[Objective] The aim of this study was to reveal the distribution of rapeseed clubfoot disease in Hubei Province and to assess the yield loss caused by the pathogen, Plasmodiophora brassicae. [Method] Field surveys wer...[Objective] The aim of this study was to reveal the distribution of rapeseed clubfoot disease in Hubei Province and to assess the yield loss caused by the pathogen, Plasmodiophora brassicae. [Method] Field surveys were conducted in Shayang, Dangyang, Zhijiang, Yidu and Changyang of Hubei Province during 2009- 2011. Clubfoot disease of rapeseed samples from the surveyed locations were con- firmed by PCR detection and plants infection experiment. The factors of yield and plot yields influenced by clubroot disease were determined in plot experiment. [Re- salt] Rapeseed clubroots were confirmed in Zhijiang and Dangyang and not found in Shayang and Yidu. Clubroot was found in cruciferous vegetables but not in rapeseed d in Changyang. Infection of P. brassicae significantly decreased of the first effective branch numbers of rapeseed, effective pod number per plant, seed number per pod and 1 000-grain weight. Yield of infected rapeseed decreased by 56.4% over non-infected control. [Conclusion] Rapeseed clubroot disease mainly distributed in Zhijiang and Dangyang of Hubei Province. The disease had an economic impact on rapeseed production.展开更多
The development of accessory breast tissue,which is found anywhere along the milk line,is attributed to the failure of milk line remnants to regress during embryogenesis.Primary tumors may arise from any ectopic breas...The development of accessory breast tissue,which is found anywhere along the milk line,is attributed to the failure of milk line remnants to regress during embryogenesis.Primary tumors may arise from any ectopic breast tissue.Accessory breast cancer occurring concurrently with primary invasive breast cancer is extremely rare.Two such cases were reported in this article.One was a 43-year-old Chinese female who exhibited bilateral breast cancer(invasive ductal carcinoma,not otherwise specified,IDC-NOS) and an accessory breast carcinoma(IDC-NOS) incidentally identified in her left axilla.The ectopic breast tissue in her right axilla presented with adenosis.The patient was surgically treated,followed by postoperative docetaxel epirubicin(TE) chemotherapy.The second case was a 53-year-old Chinese female with bilateral breast cancer(apocrine carcinoma) accompanied by an accessory breast carcinoma(IDC-NOS) in her right axilla that was also incidentally identified.The patient was surgically treated after three doses of cyclophosphamide epirubicin docetaxel(CET) neoadjuvant chemotherapy,followed by adjuvant chemotherapy of the same regimen.展开更多
Up to present,the problem of the evaluation of fault diagnosability for nonlinear systems has been investigated by many researchers.However,no attempt has been done to evaluate the diagnosability of multiple faults oc...Up to present,the problem of the evaluation of fault diagnosability for nonlinear systems has been investigated by many researchers.However,no attempt has been done to evaluate the diagnosability of multiple faults occurring simultaneously for nonlinear systems.This paper proposes a method based on differential geometry theories to solve this problem.Then the evaluation of fault diagnosability for affine nonlinear systems with multiple faults occurring simultaneously is achieved.To deal with the effect of control laws on the evaluation results of fault diagnosability,a design scheme of the evaluation of fault diagnosability is proposed.Then the influence of uncertainties on the evaluation results of fault diagnosability for affine nonlinear systems with multiple faults occurring simultaneously is analyzed.The numerical simulation results are obtained to show the effectiveness of the proposed evaluation scheme of fault diagnosability.展开更多
[Objective] The aim was to study the causes for one large scale of consecutive rainstorm process in the winter of 2010 in Guangxi. [Method] The characteristics and causes of the uncommon persistent heavy rain occurrin...[Objective] The aim was to study the causes for one large scale of consecutive rainstorm process in the winter of 2010 in Guangxi. [Method] The characteristics and causes of the uncommon persistent heavy rain occurring in Guangxi in January, 2010 were analyzed by using synoptic observation data, NCEP 1°×1° per six hours Global Data Assimilation System reanalysis data and satellite image. [Result] The results showed that this persistent heavy rain process was associated with abnormal intensity and the stability of the western pacific subtropical high. The heavy rain was caused by the cloud system maintaining for a long time on the edge of subtropical high. The convergence of the infrequent southeast jet was the primary cause of the uncommon heavy rain. MPV1>0, and MPV2<0 at 700 hPa were the favorable conditions for the heavy rain. The magnitude of MPV1 and MPV2 was equivalent. [Conclusion] The study provided reference for the forecast of the following similar extreme weather.展开更多
