Impact of time between meniscal injury and isolated meniscus repair on post-operative outcomes:A systematic review

BACKGROUND Meniscal tears are one of the most common knee injuries.After the diagnosis of a meniscal tear has been made,there are several factors physicians use to guide clinical decision-making.The influence of time between injury and isolated meniscus repair on patient outcomes is not well described.Assessing this relationship is important as it may influence clinical decision-making and can add to the preoperative patient education process.We hypothesized that increasing the time from injury to meniscus surgery would worsen postoperative outcomes.AIM To investigate the current literature for data on the relationship between time between meniscus injury and repair on patient outcomes.METHODS PubMed,Academic Search Complete,MEDLINE,CINAHL,and SPORTDiscus were searched for studies published between January 1,1995 and July 13,2023 on isolated meniscus repair.Exclusion criteria included concomitant ligament surgery,incomplete outcomes or time to surgery data,and meniscectomies.Patient demographics,time to injury,and postoperative outcomes from each study were abstracted and analyzed.RESULTS Five studies met all inclusion and exclusion criteria.There were 204(121 male,83 female)patients included.Three of five(60%)studies determined that time between injury and surgery was not statistically significant for postoperative Lysholm scores(P=0.62),Tegner scores(P=0.46),failure rate(P=0.45,P=0.86),and International Knee Documentation Committee scores(P=0.65).Two of five(40%)studies found a statistically significant increase in Lysholm scores with shorter time to surgery(P=0.03)and a statistically significant association between progression of medial meniscus extrusion ratio(P=0.01)and increasing time to surgery.CONCLUSION Our results do not support the hypothesis that increased time from injury to isolated meniscus surgery worsens postoperative outcomes.Decision-making primarily based on injury interval is thus not recommended.

Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°C.We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort.Plasma samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline project.These samples were stored at-80°C for up to 6 years before being used in this study.Our results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage time.However,the level of total tau showed a negative correlation with sample storage time.Notably,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage time.This was not observed in individuals with cognitive impairment.Consequently,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time.Therefore,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's disease.Furthermore,in cohort studies,it is important to consider the impact of storage time on the overall results.

4种植物源性成分多重real-time PCR检测方法的建立及其在食用淀粉中的应用

建立一种可同时快速检测红薯、木薯、马铃薯、玉米源性成分的多重实时聚合酶链式反应(real-time polymerase chain reaction,real-time PCR)方法。分别以红薯g3pdh基因、木薯g3pdh基因、马铃薯UGPase基因、玉米zSSIIb基因为靶基因设计特异性引物和TaqMan探针,以18S rRNA基因为内参基因,建立多重real-time PCR方法,开展方法学验证,并对不同掺入比例模拟样品和实际淀粉样品进行检测。结果显示,该方法具有高通量、特异性强、灵敏度高等优点。与15种非目标源性均无交叉反应;对目标DNA的检测灵敏度可达到3×10^(-3) ng/μL,且具有良好的线性关系和扩增效率;对淀粉样品的检出限可达0.1%,对50份实际样品进行检测,结果与参比方法一致,说明建立的多重real-time PCR法可用于食用淀粉种类掺假鉴别检测。

TIME-HARMONIC DYNAMIC GREEN'S FUNCTIONS FOR ONE-DIMENSIONAL HEXAGONAL QUASICRYSTALS

Quasicrystals have additional phason degrees of freedom not found in conventional crystals. In this paper, we present an exact solution for time-harmonic dynamic Green＇s function of one-dimensional hexagonal quasicrystals with the Laue classes 6/mh and 6/mhmm. Through the introduction of two new functions φ and ψ, the original problem is reduced to the determination of Green＇s functions for two independent Helmholtz equations. The explicit expressions of displacement and stress fields are presented and their asymptotic behaviors are discussed. The static Green＇s function can be obtained by letting the circular frequency approach zero.

ICON/MIGHTI与TIMED/SABER探测温度数据的对比

ICON卫星为临近空间环境特性研究、建模和预报提供了新数据.通过对ICON/MIGHTI与TIMED/SABER在90~105 km高度探测温度数据的比较,计算两者的年平均温度偏差和均方根误差,同时分析月平均温度偏差在不同月份中随高度和纬度的分布情况,为MIGHTI和SABER温度探测数据在临近空间大气建模和预报应用提供参考依据.结果表明,MIGHTI和SABER的温度垂直廓线变化趋势基本吻合,数值上有所差异.在12°S-42°N范围内,MIGHTI探测温度与SABER相比,在90~93 km时偏低,偏差最大值约2.5 K,在93~105 km偏高,偏差的绝对值最大约10 K.在不同季节,白天的温度偏差通常高于夜晚.SABER和MIGHTI的月平均温度偏差随季节和纬度的变化显著,夏季时的月平均温度偏差最大,且温度的均方根误差最大.

