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Non-Linear Matrix Completion
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作者 Fengrui Zhang Randy C. Paffenroth David Worth 《Journal of Data Analysis and Information Processing》 2024年第1期115-137,共23页
Current methods for predicting missing values in datasets often rely on simplistic approaches such as taking median value of attributes, limiting their applicability. Real-world observations can be diverse, taking sto... Current methods for predicting missing values in datasets often rely on simplistic approaches such as taking median value of attributes, limiting their applicability. Real-world observations can be diverse, taking stock price as example, ranging from prices post-IPO to values before a company’s collapse, or instances where certain data points are missing due to stock suspension. In this paper, we propose a novel approach using Nonlinear Matrix Completion (NIMC) and Deep Matrix Completion (DIMC) to predict associations, and conduct experiment on financial data between dates and stocks. Our method leverages various types of stock observations to capture latent factors explaining the observed date-stock associations. Notably, our approach is nonlinear, making it suitable for datasets with nonlinear structures, such as the Russell 3000. Unlike traditional methods that may suffer from information loss, NIMC and DIMC maintain nearly complete information, especially in high-dimensional parameters. We compared our approach with state-of-the-art linear methods, including Inductive Matrix Completion, Nonlinear Inductive Matrix Completion, and Deep Inductive Matrix Completion. Our findings show that the nonlinear matrix completion method is particularly effective for handling nonlinear structured data, as exemplified by the Russell 3000. Additionally, we validate the information loss of the three methods across different dimensionalities. 展开更多
关键词 Matrix completion Data Pipeline Machine Learning
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5G Ultra-Dense Network Fingerprint Positioning Method Based on Matrix Completion 被引量:1
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作者 Yuexia Zhang Chong Liu 《China Communications》 SCIE CSCD 2023年第3期105-118,共14页
The problem of high-precision indoor positioning in the 5G era has attracted more and more attention.A fingerprint location method based on matrix completion(MC-FPL)is proposed for 5G ultradense networks to overcome t... The problem of high-precision indoor positioning in the 5G era has attracted more and more attention.A fingerprint location method based on matrix completion(MC-FPL)is proposed for 5G ultradense networks to overcome the high costs of traditional fingerprint database construction and matching algorithms.First,a partial fingerprint database constructed and the accelerated proximal gradient algorithm is used to fill the partial fingerprint database to construct a full fingerprint database.Second,a fingerprint database division method based on the strongest received signal strength indicator is proposed,which divides the original fingerprint database into several sub-fingerprint databases.Finally,a classification weighted K-nearest neighbor fingerprint matching algorithm is proposed.The estimated coordinates of the point to be located can be obtained by fingerprint matching in a sub-fingerprint database.The simulation results show that the MC-FPL algorithm can reduce the complexity of database construction and fingerprint matching and has higher positioning accuracy compared with the traditional fingerprint algorithm. 展开更多
关键词 indoor positioning fingerprint matching matrix completion 5G UDN RSSI
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Next Words Prediction and Sentence Completion in Bangla Language Using GRU-Based RNN on N-Gram Language Model
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作者 Afranul Hoque Busrat Jahan +3 位作者 Shaikat Chandra Paul Zinat Ara Zabu Rakhi Mondal Papeya Akter 《Journal of Data Analysis and Information Processing》 2023年第4期388-399,共12页
We use a lot of devices in our daily life to communicate with others. In this modern world, people use email, Facebook, Twitter, and many other social network sites for exchanging information. People lose their valuab... We use a lot of devices in our daily life to communicate with others. In this modern world, people use email, Facebook, Twitter, and many other social network sites for exchanging information. People lose their valuable time misspelling and retyping, and some people are not happy to type large sentences because they face unnecessary words or grammatical issues. So, for this reason, word predictive systems help to exchange textual information more quickly, easier, and comfortably for all people. These systems predict the next most probable words and give users to choose of the needed word from these suggested words. Word prediction can help the writer by predicting the next word and helping complete the sentence correctly. This research aims to forecast the most suitable next word to complete a sentence for any given context. In this research, we have worked on the Bangla language. We have presented a process that can expect the next maximum probable and proper words and suggest a complete sentence using predicted words. In this research, GRU-based RNN has been used on the N-gram dataset to develop the proposed model. We collected a large dataset using multiple sources in the Bangla language and also compared it to the other approaches that have been used such as LSTM, and Naive Bayes. But this suggested approach provides excellent exactness than others. Here, the Unigram model provides 88.22%, Bi-gram model is 99.24%, Tri-gram model is 97.69%, and 4-gram and 5-gram models provide 99.43% and 99.78% on average accurateness. We think that our proposed method profound impression on Bangla search engines. 展开更多
