AIM: To study the natural progression of diabetic retinopathy in patients with type 2 diabetes.METHODS: This was an observational study of 153 cases with type 2 diabetes from 2010 to 2013. The state of patient was not...AIM: To study the natural progression of diabetic retinopathy in patients with type 2 diabetes.METHODS: This was an observational study of 153 cases with type 2 diabetes from 2010 to 2013. The state of patient was noted at end of each year and transition matrices were developed to model movement between years. Patients who progressed to severe non-proliferative diabetic retinopathy(NPDR) were treated.Markov Chains and Chi-square test were used for statistical analysis.RESULTS: We modelled the transition of 153 patients from NPDR to blindness on an annual basis. At the end of year 3, we compared results from the Markov model versus actual data. The results from Chi-square test confirmed that there was statistically no significant difference(P =0.70) which provided assurance that the model was robust to estimate mean sojourn times. The key finding was that a patient entering the system in mild NPDR state is expected to stay in that state for 5y followed by 1.07 y in moderate NPDR, be in the severe NPDR state for 1.33 y before moving into PDR for roughly8 y. It is therefore expected that such a patient entering the model in a state of mild NPDR will enter blindness after 15.29 y.CONCLUSION: Patients stay for long time periods in mild NPDR before transitioning into moderate NPDR.However, they move rapidly from moderate NPDR to proliferative diabetic retinopathy(PDR) and stay in that state for long periods before transitioning into blindness.展开更多
Significant land-use changes in North Dakota have been reported and are widespread over the entire state. Such changing patterns may portend localized impairment to agricultural watersheds. In this study, Land-use Lan...Significant land-use changes in North Dakota have been reported and are widespread over the entire state. Such changing patterns may portend localized impairment to agricultural watersheds. In this study, Land-use Land-cover (LULC) change was modeled using geostatistics. The study area was within the Pipestem Creek watershed, a part of the Missouri Watershed James Subregion of North Dakota, USA. Landsat Thematic mapper images from the years 2007, 2011 and 2015 were used as preliminary data. LULC information for these datasets was acquired from the Global Land-cover facility and Landsat Program. Data analysis, spectral classification and post classification techniques were applied on the datasets. A transition matrix was derived using a Markov chain Monte Carlo (MCMC) model. This study demonstrates that the integration of satellite remote sensing, GIS and statistics may be an effective approach for analyzing the direction, rate, and spatial pattern of land-use change.展开更多
In this paper we consider a Markov chain model in an ATM network, which has been studied by Dag and Stavrakakis. On the basis of the iterative formulas obtained by Dag and Stavrakakis, we obtain the explicit analytica...In this paper we consider a Markov chain model in an ATM network, which has been studied by Dag and Stavrakakis. On the basis of the iterative formulas obtained by Dag and Stavrakakis, we obtain the explicit analytical expression of the transition probability matrix. It is very simple to calculate the transition probabilities of the Markov chain by these expressions. In addition, we obtain some results about the structure of the transition probability matrix, which are helpful in numerical calculation and theoretical analysis.展开更多
1 引言迭代函数系IFS(Iterated Function Systems),是混沌分形理论研究的一个重要部分,其理论与方法是分形自然景观模拟及分形图像压缩的理论基础。1985年,Williams和Hutchinson开创了分形几何中IFS的研究,建立了IFS的一般基础理论;M.F....1 引言迭代函数系IFS(Iterated Function Systems),是混沌分形理论研究的一个重要部分,其理论与方法是分形自然景观模拟及分形图像压缩的理论基础。1985年,Williams和Hutchinson开创了分形几何中IFS的研究,建立了IFS的一般基础理论;M.F.Barnsley和S.Demko的进一步工作使得这一方法成为构造任意维数分形集方便、有效的方法,并将之应用到图像的压缩与处理,使得该方法引起人们的关注。展开更多
文摘AIM: To study the natural progression of diabetic retinopathy in patients with type 2 diabetes.METHODS: This was an observational study of 153 cases with type 2 diabetes from 2010 to 2013. The state of patient was noted at end of each year and transition matrices were developed to model movement between years. Patients who progressed to severe non-proliferative diabetic retinopathy(NPDR) were treated.Markov Chains and Chi-square test were used for statistical analysis.RESULTS: We modelled the transition of 153 patients from NPDR to blindness on an annual basis. At the end of year 3, we compared results from the Markov model versus actual data. The results from Chi-square test confirmed that there was statistically no significant difference(P =0.70) which provided assurance that the model was robust to estimate mean sojourn times. The key finding was that a patient entering the system in mild NPDR state is expected to stay in that state for 5y followed by 1.07 y in moderate NPDR, be in the severe NPDR state for 1.33 y before moving into PDR for roughly8 y. It is therefore expected that such a patient entering the model in a state of mild NPDR will enter blindness after 15.29 y.CONCLUSION: Patients stay for long time periods in mild NPDR before transitioning into moderate NPDR.However, they move rapidly from moderate NPDR to proliferative diabetic retinopathy(PDR) and stay in that state for long periods before transitioning into blindness.
文摘Significant land-use changes in North Dakota have been reported and are widespread over the entire state. Such changing patterns may portend localized impairment to agricultural watersheds. In this study, Land-use Land-cover (LULC) change was modeled using geostatistics. The study area was within the Pipestem Creek watershed, a part of the Missouri Watershed James Subregion of North Dakota, USA. Landsat Thematic mapper images from the years 2007, 2011 and 2015 were used as preliminary data. LULC information for these datasets was acquired from the Global Land-cover facility and Landsat Program. Data analysis, spectral classification and post classification techniques were applied on the datasets. A transition matrix was derived using a Markov chain Monte Carlo (MCMC) model. This study demonstrates that the integration of satellite remote sensing, GIS and statistics may be an effective approach for analyzing the direction, rate, and spatial pattern of land-use change.
基金This work is supported by the National Key Project of China(No 970211017,the National Natural Science Foundation of China(No,10271102)and Hebei Province Doctoral Foundation(No.2002131)
文摘In this paper we consider a Markov chain model in an ATM network, which has been studied by Dag and Stavrakakis. On the basis of the iterative formulas obtained by Dag and Stavrakakis, we obtain the explicit analytical expression of the transition probability matrix. It is very simple to calculate the transition probabilities of the Markov chain by these expressions. In addition, we obtain some results about the structure of the transition probability matrix, which are helpful in numerical calculation and theoretical analysis.
文摘1 引言迭代函数系IFS(Iterated Function Systems),是混沌分形理论研究的一个重要部分,其理论与方法是分形自然景观模拟及分形图像压缩的理论基础。1985年,Williams和Hutchinson开创了分形几何中IFS的研究,建立了IFS的一般基础理论;M.F.Barnsley和S.Demko的进一步工作使得这一方法成为构造任意维数分形集方便、有效的方法,并将之应用到图像的压缩与处理,使得该方法引起人们的关注。
