The Eighth Five-year Plan period wasa fast growing period for Jiangsu’sforeign economic and technical co-operation. Guided by the policy of seizingopportunities, expanding the opening driveand promoting development, ...The Eighth Five-year Plan period wasa fast growing period for Jiangsu’sforeign economic and technical co-operation. Guided by the policy of seizingopportunities, expanding the opening driveand promoting development, all the staff atthe provincial foreign economic front madeevery effort to fulfill the goal of the sus-tained, fast and healthy development in for-展开更多
1.Introduction With the implementation of modern production strategies,such as“Industry 4.0”and“Made in China 2025,”the development of high-end mechanical equipment is gradually reaching a high degree of parameter...1.Introduction With the implementation of modern production strategies,such as“Industry 4.0”and“Made in China 2025,”the development of high-end mechanical equipment is gradually reaching a high degree of parameterization,digitalization,networking,and intelligence[1].High-end mechanical equipment no longer consists of traditional single devices,but is closely linked to the overall production process;that is,a variety of devices interact with each other and collectively form a complex system.However,faults can lead to production delays throughout the system and even seriously threaten the safety of workers[2].In addition,equipment operating in unmanned air or space vehicles(including space robots)cannot be repaired by humans if they break down[3].Until recently,the typical method of addressing machine faults was primarily the“fault cure”method,which involves manually shutting down,inspecting,and repairing the equipment to restore normal operation.Accordingly,the maintenance cycle of the traditional“fault cure”method is time-consuming,and the quality of the maintenance depends on the skills of the technician[4].展开更多
The Central Economic Work Conference was held in Beijing from December 11 to 12.The conference discussed the plans,prospects and challenges for China’s economy heading into 2024,as well as evaluating the events of th...The Central Economic Work Conference was held in Beijing from December 11 to 12.The conference discussed the plans,prospects and challenges for China’s economy heading into 2024,as well as evaluating the events of this year.It goes without saying that 2023 has been a challenging year for countries around the world as the global context has been unsatisfactory.Various geopolitical tensions have created a rise in uncertainties which have led to reduced growth worldwide and sent many economies into stagnation.In light of the critical factors affecting the stability of the global economy,China’s primary economic goal corresponds with the promotion and sustaining of free trade.展开更多
Metal-organic frameworks(MOFs) are becoming more and more popular as the fillers in polymer electrolytes in recent years. In this study, a series of MOFs(NH_(2)-MIL-101(Fe), MIL-101(Fe), activated NH_(2)-MIL-101(Fe) a...Metal-organic frameworks(MOFs) are becoming more and more popular as the fillers in polymer electrolytes in recent years. In this study, a series of MOFs(NH_(2)-MIL-101(Fe), MIL-101(Fe), activated NH_(2)-MIL-101(Fe) and activated MIL-101(Fe)) were synthesized and added to PEO-based solid composite electrolytes(SCEs). Furthermore, the role of the —NH_(2) groups and open metal sites(OMSs) were both examined. Different ratios of MOFs vs polymers were also studied by the electrochemical characterizations. At last, we successfully designed a novel solid composite electrolyte containing activated NH_(2)-MIL-101(Fe),PEO, Li TFSI and PVDF for the high-performance all-solid-state lithium-metal batteries. This work might provide new insight to understand the interactions between polymers and functional groups or OMSs of MOFs better.展开更多
Objective: Multiple alternative approaches of cochlear implant surgery have been described, such as the suprameatal approach, transcanal approach, transmeatal approach and middle cranial fossa approach.Transmeatal(ope...Objective: Multiple alternative approaches of cochlear implant surgery have been described, such as the suprameatal approach, transcanal approach, transmeatal approach and middle cranial fossa approach.Transmeatal(open trnascanal) approach has not been adapted since first described in the clinical field.we aimed to assess the long-term complications of the transmeatal approach in a series of 131 patients at our center between 2004 and 2008.Methods: This study was a retrospective case series of all patients who underwent cochlear implants with the transmeatal(open transcanal) approach from May 2004 to December 2008 at King Faisal Specialist and Research Hospital(Riyadh, Saudi Arabia), which were conducted by the same surgeon.Results: Complications were observed often with various combinations-recurrent otitis externa, posterior tympanic membrane