Causal relationship between feelings and cognitive decline:An univariable and multivariable Mendelian randomization study

BACKGROUND While the impact of depression on cognition is well-documented,the relationship between feelings and cognition has received limited attention.AIM To explore the potential association between feelings and cognition with a twosample Mendelian randomization(MR)analysis.METHODS Our analysis utilized genome-wide association data on various feelings(fed-up feelings,n=453071;worrier/anxious feelings,n=450765;guilty feelings,n=45-0704;nervous feelings,n=450700;sensitivity/hurt feelings,n=449419;miserableness,n=454982;loneliness/isolation,n=455364;happiness,n=152348)in the European population and their impact on cognitive functions(intelligence,n=269867).Conducting a univariable MR(UVMR)analysis to assess the relationship between feelings and cognition.In this analysis,we applied the inverse variance weighting(IVW),weighted median,and MR Egger methods.Additionally,we performed sensitivity analysis(leave-one-out analysis),assessed heterogeneity(using MR-PRESSO and Cochran’s Q test),and conducted multiple validity test(employing MR-Egger regression).Subsequently,a multivariable MR(MVMR)analysis was employed to examine the impact of feelings on cognition.IVW served as the primary method in the multivariable analysis,complemented by median-based and MR-Egger methods.RESULTS In this study,UVMR indicated that sensitivity/hurt feelings may have a negative causal effect on cognition(OR=0.63,95%CI:0.43-0.92,P=0.017).After adjustment of other feelings using MVMR,a direct adverse causal effect on cognition was observed(OR_(MVMR)=0.39,95%CI:0.17-0.90,P_(MVMR)=0.027).While a potential increased risk of cognitive decline was observed for fed-up feelings in the UVMR analysis(ORUVMR=0.64,95%CI:0.42-0.97,PUVMR=0.037),this effect disappeared after adjusting for other feelings(OR_(MVMR)=1.42,95%CI:0.43-4.74,P_(MVMR)=0.569).These findings were generally consistent across MV-IVW,median-based,and MR-Egger analyses.MR-Egger regression revealed pleiotropy in the impact of worrier/anxious feelings on cognition,presenting a challenge in identifying the effect.Notably,this study did not demonstrate any significant impact of guilty feelings,nervous feelings,miserableness,or loneliness/isolation on cognition.Due to a limited number of instrumental variables for happiness,this study was unable to analyze the relationship between happiness and cognition.CONCLUSION This MR study finds that sensitivity/hurt feelings are associated with cognitive decline,while the link between worrier/anxious feelings and cognition remains inconclusive.Insufficient evidence supports direct associations between happiness,guilty feelings,nervous feelings,miserableness,loneliness/isolation,and cognition.

基于Openness可视化参数的二维地貌显示

Openness是一种二维地貌的可视化参数,不受光源设置和邻近地形遮蔽的影响,更强调地形的凹凸,使得直观的立体感更强。该参数不仅可以从多种来源的DEM数据计算获取,也可以用于不同精细程度的地貌分析。闽江入海口地区具有丰富的构造地貌类型,基于SRTM(90 m)高程数据计算该地区的Openness参数,探讨该参数在地形地貌方面的初步应用。通过闽江入海口地区构造地貌的分析结果表明,Openness参数方法比传统的地形晕渲等常用二维可视化方法编制的图件效果更好,更强调地形的凹凸感,能够更详细地反映实际地形地貌的细节。

情绪与情绪调节策略对知晓感(Feeling-of-Knowing)判断的影响

本研究通过两个实验来研究情绪和情绪调节策略对知晓感判断的影响。在实验一中,通过让被试观看影片片段,激发相应的情绪状态,然后对不同情绪的词对做知晓感判断;在实验二中,通过观看影片诱发被试的负性情绪,然后采用不同情绪调节策略对被试的情绪状态进行调节并对不同情绪词对做知晓感判断。结果表明:1) 情绪状态和词对的情绪性质对FOK的判断等级和准确性存在影响,表现为在中性状态下,中性词对的判断等级和准确性均高于情绪词对;2) 情绪调节策略对FOK的判断等级产生影响,评价忽视策略和表情宣泄策略条件下被试的FOK判断值显著高于评价重视和表达抑制;3) 情绪调节策略对FOK判断准确性也存在影响,评价重视和评价忽视两种调节策略下被试的FOK判断准确性显著高于表情宣泄和表情抑制策略。