关键词 Bangla Language Words Prediction Sentence completion GRU RNN Corpus N-Gram
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Completion of 6-mo isoniazid preventive treatment among eligible under six children:A cross-sectional study,Lagos,Nigeria
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作者 Victor Abiola Adepoju Ademola Adelekan +4 位作者 Aderonke Agbaje Femi Quaitey Tobi Ademola-Kay Ann Uduak Udoekpo Olusola Daniel Sokoya 《World Journal of Clinical Cases》 SCIE 2023年第1期104-115,共12页
BACKGROUND Nigeria is one of the thirty high burden countries with significant contribution to the global childhood tuberculosis epidemic.Tuberculosis annual risk for children could be as high as 4%particularly in hig... BACKGROUND Nigeria is one of the thirty high burden countries with significant contribution to the global childhood tuberculosis epidemic.Tuberculosis annual risk for children could be as high as 4%particularly in high tuberculosis(TB)prevalent communities.Isoniazid(INH)Preventive Therapy has been shown to prevent TB incidence but data on its implementation among children are scarce.AIM To determine the completion of INH among under six children that were exposed to adults with smear positive pulmonary TB in Lagos,Nigeria.METHODS This was a hospital-based retrospective cross-sectional review of 265 medical records of eligible children<6 years old enrolled for INH across 32 private hospitals in Lagos,Nigeria.The study took place between July and September 2020.Data was collected on independent variables(age,gender,type of facility,TB screening,dose and weight)and outcome variables(INH outcome and proportion lost to follow up across months 1-6 of INH treatment).RESULTS About 53.8%of the participants were female,95.4%were screened for TB and none was diagnosed of having TB.The participants’age ranged from 1 to 72 mo with a mean of 36.01±19.67 mo,and 40.2%were between the ages of 1-24 mo.Only 155(59.2%)of the 262 participants initiated on INH completed the six-month treatment.Cumulatively,107(41.0%)children were lost to follow-up at the end of the sixth month.Of the cumulative 107 loss to follow-up while on INH,largest drop-offs were reported at the end of month 2,52(49%)followed by 20(19%),17(16%),11(10.2%)and 7(6.5%)at months 3,4,5 and 6 respectively.The analysis showed that there was no significant association between age,gender,type of facility and completion of INH treatment(P>0.005).CONCLUSION This study demonstrated suboptimal INH completion rate among children with only 6 out of 10 children initiated on INH who completed a 6-mo treatment in Lagos,Nigeria.The huge drop-offs in the first 2 mo of INH calls for innovative strategies such as the use of 60-d INH calendar that would facilitate reminder and early engagement of children on INH and their caregivers in care and across the entire period of treatment. 展开更多
关键词 ISONIAZID CHILD TUBERCULOSIS Treatment Outcome completion Latent tuberculosis DOSAGE
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High-temperature corrosion of phosphate completion fluid and corrosion inhibition method by membrane transformation
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作者 JIA Hu HE Wei NIU Chengcheng 《Petroleum Exploration and Development》 SCIE 2023年第6期1497-1508,共12页
By analyzing the corrosion of phosphate completion fluid on the P110 steel at 170 °C, the high-temperature corrosion mechanism of phosphate completion fluid was revealed, and a corrosion inhibition method by memb... By analyzing the corrosion of phosphate completion fluid on the P110 steel at 170 °C, the high-temperature corrosion mechanism of phosphate completion fluid was revealed, and a corrosion inhibition method by membrane transformation was proposed and an efficient membrane-forming agent was selected. Scanning electron microscope (SEM) images, X-ray energy spectrum and X-ray diffraction results were used to characterize the microscopic morphology, elemental composition and phase composition of the precipitation membrane on the surface of the test piece. The effect and mechanism of corrosion inhibition by membrane transformation were clarified. The phosphate completion fluid eroded the test piece by high-temperature water vapor and its hydrolyzed products to form a membrane of iron phosphate corrosion product. By changing the corrosion reaction path, the Zn2+ membrane-forming agent could generate KZnPO4 precipitation membrane with high temperature resistance, uniform thickness and tight crystal packing on the surface of the test piece, which could inhibit the corrosion of the test piece, with efficiency up to 69.63%. The Cu2+ membrane-forming agent electrochemically reacted with Fe to precipitate trace elemental Cu on the surface of the test piece, thus forming a protective membrane, which could inhibit metal corrosion, with efficiency up to 96.64%, but the wear resistance was poor. After combining 0.05% Cu2+ and 0.25% Zn2+, a composite protective membrane of KZnPO4 crystal and elemental Cu was formed on the surface of the test piece. The corrosion inhibition efficiency reached 93.03%, which ensured the high corrosion inhibition efficiency and generated a precipitation membrane resistant to temperature and wear. 展开更多
