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Temperature Drop of Molten Metals in Open Channels
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作者 Miguel A. Barron-Meza Joan Reyes-Miranda 《World Journal of Engineering and Technology》 2024年第3期493-500,共8页
The temperature drop of molten metal flowing in open channels is numerically determined. Rectangular, trapezoidal and triangular geometries are considered. The overall heat transfer coefficients for the bottom, side w... The temperature drop of molten metal flowing in open channels is numerically determined. Rectangular, trapezoidal and triangular geometries are considered. The overall heat transfer coefficients for the bottom, side walls and free surface of the channel have been taken from the literature. For each geometry, the volumetric flow rate, mean residence time and temperature drop as a function of the channel inclination angle were determined. The rectangular and trapezoidal geometries present the smallest temperature drops, while the triangular geometry presents the greatest temperature drop. The factors that most affect this drop are the value of the free surface area of the channel, and the average residence time of the molten metal in the channel. 展开更多
关键词 Free Surface Heat Transfer Molten Metal Open channel Geometry Residence Time Temperature Drop
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Effect of Mixed Vegetation of Different Heights on Open Channel Flows
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作者 Xiaonan Tang Yutong Guan +4 位作者 Ming Li Hanyi Wang Jiaze Cao Suyang Zhang Nanyu Xiao 《Journal of Geoscience and Environment Protection》 2023年第3期305-314,共10页
Vegetation of different heights commonly grows in natural rivers, canals and wetlands and affects the biodiversity and morphological process. The role of vegetation has drawn great attention in river ecosystems and en... Vegetation of different heights commonly grows in natural rivers, canals and wetlands and affects the biodiversity and morphological process. The role of vegetation has drawn great attention in river ecosystems and environmental management. Due to the complexity of the vegetated flow, most previous research focuses on the effect of uniformed one-layered vegetation on the flow structure and morphological process. However, less attention was paid to the impact of the mixing vegetation of different heights, which is more realistic and often occurs in natural riverine environments. This paper aims to investigate the effect of mixing three-layered vegetation on flow characteristics, particularly the velocity distrbution, via a novel experiment. Experiments were performed in a titling water flume fully covered with vegetation of three heights (10, 15 and 20 cm) arranged in a staggered pattern, which is partially submerged. Velocities at different positions along a half cross-section were measured using a mini propeller velocimeter. Observed results showed that the velocity has a distinct profile directly behind vegetation and behind the vegetation gap. The overall profile has two distinct reflections about ? below or near the top of short vegetation (h): the velocity remains almost constant in the bottom layer ( h) the velocities directly behind the middle after short vegetation increase much faster than those directly behind the short after tall vegetation. The finding in this study would help river riparian and ecosystem management. . 展开更多
关键词 Rigid Vegetation Mixed-Layered Vegetation RIPARIAN Velocity Distribution Submerged Flow Open channel
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Utility Impact below Bridge or Culvert Soffit on Open Channel Flow
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作者 Rodney McDermott Sarah Quinn 《Open Journal of Modern Hydrology》 2023年第4期193-210,共18页
The background to this research was a flooding incident that occurred in Bridgend, Co. Donegal, Ireland in August 2017. While several properties were flooded, a flooding case study of a single dwelling house adjacent ... The background to this research was a flooding incident that occurred in Bridgend, Co. Donegal, Ireland in August 2017. While several properties were flooded, a flooding case study of a single dwelling house adjacent to the Bridgend River at Riverdale, Bunamayne, Co. Donegal, Ireland is used herein. For this study the flooded site shall be referred to as the “Hegarty property”. A structure in the form of a stone arched culvert is located directly adjacent to the two-storey detached dwelling house on the Hegarty Property. While the culvert is referred to locally as a bridge, within this research the word culvert will be used in connection with the structure. The culvert has a concrete surrounded utility (watermain) crossing at a gradient below the culvert soffit on the upstream face of the structure. The utility obstructed flow through the culvert and contributed to the flooding event. Given the implication of climate change and the increased probability of more extreme flooding events, it was decided to explore the case study to ascertain the factors that contribute to flooding events when utilities are positioned at culvert or bridge structures. This work was completed to assist undergraduate students, researchers, and local authorities in a relatively unknown area of flood causation. 展开更多