On Aesthetic Feelings of Synaesthesia

Synaesthesia is both a common daily life phenomenon and a controversial rhetoric one.Respective evidence may be found in 'Wounded fingers may cause pain in heart' and 'The breeze blows away birds' sweet voice from under the flower'.Other examples,like 'the liquid stillness of the night,noise color,sweet voice,icy look,sharp cry,sour remark,oily-tongued…' are so frequently seen in both Chinese and foreign poems especially classic poems.Without doubt,use of synaesthesia blows a fresh air into essay and poem writing,let alone the accurate and aesthetic feelings it arouses among readers.However,when people try to find out the reason why it can arouse such aesthetic feelings,they seem to encounter difficulties.This paper makes an attempt to offer a different explanation based on psychological analysis.

On loan words between English and Chinese——Discussion about the openness and assimilation of the words system

This paper mainly discusses the openness and assimilation of the words system from the viewpoint of loan words between English and Chinese.Both the history of loan words and the ways of borrowing words in English and Chinese have shown us the strong abilities of languages.

Government Data Openness and Coverage. How do They Affect Trust in European Countries?

Purpose: This paper aims to assess if the extent of openness and the coverage of data sets released by European governments have a significant impact on citizen trust in public institutions.Design/methodology/approach: Data for openness and coverage have been collected from the Open Data Inventory 2018(ODIN), by Open Data Watch;institutional trust is built up as a formative construct based on the European Social Survey(ESS), Round 9. The relations between the open government data features and trust have been tested on the basis of structural equation modelling(SEM).Findings: The paper reveals that as European governments improve data openness, disaggregation, and time coverage, people tend to trust them more. However, the size of the effect is still small and, comparatively, data coverage effect on citizens' confidence is more than twice than the impact of openness.Research limitations: This paper analyzes the causal effect of Open Government Data(OGD) features captured in a certain moment of time. In upcoming years, as OGD is implemented and a more consistent effect on people is expected, time series analysis will provide with a deeper insight.Practical implications: Public officers should continue working in the development of a technological framework that contributes to make OGD truly open. They should improve the added value of the increasing amount of open data currently available in order to boost internal and external innovations valuable both for public agencies and citizens.Originality/value: In a field of knowledge with little quantitative empirical evidence, this paper provides updated support for the positive effect of OGD strategies and it also points out areas of improvement in terms of the value that citizens can get from OGD coverage and openness.

SEMI-OPENNESSAND ALMOST-OPENNESS OF INDUCED MAPPINGS

Given a mapping f between continua.Let 2f and C(f) mean the induced mappings between hyperspaces.Relations are studied under the conditions:f is semi-open(almost open,respectively),2f is semi-open(almost open,respectively) and C(f) is semi-open(almost open,respectively).

Cross-Lagged Relationship between Physical Activity Time,Openness and Depression Symptoms among Adolescents:Evidence from China

The relationship between physical activity time,openness and depression symptoms among adolescents is a cutting-edge research direction in the field,yet it remains unclear.This study is based on a sample of 7924 students from a nationally representative China Education Panel Survey database and examines the bidirectional relationships between physical activity time,openness and depression symptoms among Chinese adolescents.Descriptive analysis showed that during the 7th and 8th grades,the average physical activity time decreased to less than one hour per day,accompanied by a decreasing trend in openness and a slight worsening in depression symptoms.Correlation analysis showed a significant negative correlation between physical activity time and depression symptoms,a significant positive correlation between physical activity time and openness,and a significant negative correlation between depression symptoms and openness.The results from cross-lagged models indicated a bidirectional relationship between physical activity time and openness,with physical activity time significantly positively predicting openness in the following year and openness significantly positively predicting physical activity time in the following year.In addition,depression symptoms had a unidirectional negative predictive effect on openness.The conclusions provide empirical evidence for education administration and schools to promote the physical and mental health development of adolescents worldwide.