关键词 phosphate completion fluid corrosion mechanism membrane transformation corrosion inhibition mechanism
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Aquatic Medicine Knowledge Graph Completion Based on Hybrid Convolution
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作者 Huining Yang Qishu Song +3 位作者 Liming Shao Guangyu Li Zhetao Sun Hong Yu 《Journal of Beijing Institute of Technology》 EI CAS 2023年第3期298-312,共15页
Aquatic medicine knowledge graph is an effective means to realize intelligent aquaculture.Graph completion technology is key to improving the quality of knowledge graph construction.However,the difficulty of semantic ... Aquatic medicine knowledge graph is an effective means to realize intelligent aquaculture.Graph completion technology is key to improving the quality of knowledge graph construction.However,the difficulty of semantic discrimination among similar entities and inconspicuous semantic features result in low accuracy when completing aquatic medicine knowledge graph with complex relationships.In this study,an aquatic medicine knowledge graph completion method(TransH+HConvAM)is proposed.Firstly,TransH is applied to split the vector plane between entities and relations,ameliorating the poor completion effect caused by low semantic resolution of entities.Then,hybrid convolution is introduced to obtain the global interaction of triples based on the complete interaction between head/tail entities and relations,which improves the semantic features of triples and enhances the completion effect of complex relationships in the graph.Experiments are conducted to verify the performance of the proposed method.The MR,MRR and Hit@10 of the TransH+HConvAM are found to be 674,0.339,and 0.361,respectively.This study shows that the model effectively overcomes the poor completion effect of complex relationships and improves the construction quality of the aquatic medicine knowledge graph,providing technical support for intelligent aquaculture. 展开更多
关键词 aquatic medicine knowledge graph graph completion hybrid convolution global features
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Design and feasibility analysis of a new completion monitoring technical scheme for natural gas hydrate production tests
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作者 Qiu-ping Lu Yan-jiang Yu +8 位作者 Xie Wen-wei Jin-qiang Liang Jing-an Lu Ben-chong Xu Hao-xian Shi Hao-yu Yu Ru-lei Qin Xing-chen Li Bin Li 《China Geology》 CAS CSCD 2023年第3期466-475,共10页
As a prerequisite and a guarantee for safe and efficient natural gas hydrates(NGHs)exploitation,it is imperative to effectively determine the mechanical properties of NGHs reservoirs and clarify the law of the change ... As a prerequisite and a guarantee for safe and efficient natural gas hydrates(NGHs)exploitation,it is imperative to effectively determine the mechanical properties of NGHs reservoirs and clarify the law of the change in the mechanical properties with the dissociation of NGHs during NGHs production tests by depressurization.Based on the development of Japan’s two offshore NGHs production tests in vertical wells,this study innovatively proposed a new subsea communication technology-accurate directional connection using a wet-mate connector.This helps to overcome the technical barrier to the communication between the upper and lower completion of offshore wells.Using this new communication technology,this study explored and designed a mechanical monitoring scheme for lower completion(sand screens).This scheme can be used to monitor the tensile stress and radial compressive stress of sand screens caused by NGHs reservoirs in real time,thus promoting the technical development for the rapid assessment and real-time feedback of the in-situ mechanical response of NGHs reservoirs during offshore NGHs production tests by depressurization. 展开更多
关键词 Natural gas hydrates Depressurization test Wet-mate Directional connection Lower completion monitoring In-situ mechanical response of reservoirs Oil-gas exploration engineering The South China Sea
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Classification of knowledge graph completeness measurement techniques
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作者 ZHANG Ying XIAO Gang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2024年第1期154-162,共9页