In this paper, the distributed synchronization of stochastic coupled neural networks with time-varying delay is concerned via randomly occurring control. We use two Bernoulli stochastic variables to describe the occur...In this paper, the distributed synchronization of stochastic coupled neural networks with time-varying delay is concerned via randomly occurring control. We use two Bernoulli stochastic variables to describe the occurrence of distributed adaptive control and updating law according to certain probabilities. The distributed adaptive control and updating law for each vertex in the network depend on the state information on each vertex’s neighborhood. Based on Lyapunov stability theory, It</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ô</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> differential equations, etc., by constructing the appropriate Lyapunov functional, we study and obtain sufficient conditions for the distributed synchronization of such networks in mean square.展开更多
Inorganic phosphate(Pi) is an essential nutrient to living organisms. It is required as a component of the energy metabolism,kinase/phosphatase signaling and in the formation and function of lipids,carbohydrates and n...Inorganic phosphate(Pi) is an essential nutrient to living organisms. It is required as a component of the energy metabolism,kinase/phosphatase signaling and in the formation and function of lipids,carbohydrates and nucleic acids and,at systemic level,it plays a key role for normal skeletal and dentin mineralization. Pi represents an abundant dietary element and its intestinal absorption is efficient,minimally regulated and typically extends to approximately 70%. Maintenance of proper Pi homeostasis is a critical event and serum Pi level is maintained within a narrow range through an elaborate network of humoral interactions and feedback loops involving intestine,kidney,parathyroid gland and bone,and depends on the activity of a number of hormones,including parathyroid hormone,1,25-dihydroxy vitamin D,and fibroblast growth factor 23 as major regulators of Pi homeostasis. Notably,Pi intake seemingly continues to increase as a consequence of chronic high-phosphorus(P) diets deriving from the growing consumption of highly processed foods,especially restaurant meals,fast foods,and convenience foods. Several recent reports have generated significant associations between high-P intake or high-serum Pi concentration and morbidity and mortality. Many chronic diseases,including cardiovascular diseases,obesity and even cancer have been proposed to be associated with high-P intakes and high-serum Pi concentrations. On the other hand,there is also evidence that Pi can have antiproliferative effects on some cancer cell types,depending on cell status and genetic background and achieve additive cytotoxic effects when combined with doxorubicin,illustrating its potential for clinical applications and suggesting that up-regulating Pi levels at local sites for brief times,might contribute to the development of novel and cheap modalities for therapeutic intervention in some tumours. Overall,the influence of Pi on cell function and the possible relationship to cancer have to be fully understood and investigated further.展开更多
This work aimed to develop a healthier meat product, by improving nutritional properties related to lipid profile, using a Maillard reaction product (MRP) obtained from recycling blood from local slaughterhouses as an...This work aimed to develop a healthier meat product, by improving nutritional properties related to lipid profile, using a Maillard reaction product (MRP) obtained from recycling blood from local slaughterhouses as antioxidant. Soybean oil was used as partial fat replacer and the lipid profile was modified as a decrease in the n6/n3 ratio (11.59 to 9.50), and atherogenic and trombogenic index (from 0.42 to 0.27 and 0.94 to 0.56 respectively) was observed. Beef patties were added with two MRP levels (1% w/w and 3% w/w). Patties with no antioxidants were used as control and patties containing 0.01% w/w of butylhydroxyanisole (BHA) were used as reference. Oxidative stability of refrigerated vacuum-packed patties was evaluated during 15 days of storage. Results showed 3% of MRP as the most appropriate concentration to prevent lipid oxidation with inhibition percentages of 75%, and 9 days as the limit time of chilled storage regarding consumers’ perceptions.展开更多
To the Editor:Transjugularintrahepaticportosystemicshunt(TIPS)isusuallyconsideredthechoiceformanagingcomplicationsofportal hypertensionsuchasrefractoryascites,esophagogastricvariceal bleedingandrecurrentbleedinguncont...To the Editor:Transjugularintrahepaticportosystemicshunt(TIPS)isusuallyconsideredthechoiceformanagingcomplicationsofportal hypertensionsuchasrefractoryascites,esophagogastricvariceal bleedingandrecurrentbleedinguncontrolledwithfirstline treatment.Inrecentyears,TIPShasbeensuccessfullyusedto treat Budd-Chiari syndrome, hepatic hydrothorax, and portal vein thrombosis.One of the key steps during TIPS is the portal vein puncture.展开更多