perforation, electrode extrusion, cholesteatoma, and chronic mastoiditis. The overall long-term complication rate was 16%(21/131). The gap between the implantation and the diagnosis of a complication ranged from <1 year to 11 years. Major complications were as follows:cholesteatoma in 5(3.8%) patients, extrusion of the electrode in 5(3.8%) patients, and tympanic membrane perforation or deep retractions in 5(3.8%) patients. Minor complications were as follows: recurrent mastoiditis with/without concomitant temporary facial nerve palsy in 4(3%) patients, recurrent otitis externa infections in 7(5%) patients, and weakness of the posterior canal wall in 1 patient.Conclusion: The transmeatal approach posed an high rate of complications on long-term follow-up such as cholestetoma formation, extrusion of electrode or perielectrode reaction formation to tympanic membrane and external auditory canal.展开更多
Socialism with Chinese characteristics is a great cause full of vigor and vitality. The democratic politics with Chinese characteristics is a development process of constant exploration and innovation, both in theory ...Socialism with Chinese characteristics is a great cause full of vigor and vitality. The democratic politics with Chinese characteristics is a development process of constant exploration and innovation, both in theory and in practice. Since the 18th National Congress of the Communist Party of China(CPC)。展开更多
Over the past decade,China’s free trade zones have progressively formed a high-level innovation pattern of reform and opening-up in areas that extend from coastal regions to border provinces.They have become a leadin...Over the past decade,China’s free trade zones have progressively formed a high-level innovation pattern of reform and opening-up in areas that extend from coastal regions to border provinces.They have become a leading force of high-level opening-up,a pioneer of in-depth reform,and a major platform that serves the national strategy.As pilot platforms for comprehensive reform and opening-up,they are now taking on a more arduous mission.展开更多
Forty-five years on,China’s opening-up drive has raked in an accumulated foreign investment of US$2.9 trillion with more than 1 million foreign-funded firms established in the country.A raft of policies and measures ...Forty-five years on,China’s opening-up drive has raked in an accumulated foreign investment of US$2.9 trillion with more than 1 million foreign-funded firms established in the country.A raft of policies and measures have been rolled out for greater integration in globalization.China’s first pilot free trade zone(FTZ)in Shanghai’s Pudong New Area,established to undertake transformative reforms on a trial basis that could later be applied across the country,is also celebrating its 10th year.From that single pioneer,China today has 22 FTZs,and the Hainan Free Trade Port,which are all testbeds for advancing reform and opening-up.展开更多
The first session of the 14th National People’s Congress(NPC)of China held a press conference on March 13,wherein Chinese Premier Li Qiang met Chinese and foreign reporters and answered their questions.When asked abo...The first session of the 14th National People’s Congress(NPC)of China held a press conference on March 13,wherein Chinese Premier Li Qiang met Chinese and foreign reporters and answered their questions.When asked about the priorities of the new government,Premier Li stressed that reform and opening-up has been a crucial move that transformed China into what it is today.He also said that China would promote highlevel opening-up and inject stronger vitality into national development by deepening reform.展开更多
Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult...Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult decomposition of discharge products at present.Here,we have developed N-doped carbon anchored atomically dispersed Ru sites cathode catalyst with open hollow structure(h-RuNC)for Lithium–oxygen battery.On one hand,the abundance of atomically dispersed Ru sites can effectively catalyze the formation and decomposition of discharge products,thereby greatly enhancing the redox kinetics.On the other hand,the open hollow structure not only enhances the mass activity of atomically dispersed Ru sites but also improves the diffusion efficiency of catalytic molecules.Therefore,the excellent activity from atomically dispersed Ru sites and the enhanced diffusion from open hollow structure respectively improve the redox kinetics and cycling stability,ultimately achieving a high-performance lithium–oxygen battery.展开更多