At present,although knowledge graphs have been widely used in various fields such as recommendation systems,question and answer systems,and intelligent search,there are always quality problems such as knowledge omissi... At present,although knowledge graphs have been widely used in various fields such as recommendation systems,question and answer systems,and intelligent search,there are always quality problems such as knowledge omissions and errors.Quality assessment and control,as an important means to ensure the quality of knowledge,can make the applications based on knowledge graphs more complete and more accurate by reasonably assessing the knowledge graphs and fixing and improving the quality problems at the same time.Therefore,as an indispensable part of the knowledge graph construction process,the results of quality assessment and control determine the usefulness of the knowledge graph.Among them,the assessment and enhancement of completeness,as an important part of the assessment and control phase,determine whether the knowledge graph can fully reflect objective phenomena and reveal potential connections among entities.In this paper,we review specific techniques of completeness assessment and classify completeness assessment techniques in terms of closed world assumptions,open world assumptions,and partial completeness assumptions.The purpose of this paper is to further promote the development of knowledge graph quality control and to lay the foundation for subsequent research on the completeness assessment of knowledge graphs by reviewing and classifying completeness assessment techniques. 展开更多
关键词 quality assessment completeness assessment closed world assumptions open world assumption partial completeness assumption
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Passability test and simulation of sand control string with natural gas hydrates completion in large curvature hole
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作者 Hao-xian Shi Yan-jiang Yu +12 位作者 Ru-lei Qin Jun-yu Deng Yi-xin Zhong Li-qiang Qi Bin Li Bo Fan Qiu-ping Lu Jian Wang Kui-wei Li Ye-cheng Gan Gen-long Chen Hao-wen Chen Zhi-ming Wu 《China Geology》 CAS CSCD 2023年第1期27-36,共10页
To meet the requirements of marine natural gas hydrate exploitation,it is necessary to improve the penetration of completion sand control string in the large curvature borehole.In this study,large curvature test wells... To meet the requirements of marine natural gas hydrate exploitation,it is necessary to improve the penetration of completion sand control string in the large curvature borehole.In this study,large curvature test wells were selected to carry out the running test of sand control string with pre-packed screen.Meanwhile,the running simulation was performed by using the Landmark software.The results show that the sand control packer and screen can be run smoothly in the wellbore with a dogleg angle of more than 20°/30 m and keep the structure stable.Additionally,the comprehensive friction coefficient is 0.4,under which and the simulation shows that the sand control string for hydrate exploitation can be run smoothly.These findings have important guiding significance for running the completion sand control string in natural gas hydrate exploitation. 展开更多
关键词 Natural gas hydrates(NGHs) completion sand control string Large curvature borehole Passability test Friction coefficient Oil and gas exploration engineering NGHs exploration trial engineering
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Regenerative medicine strategies for chronic complete spinal cord injury
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作者 Shogo Hashimoto Narihito Nagoshi +1 位作者 Masaya Nakamura Hideyuki Okano 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第4期818-824,共7页
Spinal cord injury is a condition in which the parenchyma of the spinal cord is damaged by trauma or various diseases.While rapid progress has been made in regenerative medicine for spinal cord injury that was previou... Spinal cord injury is a condition in which the parenchyma of the spinal cord is damaged by trauma or various diseases.While rapid progress has been made in regenerative medicine for spinal cord injury that was previously untreatable,most research in this field has focused on the early phase of incomplete injury.However,the majority of patients have chronic severe injuries;therefore,treatments for these situations are of fundamental importance.The reason why the treatment of complete spinal cord injury has not been studied is that,unlike in the early stage of incomplete spinal cord injury,there are various inhibitors of neural regeneration.Thus,we assumed that it is difficult to address all conditions with a single treatment in chronic complete spinal cord injury and that a combination of several treatments is essential to target severe pathologies.First,we established a combination therapy of cell transplantation and drug-releasing scaffolds,which contributes to functional recovery after chronic complete transection spinal cord injury,but we found that functional recovery was limited and still needs further investigation.Here,for the further development of the treatment of chronic complete spinal cord injury,we review the necessary approaches to the different pathologies based on our findings and the many studies that have been accumulated to date and discuss,with reference to the literature,which combination of treatments is most effective in achieving functional recovery. 展开更多