This paper studies the distributed synchronization control problem of a class of stochastic dynamical systems with time-varying delays and random noise via randomly occurring control. The activation of the distributed...This paper studies the distributed synchronization control problem of a class of stochastic dynamical systems with time-varying delays and random noise via randomly occurring control. The activation of the distributed adaptive controller and the update of the control gain designed in this paper all happen randomly. Based on the Lyapunov stability theory, LaSalle invariance principle, combined with the use of the properties of the matrix Kronecker product, stochastic differential equation theory and other related tools, by constructing the appropriate Lyapunov functional, the criterion for the distributed synchronization of this type of stochastic complex networks in mean square is obtained.展开更多
We investigate the granular flow states in a channel with bottleneck by molecular dynamics simulations.Our study is restricted only on a selected key area rather than on the whole system to focus on the flow propertie...We investigate the granular flow states in a channel with bottleneck by molecular dynamics simulations.Our study is restricted only on a selected key area rather than on the whole system to focus on the flow properties of a single granular state.A random force field is introduced to control the granular temperature.It is also pointed out that the flow rate in the granular flow can be correlated with the pressure,which leads us to carry out a comprehensive study similar to the classical study for general liquid-gas phase transition.Our results show that the dilute flow state and the dense flow state of the granules are similar to the gas state and the liquid state of general substances,respectively,and the properties of phase transition and critical phenomenon are also similar to those occurring in general substances.展开更多
For some repeatedly occurring failure with root cause,the reliability centered maintenance (RCM) can’t deal with them effectively. So,the logic diagram of RCM was improved by combining it with proactive maintenance t...For some repeatedly occurring failure with root cause,the reliability centered maintenance (RCM) can’t deal with them effectively. So,the logic diagram of RCM was improved by combining it with proactive maintenance technology. First,root cause analysis is used to build a key result-cause chain of the repeatedly occur failure. Then,a reasonable link in the chain,which work station is suitable to be monitored and repaired,should be selected. Finally,the corresponding proactive maintenance measure should be adopted to prevent the matter occur on the chain and broken the key result-cause chain,and the repeatedly occur failure is to be prevent at a deeper level or from the root cause. By doing this,a system engineering method comes into being,not only it can determine the needs of preventive maintenance for equipment,but also determine the proactive maintenance needs for equipment. The analysis result of reliability centered maintenance and the analysis result considering proactive maintenance are combined to form a maintenance guideline containing proactive maintenance strategy.展开更多
This paper considers the distribution of technogenic 137Cs and naturally occurring radionuclides:238 U,232 Th and40 R concentrations in soils and 137Cs in atmospheric dry depositions by altitudinal belts of the Aragat...This paper considers the distribution of technogenic 137Cs and naturally occurring radionuclides:238 U,232 Th and40 R concentrations in soils and 137Cs in atmospheric dry depositions by altitudinal belts of the Aragats mountain massif,Republic of Armenia.Undisturbed soil samples were collected at altitudes from 1000 to 3200 m.For the determination of geochemical variability,two soil sampling campaigns were undertaken.Atmospheric dry depositions were sampled from five stations at1100-3200 m collected onto organic fiber filters between June and December 2016.137Cs activity was measured using a high-purity Germanium detector coupled to a multichannel analyzer(Canberra).Results indicated that specific activity of 137Cs in soils at 1000 m is495-528 Bq m^-2,andat3200 mis10,500-11,470 Bq m^-2.No correlation observed for 137Cs versus naturally occurring radionuclides,which varies in distribution by altitude.Specific activities of 137Cs in dry atmospheric depositions varies from 1.06 at 846 m to2.37 Bq m^-2 per quarter at 3200 m and increases as the altitude increases.Activities of 137Cs in soil and dry atmospheric deposition correlated significantly,and 137Cs activity in soils and atmospheric dry depositions decrease as the absolute altitude decreases.The 50-year effective dose from exposure to 137Cs fallout varies with altitude from 0.007 to 1.42 m Sv.展开更多