Partition-Time Masking:一种唇语识别数据增强方法

提出了一种唇语识别数据增强方法Partition-Time Masking。该方法直接作用于输入数据,通过将输入划分为多个子序列再分别进行Mask操作最后再将各子序列按序拼接,使得模型能对部分帧缺失的输入具有更强的鲁棒性,从而增强泛化能力。实验前根据划分的子序列数目与掩码值来源不同而设计了5种增强策略,并与唇语识别研究中最重要的数据增强方法Time Masking进行了对比实验。实验在LRW数据集和LRW1000数据集上进行,实验结果表明Partition-Time Masking方法对模型性能提升的效果要优于Time Masking方法,其中子序列数目为3、掩码值选择各子序列平均帧时为最优策略,该策略使得目前最佳的唇语识别模型DC-TCN的性能从89.6%提高到90.0%。

The space time CE/SE method for solving one-dimensional batch crystallization model with fines dissolution

This article is concerned with the numerical investigation of one-dimensional population balance models for batch crystallization process with fines dissolution.In batch crystallization,dissolution of smaller unwanted nuclei below some critical size is of vital importance as it improves the quality of product.The crystal growth rates for both size-independent and size-dependent cases are considered.A delay in recycle pipe is also included in the model.The space–time conservation element and solution element method,originally derived for non-reacting flows,is used to solve the model.This scheme has already been applied to a range of PDEs,mainly in the area of fluid mechanics.The numerical results are compared with those obtained from the Koren scheme,showing that the proposed scheme is more efficient.

TimeGAN-Informer长时机场能见度预测

能见度的预测对机场的业务决策、保障飞机的安全起降具有重要的意义。针对现有能见度预测模型预测时间较短的问题,提出一种基于TimeGAN Informer(Time Generative Adversarial Network-Informer)的机场能见度预测方法。利用2018—2022年气象和污染物数据,通过相关系数法和递归特征消除法提取出能见度的主要影响因素,使用TimeGAN时间序列生成对抗网络对数据进行扩充,并将Informer长时间序列预测模型应用于能见度预测。结果显示:当预测步长为1 d、2 d、3 d时,TimeGAN Informer的绝对误差(Mean Absolute Error,MAE)分别为2.42、3.13、3.57,比Informer分别降低了0.29、0.27、0.28,比长短时记忆网络(Long Short-Term Memory,LSTM)分别降低了0.28、0.49、0.63;均方根误差(Root Mean Square Error,RMSE)分别为3.03、3.7、4.09,比Informer分别降低了0.38、0.22、0.24,比长短时记忆网络(LSTM)分别降低了0.3、0.5、1.04;百分误差小于30%的分别占测试样本集的78.07%、70.68%、63.84%。尽管随着步长的增加预测效果变差,但在预测步长为3 d时,多数样本的预测误差仍小于30%,实现了对机场区域较为准确的长时能见度预测。

Localization and Steering of Light in One-Dimensional Parity-Time Symmetric Photonic Lattices

We theoretically study the propagation dynamics of input light in one-dimensional mixed linear-nonlinear photonic lattices with a complex parity-time symmetric potential. Numerical computation shows simultaneous localization and steering of the optical beam due to the asymmetric scatter and interplay between Kerr-type nonlinearity and PT symmetry. This may provide a feasible measure for manipulation light in optical communications, integrated optics and so on.

ONE-DIMENSIONAL CONSOLIDATION OF LAYERED SOILS WITH IMPEDED BOUNDARIES UNDER TIME-DEPENDENT LOADINGS

On the basis of Terzaghi's one-dimensional consolidation theory, the variation of effective stress ratio in layered saturated soils with impeded boundaries under time-dependent loading was studied. By the method of Laplace transform, the solution was presented. Influences of different kinds of cyclic loadings and impeded boundaries conditions were discussed. Through numerical inversion of Laplace transform, useful illustrations were given considering several common time-dependent loadings. Pervious or impervious boundary condition is just the special case of the problem considered here. Compared with average index method,the results from the method illustrated are more accurate.