关键词 UTILITY BRIDGE CULVERT Hydraulics FLOODING Climate Change & Open channel Flow
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A Practical Regular LDPC Coded Scheme for Physical-Layer Information Security
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作者 Du Junyi 《China Communications》 SCIE CSCD 2024年第5期190-201,共12页
In this paper,we aim to design a practical low complexity low-density parity-check(LDPC)coded scheme to build a secure open channel and protect information from eavesdropping.To this end,we first propose a punctured L... In this paper,we aim to design a practical low complexity low-density parity-check(LDPC)coded scheme to build a secure open channel and protect information from eavesdropping.To this end,we first propose a punctured LDPC coded scheme,where the information bits in a codeword are punctured and only the parity check bits are transmitted to the receiver.We further propose a notion of check node type distribution and derive multi-edge type extrinsic information transfer functions to estimate the security performance,instead of the well-known weak metric bit error rate.We optimize the check node type distribution in terms of the signal-to-noise ratio(SNR)gap and modify the progressive edge growth algorithm to design finite-length codes.Numerical results show that our proposed scheme can achieve a lower computational complexity and a smaller security gap,compared to the existing scrambling and puncturing schemes. 展开更多
关键词 extrinsic information transfer function physical layer scheme secure open channel security gap
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Theory of Flexural Shear, Bending and Torsion for a Thin-Walled Beam of Open Section
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作者 David W. A. Rees Abdelraouf M. Sami Alsheikh 《World Journal of Mechanics》 2024年第3期23-53,共31页
Aspects of the general Vlasov theory are examined separately as applied to a thin-walled channel section cantilever beam under free-end end loading. In particular, the flexural bending and shear that arise under trans... Aspects of the general Vlasov theory are examined separately as applied to a thin-walled channel section cantilever beam under free-end end loading. In particular, the flexural bending and shear that arise under transverse shear and axial torsional loading are each considered theoretically. These analyses involve the location of the shear centre at which transverse shear forces when applied do not produce torsion. This centre, when taken to be coincident with the centre of twist implies an equivalent reciprocal behaviour. That is, an axial torsion applied concentric with the shear centre will twist but not bend the beam. The respective bending and shear stress conversions are derived for each action applied to three aluminium alloy extruded channel sections mounted as cantilevers with a horizontal principal axis of symmetry. Bending and shear are considered more generally for other thin-walled sections when the transverse loading axes at the shear centre are not parallel to the section = s centroidal axes of principal second moments of area. The fixing at one end of the cantilever modifies the St Venant free angular twist and the free warping displacement. It is shown from the Wagner-Kappus torsion theory how the end constrained warping generates an axial stress distribution that varies with the length and across the cross-section for an axial torsion applied to the shear centre. It should be mentioned here for wider applications and validation of the Vlasov theory that attendant papers are to consider in detail bending and torsional loadings applied to other axes through each of the centroid and the web centre. Therein, both bending and twisting arise from transverse shear and axial torsion applied to each position being displaced from the shear centre. Here, the influence of the axis position upon the net axial and shear stress distributions is to be established. That is, the net axial stress from axial torsional loading is identified with the sum of axial stress due to bending and axial stress arising from constrained warping displacements at the fixing. The net shear stress distribution overlays the distributions from axial torsion and that from flexural shear under transverse loading. Both arise when transverse forces are displaced from the shear centre. 展开更多
关键词 Thin Wall Theory Cantilever Beam Open channel Section Principal Axes Flexure Transverse Shear TORSION Shear Centre Shear Flow WARPING Fixed-End Constraint
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Experimental study on influence of boundary on location of maximum velocity in open channel flows 被引量:5
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作者 Jing YAN Hong-wu TANG +2 位作者 Yang XIAO Kai-jie LI Zhi-Jun TIAN 《Water Science and Engineering》 EI CAS 2011年第2期185-191,共7页