3,5-Dimethoxyhomophthalic acid was synthesized in four steps from 3,5-dimethoxycinnamic acid via a series of reactions including cyclization of 3-(3',5'-dimethoxyphenyl)propionic acid to 5,7-dimethoxy-1-indanone a...3,5-Dimethoxyhomophthalic acid was synthesized in four steps from 3,5-dimethoxycinnamic acid via a series of reactions including cyclization of 3-(3',5'-dimethoxyphenyl)propionic acid to 5,7-dimethoxy-1-indanone and oxidative decomposition of methyl-2-hydroxy-2-[5,7-dimethyoxy-1-oxo-1H-inden-2(3H)-ylidene]acetate to 3,5-dimethoxyhomophthalic acid.The synthesized compounds were characterized by elemental analysis,IR,1H NMR,and MS.The biological evaluation experiments of 3,5-dimthoxyhomophthalic acid and the related synthesized compounds were also carried out.Naturally occurring biologically active isocoumarins were prepared in a single step by the condensation of the homophthalic acid with appropriate acid chlorides.展开更多
plane with the strike of 127°, the dip of 79° and the rake of 171°. The rupture process inversion result of MS=7.9 earthquake shows that the total rupture duration is about 37 s, the scalar moment tenso...plane with the strike of 127°, the dip of 79° and the rake of 171°. The rupture process inversion result of MS=7.9 earthquake shows that the total rupture duration is about 37 s, the scalar moment tensor is M0=0.97 × 1020 N·m. Rupture mainly occurred on the shallow area with 110 km long and 30 km wide, the location in which the rupture initiated is not where the main rupture took place, and the area with slip greater than 0.5 m basically lies within 35 km deep middle-crust under the earth surface. The maximum static slip is 3.6 m. There are two distinct areas with slip larger than 2.0 m. We noticed that when the rupture propagated towards northwest and closed to the area around the MS=7.3 hypocenter, the slip decreased rapidly, which may indicate that the rupture process was stopped by barriers. The consistence of spatial distribution of slip on the fault plane with the distribution of aftershocks also supports that the rupture is a heterogeneous process owing to the presence of barriers.展开更多
1 Geography Location At 16:30 on August 3rd, 2014, Ludian County, Zhaotong City, Yunnan Province (27.1°N, 103.3°E) was hit by Ms 6.5 earthquake, with the maximum intensity is 9 and epicenter depth is aro...1 Geography Location At 16:30 on August 3rd, 2014, Ludian County, Zhaotong City, Yunnan Province (27.1°N, 103.3°E) was hit by Ms 6.5 earthquake, with the maximum intensity is 9 and epicenter depth is around 12 km (Figs. 1 and 2).展开更多
Although congenital sensorineural hearing loss (SHL) in the bilateral cochleae mainly results from genetic abnormalities, chronic SHL progressing in later life is often influenced by systemic immune disturbances, incl...Although congenital sensorineural hearing loss (SHL) in the bilateral cochleae mainly results from genetic abnormalities, chronic SHL progressing in later life is often influenced by systemic immune disturbances, including autoimmunity, chronic inflammation, and immunosenescence. We have investigated the relationship between the inner ear and systemic immunity and reviewed the possibilities to prevent SHL, including autoimmune SHL and age-related SHL. We also demonstrated two lymphocyte populations, interleukin 1 receptor type II (IL-1R2)-positive T cells (T1R2) and naturally occurring regulatory T cells (nTregs) in CD4+ T cells, which increase with aging, suppress host immune function and promote organ degeneration. Alterations in systemic immunity by fewer microbial antigen challenges in the living environment, elimination of immune suppressive lymphocytes, or immune rejuvenation with a reconstituted thymus may contribute not only to renew the cochlear function in SHL, but also to extend the healthy life of functional organs in a vigorous and youthful body, one of humanity’s greatest dreams.展开更多
Entering in the month of November,Zhuhai—the sea-side garden city was full of exitement and activity.Marlboro Zhuhai International Automobile Race and ’96 ChinaInternational Aviation & Aerospace Exhibition were ...Entering in the month of November,Zhuhai—the sea-side garden city was full of exitement and activity.Marlboro Zhuhai International Automobile Race and ’96 ChinaInternational Aviation & Aerospace Exhibition were closedon the 4th and 10th of November respectively.Guests fromvarious places of the world and over 1300 Chinese andforeign news reporters gathered in Zhuhai,and news bulletinswere released through various big medias.Automobile Race,Aviation & Aerospace Exhibition and the closely followedZhuhai International Movie Festival became Zhuhai’s acceler-ated velocity of advancing towards the world!It is said that starting from now and up to the year of2014,China will import 1320 aeroplanes with an amount of100 billion US dollars.Such a huge market is very seldomhappened in the world.President of Boeing Company,Chair-展开更多
happen、occur 和 take place 为同义词,均可表示“发生”。在若干情况下,这三个词可以通过,但它们又各有特点,有些使用上的差异。1.happen:表示事情的发生存在一定的偶然性。What has happened?出什么事了?If anything happens,please ...happen、occur 和 take place 为同义词,均可表示“发生”。在若干情况下,这三个词可以通过,但它们又各有特点,有些使用上的差异。1.happen:表示事情的发生存在一定的偶然性。What has happened?出什么事了?If anything happens,please let me know.不管发生什么事,都请通知我。How did the car accident happen?车祸是怎么发生的?2.展开更多
