[目的]利用眼前段光学相干断层扫描仪（AS-OCT）观察原发性急性闭角型青光眼（APACG）和原发性慢性闭角型青光眼（CPACG）手术周边虹膜切除（SPI）前后眼前段结构的改变.[方法]连续性收集周边虹膜粘连＜6个钟点的、性别年龄匹配的APACG...[目的]利用眼前段光学相干断层扫描仪（AS-OCT）观察原发性急性闭角型青光眼（APACG）和原发性慢性闭角型青光眼（CPACG）手术周边虹膜切除（SPI）前后眼前段结构的改变.[方法]连续性收集周边虹膜粘连＜6个钟点的、性别年龄匹配的APACG发作期患者37例（37眼）及CPACG患者25例（25眼）,于SPI术前及术后1月行AS-OCT检查.比较术前及术后的中央前房深度（ACD）、房角开放距离（AOD）、小梁网虹膜间面积（TISA）、房角隐窝面积（ARA）、前房宽度（ACW）、前房容积（ACV）和晶状体矢高（CLR）的差异.[结果]与术前相比,APACG眼术后较术前AOD（0.096±0.063 vs 0.052±0.065,mm）、TISA（0.054±0.024 vs 0.030±0.029,mm2）、ARA（0.095±0.042 vs 0.059±0.057,mm2）和ACV（90±17 vs 73±17,mm3）增加（P＜ 0.001-0.032）,而ACD、ACW及CLR无明显变化（P=0.102 ～ 0.609）;CPACG眼术后较术前ARA （0.078±0.036 vs 0.065±0.024,mm2）及ACV（91±22 vs 83±22,mm3）明显增加（P=0.042和＜0.001）,而AOD、TISA、ACD、ACW和CLR无明显变化（P=0.102-0.774）.[结论]周边虹膜切除术可使APACG的房角开放和前房容积增加,使CPACG的前房容积增加,但不能改变APACG和CPACG眼的中央前房深度和晶状体的相对位置和CPACG眼的房角参数.展开更多
Monosaccharides are one of the most important structural components of biomolecules, such as polysac- charides, nucleic acids, glycolipids and glycoproteins. In structural analysis of polysaccharides and gly- coconjug...Monosaccharides are one of the most important structural components of biomolecules, such as polysac- charides, nucleic acids, glycolipids and glycoproteins. In structural analysis of polysaccharides and gly- coconjugates, the absolute configurations （D or L） of the constituent monosaccharides are usually deter- mined by measurement of the optical rotation, CD spectra or characteristic chromatographic retention behavior. However, each method has its unique advantages and limitations which should be considered while using them. In this review, an overview of the different methods for the determination of absolute configuration of monosaccharides and their underlying principles are summarized to serve as a reference for researchers.展开更多
文摘[目的]利用眼前段光学相干断层扫描仪（AS-OCT）观察原发性急性闭角型青光眼（APACG）和原发性慢性闭角型青光眼（CPACG）手术周边虹膜切除（SPI）前后眼前段结构的改变.[方法]连续性收集周边虹膜粘连＜6个钟点的、性别年龄匹配的APACG发作期患者37例（37眼）及CPACG患者25例（25眼）,于SPI术前及术后1月行AS-OCT检查.比较术前及术后的中央前房深度（ACD）、房角开放距离（AOD）、小梁网虹膜间面积（TISA）、房角隐窝面积（ARA）、前房宽度（ACW）、前房容积（ACV）和晶状体矢高（CLR）的差异.[结果]与术前相比,APACG眼术后较术前AOD（0.096±0.063 vs 0.052±0.065,mm）、TISA（0.054±0.024 vs 0.030±0.029,mm2）、ARA（0.095±0.042 vs 0.059±0.057,mm2）和ACV（90±17 vs 73±17,mm3）增加（P＜ 0.001-0.032）,而ACD、ACW及CLR无明显变化（P=0.102 ～ 0.609）;CPACG眼术后较术前ARA （0.078±0.036 vs 0.065±0.024,mm2）及ACV（91±22 vs 83±22,mm3）明显增加（P=0.042和＜0.001）,而AOD、TISA、ACD、ACW和CLR无明显变化（P=0.102-0.774）.[结论]周边虹膜切除术可使APACG的房角开放和前房容积增加,使CPACG的前房容积增加,但不能改变APACG和CPACG眼的中央前房深度和晶状体的相对位置和CPACG眼的房角参数.
基金supported by State Key Program of National Natural Science Foundation of China (grant number 81430095)
文摘Monosaccharides are one of the most important structural components of biomolecules, such as polysac- charides, nucleic acids, glycolipids and glycoproteins. In structural analysis of polysaccharides and gly- coconjugates, the absolute configurations （D or L） of the constituent monosaccharides are usually deter- mined by measurement of the optical rotation, CD spectra or characteristic chromatographic retention behavior. However, each method has its unique advantages and limitations which should be considered while using them. In this review, an overview of the different methods for the determination of absolute configuration of monosaccharides and their underlying principles are summarized to serve as a reference for researchers.