An efficient locally one-dimensional finite-difference time-domain method based on the conformal scheme

An efficient conformal locally one-dimensional finite-difference time-domain（LOD-CFDTD） method is presented for solving two-dimensional（2D） electromagnetic（EM） scattering problems. The formulation for the 2D transverse-electric（TE） case is presented and its stability property and numerical dispersion relationship are theoretically investigated. It is shown that the introduction of irregular grids will not damage the numerical stability. Instead of the staircasing approximation, the conformal scheme is only employed to model the curve boundaries, whereas the standard Yee grids are used for the remaining regions. As the irregular grids account for a very small percentage of the total space grids, the conformal scheme has little effect on the numerical dispersion. Moreover, the proposed method, which requires fewer arithmetic operations than the alternating-direction-implicit（ADI） CFDTD method, leads to a further reduction of the CPU time. With the total-field/scattered-field（TF/SF） boundary and the perfectly matched layer（PML）, the radar cross section（RCS） of two2 D structures is calculated. The numerical examples verify the accuracy and efficiency of the proposed method.

基于TimeGAN数据增强的复杂过程故障分类方法

针对传统基于重构的故障分类方法在故障样本稀疏或失衡情况下效果不佳、故障子空间区分能力弱的问题,提出基于TimeGAN数据增强的复杂过程故障分类方法.针对小子样故障,使用TimeGAN对历史故障数据进行数据增强,生成与历史数据分布相似的虚拟故障样本;采用马氏距离评估虚拟样本的质量,剔除不可信样本,构造平衡的故障样本集.将故障样本映射到高维核空间,并在核空间中提取故障子空间.设计故障分类策略并定义4种故障分类性能评估指标以定量衡量算法的分类性能.Tennessee Eastman应用结果表明,所提数据增强方法可以有效扩充故障样本,进而提高故障重构率.与WGAN-GP和SMOTE方法进行对比,发现基于TimeGAN数据增强的故障分类方法具有更好的分类性能.

Determination of Kolmogorov Entropy of Chaotic Attractor Included in One-Dimensional Time Series of Meteorological Data

The 1970-1985 day to day averaged pressure dataset of Shanghai and the extension method in phase space are used to calculate the correlation dimension D and the second-order Renyi entropy K2 of the approximation of Kolmogorov's entropy, the fractional dimension D = 7.7-7.9 and the positive value K2 - 0.1 are obtained. This shows that the attractor for the short-term weather evolution in the monsoon region of China exhibits a chaotic motion. The estimate of K2 yields a predictable time scale of about ten days. This result is in agreement with that obtained earlier by the dynamic-statistical approach.The effects of the lag time i on the estimate of D and K2 are investigated. The results show that D and K2 are convergent with respect to i. The day to day averaged pressure series used in this paper are treated for the extensive phase space with T = 5, the coordinate components are independent of each other; therefore, the dynamical character quantities of the system are stable and reliable.

Brain Time Stack图像融合技术在CT中的应用

目的:分析Brain Time Stack图像融合技术在CT中的应用。方法:选取2021年3月—2022年9月衡水市第四人民医院收治的50例CT检查患者作为研究对象。所有患者进行CT检查并进行Brain Time Stack后处理。比较四组不同部位CT值、标准差(SD)、信噪比(SNR)。比较四组图像主观质量评分。分析不同部位CT值、SD、SNR与图像主观质量评分的相关性。结果:B组的延髓、额叶灰质、额叶白质、小脑内侧、小脑外侧、颞肌肌肉CT值明显低于A组;C组的延髓、脑室、额叶白质、小脑内侧、小脑外侧、颞肌肌肉CT值高于A组;D组延髓、额叶灰质、颞肌肌肉CT值明显低于A组,脑室、额叶白质、小脑外侧CT值明显高于A组;C组延髓、额叶灰质、额叶白质、小脑内侧、小脑外侧、颞肌肌肉CT值明显高于B组;D组延髓、脑室、额叶白质、小脑内侧、小脑外侧、颞肌肌肉CT值明显高于B组;D组延髓、额叶灰质、额叶白质、小脑内侧、小脑外侧、颞肌肌肉CT值明显低于C组;D组脑室CT值明显高于C组,差异有统计学意义(P<0.05)。B组、C组、D组延髓、脑室、额叶灰质、额叶白质、小脑内侧、小脑外侧、颞肌肌肉SD值明显低于A组;C组延髓、脑室、额叶白质、小脑内侧、小脑外侧、颞肌肌肉SD值均明显高于B组;C组额叶灰质SD明显低于B组;D组延髓、脑室、额叶灰质、额叶白质、小脑内侧、小脑外侧、肌肉SD均明显低于B组、C组,差异有统计学意义(P<0.05)。B组、C组、D组延髓、脑室、额叶灰质、额叶白质、小脑内侧、小脑外侧、颞肌肌肉SNR均明显高于A组;C组、D组延髓、额叶灰质、额叶白质、小脑内侧、小脑外侧、颞肌肌肉SNR值明显高于B组;C组、D组脑室SNR明显低于B组;D组延髓、脑室、额叶灰质、额叶白质、小脑内侧、小脑外侧、颞肌肌肉SNR明显高于C组,差异有统计学意义(P<0.05)。D组图像主观质量评分最高,差异有统计学意义(P<0.05)。延髓、脑室、额叶灰质、额叶白质、小脑内侧、小脑外侧及颞肌肌肉SD与主观质量评分呈明显负相关,SNR与主观质量评分间呈明显正相关,差异有统计学意义(P<0.05)。结论:利用Brain Time Stack图像融合技术对头部CT扫描检查图像处理,动脉期结合前一期及后一期的图像数据在处理后具有更好的质量和更少的噪音。