Reaction products of 2,4,6-tris(4-phenyl-phenoxy)-1,3,5-triazine derived from 4-phenylphenol cyanate ester and phenyl glycidyl ether were analyzed. In addition to an isocyanurate compound and an oxazolidone compound w...Reaction products of 2,4,6-tris(4-phenyl-phenoxy)-1,3,5-triazine derived from 4-phenylphenol cyanate ester and phenyl glycidyl ether were analyzed. In addition to an isocyanurate compound and an oxazolidone compound which were well known as reaction products of cyanate esters and epoxy resins, compounds with hybrid ring structure of cyanurate/isocyanurate were determined. Gibbs free energies of the compound having hybrid ring structure of cyanurate/isocyanurate with two isocyanurate moiety were found to be lower than that of the compound with cyanurate ring structure through calculations. Calculation data supported the existence of hybrid ring structure of cy-anurate/isocyanurate. It was revealed that isomerization from cyanurate to isocyanurate occurs via hybrid ring structure of cyanurate/isocyanurate in the reaction of aryl cyanurate and epoxy.展开更多
基金Supported by the Industry Technology System of Rapeseed in China(nycytx-005)Special Fund for Agro-scientific Research in the Public Interest(201003029)National Key Technology Research and Development Program of the Ministry of Science and Technology of China(2010BAD01B04)~~
文摘[Objective] The aim of this study was to reveal the distribution of rapeseed clubfoot disease in Hubei Province and to assess the yield loss caused by the pathogen, Plasmodiophora brassicae. [Method] Field surveys were conducted in Shayang, Dangyang, Zhijiang, Yidu and Changyang of Hubei Province during 2009- 2011. Clubfoot disease of rapeseed samples from the surveyed locations were con- firmed by PCR detection and plants infection experiment. The factors of yield and plot yields influenced by clubroot disease were determined in plot experiment. [Re- salt] Rapeseed clubroots were confirmed in Zhijiang and Dangyang and not found in Shayang and Yidu. Clubroot was found in cruciferous vegetables but not in rapeseed d in Changyang. Infection of P. brassicae significantly decreased of the first effective branch numbers of rapeseed, effective pod number per plant, seed number per pod and 1 000-grain weight. Yield of infected rapeseed decreased by 56.4% over non-infected control. [Conclusion] Rapeseed clubroot disease mainly distributed in Zhijiang and Dangyang of Hubei Province. The disease had an economic impact on rapeseed production.
基金supported by the National Natural Science Foundation of China(No.30930038)National"973"Program of China(No.2009CB521700+1 种基金2009CB918903)Program for Changjiang Scholars and Innovative Research Team in University(No.IRT0743)
文摘The development of accessory breast tissue,which is found anywhere along the milk line,is attributed to the failure of milk line remnants to regress during embryogenesis.Primary tumors may arise from any ectopic breast tissue.Accessory breast cancer occurring concurrently with primary invasive breast cancer is extremely rare.Two such cases were reported in this article.One was a 43-year-old Chinese female who exhibited bilateral breast cancer(invasive ductal carcinoma,not otherwise specified,IDC-NOS) and an accessory breast carcinoma(IDC-NOS) incidentally identified in her left axilla.The ectopic breast tissue in her right axilla presented with adenosis.The patient was surgically treated,followed by postoperative docetaxel epirubicin(TE) chemotherapy.The second case was a 53-year-old Chinese female with bilateral breast cancer(apocrine carcinoma) accompanied by an accessory breast carcinoma(IDC-NOS) in her right axilla that was also incidentally identified.The patient was surgically treated after three doses of cyclophosphamide epirubicin docetaxel(CET) neoadjuvant chemotherapy,followed by adjuvant chemotherapy of the same regimen.
基金the Natural Science Foundation of Fujian Province,China(2019J05024)the Education Department Foundation of Fujian Province,China(JAT170091).
文摘Up to present,the problem of the evaluation of fault diagnosability for nonlinear systems has been investigated by many researchers.However,no attempt has been done to evaluate the diagnosability of multiple faults occurring simultaneously for nonlinear systems.This paper proposes a method based on differential geometry theories to solve this problem.Then the evaluation of fault diagnosability for affine nonlinear systems with multiple faults occurring simultaneously is achieved.To deal with the effect of control laws on the evaluation results of fault diagnosability,a design scheme of the evaluation of fault diagnosability is proposed.Then the influence of uncertainties on the evaluation results of fault diagnosability for affine nonlinear systems with multiple faults occurring simultaneously is analyzed.The numerical simulation results are obtained to show the effectiveness of the proposed evaluation scheme of fault diagnosability.
