgery was done accordingly. Repeat PSG was done after surgery for success rate after 4 months of follow up. <strong>Result:</strong> 17 patients successfully completed the follow-up. Four (50%) adults and Two (17%) children have grade I or II tonsils while Four (50%) of adults and Ten (83%) children have tonsil size grade III or IV. Seven (88%) adults and one (8%) of the children have adenoid hypertrophy up to grade II. One adult (12%) and nine children (75%) have grade III Adenoid size. Two children (17%) have Adenoid grade IV size. In Four patients retropalatal more than retroglossal collapse was found (50%). One patient (12%) had retroglossal more than retropalatal collapse other one had only retropalatal collapse, and the other one had retroglossal collapse. ESS (Epworth sleepiness scale) decreased postoperatively in both groups. There is a significant change in AHI with the median pre-op AHI being 40.19 to median post-op AHI being 11.35 with a p-value 0.017. Apnea-hypopnea index (AHI) in children pre-operatively was 12.98 (median) changed to 2.15 (median) which is statistically significant. Only one adult patient (12%) is surgically cured while in five patients (63%) surgical success achieved with a surgical success rate of 5/8 (63%). Whereas only one patient is surgically cured 1/8 (13%). Eight patients achieved surgical success with a total success rate of 8/9 (89%). While only two patients achieved surgical cure (23%) among children. Conclusion: The outcome of site-directed surgical treatment is that it is a satisfactory way of treatment of OSAS with an overall success rate of 76%.
文摘目的通过对阻塞性睡眠呼吸暂停综合征(OSAS)患者C-肽含量及血糖水平检测了解该病患者糖代谢情况及是否存在胰岛素抵抗。方法选择OSAS患者29例及正常人21例,行多导睡眠图(PSG)检查,通过C肽释放(CPRT)试验及口服葡萄糖耐量(OGTT)试验检测C肽(CP)含量及血糖(GLU)浓度。结果 OSAS患者空腹及服糖后2 h C肽含量及血糖水平均高于正常对照组。结论阻塞性睡眠呼吸暂停综合征患者夜间反复低氧,导致患者糖耐量减低,胰岛素抵抗。