Association of daily sitting time and leisure-time physical activity with body fat among U.S.adults

Background:Prolonged sitting and reduced physical activity lead to low energy expenditures.However,little is known about the joint impact of daily sitting time and physical activity on body fat distribution.We investigated the independent and joint associations of daily sitting time and physical activity with body fat among adults.Methods:This was a cross-sectional analysis of U.S.nationally representative data from the National Health and Nutrition Examination Survey2011-2018 among adults aged 20 years or older.Daily sitting time and leisure-time physical activity(LTPA)were self-reported using the Global Physical Activity Questionnaire.Body fat(total and trunk fat percentage)was determined via dual X-ray absorptiometry.Results:Among 10,808 adults,about 54.6%spent 6 h/day or more sitting;more than one-half reported no LTPA(inactive)or less than 150 min/week LTPA(insufficiently active)with only 43.3%reported 150 min/week or more LTPA(active)in the past week.After fully adjusting for sociodemographic data,lifestyle behaviors,and chronic conditions,prolonged sitting time and low levels of LTPA were associated with higher total and trunk fat percentages in both sexes.When stratifying by LTPA,the association between daily sitting time and body fat appeared to be stronger in those who were inactive/insuufficiently active.In the joint analyses,inactive/insuufficiently active adults who reported sitting more than 8 h/day had the highest total(female:3.99%(95%confidence interval(95%CI):3.09%-4.88%);male:3.79%(95%CI:2.75%-4.82%))and trunk body fat percentages(female:4.21%(95%CI:3.09%-5.32%);male:4.07%(95%CI:2.95%-5.19%))when compared with those who were active and sitting less than 4 h/day.Conclusion:Prolonged daily sitting time was associated with increased body fat among U.S.adults.The higher body fat associated with 6 h/day sitting may not be offset by achieving recommended levels of physical activity.

Hybrid model for BOF oxygen blowing time prediction based on oxygen balance mechanism and deep neural network

The amount of oxygen blown into the converter is one of the key parameters for the control of the converter blowing process,which directly affects the tap-to-tap time of converter. In this study, a hybrid model based on oxygen balance mechanism (OBM) and deep neural network (DNN) was established for predicting oxygen blowing time in converter. A three-step method was utilized in the hybrid model. First, the oxygen consumption volume was predicted by the OBM model and DNN model, respectively. Second, a more accurate oxygen consumption volume was obtained by integrating the OBM model and DNN model. Finally, the converter oxygen blowing time was calculated according to the oxygen consumption volume and the oxygen supply intensity of each heat. The proposed hybrid model was verified using the actual data collected from an integrated steel plant in China, and compared with multiple linear regression model, OBM model, and neural network model including extreme learning machine, back propagation neural network, and DNN. The test results indicate that the hybrid model with a network structure of 3 hidden layer layers, 32-16-8 neurons per hidden layer, and 0.1 learning rate has the best prediction accuracy and stronger generalization ability compared with other models. The predicted hit ratio of oxygen consumption volume within the error±300 m^(3)is 96.67%;determination coefficient (R^(2)) and root mean square error (RMSE) are0.6984 and 150.03 m^(3), respectively. The oxygen blow time prediction hit ratio within the error±0.6 min is 89.50%;R2and RMSE are0.9486 and 0.3592 min, respectively. As a result, the proposed model can effectively predict the oxygen consumption volume and oxygen blowing time in the converter.

