HealthMeasures患者报告结局报告清单的解读

美国匹兹堡大学和HealthMeasures指导委员会及PROMIS健康组织标准委员会共同发表了HealthMeasures患者报告结局报告清单,旨在促进不同患者报告结局测量工具的标准化报告,帮助研究人员提高工具报告质量及结果解释的准确性,进一步改善跨研究间的比较分析。本文对HealthMeasures患者报告结局报告清单的主要内容进行介绍和解读,以期为中国患者报告结局研究者提供参考和借鉴。

人工法off-line HDF对血液透析充分性和高同型半胱氨酸血症的影响

目的探究人工法off-line HDF对维持性血液透析(MHD)患者透析充分性、高同型半胱氨酸血症(HHcy)的影响。方法随机选取2021至2023年于南昌大学第一附属高新医院血液透析中心稳定透析6个月以上的MHD患者30例,进行单中心自身对照研究,时长6个月。前3个月维持每周2次高通量血液透析(HFHD)联合1次on-line HDF,后3个月维持每周2次人工法off-line HDF联合1次on-line HDF。于研究第3个月、第6个月时用全自动生化分析仪检测透析前后血尿素氮(BUN)、血肌酐(SCr)、β2-微球蛋白(β2MG)、同型半胱氨酸(Hcy)、白蛋白(Alb)、C反应蛋白(CRP)、血红蛋白(Hb)、甲状旁腺素(iPTH)、磷(P)、钾(K)水平;计算血清尿素清除指数(Kt/V)、尿素下降率(URR)和β2MG清除率。结果人工法off-line HDF模式透析的Kt/V、URR及β2MG清除率均较显著高于HFHD模式透析(P<0.05);人工法off-lineHDF模式透析Kt/V、URR及β2MG清除率达到透析充分的百分率分别为83.33%、83.33%和93.33%,均显著高于HFHD模式透析(P<0.05)。与HFHD模式透析时相比,人工法off-lineHDF模式透析结束后,患者透析前Hcy水平降低,Alb水平升高(P<0.05)。结论人工法off-line HDF模式透析可显著增加Kt/V、URR和β2MG清除率,提高MHD患者的透析充分性达标率,且对HHcy具有改善作用。

Applying the Shearlet-Based Complexity Measure for Analyzing Mass Transfer in Continuous-Flow Microchannels

Continuous-flow microchannels are widely employed for synthesizing various materials,including nanoparticles,polymers,and metal-organic frameworks(MOFs),to name a few.Microsystem technology allows precise control over reaction parameters,resulting in purer,more uniform,and structurally stable products due to more effective mass transfer manipulation.However,continuous-flow synthesis processes may be accompanied by the emergence of spatial convective structures initiating convective flows.On the one hand,convection can accelerate reactions by intensifying mass transfer.On the other hand,it may lead to non-uniformity in the final product or defects,especially in MOF microcrystal synthesis.The ability to distinguish regions of convective and diffusive mass transfer may be the key to performing higher-quality reactions and obtaining purer products.In this study,we investigate,for the first time,the possibility of using the information complexity measure as a criterion for assessing the intensity of mass transfer in microchannels,considering both spatial and temporal non-uniformities of liquid’s distributions resulting from convection formation.We calculate the complexity using shearlet transform based on a local approach.In contrast to existing methods for calculating complexity,the shearlet transform based approach provides a more detailed representation of local heterogeneities.Our analysis involves experimental images illustrating the mixing process of two non-reactive liquids in a Y-type continuous-flow microchannel under conditions of double-diffusive convection formation.The obtained complexity fields characterize the mixing process and structure formation,revealing variations in mass transfer intensity along the microchannel.We compare the results with cases of liquid mixing via a pure diffusive mechanism.Upon analysis,it was revealed that the complexity measure exhibits sensitivity to variations in the type of mass transfer,establishing its feasibility as an indirect criterion for assessing mass transfer intensity.The method presented can extend beyond flow analysis,finding application in the controlling of microstructures of various materials(porosity,for instance)or surface defects in metals,optical systems and other materials that hold significant relevance in materials science and engineering.