关键词 cell transplantation chronic phase complete transection regenerative medicine spinal cord injury
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Distributed collaborative complete coverage path planning based on hybrid strategy
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作者 ZHANG Jia DU Xin +1 位作者 DONG Qichen XIN Bin 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第2期463-472,共10页
Collaborative coverage path planning(CCPP) refers to obtaining the shortest paths passing over all places except obstacles in a certain area or space. A multi-unmanned aerial vehicle(UAV) collaborative CCPP algorithm ... Collaborative coverage path planning(CCPP) refers to obtaining the shortest paths passing over all places except obstacles in a certain area or space. A multi-unmanned aerial vehicle(UAV) collaborative CCPP algorithm is proposed for the urban rescue search or military search in outdoor environment.Due to flexible control of small UAVs, it can be considered that all UAVs fly at the same altitude, that is, they perform search tasks on a two-dimensional plane. Based on the agents’ motion characteristics and environmental information, a mathematical model of CCPP problem is established. The minimum time for UAVs to complete the CCPP is the objective function, and complete coverage constraint, no-fly constraint, collision avoidance constraint, and communication constraint are considered. Four motion strategies and two communication strategies are designed. Then a distributed CCPP algorithm is designed based on hybrid strategies. Simulation results compared with patternbased genetic algorithm(PBGA) and random search method show that the proposed method has stronger real-time performance and better scalability and can complete the complete CCPP task more efficiently and stably. 展开更多
关键词 multi-agent cooperation unmanned aerial vehicles(UAV) distributed algorithm complete coverage path planning(CCPP)
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COMPLETE KAHLER METRICS WITH POSITIVE HOLOMORPHIC SECTIONAL CURVATURES ON CERTAIN LINE BUNDLES(RELATED TO A COHOMOGENEITY ONE POINT OF VIEW ON A YAU CONJECTURE)
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作者 段晓曼 关庄丹 《Acta Mathematica Scientia》 SCIE CSCD 2024年第1期78-102,共25页
In this article,we study Kahler metrics on a certain line bundle over some compact Kahler manifolds to find complete Kahler metrics with positive holomorphic sectional(or bisectional)curvatures.Thus,we apply a strateg... In this article,we study Kahler metrics on a certain line bundle over some compact Kahler manifolds to find complete Kahler metrics with positive holomorphic sectional(or bisectional)curvatures.Thus,we apply a strategy to a famous Yau conjecture with a co-homogeneity one geometry. 展开更多
关键词 Kahler Metrics complete Riemannian metrics open complex manifolds holomorphic bisectional curvature C*bundle almost homogeneous manifolds
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Diagnostic significance of complete blood cell count and hemogramderived markers for neonatal sepsis at Southwest Public Hospitals,Ethiopia
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作者 Dereje Abebe Regassa Rahel Shumi Nagaash +1 位作者 Bisirat Fikadu Habtu Woyesa Beyene Haile 《World Journal of Clinical Pediatrics》 2024年第2期114-126,共13页
BACKGROUND Neonatal sepsis is defined as an infection-related condition characterized by signs and symptoms of bacteremia within the first month of life.It is the leading cause of mortality and morbidity among newborn... BACKGROUND Neonatal sepsis is defined as an infection-related condition characterized by signs and symptoms of bacteremia within the first month of life.It is the leading cause of mortality and morbidity among newborns.While several studies have been conducted in other parts of world to assess the usefulness of complete blood count parameters and hemogram-derived markers as early screening tools for neonatal sepsis,the associations between sepsis and its complications with these blood parameters are still being investigated in our setting and are not yet part of routine practice.AIM To evaluate the diagnostic significance of complete blood cell count hemogramderived novel markers for neonatal sepsis among neonates attending public hospitals in the southwest region of Oromia,Ethiopia,through a case control study.METHODS A case control study was conducted from October 2021 to October 2023 Sociodemographic,clinical history,and laboratory test results data were collected using structured questionnaires.The collected data were entered into Epi-data 3.1 version and exported to SPSS-25 for analysis.Chi-square,independent sample ttest,and receiver operator characteristics curve of curve were used for analysis.A P-value of less than 0.05 was considered statistically significant.RESULTS In this study,significant increases were observed in the following values in the case group compared to the control group:In white blood cell(WBC)count,neutrophils,monocyte,mean