基金Supported by Guangxi Zhuang Autonomous Region Meteorological Scientific Research Program (Guangxi Meteorological Science 200725)
文摘[Objective] The aim was to study the causes for one large scale of consecutive rainstorm process in the winter of 2010 in Guangxi. [Method] The characteristics and causes of the uncommon persistent heavy rain occurring in Guangxi in January, 2010 were analyzed by using synoptic observation data, NCEP 1°×1° per six hours Global Data Assimilation System reanalysis data and satellite image. [Result] The results showed that this persistent heavy rain process was associated with abnormal intensity and the stability of the western pacific subtropical high. The heavy rain was caused by the cloud system maintaining for a long time on the edge of subtropical high. The convergence of the infrequent southeast jet was the primary cause of the uncommon heavy rain. MPV1>0, and MPV2<0 at 700 hPa were the favorable conditions for the heavy rain. The magnitude of MPV1 and MPV2 was equivalent. [Conclusion] The study provided reference for the forecast of the following similar extreme weather.
文摘In this paper, the distributed synchronization of stochastic coupled neural networks with time-varying delay is concerned via randomly occurring control. We use two Bernoulli stochastic variables to describe the occurrence of distributed adaptive control and updating law according to certain probabilities. The distributed adaptive control and updating law for each vertex in the network depend on the state information on each vertex’s neighborhood. Based on Lyapunov stability theory, It</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ô</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> differential equations, etc., by constructing the appropriate Lyapunov functional, we study and obtain sufficient conditions for the distributed synchronization of such networks in mean square.
文摘Inorganic phosphate(Pi) is an essential nutrient to living organisms. It is required as a component of the energy metabolism,kinase/phosphatase signaling and in the formation and function of lipids,carbohydrates and nucleic acids and,at systemic level,it plays a key role for normal skeletal and dentin mineralization. Pi represents an abundant dietary element and its intestinal absorption is efficient,minimally regulated and typically extends to approximately 70%. Maintenance of proper Pi homeostasis is a critical event and serum Pi level is maintained within a narrow range through an elaborate network of humoral interactions and feedback loops involving intestine,kidney,parathyroid gland and bone,and depends on the activity of a number of hormones,including parathyroid hormone,1,25-dihydroxy vitamin D,and fibroblast growth factor 23 as major regulators of Pi homeostasis. Notably,Pi intake seemingly continues to increase as a consequence of chronic high-phosphorus(P) diets deriving from the growing consumption of highly processed foods,especially restaurant meals,fast foods,and convenience foods. Several recent reports have generated significant associations between high-P intake or high-serum Pi concentration and morbidity and mortality. Many chronic diseases,including cardiovascular diseases,obesity and even cancer have been proposed to be associated with high-P intakes and high-serum Pi concentrations. On the other hand,there is also evidence that Pi can have antiproliferative effects on some cancer cell types,depending on cell status and genetic background and achieve additive cytotoxic effects when combined with doxorubicin,illustrating its potential for clinical applications and suggesting that up-regulating Pi levels at local sites for brief times,might contribute to the development of novel and cheap modalities for therapeutic intervention in some tumours. Overall,the influence of Pi on cell function and the possible relationship to cancer have to be fully understood and investigated further.
文摘This work aimed to develop a healthier meat product, by improving nutritional properties related to lipid profile, using a Maillard reaction product (MRP) obtained from recycling blood from local slaughterhouses as antioxidant. Soybean oil was used as partial fat replacer and the lipid profile was modified as a decrease in the n6/n3 ratio (11.59 to 9.50), and atherogenic and trombogenic index (from 0.42 to 0.27 and 0.94 to 0.56 respectively) was observed. Beef patties were added with two MRP levels (1% w/w and 3% w/w). Patties with no antioxidants were used as control and patties containing 0.01% w/w of butylhydroxyanisole (BHA) were used as reference. Oxidative stability of refrigerated vacuum-packed patties was evaluated during 15 days of storage. Results showed 3% of MRP as the most appropriate concentration to prevent lipid oxidation with inhibition percentages of 75%, and 9 days as the limit time of chilled storage regarding consumers’ perceptions.
基金supported by President fund of Qingdao Municipal Hospital(ZYZJJ2017116)
文摘To the Editor:Transjugularintrahepaticportosystemicshunt(TIPS)isusuallyconsideredthechoiceformanagingcomplicationsofportal hypertensionsuchasrefractoryascites,esophagogastricvariceal bleedingandrecurrentbleedinguncontrolledwithfirstline treatment.Inrecentyears,TIPShasbeensuccessfullyusedto treat Budd-Chiari syndrome, hepatic hydrothorax, and portal vein thrombosis.One of the key steps during TIPS is the portal vein puncture.