Bunch-length measurement at a bunch-by-bunch rate based on time–frequency-domain joint analysis techniques and its application

This paper presents a new technique for measuring the bunch length of a high-energy electron beam at a bunch-by-bunch rate in storage rings.This technique uses the time–frequency-domain joint analysis of the bunch signal to obtain bunch-by-bunch and turn-by-turn longitudinal parameters,such as bunch length and synchronous phase.The bunch signal is obtained using a button electrode with a bandwidth of several gigahertz.The data acquisition device was a high-speed digital oscilloscope with a sampling rate of more than 10 GS/s,and the single-shot sampling data buffer covered thousands of turns.The bunch-length and synchronous phase information were extracted via offline calculations using Python scripts.The calibration coefficient of the system was determined using a commercial streak camera.Moreover,this technique was tested on two different storage rings and successfully captured various longitudinal transient processes during the harmonic cavity debugging process at the Shanghai Synchrotron Radiation Facility(SSRF),and longitudinal instabilities were observed during the single-bunch accumulation process at Hefei Light Source(HLS).For Gaussian-distribution bunches,the uncertainty of the bunch phase obtained using this technique was better than 0.2 ps,and the bunch-length uncertainty was better than 1 ps.The dynamic range exceeded 10 ms.This technology is a powerful and versatile beam diagnostic tool that can be conveniently deployed in high-energy electron storage rings.

A New Device for Gas-Liquid Flow Measurements Relying on Forced Annular Flow

A new measurement device,consisting of swirling blades and capsule-shaped throttling elements,is proposed in this study to eliminate typical measurement errors caused by complex flow patterns in gas-liquid flow.The swirling blades are used to transform the complex flow pattern into a forced annular flow.Drawing on the research of existing blockage flow meters and also exploiting the single-phase flow measurement theory,a formula is introduced to measure the phase-separated flow of gas and liquid.The formula requires the pressure ratio,Lockhart-Martinelli number(L-M number),and the gas phase Froude number.The unknown parameters appearing in the formula are fitted through numerical simulation using computational fluid dynamics(CFD),which involves a comprehensive analysis of the flow field inside the device from multiple perspectives,and takes into account the influence of pressure fluctuations.Finally,the measurement model is validated through an experimental error analysis.The results demonstrate that the measurement error can be maintained within±8%for various flow patterns,including stratified flow,bubble flow,and wave flow.

Enhancing Energy Efficiency with a Dynamic Trust Measurement Scheme in Power Distribution Network

The application of Intelligent Internet of Things(IIoT)in constructing distribution station areas strongly supports platform transformation,upgrade,and intelligent integration.The sensing layer of IIoT comprises the edge convergence layer and the end sensing layer,with the former using intelligent fusion terminals for real-time data collection and processing.However,the influx of multiple low-voltage in the smart grid raises higher demands for the performance,energy efficiency,and response speed of the substation fusion terminals.Simultaneously,it brings significant security risks to the entire distribution substation,posing a major challenge to the smart grid.In response to these challenges,a proposed dynamic and energy-efficient trust measurement scheme for smart grids aims to address these issues.The scheme begins by establishing a hierarchical trust measurement model,elucidating the trust relationships among smart IoT terminals.It then incorporates multidimensional measurement factors,encompassing static environmental factors,dynamic behaviors,and energy states.This comprehensive approach reduces the impact of subjective factors on trust measurements.Additionally,the scheme incorporates a detection process designed for identifying malicious low-voltage end sensing units,ensuring the prompt identification and elimination of any malicious terminals.This,in turn,enhances the security and reliability of the smart grid environment.The effectiveness of the proposed scheme in pinpointing malicious nodes has been demonstrated through simulation experiments.Notably,the scheme outperforms established trust metric models in terms of energy efficiency,showcasing its significant contribution to the field.

Measuring small longitudinal phase shifts via weak measurement amplification

Weak measurement amplification,which is considered as a very promising scheme in precision measurement,has been applied to various small physical quantities estimations.Since many physical quantities can be converted into phase signals,it is interesting and important to consider measuring small longitudinal phase shifts by using weak measurement.Here,we propose and experimentally demonstrate a novel weak measurement amplification-based small longitudinal phase estimation,which is suitable for polarization interferometry.We realize one order of magnitude amplification measurement of a small phase signal directly introduced by a liquid crystal variable retarder and show that it is robust to the imperfection of interference.Besides,we analyze the effect of magnification error which is never considered in the previous works,and find the constraint on the magnification.Our results may find important applications in high-precision measurements,e.g.,gravitational wave detection.