Photoinduced intermolecular charge transfer(PICT)determines the voltage loss in bulk heterojunction(BHJ)organic photovoltaics(OPVs),and this voltage loss can be minimized by inducing efficient PICT,which requires ener...Photoinduced intermolecular charge transfer(PICT)determines the voltage loss in bulk heterojunction(BHJ)organic photovoltaics(OPVs),and this voltage loss can be minimized by inducing efficient PICT,which requires energy-state matching between the donor and acceptor at the BHJ interfaces.Thus,both geometrically and energetically accessible delocalized state matching at the hot energy level is crucial for achieving efficient PICT.In this study,an effective method for quantifying the hot state matching of OPVs was developed.The degree of energy-state matching between the electron donor and acceptor at BHJ interfaces was quantified using a mismatching factor(MF)calculated from the modified optical density of the BHJ.Furthermore,the correlation between the open-circuit voltage(Voc)of the OPV device and energy-state matching at the BHJ interface was investigated using the calculated MF.The OPVs with small absolute MF values exhibited high Voc values.This result clearly indicates that the energy-state matching between the donor and acceptor is crucial for achieving a high Voc in OPVs.Because the MF indicates the degree of energy-state matching,which is a critical factor for suppressing energy loss,it can be used to estimate the Voc loss in OPVs.展开更多
Purpose:Recently,global science has shown an increasing open trend,however,the characteristics of research integrity of open access(OA)publications have rarely been studied.The aim of this study is to compare the char...Purpose:Recently,global science has shown an increasing open trend,however,the characteristics of research integrity of open access(OA)publications have rarely been studied.The aim of this study is to compare the characteristics of retracted articles across different OA levels and discover whether OA level influences the characteristics of retracted articles.Design/methodology/approach:The research conducted an analysis of 6,005 retracted publications between 2001 and 2020 from the Web of Science and Retraction Watch databases.These publications were categorized based on their OA levels,including Gold OA,Green OA,and non-OA.The study explored retraction rates,time lags and reasons within these categories.Findings:The findings of this research revealed distinct patterns in retraction rates among different OA levels.Publications with Gold OA demonstrated the highest retraction rate,followed by Green OA and non-OA.A comparison of retraction reasons between Gold OA and non-OA categories indicated similar proportions,while Green OA exhibited a higher proportion due to falsification and manipulation issues,along with a lower occurrence of plagiarism and authorship issues.The retraction time lag was shortest for Gold OA,followed by non-OA,and longest for Green OA.The prolonged retraction time for Green OA could be attributed to an atypical distribution of retraction reasons.A comparative study on characteristics of retracted publications across different open access levels Research limitations:There is no exploration of a wider range of OA levels,such as Hybrid OA and Bronze OA.Practical implications:The outcomes of this study suggest the need for increased attention to research integrity within the OA publications.The occurrences offalsification,manipulation,and ethical concerns within Green OA publications warrant attention from the scientific community.Originality/value:This study contributes to the understanding of research integrity in the realm of OA publications,shedding light on retraction patterns and reasons across different OA levels.展开更多
Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled a...Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled and randomly divided into two groups.Patients in the control group were treated with polysaccharide-iron complex,and those in the experimental group were administered Jianpi Shengxue tablet.After 8 weeks of continuous treatment,the therapeutic outcomes regarding anemia were compared between the two groups.Results After treatment,the red blood cell(RBC)count,hematocrit(HCT),reticulocyte percentage(RET),ferritin(SF),serum iron(SI),transferrin saturation(TSAT),and serum albumin(ALB)all increased(P<0.01),and the clinical symptom score and total iron binding capacity decreased(P<0.01)in the experimental group.Moreover,the improvements in RBC,HCT,RET,SF,SI,TAST,ALB,and clinical symptoms(fatigue,anorexia,dull skin complexion,numbness of hands and feet)in the experimental group were significantly greater than those in the control group(P<0.05).The total effective rate for treating renal anemia was significantly higher in the experimental group than in the control group(P<0.01).Conclusion The Jianpi Shengxue tablet demonstrates efficacy in treating renal anemia,leading to significant improvements in the laboratory examination results and clinical symptoms of patients with renal anemia.展开更多