文摘This paper studies the distributed synchronization control problem of a class of stochastic dynamical systems with time-varying delays and random noise via randomly occurring control. The activation of the distributed adaptive controller and the update of the control gain designed in this paper all happen randomly. Based on the Lyapunov stability theory, LaSalle invariance principle, combined with the use of the properties of the matrix Kronecker product, stochastic differential equation theory and other related tools, by constructing the appropriate Lyapunov functional, the criterion for the distributed synchronization of this type of stochastic complex networks in mean square is obtained.
基金Supported by the National Natural Science Foundation of China under Grant Nos 10875166 and 11274355
文摘We investigate the granular flow states in a channel with bottleneck by molecular dynamics simulations.Our study is restricted only on a selected key area rather than on the whole system to focus on the flow properties of a single granular state.A random force field is introduced to control the granular temperature.It is also pointed out that the flow rate in the granular flow can be correlated with the pressure,which leads us to carry out a comprehensive study similar to the classical study for general liquid-gas phase transition.Our results show that the dilute flow state and the dense flow state of the granules are similar to the gas state and the liquid state of general substances,respectively,and the properties of phase transition and critical phenomenon are also similar to those occurring in general substances.
文摘For some repeatedly occurring failure with root cause,the reliability centered maintenance (RCM) can’t deal with them effectively. So,the logic diagram of RCM was improved by combining it with proactive maintenance technology. First,root cause analysis is used to build a key result-cause chain of the repeatedly occur failure. Then,a reasonable link in the chain,which work station is suitable to be monitored and repaired,should be selected. Finally,the corresponding proactive maintenance measure should be adopted to prevent the matter occur on the chain and broken the key result-cause chain,and the repeatedly occur failure is to be prevent at a deeper level or from the root cause. By doing this,a system engineering method comes into being,not only it can determine the needs of preventive maintenance for equipment,but also determine the proactive maintenance needs for equipment. The analysis result of reliability centered maintenance and the analysis result considering proactive maintenance are combined to form a maintenance guideline containing proactive maintenance strategy.
基金a Grant No. 15T-1E061 ‘‘Radioecological Monitoring in the Area of the Republic of Armenia’’ 2015–2017, under support of State Committee of Science to the Ministry of Education and Science RA
文摘This paper considers the distribution of technogenic 137Cs and naturally occurring radionuclides:238 U,232 Th and40 R concentrations in soils and 137Cs in atmospheric dry depositions by altitudinal belts of the Aragats mountain massif,Republic of Armenia.Undisturbed soil samples were collected at altitudes from 1000 to 3200 m.For the determination of geochemical variability,two soil sampling campaigns were undertaken.Atmospheric dry depositions were sampled from five stations at1100-3200 m collected onto organic fiber filters between June and December 2016.137Cs activity was measured using a high-purity Germanium detector coupled to a multichannel analyzer(Canberra).Results indicated that specific activity of 137Cs in soils at 1000 m is495-528 Bq m^-2,andat3200 mis10,500-11,470 Bq m^-2.No correlation observed for 137Cs versus naturally occurring radionuclides,which varies in distribution by altitude.Specific activities of 137Cs in dry atmospheric depositions varies from 1.06 at 846 m to2.37 Bq m^-2 per quarter at 3200 m and increases as the altitude increases.Activities of 137Cs in soil and dry atmospheric deposition correlated significantly,and 137Cs activity in soils and atmospheric dry depositions decrease as the absolute altitude decreases.The 50-year effective dose from exposure to 137Cs fallout varies with altitude from 0.007 to 1.42 m Sv.
基金Supported by Higher Education Commission of Pakistan,the National Basic Research Program of China(No.2003CB114402)the National Natrual Science Foundation of China(No.20672062)the Tianjin Natural Science Foundation(No.07JCYBJC01200).
文摘3,5-Dimethoxyhomophthalic acid was synthesized in four steps from 3,5-dimethoxycinnamic acid via a series of reactions including cyclization of 3-(3',5'-dimethoxyphenyl)propionic acid to 5,7-dimethoxy-1-indanone and oxidative decomposition of methyl-2-hydroxy-2-[5,7-dimethyoxy-1-oxo-1H-inden-2(3H)-ylidene]acetate to 3,5-dimethoxyhomophthalic acid.The synthesized compounds were characterized by elemental analysis,IR,1H NMR,and MS.The biological evaluation experiments of 3,5-dimthoxyhomophthalic acid and the related synthesized compounds were also carried out.Naturally occurring biologically active isocoumarins were prepared in a single step by the condensation of the homophthalic acid with appropriate acid chlorides.