Research progress on micro-force measurement of a hydrate particle system

It remains a great challenge to understand the hydrates involved in phenomena in practical oil and gas systems.The adhesion forces between hydrate particles,between hydrate particles and pipe walls,and between hydrate particles and reservoir particles are essential factors that control the behaviors of clathrate hydrates in different applications.In this review,we summarize the typical micro-force measurement apparatus and methods utilized to study hydrate particle systems.In addition,the adhesion test results,the related understandings,and the applied numerical calculation models are systematically discussed.

Improved spatio-temporal alignment measurement method for hull deformation

In this paper,an improved spatio-temporal alignment measurement method is presented to address the inertial matching measurement of hull deformation under the coexistence of time delay and large misalignment angle.Large misalignment angle and time delay often occur simultaneously and bring great challenges to the accurate measurement of hull deformation in space and time.The proposed method utilizes coarse alignment with large misalignment angle and time delay estimation of inertial measurement unit modeling to establish a brand-new spatiotemporal aligned hull deformation measurement model.In addition,two-step loop control is designed to ensure the accurate description of dynamic deformation angle and static deformation angle by the time-space alignment method of hull deformation.The experiments illustrate that the proposed method can effectively measure the hull deformation angle when time delay and large misalignment angle coexist.

Unknown Environment Measurement Mapping by Unmanned Aerial Vehicle Using Kalman Filter-Based Low-Cost Estimated Parallel 8-Beam LIDAR

The measurement and mapping of objects in the outer environment have traditionally been conducted using ground-based monitoring systems,as well as satellites.More recently,unmanned aerial vehicles have also been employed for this purpose.The accurate detection and mapping of a target such as buildings,trees,and terrains are of utmost importance in various applications of unmanned aerial vehicles(UAVs),including search and rescue operations,object transportation,object detection,inspection tasks,and mapping activities.However,the rapid measurement and mapping of the object are not currently achievable due to factors such as the object’s size,the intricate nature of the sites,and the complexity of mapping algorithms.The present system introduces a costeffective solution for measurement and mapping by utilizing a small unmanned aerial vehicle(UAV)equipped with an 8-beam Light Detection and Ranging(LiDAR)system.This approach offers advantages over traditional methods that rely on expensive cameras and complex algorithm-based approaches.The reflective properties of laser beams have also been investigated.The system provides prompt results in comparison to traditional camerabased surveillance,with minimal latency and the need for complex algorithms.The Kalman estimation method demonstrates improved performance in the presence of noise.The measurement and mapping of external objects have been successfully conducted at varying distances,utilizing different resolutions.

Measurement and Analysis of Vibration Effect of Free-falling Corner Cube Driving Mechanism in Free Fall Absolute Gravimeter

The vibration interference of the reference corner cube runs through the free flight process of the free-falling corner cube,which is superimposed on the whole laser interference fringes.Thus,it is necessary to solve the interference fringes with the entire fringe to analyze the quantitative influence of vibration on gravity measurements.

A new centrality measure based on neighbor loop structure for network dismantling

Nearly all real-world networks are complex networks and usually are in danger of collapse.Therefore,it is crucial to exploit and understand the mechanisms of network attacks and provide better protection for network functionalities.Network dismantling aims to find the smallest set of nodes such that after their removal the network is broken into connected components of sub-extensive size.To overcome the limitations and drawbacks of existing network dismantling methods,this paper focuses on network dismantling problem and proposes a neighbor-loop structure based centrality metric,NL,which achieves a balance between computational efficiency and evaluation accuracy.In addition,we design a novel method combining NL-based nodes-removing,greedy tree-breaking and reinsertion.Moreover,we compare five baseline methods with our algorithm on ten widely used real-world networks and three types of model networks including Erd€os-Renyi random networks,Watts-Strogatz smallworld networks and Barabasi-Albert scale-free networks with different network generation parameters.Experimental results demonstrate that our proposed method outperforms most peer methods by obtaining a minimal set of targeted attack nodes.Furthermore,the insights gained from this study may be of assistance to future practical research into real-world networks.