The velocity dip phenomenon may occur in a part of or in the whole flow field of open channel flows due to the secondary flow effect. Based on rectangular flume experiments and the laser Doppler velocimetry, the influ... The velocity dip phenomenon may occur in a part of or in the whole flow field of open channel flows due to the secondary flow effect. Based on rectangular flume experiments and the laser Doppler velocimetry, the influence of the distance to the sidewall and the aspect ratio on the velocity dip is investigated. Through application of statistical methods to the experimental results, it is proposed that the flow field may be divided into two regions, the relatively strong sidewall region and the relatively weak sidewall region. In the former region, the distance to the sidewall greatly affects the location of maximum velocity, and, in the latter region, both the distance to the sidewall and the aspect ratio influence the location of the maximum velocity. 展开更多
关键词 velocity dip open channel flow location of maximum velocity sidewall effect aspect ratio
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Influence of deflection angles on flow behaviours in openchannel bends 被引量:2
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作者 LI Bing-dong ZHANG Xin-hua +1 位作者 TANG Han-song TSUBAKI Ryota 《Journal of Mountain Science》 SCIE CSCD 2018年第10期2292-2306,共15页
The deflection angle of a river bend plays an important role on behaviours of the flow within it, and a clear understanding of the angle's influence is significant in both theoretical study and engineering applica... The deflection angle of a river bend plays an important role on behaviours of the flow within it, and a clear understanding of the angle's influence is significant in both theoretical study and engineering application. This paper presents a systematic numerical investigation on effects of deflection angles(30°, 60°, 90°, 120°, 150°, and 180°) on flow phenomena and their evolution in open-channel bends using a Re-Normalization Group(RNG) κ-ε model and a volume of fluid(VOF) method. The numerical results indicate that the deflection angle is a key factor for flows in bends. It is shown that the maximum transverse slope of water surface occurs at the middle cross section of a bend, and it increases with the deflection angle. Besides a major vortex, or, the primary circulation cell near the channel bottom, a secondary vortex, or, an outer bank cell, may also appear above the former and near the outer bank when the deflection angle is sufficiently large, and it will gradually migrate towards the inner bank and evolve into an inner bank cell. The strength of the secondary circulations increases with the deflection angle. The simulation demonstrates that there is alow-stress zone on the bed near the outer bank and a high-stress zone on the bed near the inner bank, and both of them increase in size with the deflection angle. The maximum of shear stress on the inner bank increases nonlinearly with the angle, and its maximums on the outer bank and on the bed take place when the deflection angle becomes 120°. 展开更多
关键词 Open channel Deflection angle Transverse slope of water surface Secondary flow Shear stress
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Beneficial effects of adenosine triphosphate-sensitive K^+ channel opener on liver ischemia/reperfusion injury 被引量:3
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作者 Mateus Antunes Nogueira Ana Maria Mendona Coelho +4 位作者 Sandra Nassa Sampietre Rosely Antunes Patzina Fabiano Pinheiro da Silva Luiz Augusto Carneiro D'Albuquerque Marcel Cerqueira Cesar Machado 《World Journal of Gastroenterology》 SCIE CAS 2014年第41期15319-15326,共8页
AIM: To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury.
关键词 Liver ischemia/reperfusion DIAZOXIDE K+ channel opener Mitochondrial ATP-sensitive potassium channel Liver mitochondria
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Flow characteristics in curved open channel with partial suspended vegetation 被引量:1
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作者 ZHANG Qiao-ling JING He-fang +2 位作者 LI Chun-guang WANG Wei-hong ZHANG Wen-sheng 《Journal of Mountain Science》 SCIE CSCD 2022年第9期2715-2728,共14页