The Global Value ofMencius＇s Ideas on Moral Feeling and Reason： Reinterpreting the Feeling of Compassion From the Perspective of the Philosophy of Emotion

Amid the recent global upsurge of studies on the philosophy of emotion, a reinterpretation of traditional Confucian philosophy, especially Mencius＇s ideas on the siduan （Four Original Sources） of morality, may shed new light on the subject in comparative philosophy. This paper probes the structure of moral feeling and reason described by Mencius＇s from five perspectives： （1） In view of the relationship between feeling and reason, is it better to use the expression ＂siduan＂ or the expression ＂sixin （Four Heart-minds）＂？ （2） In view of dispositional feeling, what are the four original sources？ （3） In view of moral feeling, what are the structural order of the four sources and the corresponding procedure of reasoning of four heart-minds of Humanity？ （4） In view of positive feeling, how does moral feeling grow out of the goodness of human nature？ （5） What is the global value of Mencius＇s ideas on human moral feeling？ The author concludes that Mencius＇s thought on moral feeing has a global value and cross-cultural significance, and that Chinese wisdom is more than regional but universally applicable. The structure of moral feeling and reason that Mencius identified is in accordance with the principles ofzhiliang （grasping the two poles of the beginning and the end） and yongzhong （emloying the middle）. The principles ofzhiliang and yongzhong are true universal wisdoms of Confucianism, which should be rekindled today. From a practical point of view, ＂the Way begins from moral feelings,＂ and Confucius and Yah Hui＇s seeking the simple, virtuous life is an ideal model of emotional well-being.

A terrain openness index for the extraction of karst Fenglin and Fengcong landform units from DEMs

The Fenglin and Fengcong landform units are considered to be an important representation for defining the degree of development of Karst landforms. However, these terrain features have been proven difficult to delineate and extract automatically because of their complex morphology. In this paper, a new method for identifying the Fenglin and Fengcong landform units is proposed. This method consists of two steps:(1) terrain openness calculation and(2) toe line extraction. The proposed method is applied and validated in the Karst case area of Guilin by using ASTER GDEM with one arc-second resolution. The openness of both the positive and negative terrain and a threshold were used to extract toe lines for segmenting depressions and pinnacles in Fenglin and Fengcong landforms. A comparison between the extracted Fenglin and Fengcong landform units and their real units from high resolution images wascarried out to evaluate the capability of the proposed method. Results show the proposed method can effectively extract the Fenglin and Fengcong landform units, and has an overall accuracy of 93.28%. The proposed method is simple and easy to implement and is expected to play an important role in the automatic extraction of similar landform units in the Karst area.

基于CAPE-OPEN标准的简捷炼油过程建模及常减压蒸馏流程在线模拟

简捷炼油过程模型广泛应用于运行监测、在线计算、实时优化等领域,但大多数模型只是将输入、输出变量进行关联,无法计算出各组分流量组成,难以集成在模拟软件中进行全流程模拟。本研究简化了炼油分离过程,开发了基于CAPE-OPEN标准的简捷炼油塔模型。首先,将炼油过程简化为连续的分离单元,根据实际产品数据校正模型参数,实现某一实际工况流程模拟;其次,将模型参数与实际工况操作变量数据相结合,采用径向基函数插值确定操作变量对模型参数的影响关系,实现多种工况流程模拟;最后,通过常减压蒸馏工业装置实例的3种工况进行验证。结果表明:各工况模拟结果与Aspen计算结果相比,初馏塔塔顶油馏出温度点偏差大多在2%以内,常减压蒸馏塔各侧线油的馏出温度点平均偏差在3%以内;与实际结果相比,平均误差都在5%以内,符合工程允许误差范围要求。所建模型的计算速度快,各塔均在0.2 s左右完成计算,适用于在线生产、调度等。