Design and application of thickness measurement calibration system based on laser displacement sensor

This study aims to improve the accuracy and safety of steel plate thickness calibration.A differential noncontact thickness measurement calibration system based on laser displacement sensors was designed to address the problems of low precision of traditional contact thickness gauges and radiation risks of radiation-based thickness gauges.First,the measurement method and measurement structure of the thickness calibration system were introduced.Then,the hardware circuit of the thickness system was established based on the STM32 core chip.Finally,the system software was designed to implement system control to filter algorithms and human-computer interaction.Experiments have proven the excellent performance of the differential noncontact thickness measurement calibration system based on laser displacement sensors,which not only considerably improves measurement accuracy but also effectively reduces safety risks during the measurement process.The system offers guiding significance and application value in the field of steel plate production and processing.

A fast forward computational method for nuclear measurement using volumetric detection constraints

Owing to the complex lithology of unconventional reservoirs,field interpreters usually need to provide a basis for interpretation using logging simulation models.Among the various detection tools that use nuclear sources,the detector response can reflect various types of information of the medium.The Monte Carlo method is one of the primary methods used to obtain nuclear detection responses in complex environments.However,this requires a computational process with extensive random sampling,consumes considerable resources,and does not provide real-time response results.Therefore,a novel fast forward computational method(FFCM)for nuclear measurement that uses volumetric detection constraints to rapidly calculate the detector response in various complex environments is proposed.First,the data library required for the FFCM is built by collecting the detection volume,detector counts,and flux sensitivity functions through a Monte Carlo simulation.Then,based on perturbation theory and the Rytov approximation,a model for the detector response is derived using the flux sensitivity function method and a one-group diffusion model.The environmental perturbation is constrained to optimize the model according to the tool structure and the impact of the formation and borehole within the effective detection volume.Finally,the method is applied to a neutron porosity tool for verification.In various complex simulation environments,the maximum relative error between the calculated porosity results of Monte Carlo and FFCM was 6.80%,with a rootmean-square error of 0.62 p.u.In field well applications,the formation porosity model obtained using FFCM was in good agreement with the model obtained by interpreters,which demonstrates the validity and accuracy of the proposed method.

Microstructural and thermal properties of coal measure sandstone subjected to high temperatures

To study the microscopic structure,thermal and mechanical properties of sandstones under the influence of temperature,coal measure sandstones from Southwest China are adopted as the research object to carry out high-temperature tests at 25℃-1000℃.The microscopic images of sandstone after thermal treatment are obtained by means of polarizing microscopy and scanning electron microscopy(SEM).Based on thermogravimetric(TG)analysis and differential scanning calorimetric(DSC)analysis,the model function of coal measure sandstone is explored through thermal analysis kinetics(TAK)theory,and the kinetic parameters of thermal decomposition and the thermal decomposition reaction rate of rock are studied.Through the uniaxial compression experiments,the stress‒strain curves and strength characteristics of sandstone under the influence of temperature are obtained.The results show that the temperature has a significant effect on the microstructure,mineral composition and mechanical properties of sandstone.In particular,when the temperature exceeds 400℃,the thermal fracture phenomenon of rock is obvious,the activity of activated molecules is significantly enhanced,and the kinetic phenomenon of the thermal decomposition reaction of rock appears rapidly.The mechanical properties of rock are weakened under the influence of rock thermal fracture and mineral thermal decomposition.These research results can provide a reference for the analysis of surrounding rock stability and the control of disasters caused by thermal damage in areas such as underground coal gasification(UCG)channels and rock masses subjected to mine fires.

A seismic elastic moduli module for the measurements of low-frequency wave dispersion and attenuation of fluid-saturated rocks under different pressures