Suspended vegetation in open channels such as natural river,lake,reservoir usually affect the flow structure,causing the change of the water environment,sediment transport,bed deformation.In order to study the water f... Suspended vegetation in open channels such as natural river,lake,reservoir usually affect the flow structure,causing the change of the water environment,sediment transport,bed deformation.In order to study the water flow behavior in curved open channels under the influence of suspended vegetation,experiments were conducted in a Ushaped flume with 180°bend where the suspended vegetation substituted by cylindrical glass rods were partially placed.The particle image velocimeter(PIV)system was employed to measure the flow velocities of various cases with different vegetation arrangements and roots length.Comparison and analysis were conducted for measured data,such as water level,velocity,head loss,Reynolds stress,and turbulence kinetic energy(TKE)to obtain certain general rules of water flow in open curved channels with suspended vegetation.It can be found from the measured data that the water level and the head loss in the vegetation area are closely related to the arrangements of the suspended vegetation.Furthermore,the drag force of the vegetation can not only lead to smaller increments of longitudinal TKE above the vegetation tail than that below it,but also lead to the flow velocities in vegetation area much smaller than areas without vegetation.In addition,suspended vegetation weakens the vortex strength near the water surface and increases the vortex strength below the vegetation tail,and the flow velocity in the vegetation area has a close relationship with the suspended vegetation length in the water.Therefore,it can be concluded that the reasonable arrangements of suspended vegetation group in curved open channel can protect the concave bank from being scoured,and protect the convex bank from being deposited. 展开更多
关键词 Curved open channel PIV Suspended vegetation Vegetation arrangements Turbulence kinetic energy
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Prediction of boundary shear stress distribution in straight open channels using velocity distribution 被引量:1
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作者 Behzad Malvandi Mahmoud F.Maghrebi 《Water Science and Engineering》 EI CAS CSCD 2021年第2期159-166,共8页
Conventional methods for measuring local shear stress on the wetted perimeter of open channels are related to the measurement of the very low velocity close to the boundary.Measuring near-zero velocity values with hig... Conventional methods for measuring local shear stress on the wetted perimeter of open channels are related to the measurement of the very low velocity close to the boundary.Measuring near-zero velocity values with high fluctuations has always been a difficult task for fluid flow near solid boundaries.To solve the observation problems,a new model was developed to estimate the distribution of boundary shear stress from the velocity distribution in open channels with different cross-sectional shapes.To estimate the shear stress at a point on the wetted perimeter by the model,the velocity must be measured at a point with a known normal distance to the boundary.The experimental work of some other researchers on channels with various cross-sectional shapes,including rectangular,trapezoidal,partially full circular,and compound shapes,was used to evaluate the performance of the proposed model.Optimized exponent coefficients for the model were found using the multivariate Newton method with the minimum of the mean absolute percentage error(MAPE)between the model and experimental data as the objective function.Subsequently,the calculated shear stress distributions along the wetted perimeter were compared with the experimental data.The most important advantage of the proposed model is its inherent simplicity.The mean MAPE value for the seven selected cross-sections was 6.9%.The best results were found in the cross-sections with less discontinuity of the wetted perimeter,including the compound,trapezoidal,and partially full circular pipes.In contrast,for the rectangular cross-section with an angle between the bed and walls of 90°,MAPE increased due to the large discontinuities. 展开更多
关键词 Open channel Boundary shear stress Viscous shear stress Velocity distribution Velocity gradient
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The properties of dilute debris flow and hyper-concentrated flow in different flow regimes in open channels 被引量:1
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作者 LIU Yan WANG Hui-feng +2 位作者 CHEN Hua-yong HU Kai-heng WANG Xie-kang 《Journal of Mountain Science》 SCIE CSCD 2017年第9期1728-1738,共11页
Particle Image Velocimetry(PIV) technique was used to test the analogues of hyperconcentrated flow and dilute debris flow in an open flume. Flow fields, velocity profiles and turbulent parameters were obtained under d... Particle Image Velocimetry(PIV) technique was used to test the analogues of hyperconcentrated flow and dilute debris flow in an open flume. Flow fields, velocity profiles and turbulent parameters were obtained under different conditions. Results show that the flow regime depends on coarse grain concentration. Slurry with high fine grain concentration but lacking of coarse grains behaves as a laminar flow. Dilute debris flows containing coarse grains are generally turbulent flows. Streamlines are parallel and velocity values are large in laminar flows. However, in turbulent flows the velocity diminishes in line with the intense mixing of liquid and eddies occurring. The velocity profiles of laminar flow accord with the parabolic distribution law. When the flow is in a transitional regime, velocity profiles deviate slightly from the parabolic law. Turbulent flow has an approximately uniform distribution of velocity and turbulent kinetic energy. The ratio of turbulent kinetic energy to the kinetic energy of time-averaged flow is the internal cause determining the flow regime: laminar flow(k/K<0.1); transitional flow(0.1< k/K<1); and turbulent flow(k/K>1). Turbulent kinetic energy firstly increases with increasing coarse grain concentration and then decreases owing to the suppression of turbulence by the high concentration of coarse grains. This variation is also influenced by coarse grain size and channel slope. The results contribute to the modeling of debris flow and hyperconcentrated flow. 展开更多