基金The Specialized Funds for National Key Basic Study (G1998040704), the Dual Project of China Earthquake Admini-stration (9691309020301) and National Natural Science Foundation of China (46764010).
文摘plane with the strike of 127°, the dip of 79° and the rake of 171°. The rupture process inversion result of MS=7.9 earthquake shows that the total rupture duration is about 37 s, the scalar moment tensor is M0=0.97 × 1020 N·m. Rupture mainly occurred on the shallow area with 110 km long and 30 km wide, the location in which the rupture initiated is not where the main rupture took place, and the area with slip greater than 0.5 m basically lies within 35 km deep middle-crust under the earth surface. The maximum static slip is 3.6 m. There are two distinct areas with slip larger than 2.0 m. We noticed that when the rupture propagated towards northwest and closed to the area around the MS=7.3 hypocenter, the slip decreased rapidly, which may indicate that the rupture process was stopped by barriers. The consistence of spatial distribution of slip on the fault plane with the distribution of aftershocks also supports that the rupture is a heterogeneous process owing to the presence of barriers.
文摘1 Geography Location At 16:30 on August 3rd, 2014, Ludian County, Zhaotong City, Yunnan Province (27.1°N, 103.3°E) was hit by Ms 6.5 earthquake, with the maximum intensity is 9 and epicenter depth is around 12 km (Figs. 1 and 2).
文摘Although congenital sensorineural hearing loss (SHL) in the bilateral cochleae mainly results from genetic abnormalities, chronic SHL progressing in later life is often influenced by systemic immune disturbances, including autoimmunity, chronic inflammation, and immunosenescence. We have investigated the relationship between the inner ear and systemic immunity and reviewed the possibilities to prevent SHL, including autoimmune SHL and age-related SHL. We also demonstrated two lymphocyte populations, interleukin 1 receptor type II (IL-1R2)-positive T cells (T1R2) and naturally occurring regulatory T cells (nTregs) in CD4+ T cells, which increase with aging, suppress host immune function and promote organ degeneration. Alterations in systemic immunity by fewer microbial antigen challenges in the living environment, elimination of immune suppressive lymphocytes, or immune rejuvenation with a reconstituted thymus may contribute not only to renew the cochlear function in SHL, but also to extend the healthy life of functional organs in a vigorous and youthful body, one of humanity’s greatest dreams.
文摘Entering in the month of November,Zhuhai—the sea-side garden city was full of exitement and activity.Marlboro Zhuhai International Automobile Race and ’96 ChinaInternational Aviation & Aerospace Exhibition were closedon the 4th and 10th of November respectively.Guests fromvarious places of the world and over 1300 Chinese andforeign news reporters gathered in Zhuhai,and news bulletinswere released through various big medias.Automobile Race,Aviation & Aerospace Exhibition and the closely followedZhuhai International Movie Festival became Zhuhai’s acceler-ated velocity of advancing towards the world!It is said that starting from now and up to the year of2014,China will import 1320 aeroplanes with an amount of100 billion US dollars.Such a huge market is very seldomhappened in the world.President of Boeing Company,Chair-
文摘happen、occur 和 take place 为同义词,均可表示“发生”。在若干情况下,这三个词可以通过,但它们又各有特点,有些使用上的差异。1.happen:表示事情的发生存在一定的偶然性。What has happened?出什么事了?If anything happens,please let me know.不管发生什么事,都请通知我。How did the car accident happen?车祸是怎么发生的?2.
文摘Reaction products of 2,4,6-tris(4-phenyl-phenoxy)-1,3,5-triazine derived from 4-phenylphenol cyanate ester and phenyl glycidyl ether were analyzed. In addition to an isocyanurate compound and an oxazolidone compound which were well known as reaction products of cyanate esters and epoxy resins, compounds with hybrid ring structure of cyanurate/isocyanurate were determined. Gibbs free energies of the compound having hybrid ring structure of cyanurate/isocyanurate with two isocyanurate moiety were found to be lower than that of the compound with cyanurate ring structure through calculations. Calculation data supported the existence of hybrid ring structure of cy-anurate/isocyanurate. It was revealed that isomerization from cyanurate to isocyanurate occurs via hybrid ring structure of cyanurate/isocyanurate in the reaction of aryl cyanurate and epoxy.