A Study on Feelings of Worriment Due to Middle-Sized Robot in Living Space

Recently, the demand of services for architectural space is more increasing due to the diversification and complication of people＇s needs. In this research, it is assumed that the robot will support people＇s various needs and people＇s lives in the near future. In this study, the authors investigated the relationship between a robot and a person in quasi space close to actual life space. The authors carried out an experiment to clarify the feelings of worriment due to a robot in the living room in the case of Japanese males. This research aims to establish architecture techniques for robots and humans living together. In this experiment, the robot approached a male sitting on a sofa in quasi space. At different distances between the robot and the male, the subject evaluated his feelings of worriment from ＂no worriment＂ to ＂worriment＂ in five steps from one to five. The robot used in this experiment is middle-sized （380 mm （L） × 380 mm （W） × 350 mm （H））. In this experiment, it is considered that the robot asks for help outside when an emergency occurs. In this experiment, the authors had three situations for the subject： watching television, reading a magazine and just sitting.

我国高质量教育资源供给机制创新与路径研究——来自美国“#GoOpen”计划的启示

数字化是当下教育改革的重点,也是未来教育发展的趋势。无论是作为“十四五”规划中的战略举措,还是党的二十大中提出的必然要求,构建数字化教育资源为主体的高质量教育资源体系在当下具有必要性与迫切性。美国#GoOpen计划自实施以来,在教育资源数字化、个性化、均等化三个方面均取得了一定成果。通过对该计划官方文件与政策进行解读,对其内涵与特点进行分析,我国在进行高质量教育资源建设及其供给路径探究过程中应当重视统筹规划,循序渐进,同时完善多重考核与评估机制,结合社会多方力量,保证每个学习者的享有权利,最终走向教育公平,共同发展。

The Study on Trade Policy and Openness of Mongolia： Influences on Trade Flows Between China-Mongolia-Russia （Past and Future）

This paper aimed to highlight the effects of conflict in Mongolia on trade policy and openness, by estimating the trade flows with neighbor countries （China and Russia）. Fourteen years＇ （2000-2013） data of Mongolian imports and exports were collected and gone through principal component analysis （PCA） and empirical analysis for grouping various trades with China and Russia. The empirical analysis identified the determining factors of Mongolian trade flow and openness with China and Russia. Empirical analysis evidenced that Mongolian trade and openness policy raised bilateral trade between China and Russia, leaving a great influence on economic size. Two main questions represented as empirically tested by each sample country. How did Mongolian trade policy and openness influence trade flows between China and Russia and economic growth of Mongolia？ Did Mongolian trade policy and the bilateral trade with China and Russia increase on trade openness？ Finally, the study focused on the forecasts from 2016 to 2018 to examine Mongolian trade flows with China and Russia using ordinary least squares method and autoregressive-moving-average （ARMA） model. China-Mongolia-Russia trade flows will continue to dominate during the forecasted period. As shown by the structure of export and import, goods with China and Russia influenced the mutual trade amount. Moreover, China and Russia traded to continue with Mongolia for goods in long run. Trade policy and openness, the major contributor in Mongolian economy, are significantly playing roles in trade and economy.

The Openness Degree Study of the Jiaoshiba Shale Gas, Sichuan Basin, China–Potential Factor Responsible for Reversed Isotope Series

Objective Reversed alkane δ;C and δ;H values in many prolific shale plays all over the world have aroused much attention in the study of the formation mechanism of reversed isotope series in alkanes in the past few years（Zou Caineng et al., 2016）. Although many researchers have put forward different hypotheses, the mechanism has not been well understood yet. The openness degree of oil and gas system

Capital Account Openness,Exchange Rate Volatility and Economic Growth:International Experiences and Implications

Based on the Barro classical growth model, this paper introduces capital account openness and exchange rate volatility to conduct an empirical analysis using the panel data of 182 countries(regions) during 1970-2013 to examine the combined effects of capital account openness and exchange rate risks on economic growth. Our findings are as follows:(1) Without considering exchange rate volatility, capital account openness is subject to a threshold effect, i.e. capital account openness significantly promotes the economic growth of middle-and high-income countries but exerts the opposite effect on low-income countries; and(2) after exchange rate volatility is taken into account, the growth effect of capital account openness is reduced and the greater the exchange rate volatility is, the smaller the marginal effect of capital account openness will be; sample-specific results also proved the existence of the threshold effect. This paper offers the following implications:(1) The effect of capital account openness can be better examined based on risk factors;(2) moderately controlling exchange rate volatility is conducive to acquiring greater benefits from capital account openness; and(3) the threshold effect of capital account openness cannot be overlooked.