关键词 Hyper-concentrated flow Debris flow Flow regime Velocity profile Turbulent kinetic energy Open channel
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Uniform Flow of Molten Metals in Rectangular Open Channels 被引量:1
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作者 Miguel A. Barron Joan Reyes Dulce Y. Medina 《World Journal of Engineering and Technology》 2022年第3期518-526,共9页
The flow of liquids in open channels has been studied since ancient Rome. However, the vast majority of published reports on flow in open channels are focused on the transport of drinking water and sewage disposal. Th... The flow of liquids in open channels has been studied since ancient Rome. However, the vast majority of published reports on flow in open channels are focused on the transport of drinking water and sewage disposal. The literature on the transport of molten metals in open channels is quite scarce. In this work, the uniform flow of pig iron and molten aluminum in rectangular open channels is studied. Specific energy curves are constructed and critical heights are analytically determined. The transition from subcritical to supercritical flow is analyzed as a function of the angle of inclination of the channel and the roughness of its walls. Manning’s equation is applied to the pig iron flow using data reported in the literature for molten aluminum. The need to correct the roughness coefficient for pig iron is observed in order to obtain results consistent with those previously reported. 展开更多
关键词 Critical Height Froude Number Molten Metal Flow Open channel Rectangular channel Uniform Flow
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A Pair of 3D Homochiral Coordination Polymers with Open Channels Constructed by Lactic Acid Derivative Ligands and In-situ Formed Anions 被引量:1
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作者 徐中轩 马钰璐 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2017年第4期671-678,共8页
With the help of in-situ formed CH_3COO- anion, a pair of 3D homochiral coordination polymers with open channels were constructed by the assembly of lactic acid derivative ligands, 1.4-DIB ligands and Cd(II) ions, n... With the help of in-situ formed CH_3COO- anion, a pair of 3D homochiral coordination polymers with open channels were constructed by the assembly of lactic acid derivative ligands, 1.4-DIB ligands and Cd(II) ions, namely [Cd3((R)-CIA)2(CH3CO2)_2(1.4-DIB)2(H2O)2]·x(Guest)(1-D) and [Cd3((S)-CIA)2(CH3CO2)2(1.4-DIB)2(H2O)2]·x(Guest)(1-L). They contain 1D interesting ladder-like Cd-(R)-CIA(3-) chains and exhibit SHG-active behavior and photoluminescent property. 展开更多
关键词 homochiral coordination polymers lactic acid derivative ligand open channel SHG-active behavior photoluminescent property
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BASIC EQUATIONS OF TURBULENT FLOW FOR VARIABLE DENSITY AND VARIABLE VISCOSITY NEWTONIAN FLUID IN OPEN CHANNEL
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作者 郑永刚 方铎 李桂芬 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 1997年第9期883-890,共8页
In this paper, using Navier-Stokes equations and Reynolds time-averaged rules, the turbulent motional differential equations of variable density and variable viscosity Newtonian fluid have been presented, and the turb... In this paper, using Navier-Stokes equations and Reynolds time-averaged rules, the turbulent motional differential equations of variable density and variable viscosity Newtonian fluid have been presented, and the turbulent motional differential equations of variable density and variable viscosity Newtonian fluid in open channel have been further proposed. The concepts of the density turbulence stress and the viscosity turbulence stress have been firstly presented in the paper. 展开更多
关键词 open channel variable viscosity fluid TURBULENCE basic equation Newtonian fluid
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Impact of depth ratio on flow structure and turbulence characteristics of compound open channel flows
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作者 Shao-wei Ding Cheng Zeng +2 位作者 Jie Zhou Ling-ling Wang Chen Chen 《Water Science and Engineering》 EI CAS CSCD 2022年第3期265-272,共8页