Background:Our clinical practice of laparoscopic liver resection(LLR)had achieved better short-term and long-term benefits for patients with hepatocellular carcinoma(HCC)over open liver resection(OLR),but the underlyi...Background:Our clinical practice of laparoscopic liver resection(LLR)had achieved better short-term and long-term benefits for patients with hepatocellular carcinoma(HCC)over open liver resection(OLR),but the underlying mechanisms are not clear.This study was to find out whether systemic inflammation plays an important role.Methods:A total of 103 patients with early-stage HCC under liver resection were enrolled(LLR group,n=53;OLR group,n=50).The expression of 9 inflammatory cytokines in patients at preoperation,postoperative day 1(POD1)and POD7 was quantified by Luminex Multiplex assay.The relationships of the cytokines and the postoperative outcomes were compared between LLR and OLR.Results:Seven of the circulating cytokines were found to be significantly upregulated on POD1 after LLR or OLR compared to their preoperative levels.Compared to OLR,the POD1 levels of granulocytemacrophage colony-stimulating factor(GM-CSF),interleukin-6(IL-6),IL-8,and monocyte chemoattractant protein-1(MCP-1)in the LLR group were significantly lower.Higher POD1 levels of these cytokines were significantly correlated with longer operative time and higher volume of blood loss during operation.The levels of these cytokines were positively associated with postoperative liver injury,and the length of hospital stay.Importantly,a high level of IL-6 at POD1 was a risk factor for HCC recurrence and poor disease-free survival after liver resection.Conclusions:Significantly lower level of GM-CSF,IL-6,IL-8,and MCP-1 after liver resection represented a milder systemic inflammation which might be an important mechanism to offer better short-term and long-term outcomes in LLR over OLR.展开更多
This paper proposes a novel open set recognition method,the Spatial Distribution Feature Extraction Network(SDFEN),to address the problem of electromagnetic signal recognition in an open environment.The spatial distri...This paper proposes a novel open set recognition method,the Spatial Distribution Feature Extraction Network(SDFEN),to address the problem of electromagnetic signal recognition in an open environment.The spatial distribution feature extraction layer in SDFEN replaces convolutional output neural networks with the spatial distribution features that focus more on inter-sample information by incorporating class center vectors.The designed hybrid loss function considers both intra-class distance and inter-class distance,thereby enhancing the similarity among samples of the same class and increasing the dissimilarity between samples of different classes during training.Consequently,this method allows unknown classes to occupy a larger space in the feature space.This reduces the possibility of overlap with known class samples and makes the boundaries between known and unknown samples more distinct.Additionally,the feature comparator threshold can be used to reject unknown samples.For signal open set recognition,seven methods,including the proposed method,are applied to two kinds of electromagnetic signal data:modulation signal and real-world emitter.The experimental results demonstrate that the proposed method outperforms the other six methods overall in a simulated open environment.Specifically,compared to the state-of-the-art Openmax method,the novel method achieves up to 8.87%and 5.25%higher micro-F-measures,respectively.展开更多
文摘The Eighth Five-year Plan period wasa fast growing period for Jiangsu’sforeign economic and technical co-operation. Guided by the policy of seizingopportunities, expanding the opening driveand promoting development, all the staff atthe provincial foreign economic front madeevery effort to fulfill the goal of the sus-tained, fast and healthy development in for-
基金supported by Natural Science Foundation of Beijing(3212010)National Natural Science Foundation of China(51875031 and 52242507).
文摘1.Introduction With the implementation of modern production strategies,such as“Industry 4.0”and“Made in China 2025,”the development of high-end mechanical equipment is gradually reaching a high degree of parameterization,digitalization,networking,and intelligence[1].High-end mechanical equipment no longer consists of traditional single devices,but is closely linked to the overall production process;that is,a variety of devices interact with each other and collectively form a complex system.However,faults can lead to production delays throughout the system and even seriously threaten the safety of workers[2].In addition,equipment operating in unmanned air or space vehicles(including space robots)cannot be repaired by humans if they break down[3].Until recently,the typical method of addressing machine faults was primarily the“fault cure”method,which involves manually shutting down,inspecting,and repairing the equipment to restore normal operation.Accordingly,the maintenance cycle of the traditional“fault cure”method is time-consuming,and the quality of the maintenance depends on the skills of the technician[4].