Construction of an evaluation system for information openness of local governments

Evaluating government openness is important in monitoring government performance and promoting government transparency. Therefore, it is necessary to develop an evaluation system for information openness of local governments. In order to select evaluation indicators, we conducted a content analysis on current evaluation systems constructed by researchers and local governments and the materials of a case study on a local government. This evaluation system is composed of 5 first-tier indicators, 30 secondtier indicators and 69 third-tier indicators. Then Delphi Method and Analytic Hierarchy Process(AHP) Method are adopted to determine the weight of each indicator. At last, the practicability of the system is tested by an evaluation of the local government of Tianjin Binhai New Area, which has been undergoing administrative reform and attempting to reinvent itself in the past 5 years.

基于YOLO-OpenMax的水声通信信号开集识别方法

水声通信信号调制方式随着技术进步从典型的传统调制方式发展为水声通信机厂商私有开发的新型调制方式,这使得现有的水声通信信号闭集调制识别技术实用性受到制约,但现阶段鲜有研究基于深度学习的水声通信信号调制方式的开集识别方法。针对此现状,提出一种基于YOLO图像检测识别网络和OpenMax模型的开集识别方法。利用YOLOv5网络的输出特点,将传统OpenMax模型的处理方法进行改进,提出一种两步测试方法,实现了在多径信道下的水声通信信号的开集识别。仿真实验表明:在归一化系数为0.5,信噪比等于10 dB条件下的归一化开集识别准确率达到90%以上,实测数据同样验证了本文方法的有效性。

Negative feelings experienced by people with mental disorder in the workplace: A qualitative study

Mental disorders are a significant cause of disability and loss of workplace productivity. Many people with mental illness want to work. Occupational health in the world has to face up to psychosocial risks to protect the health of employees. My study aims are to improve negative feelings in work place and work functioning and to stimulate better coping mechanisms. Participants were collected from “Mental health daycare facility”, “Regional living assistance center” and “B-type employment assistance office” in Japan. I took interviews with 25 members. The content of the interviews was categorized about negative feelings in work place. A total of 33 small category negative feelings of mental disorder were extracted and were classified into 11 subcategories. These subcategories were then classified into two higher-level categories: inward-directed feelings and outward-directed feelings. Inward-directed feelings include “reserve or timidity,” “hesitation about being open about the illness,” “anxiety about being dismissed,” “regrets about resigning,” “sense of isolation,” “feelings of remorse,” and “suffering.” Outward-directed feelings include “failure in interpersonal relationships,” “distrust,” “frustrations,” “negative feelings toward those with mental disorder.” Employment has been linked to having better social networks, to enhanced quality of life and to overall wellbeing. We will have to defend them legally. The legal and moral obligations placed on the employer require that it provides a healthy, harassment-free work environment.

Serum 17β-estradiol and oral dryness feeling in menopause

The aim of this study was to compare serum 17β-estradiol of menopausal women with/without Oral Dryness (OD) feeling, and evaluate the re-lationship between serum 17β-estradiol and severity of OD feeling. A case-control study was carried out on 70 selected menopausal women aged 40 - 77 years with or without OD feeling (35 as case, 35 as control) conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. Xerostomia inventory (XI) score was used as an index of OD feeling severity. The serum 17β-estradiol concentration was measured by an enzyme immunoassay kit (ELISA). Statistical analysis of Student’s t-test and Spearman correlation coefficient was used. The mean serum concentration of 17β-estradiol was significantly lower in case than control. There was a significant negative correlation between XI score and concentration of 17β-estradiol in menopausal women (r = –0.311, P = 0.004). It seems that there is a negatively slight correlation between OD feeling severity and serum 17β-estradiol in menopausal women.