Compound open channel flows appear in most natural rivers are of great importance in river management and flood control.In this study,large eddy simulations were carried out to simulate the compound open channel flows... Compound open channel flows appear in most natural rivers are of great importance in river management and flood control.In this study,large eddy simulations were carried out to simulate the compound open channel flows with four different depth ratios(hr=0.10,0.25,0.50,and 0.75).The main flow velocity,secondary flow,Reynolds stress,and bed shear stress were obtained from numerical simulations.The depth-averaged stream wise momentum equation was used to quantify the lateral momentum exchange between the main channel and floodplain.The instantaneous coherent structures were presented by the Q criterion method.The impact of hr on flow structure and turbulence charac-teristics was analyzed.The results showed that with the increase of hr,the high velocity area in the main channel shifted to the floodplain,and the dip phenomenon became more obvious;the Reynolds stress largely contributed to the lateral momentum exchange within the flows near the side walls of floodplain;and the vortex structures were found to significantly increase in the floodplain region. 展开更多
关键词 Large eddy simulation Compound open channel Depth ratio Flow structure Turbulence characteristics
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Analytical solutions for transverse distributions of stream-wise velocity in turbulent flow in rectangular channel with partial vegetation
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作者 槐文信 耿川 +1 位作者 曾玉红 杨中华 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2011年第4期459-468,共10页
The theory of poroelasticity is introduced to study the hydraulic properties of the steady uniform turbulent flow in a partially vegetated rectangular channel. Plants are assumed as immovable media. The resistance cau... The theory of poroelasticity is introduced to study the hydraulic properties of the steady uniform turbulent flow in a partially vegetated rectangular channel. Plants are assumed as immovable media. The resistance caused by vegetation is expressed by the theory of poroelasticity. Considering the influence of a secondary flow, the momentum equation can be simplified. The momentum equation is nondimensionalized to obtain a smooth solution for the lateral distribution of the longitudinal velocity. To verify the model, an acoustic Doppler velocimeter (ADV) is used to measure the velocity field in a rectangular open channel partially with emergent artificial rigid vegetation. Comparisons between the measured data and the computed results show that the method can predict the transverse distributions of stream-wise velocities in turbulent flows in a rectangular channel with partial vegetation. 展开更多
关键词 theory of poroelasticity open channel flow VEGETATION secondary current depth-averaged velocity distribution
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Vertical rotation effect on turbulence characteristics in an open channel flow
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作者 邹立勇 柏劲松 +3 位作者 李步阳 谭多望 李平 刘仓理 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第3期1034-1040,共7页
This paper solves the three-dimensional Navier-Stokes equation by a fractional-step method with the Reynolds number Reτ=194 and the rotation number Nτ=0-0.12. When Nτ is less than 0.06, the turbulence statistics re... This paper solves the three-dimensional Navier-Stokes equation by a fractional-step method with the Reynolds number Reτ=194 and the rotation number Nτ=0-0.12. When Nτ is less than 0.06, the turbulence statistics relevant to the spanwise velocity fluctuation are enhanced, but other statistics are suppressed. When Nτ is larger than 0.06, all the turbulence statistics decrease significantly. Reynolds stress budgets elucidate that turbulence kinetic energy in the vertical direction is transferred into the streamwise and spanwise directions. The flow structures exhibit that the bursting processes near the bottom wall are ejected toward the free surface. Evident change of near-surface streak structures of the velocity fluctuations are revealed. 展开更多
关键词 vertical rotating open channel flow turbulence statistics ftow structure
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Origin of Erosion and Hydraulic Problems of the San Roque Underground Arched Culvert Channel and Its Relationship with the Maximum Flow Rate and the Maximum Permissible Velocity
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作者 Martín Mundo-Molina Daniel Hernández-Cruz 《Journal of Water Resource and Protection》 2020年第12期1123-1139,共17页
This work presents the hydrologic estimations of the hydraulic underground arched culvert channel (UACC) in Sabinal Basin, Chiapas, México and the hydrological problems associated with it, such as the erosion phe... This work presents the hydrologic estimations of the hydraulic underground arched culvert channel (UACC) in Sabinal Basin, Chiapas, México and the hydrological problems associated with it, such as the erosion phenomenon and abrasion cavity formation in it. On the other hand, the maximum flows that the UACC could transport were analyzed, concluding that it no longer has the hydraulic capacity to transport the flow rate associated to return periods equal to or greater than five years and that maximum permissible velocity UACC’s bottom is 3 m/s. 展开更多