platelet volume(MPV),neutrophils to lymphocyte ratio,monocyte to lymphocyte ratio(MLR),red blood cell width to platelet count ratio(RPR),red blood width coefficient variation,MPV to RPR,and platelet to lymphocyte ratio.Regarding MLR,a cut-off value of≥0.26 was found,with a sensitivity of 68%,a specificity of 95%,a positive predictive value(PPV)of 93.2%,and a negative predictive value(NPV)of 74.8%.The area under the curve(AUC)was 0.828(P<0.001).For WBC,a cutoff value of≥11.42 was identified,with a sensitivity of 55%,a specificity of 89%,a PPV of 83.3%,and a NPV of 66.4%.The AUC was 0.81(P<0.001).Neutrophils had a sensitivity of 67%,a specificity of 81%,a PPV of 77.9%,and a NPV of 71.1%.The AUC was 0.801,with a cut-off value of≥6.76(P=0.001).These results indicate that they were excellent predictors of neonatal sepsis diagnosis.CONCLUSION The findings of our study suggest that certain hematological parameters and hemogram-derived markers may have a potential role in the diagnosis of neonatal sepsis. 展开更多
关键词 complete blood count Hemogram-derived marker NEONATE SEPSIS Ethiopia
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Prediction of pathological complete response and prognosis in locally advanced rectal cancer
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作者 Yi-Jun Xu Dan Tao +6 位作者 Song-Bing Qin Xiao-Yan Xu Kai-Wen Yang Zhong-Xu Xing Ju-Ying Zhou Yang Jiao Li-Li Wang 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第6期2520-2530,共11页
BACKGROUND Colorectal cancer is currently the third most common malignant tumor and the second leading cause of cancer-related death worldwide.Neoadjuvant chemoradiotherapy(nCRT)is standard for locally advanced rectal... BACKGROUND Colorectal cancer is currently the third most common malignant tumor and the second leading cause of cancer-related death worldwide.Neoadjuvant chemoradiotherapy(nCRT)is standard for locally advanced rectal cancer(LARC).Except for pathological examination after resection,it is not known exactly whether LARC patients have achieved pathological complete response(pCR)before surgery.To date,there are no clear clinical indicators that can predict the efficacy of nCRT and patient outcomes.AIM To investigate the indicators that can predict pCR and long-term outcomes following nCRT in patients with LARC.METHODS Clinical data of 128 LARC patients admitted to our hospital between September 2013 and November 2022 were retrospectively analyzed.Patients were categorized into pCR and non-pCR groups.Univariate analysis(using the χ^(2) test or Fisher’s exact test)and logistic multivariate regression analysis were used to study clinical predictors affecting pCR.The 5-year disease-free survival(DFS)and overall survival(OS)rates were calculated using Kaplan-Meier analysis,and differences in survival curves were assessed with the log-rank test.RESULTS Univariate analysis showed that pretreatment carcinoembryonic antigen(CEA)level,lymphocyte-monocyte ratio(LMR),time interval between neoadjuvant therapy completion and total mesorectal excision,and tumor size were correlated with pCR.Multivariate results showed that CEA≤5 ng/mL(P=0.039),LMR>2.73(P=0.023),and time interval>10 wk(P=0.039)were independent predictors for pCR.Survival analysis demonstrated that patients in the pCR group had significantly higher 5-year DFS rates(94.7%vs 59.7%,P=0.002)and 5-year OS rates(95.8%vs 80.1%,P=0.019)compared to the non-pCR group.Tumor deposits(TDs)were significantly correlated with shorter DFS(P=0.002)and OS(P<0.001).CONCLUSION Pretreatment CEA,LMR,and time interval contribute to predicting nCRT efficacy in LARC patients.Achieving pCR demonstrates longer DFS and OS.TDs correlate with poor prognosis. 展开更多
关键词 Locally advanced rectal cancer Neoadjuvant chemoradiotherapy Pathological complete response Carcinoembryonic antigen Inflammation-related markers Tumor deposit PROGNOSIS
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Advanced cervix cancer patient with chemotherapy-induced grade IV myelosuppression achieved complete remission with cadonilimab:A case report
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作者 Rui Zhu Tian-Ze Chen +1 位作者 Meng-Ting Sun Chun-Rong Zhu 《World Journal of Clinical Cases》 SCIE 2024年第8期1510-1516,共7页
BACKGROUND The prognosis for patients with advanced metastatic cervix cancer(MCC)is poor,and this disease continues to pose a considerable therapeutic challenge.Despite the administration of first-line regimens consis... BACKGROUND The prognosis for patients with advanced metastatic cervix cancer(MCC)is poor,and this disease continues to pose a considerable therapeutic challenge.Despite the administration of first-line regimens consisting of cisplatin,paclitaxel,and bevacizumab,survival rates for patients with metastasis remain poor.The emergence of bispecific antibodies(BsAbs)offers a novel treatment option for patients diagnosed with MCC.CASE SUMMARY In this report,we present a patient with MCC who was treated with cadonilimab monotherapy at a dose of 6 mg/kg every two weeks after chemotherapy was proven to be intolerable.The patient exhibited a sustained complete response for a duration of 6 months,demonstrating an optimistic outlook.CONCLUSION This case illustrates the considerable efficacy of cadonilimab for treating advanced MCC.Therefore,BsAb therapy is a promising strategy for effectively treating patients with advanced MCC and should be considered as an option when patients are intolerant to standard chemotherapy. 展开更多