Knowledge about the seismic elastic modulus dispersion,and associated attenuation,in fluid-saturated rocks is essential for better interpretation of seismic observations taken as part of hydrocarbon identification and time-lapse seismic surveillance of both conventional and unconventional reservoir and overburden performances.A Seismic Elastic Moduli Module has been developed,based on the forced-oscillations method,to experimentally investigate the frequency dependence of Young's modulus and Poisson's ratio,as well as the inferred attenuation,of cylindrical samples under different confining pressure conditions.Calibration with three standard samples showed that the measured elastic moduli were consistent with the published data,indicating that the new apparatus can operate reliably over a wide frequency range of f∈[1-2000,10^(6)]Hz.The Young's modulus and Poisson's ratio of the shale and the tight sandstone samples were measured under axial stress oscillations to assess the frequency-and pressure-dependent effects.Under dry condition,both samples appear to be nearly frequency independent,with weak pressure dependence for the shale and significant pressure dependence for the sandstone.In particular,it was found that the tight sandstone with complex pore microstructure exhibited apparent dispersion and attenuation under brine or glycerin saturation conditions,the levels of which were strongly influenced by the increased effective pressure.In addition,the measured Young's moduli results were compared with the theoretical predictions from a scaled poroelastic model with a reasonably good agreement,revealing that the combined fluid flow mechanisms at both mesoscopic and microscopic scales possibly responsible for the measured dispersion.

Quantum block coherence with respect to projective measurements

Quantum coherence serves as a defining characteristic of quantum mechanics,finding extensive applications in quantum computing and quantum communication processing.This study explores quantum block coherence in the context of projective measurements,focusing on the quantification of such coherence.Firstly,we define the correlation function between the two general projective measurements P and Q,and analyze the connection between sets of block incoherent states related to two compatible projective measurements P and Q.Secondly,we discuss the measure of quantum block coherence with respect to projective measurements.Based on a given measure of quantum block coherence,we characterize the existence of maximal block coherent states through projective measurements.This research integrates the compatibility of projective measurements with the framework of quantum block coherence,contributing to the advancement of block coherence measurement theory.

Deterioration Reason and Improvement Measure of the Retarding Effect of Protein Retarder on Phosphorus Building Gypsum

The retarding effect of protein retarder on phosphorus building gypsum(PBG)and desulfurization building gypsum(DBG)was investigated,and the results show that protein retarder for DBG can effectively prolong the setting time and displays a better retarding effect,but for PBG shows a poor retarding effect.Furthermore,the deterioration reason of the retarding effect of protein retarder on PBG was investigated by measuring the pH value and the retarder concentration of the liquid phase from vacuum filtration of PBG slurry at different hydration time,and the measure to improve the retarding effect of protein retarding on PBG was suggested.The pH value of PBG slurry(<5.0)is lower than that of DBG slurry(7.8-8.5).After hydration for 5 min,the concentration of retarder in liquid phase of DBG slurry gradually decreases,but in liquid phase of PBG slurry continually increases,which results in the worse retarding effect of protein retarder on PBG.The liquid phase pH value of PBG slurry can be adjusted higher by sodium silicate,which is beneficial to improvement in the retarding effect of the retarder.By adding 1.0%of sodium silicate,the initial setting time of PBG was efficiently prolonged from 17 to 210 min,but little effect on the absolute dry flexural strength was observed.

Fast compressed sensing spectral measurement with adaptive gradient multiscale resolution

We propose a fast,adaptive multiscale resolution spectral measurement method based on compressed sensing.The method can apply variable measurement resolution over the entire spectral range to reduce the measurement time by over 75%compared to a global high-resolution measurement.Mimicking the characteristics of the human retina system,the resolution distribution follows the principle of gradually decreasing.The system allows the spectral peaks of interest to be captured dynamically or to be specified a priori by a user.The system was tested by measuring single and dual spectral peaks,and the results of spectral peaks are consistent with those of global high-resolution measurements.

Finesse measurement for high-power optical enhancement cavity

Finesse is a critical parameter for describing the characteristics of an optical enhancement cavity(OEC). This paper first presents a review of finesse measurement techniques, including a comparative analysis of the advantages, disadvantages, and potential limitations of several main methods from both theoretical and practical perspectives. A variant of the existing method called the free spectral range(FSR) modulation method is proposed and compared with three other finesse measurement methods, i.e., the fast-switching cavity ring-down(CRD) method, the rapidly swept-frequency(SF) CRD method, and the ringing effect method. A high-power OEC platform with a high finesse of approximately 16000 is built and measured with the four methods. The performance of these methods is compared, and the results show that the FSR modulation method and the fast-switching CRD method are more suitable and accurate than the other two methods for high-finesse OEC measurements. The CRD method and the ringing effect method can be implemented in open loop using simple equipment and are easy to perform. Additionally, recommendations for selecting finesse measurement methods under different conditions are proposed, which benefit the development of OEC and its applications.