文摘The Central Economic Work Conference was held in Beijing from December 11 to 12.The conference discussed the plans,prospects and challenges for China’s economy heading into 2024,as well as evaluating the events of this year.It goes without saying that 2023 has been a challenging year for countries around the world as the global context has been unsatisfactory.Various geopolitical tensions have created a rise in uncertainties which have led to reduced growth worldwide and sent many economies into stagnation.In light of the critical factors affecting the stability of the global economy,China’s primary economic goal corresponds with the promotion and sustaining of free trade.
基金financially supported by National Natural Science Foundation of China (21701083)Postgraduate Research & Practice Innovation Program of Jiangsu Province (KYCX20_3137)。
文摘Metal-organic frameworks(MOFs) are becoming more and more popular as the fillers in polymer electrolytes in recent years. In this study, a series of MOFs(NH_(2)-MIL-101(Fe), MIL-101(Fe), activated NH_(2)-MIL-101(Fe) and activated MIL-101(Fe)) were synthesized and added to PEO-based solid composite electrolytes(SCEs). Furthermore, the role of the —NH_(2) groups and open metal sites(OMSs) were both examined. Different ratios of MOFs vs polymers were also studied by the electrochemical characterizations. At last, we successfully designed a novel solid composite electrolyte containing activated NH_(2)-MIL-101(Fe),PEO, Li TFSI and PVDF for the high-performance all-solid-state lithium-metal batteries. This work might provide new insight to understand the interactions between polymers and functional groups or OMSs of MOFs better.
文摘Objective: Multiple alternative approaches of cochlear implant surgery have been described, such as the suprameatal approach, transcanal approach, transmeatal approach and middle cranial fossa approach.Transmeatal(open trnascanal) approach has not been adapted since first described in the clinical field.we aimed to assess the long-term complications of the transmeatal approach in a series of 131 patients at our center between 2004 and 2008.Methods: This study was a retrospective case series of all patients who underwent cochlear implants with the transmeatal(open transcanal) approach from May 2004 to December 2008 at King Faisal Specialist and Research Hospital(Riyadh, Saudi Arabia), which were conducted by the same surgeon.Results: Complications were observed often with various combinations-recurrent otitis externa, posterior tympanic membrane perforation, electrode extrusion, cholesteatoma, and chronic mastoiditis. The overall long-term complication rate was 16%(21/131). The gap between the implantation and the diagnosis of a complication ranged from <1 year to 11 years. Major complications were as follows:cholesteatoma in 5(3.8%) patients, extrusion of the electrode in 5(3.8%) patients, and tympanic membrane perforation or deep retractions in 5(3.8%) patients. Minor complications were as follows: recurrent mastoiditis with/without concomitant temporary facial nerve palsy in 4(3%) patients, recurrent otitis externa infections in 7(5%) patients, and weakness of the posterior canal wall in 1 patient.Conclusion: The transmeatal approach posed an high rate of complications on long-term follow-up such as cholestetoma formation, extrusion of electrode or perielectrode reaction formation to tympanic membrane and external auditory canal.
文摘Socialism with Chinese characteristics is a great cause full of vigor and vitality. The democratic politics with Chinese characteristics is a development process of constant exploration and innovation, both in theory and in practice. Since the 18th National Congress of the Communist Party of China(CPC)。
文摘Over the past decade,China’s free trade zones have progressively formed a high-level innovation pattern of reform and opening-up in areas that extend from coastal regions to border provinces.They have become a leading force of high-level opening-up,a pioneer of in-depth reform,and a major platform that serves the national strategy.As pilot platforms for comprehensive reform and opening-up,they are now taking on a more arduous mission.
文摘Forty-five years on,China’s opening-up drive has raked in an accumulated foreign investment of US$2.9 trillion with more than 1 million foreign-funded firms established in the country.A raft of policies and measures have been rolled out for greater integration in globalization.China’s first pilot free trade zone(FTZ)in Shanghai’s Pudong New Area,established to undertake transformative reforms on a trial basis that could later be applied across the country,is also celebrating its 10th year.From that single pioneer,China today has 22 FTZs,and the Hainan Free Trade Port,which are all testbeds for advancing reform and opening-up.