关键词 Cadonilimab complete response Bispecific antibodies Recurrent or metastatic cervical cancer Programmed death protein 1 Cytotoxic T-lymphocyteassociated antigen-4 Case report
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An Evaluation of "Dialogue Completion" in English Testing
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作者 邵阳 《海外英语》 2011年第12X期133-134,共2页
To evaluate the validity of "dialogue completion" item in the language testing, this article explores three contradictions by analyzing aspects of its characters, content, validity and reliability. The findi... To evaluate the validity of "dialogue completion" item in the language testing, this article explores three contradictions by analyzing aspects of its characters, content, validity and reliability. The finding is that "dialogue completion" patten has unpredicted answer and should be avoided in the testing as much as possible. 展开更多
关键词 validity RELIABILITY DIALOGUE completion contradiciton
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Research and application of water jet technology in well completion and stimulation in China 被引量:9
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作者 Li Gensheng Huang Zhongwei Tian Shouceng Shen Zhonghou 《Petroleum Science》 SCIE CAS CSCD 2010年第2期239-244,共6页
In recent years, rapid progress in the use of high pressure water jets (HPWJ) has been made in oil and gas well drilling, completion, and stimulation; and good results have been achieved in field applications. Advan... In recent years, rapid progress in the use of high pressure water jets (HPWJ) has been made in oil and gas well drilling, completion, and stimulation; and good results have been achieved in field applications. Advances in technologies and developments of well completion and stimulation with hydrajet are reviewed in this paper. Experiments were conducted to study the characteristics of abrasive water jetting and to optimize jet parameters, which can provide methods for the well completion and hydrajet fracturing. Deep-penetrating hydrajet perforating can create a 2-3 m clean hole with a diameter of 20-35 mm. Multilayer hydrajet fracturing is a process whereby multiple layers are stimulated in a single run without using mechanical packers, thereby reducing operation procedure and risk. Multilateral radial wells can be drilled using hydraulic jetting up to 100 m in length. The technique to remove sand particles and plugs with rotating self-resonating cavitating water jets in horizontal wellbores has been developed and oilfield-tested, which shows promising, cost effective prospects. 展开更多
关键词 Water jet abrasive jet well completion PERFORATION STIMULATION horizontal drilling with hydrajet
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Is Minimizing Flow Completion Time the Optimal Way in Meeting Flow's Deadline in Datacenter Networks 被引量:3
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作者 XU Yakun LUO Hongbin REN Fei 《China Communications》 SCIE CSCD 2016年第S1期6-15,共10页
In modern datacenters, the most common method to solve the network latency problem is to minimize flow completion time during the transmission process. Following the soft real-time nature, the optimization of transpor... In modern datacenters, the most common method to solve the network latency problem is to minimize flow completion time during the transmission process. Following the soft real-time nature, the optimization of transport latency is relaxed to meet a flow's deadline in deadline-sensitive services. However, none of existing deadline-sensitive protocols consider deadline as a constraint condition of transmission.They can only simplify the objective of meeting a flow's deadline as a deadline-aware mechanism by assigning a higher priority for tight-deadline constrained flows to finish the transmission as soon as possible, which results in an unsatisfactory effect in the condition of high fan-in degree. It drives us to take a step back and rethink whether minimizing flow completion time is the optimal way in meeting flow's deadline. In this paper, we focus on the design of a soft real-time transport protocol with deadline constraint in datacenters and present a flow-based deadline scheduling scheme for datacenter networks(FBDS).FBDS makes the unilateral deadline-aware flow transmission with priority transform into a compound centralized single-machine deadlinebased flow scheduling decision. In addition, FBDS blocks the flow sets and postpones some flows with extra time until their deadlines to make room for the new arriving flows in order to improve the deadline meeting rate. Our simulation resultson flow completion time and deadline meeting rate reveal the potential of FBDS in terms of a considerable deadline-sensitive transport protocol for deadline-sensitive interactive services. 展开更多
关键词 DATACENTER NETWORKS DEADLINE PREEMPTIVE scheduling FLOW completion time