关键词 Collapse Underground Arched Culvert channel Maximum Flow Rate Maximum Permissible Water Velocity Open channel Bottom Erosion
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Protective effect and mechanism of K_(ATp) channel opener on the sinoatrial node cells of neonatal rat cultured in simulated ischemia-reperfusion
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作者 宋治远 仝识非 钟理 《Journal of Medical Colleges of PLA(China)》 CAS 2003年第4期205-208,共4页
Objective: To study the effect of KATp channel opener and its possible mechanism on the sinoatrial node cells of neonatal rats which were cultured under simulated ischemia-reperfusion. Methods: Freshly isolated sinoat... Objective: To study the effect of KATp channel opener and its possible mechanism on the sinoatrial node cells of neonatal rats which were cultured under simulated ischemia-reperfusion. Methods: Freshly isolated sinoatrial node (SAN) cells of neonatal rats were purified and cultured for 2 d, and then they were randomly divided into the control, simulated ischemia-reperfusion group (I/R group) , group intervened with KATp channel opener pinacidil (P + I/R group), KATP Channel blocking agent 5-HD (5-HD + I/R group) , and group with the 2 agents at same time (5-HD + P + I/R group) . The survival rate of cells was measured by flow cytometry and the content of intracellular calcium in the cells of each group was detected with laser confocal microscopy. Results: ① The survival rate of SAN cells in I/R group [ (51. 79±6. 28)% ] was remarkably significantly lower than in control [ (95. 08±10. 48)% ] (P < 0.001), and very significantly lower than in P + I/R group [ (63. 77±5. 35) % ] (P<0.01), however, those of 5-HD + P + I/R group [(52. 88±6. 25)% ] and 5-HD+I/R group [ (53. 16±5. 35)% ] was significantly lower compared with that in P + I/R group (P <0. 01) ; ② When the average fluorescence intensity of sinoatrial node cells in the control was regarded as 100% , the relative fluorescence intensities of each group were: ( 374±52) % in I/R group, significantly higher than that of control (P <0. 01) ; ( 162±20)% in P + I/R group, declining significantly than that of I/R group (P<0.01); (385?6)% in 5-HD+ P + I/R group and (379±44)% in 5-HD + I/R group, increasing significantly than that of I/R group (P<0.01). Conclusion: ① Simulated ischemia-reperfusion can significantly reduce the survival rate of SAN cells, and can also lead to the overload of intracellular calcium in them.② KATp channel opener, pinacidil, exerts protective effect on the cells under simulated ischemia-reperfusion, which may be associated with the decrease of intracellular calcium loading in them. 展开更多
关键词 sinoatrial node ischemia-reperfusion KATP channel opener intracellular calcium
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Unsteady Non-Uniform Flow of Molten Metals in Rectangular Open Channels
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作者 Miguel A. Barron Joan Reyes Dulce Y. Miranda 《World Journal of Engineering and Technology》 2022年第3期593-604,共12页
In the metallurgical industries, it is very important to characterize the flow of molten metals in open channels given that they are transported through these devices to different plant sections. Howeve... In the metallurgical industries, it is very important to characterize the flow of molten metals in open channels given that they are transported through these devices to different plant sections. However, unlike the flow of water which has been studied since ancient times, the flow of molten metals in open channels has received little attention. The unsteady non-uniform flow of blast furnace molten pig iron in a rectangular open channel is analyzed in this work by numerical solution of the Saint-Venant equations. The influence of mesh size on the convergence of molten metal height is studied to determine the proper mesh and time step sizes. A sinusoidal inflow pulse is imposed at the entrance of the channel in order to analyze the propagation of the resulting wave. The influence of the angle of inclination of the channel and the roughness coefficient of the walls on the amplitude and the dynamic behavior of the height of the molten metal are analyzed. Phase portraits of the channel state variables are constructed and interpreted. Numerical simulations show that as the angle of inclination of the channel increases, the amplitude of the formed wave decreases. From 10 degrees onwards, the peak of the wave descends even below the initial height. On the other hand, the roughness coefficient affects the molten pig iron height profiles in an inverse way than the angle of inclination. The amplitude of the formed wave increases as the roughness coefficient increases. 展开更多
关键词 Molten Metals Flow Non-Uniform Flow Open channels Pig Iron Transport Saint-Venant Equations Sinusoidal Pulse Unsteady Flow
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