文摘The first session of the 14th National People’s Congress(NPC)of China held a press conference on March 13,wherein Chinese Premier Li Qiang met Chinese and foreign reporters and answered their questions.When asked about the priorities of the new government,Premier Li stressed that reform and opening-up has been a crucial move that transformed China into what it is today.He also said that China would promote highlevel opening-up and inject stronger vitality into national development by deepening reform.
基金This work was supported by National Key R&D Program of China(2021YFF0500503)National Natural Science Foundation of China(21925202,U22B2071)International Joint Mission on Climate Change and Carbon Neutrality.
文摘Lithium–oxygen battery with ultrahigh theoretical energy density is considered a highly competitive next-generation energy storage device,but its practical application is severely hindered by issues such as difficult decomposition of discharge products at present.Here,we have developed N-doped carbon anchored atomically dispersed Ru sites cathode catalyst with open hollow structure(h-RuNC)for Lithium–oxygen battery.On one hand,the abundance of atomically dispersed Ru sites can effectively catalyze the formation and decomposition of discharge products,thereby greatly enhancing the redox kinetics.On the other hand,the open hollow structure not only enhances the mass activity of atomically dispersed Ru sites but also improves the diffusion efficiency of catalytic molecules.Therefore,the excellent activity from atomically dispersed Ru sites and the enhanced diffusion from open hollow structure respectively improve the redox kinetics and cycling stability,ultimately achieving a high-performance lithium–oxygen battery.
基金National Research Foundation of Korea,Grant/Award Number:2022R1A6A1A03051158BrainLink Program,Grant/Award Number:2022H1D3A3A01077343Nano Material Technology Development Program,Grant/Award Number:2021M3H4A1A02057007。
文摘Photoinduced intermolecular charge transfer(PICT)determines the voltage loss in bulk heterojunction(BHJ)organic photovoltaics(OPVs),and this voltage loss can be minimized by inducing efficient PICT,which requires energy-state matching between the donor and acceptor at the BHJ interfaces.Thus,both geometrically and energetically accessible delocalized state matching at the hot energy level is crucial for achieving efficient PICT.In this study,an effective method for quantifying the hot state matching of OPVs was developed.The degree of energy-state matching between the electron donor and acceptor at BHJ interfaces was quantified using a mismatching factor(MF)calculated from the modified optical density of the BHJ.Furthermore,the correlation between the open-circuit voltage(Voc)of the OPV device and energy-state matching at the BHJ interface was investigated using the calculated MF.The OPVs with small absolute MF values exhibited high Voc values.This result clearly indicates that the energy-state matching between the donor and acceptor is crucial for achieving a high Voc in OPVs.Because the MF indicates the degree of energy-state matching,which is a critical factor for suppressing energy loss,it can be used to estimate the Voc loss in OPVs.
基金the National Social Science Foundation of China(No.22CTQ032).
文摘Purpose:Recently,global science has shown an increasing open trend,however,the characteristics of research integrity of open access(OA)publications have rarely been studied.The aim of this study is to compare the characteristics of retracted articles across different OA levels and discover whether OA level influences the characteristics of retracted articles.Design/methodology/approach:The research conducted an analysis of 6,005 retracted publications between 2001 and 2020 from the Web of Science and Retraction Watch databases.These publications were categorized based on their OA levels,including Gold OA,Green OA,and non-OA.The study explored retraction rates,time lags and reasons within these categories.Findings:The findings of this research revealed distinct patterns in retraction rates among different OA levels.Publications with Gold OA demonstrated the highest retraction rate,followed by Green OA and non-OA.A comparison of retraction reasons between Gold OA and non-OA categories indicated similar proportions,while Green OA exhibited a higher proportion due to falsification and manipulation issues,along with a lower occurrence of plagiarism and authorship issues.The retraction time lag was shortest for Gold OA,followed by non-OA,and longest for Green OA.The prolonged retraction time for Green OA could be attributed to an atypical distribution of retraction reasons.A comparative study on characteristics of retracted publications across different open access levels Research limitations:There is no exploration of a wider range of OA levels,such as Hybrid OA and Bronze OA.Practical implications:The outcomes of this study suggest the need for increased attention to research integrity within the OA publications.The occurrences offalsification,manipulation,and ethical concerns within Green OA publications warrant attention from the scientific community.Originality/value:This study contributes to the understanding of research integrity in the realm of OA publications,shedding light on retraction patterns and reasons across different OA levels.