Time series prediction of reservoir bank landslide failure probability considering the spatial variability of soil properties

Historically,landslides have been the primary type of geological disaster worldwide.Generally,the stability of reservoir banks is primarily affected by rainfall and reservoir water level fluctuations.Moreover,the stability of reservoir banks changes with the long-term dynamics of external disastercausing factors.Thus,assessing the time-varying reliability of reservoir landslides remains a challenge.In this paper,a machine learning(ML)based approach is proposed to analyze the long-term reliability of reservoir bank landslides in spatially variable soils through time series prediction.This study systematically investigated the prediction performances of three ML algorithms,i.e.multilayer perceptron(MLP),convolutional neural network(CNN),and long short-term memory(LSTM).Additionally,the effects of the data quantity and data ratio on the predictive power of deep learning models are considered.The results show that all three ML models can accurately depict the changes in the time-varying failure probability of reservoir landslides.The CNN model outperforms both the MLP and LSTM models in predicting the failure probability.Furthermore,selecting the right data ratio can improve the prediction accuracy of the failure probability obtained by ML models.

Prescribed Performance Tracking Control of Time-Delay Nonlinear Systems With Output Constraints

The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requirements, i.e., boundedness and the local Lipschitz condition, are assumed for the allowable time delays. Moreover, we focus on the case where the reference is unknown beforehand, which renders the standard prescribed performance control designs under output constraints infeasible. To conquer these challenges, a novel robust prescribed performance control approach is put forward in this paper.Herein, a reverse tuning function is skillfully constructed and automatically generates a performance envelop for the tracking error. In addition, a unified performance analysis framework based on proof by contradiction and the barrier function is established to reveal the inherent robustness of the control system against the time delays. It turns out that the system output tracks the reference with a preassigned settling time and good accuracy,without constraint violations. A comparative simulation on a two-stage chemical reactor is carried out to illustrate the above theoretical findings.

Defect Detection Model Using Time Series Data Augmentation and Transformation

Time-series data provide important information in many fields,and their processing and analysis have been the focus of much research.However,detecting anomalies is very difficult due to data imbalance,temporal dependence,and noise.Therefore,methodologies for data augmentation and conversion of time series data into images for analysis have been studied.This paper proposes a fault detection model that uses time series data augmentation and transformation to address the problems of data imbalance,temporal dependence,and robustness to noise.The method of data augmentation is set as the addition of noise.It involves adding Gaussian noise,with the noise level set to 0.002,to maximize the generalization performance of the model.In addition,we use the Markov Transition Field(MTF)method to effectively visualize the dynamic transitions of the data while converting the time series data into images.It enables the identification of patterns in time series data and assists in capturing the sequential dependencies of the data.For anomaly detection,the PatchCore model is applied to show excellent performance,and the detected anomaly areas are represented as heat maps.It allows for the detection of anomalies,and by applying an anomaly map to the original image,it is possible to capture the areas where anomalies occur.The performance evaluation shows that both F1-score and Accuracy are high when time series data is converted to images.Additionally,when processed as images rather than as time series data,there was a significant reduction in both the size of the data and the training time.The proposed method can provide an important springboard for research in the field of anomaly detection using time series data.Besides,it helps solve problems such as analyzing complex patterns in data lightweight.

Real-time Rescue Target Detection Based on UAV Imagery for Flood Emergency Response

Timely acquisition of rescue target information is critical for emergency response after a flood disaster.Unmanned Aerial Vehicles(UAVs)equipped with remote sensing capabilities offer distinct advantages,including high-resolution imagery and exceptional mobility,making them well suited for monitoring flood extent and identifying rescue targets during floods.However,there are some challenges in interpreting rescue information in real time from flood images captured by UAVs,such as the complexity of the scenarios of UAV images,the lack of flood rescue target detection datasets and the limited real-time processing capabilities of the airborne on-board platform.Thus,we propose a real-time rescue target detection method for UAVs that is capable of efficiently delineating flood extent and identifying rescue targets(i.e.,pedestrians and vehicles trapped by floods).The proposed method achieves real-time rescue information extraction for UAV platforms by lightweight processing and fusion of flood extent extraction model and target detection model.The flood inundation range is extracted by the proposed method in real time and detects targets such as people and vehicles to be rescued based on this layer.Our experimental results demonstrate that the Intersection over Union(IoU)for flood water extraction reaches an impressive 80%,and the IoU for real-time flood water extraction stands at a commendable 76.4%.The information on flood stricken targets extracted by this method in real time can be used for flood emergency rescue.