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A new mathematical model for horizontal wells with variable density perforation completion in bottom water reservoirs 被引量:2
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作者 Dian-Fa Du Yan-Yan Wang +2 位作者 Yan-Wu Zhao Pu-Sen Sui Xi Xia 《Petroleum Science》 SCIE CAS CSCD 2017年第2期383-394,共12页
Horizontal wells are commonly used in bottom water reservoirs,which can increase contact area between wellbores and reservoirs.There are many completion methods used to control cresting,among which variable density pe... Horizontal wells are commonly used in bottom water reservoirs,which can increase contact area between wellbores and reservoirs.There are many completion methods used to control cresting,among which variable density perforation is an effective one.It is difficult to evaluate well productivity and to analyze inflow profiles of horizontal wells with quantities of unevenly distributed perforations,which are characterized by different parameters.In this paper,fluid flow in each wellbore perforation,as well as the reservoir,was analyzed.A comprehensive model,coupling the fluid flow in the reservoir and the wellbore pressure drawdown,was developed based on potential functions and solved using the numerical discrete method.Then,a bottom water cresting model was established on the basis of the piston-like displacement principle.Finally,bottom water cresting parameters and factors influencing inflow profile were analyzed.A more systematic optimization method was proposed by introducing the concept of cumulative free-water production,which could maintain a balance(or then a balance is achieved)between stabilizing oil production and controlling bottom water cresting.Results show that the inflow profile is affected by the perforation distribution.Wells with denser perforation density at the toe end and thinner density at the heel end may obtain low production,but the water breakthrough time is delayed.Taking cumulative free-water production as a parameter to evaluate perforation strategies is advisable in bottom water reservoirs. 展开更多
关键词 Bottom water reservoirs Variable density perforation completion Inflow profile Cresting model Cumulative free-water production
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Novel Water-Based Drilling and Completion Fluid Technology to Improve Wellbore Quality During Drilling and Protect Unconventional Reservoirs 被引量:13
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作者 Guancheng Jiang Jinsheng Sun +5 位作者 Yinbo He Kaixiao Cui Tengfei Dong Lili Yang Xukun Yang Xingxing Wang 《Engineering》 SCIE EI CAS 2022年第11期129-142,共14页
The efficient exploration and development of unconventional oil and gas are critical for increasing the self-sufficiency of oil and gas supplies in China.However,such operations continue to face serious problems(e.g.,... The efficient exploration and development of unconventional oil and gas are critical for increasing the self-sufficiency of oil and gas supplies in China.However,such operations continue to face serious problems(e.g.,borehole collapse,loss,and high friction),and associated formation damage can severely impact well completion rates,increase costs,and reduce efficiencies.Water-based drilling fluids possess certain advantages over oil-based drilling fluids(OBDFs)and may offer lasting solutions to resolve the aforementioned issues.However,a significant breakthrough with this material has not yet been made,and major technical problems continue to hinder the economic and large-scale development of unconventional oil and gas.Here,the international frontier external method,which only improves drilling fluid inhibition and lubricity,is expanded into an internal-external technique that improves the overall wellbore quality during drilling.Bionic technologies are introduced into the chemical material synthesis process to imitate the activity of life.A novel drilling and completion fluid technique was developed to improve wellbore quality during drilling and safeguard formation integrity.Macroscopic and microscopic analyses indicated that in terms of wellbore stability,lubricity,and formation protection,this approach could outperform methods that use typical OBDFs.The proposed method also achieves a classification upgrade from environmentally protective drilling fluid to an ecologically friendly drilling fluid.The developed technology was verified in more than 1000 unconventional oil and gas wells in China,and the results indicate significant alleviation of the formation damage attributed to borehole collapse,loss,and high friction.It has been recognized as an effective core technology for exploiting unconventional oil and gas resources.This study introduces a novel research direction for formation protection technology and demonstrates that observations and learning from the natural world can provide an inexhaustible source of ideas and inspire the creation of original materials,technologies,and theories for petroleum engineering. 展开更多
关键词 Formation protection Wellbore quality Unconventional oil and gas Drilling and completion fluid BIONICS
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