基金financially supported by the National Natural Science Foundation of China(No.82170701).
文摘Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled and randomly divided into two groups.Patients in the control group were treated with polysaccharide-iron complex,and those in the experimental group were administered Jianpi Shengxue tablet.After 8 weeks of continuous treatment,the therapeutic outcomes regarding anemia were compared between the two groups.Results After treatment,the red blood cell(RBC)count,hematocrit(HCT),reticulocyte percentage(RET),ferritin(SF),serum iron(SI),transferrin saturation(TSAT),and serum albumin(ALB)all increased(P<0.01),and the clinical symptom score and total iron binding capacity decreased(P<0.01)in the experimental group.Moreover,the improvements in RBC,HCT,RET,SF,SI,TAST,ALB,and clinical symptoms(fatigue,anorexia,dull skin complexion,numbness of hands and feet)in the experimental group were significantly greater than those in the control group(P<0.05).The total effective rate for treating renal anemia was significantly higher in the experimental group than in the control group(P<0.01).Conclusion The Jianpi Shengxue tablet demonstrates efficacy in treating renal anemia,leading to significant improvements in the laboratory examination results and clinical symptoms of patients with renal anemia.
基金This study was supported by Shenzhen Fundamental Research Program-General Program(No.JCYJ20210324114403010).
文摘Background:Our clinical practice of laparoscopic liver resection(LLR)had achieved better short-term and long-term benefits for patients with hepatocellular carcinoma(HCC)over open liver resection(OLR),but the underlying mechanisms are not clear.This study was to find out whether systemic inflammation plays an important role.Methods:A total of 103 patients with early-stage HCC under liver resection were enrolled(LLR group,n=53;OLR group,n=50).The expression of 9 inflammatory cytokines in patients at preoperation,postoperative day 1(POD1)and POD7 was quantified by Luminex Multiplex assay.The relationships of the cytokines and the postoperative outcomes were compared between LLR and OLR.Results:Seven of the circulating cytokines were found to be significantly upregulated on POD1 after LLR or OLR compared to their preoperative levels.Compared to OLR,the POD1 levels of granulocytemacrophage colony-stimulating factor(GM-CSF),interleukin-6(IL-6),IL-8,and monocyte chemoattractant protein-1(MCP-1)in the LLR group were significantly lower.Higher POD1 levels of these cytokines were significantly correlated with longer operative time and higher volume of blood loss during operation.The levels of these cytokines were positively associated with postoperative liver injury,and the length of hospital stay.Importantly,a high level of IL-6 at POD1 was a risk factor for HCC recurrence and poor disease-free survival after liver resection.Conclusions:Significantly lower level of GM-CSF,IL-6,IL-8,and MCP-1 after liver resection represented a milder systemic inflammation which might be an important mechanism to offer better short-term and long-term outcomes in LLR over OLR.
文摘This paper proposes a novel open set recognition method,the Spatial Distribution Feature Extraction Network(SDFEN),to address the problem of electromagnetic signal recognition in an open environment.The spatial distribution feature extraction layer in SDFEN replaces convolutional output neural networks with the spatial distribution features that focus more on inter-sample information by incorporating class center vectors.The designed hybrid loss function considers both intra-class distance and inter-class distance,thereby enhancing the similarity among samples of the same class and increasing the dissimilarity between samples of different classes during training.Consequently,this method allows unknown classes to occupy a larger space in the feature space.This reduces the possibility of overlap with known class samples and makes the boundaries between known and unknown samples more distinct.Additionally,the feature comparator threshold can be used to reject unknown samples.For signal open set recognition,seven methods,including the proposed method,are applied to two kinds of electromagnetic signal data:modulation signal and real-world emitter.The experimental results demonstrate that the proposed method outperforms the other six methods overall in a simulated open environment.Specifically,compared to the state-of-the-art Openmax method,the novel method achieves up to 8.87%and 5.25%higher micro-F-measures,respectively.